Abstract：
:Colloidal carbon was injected intravenously into young rats to label circulating monocytes before making a stab wound in the brain. The rats were killed 3-16 days after the stab wound. Demonstration of non-specific esterase, thiamine pyrophosphatase and 5'-nucleotidase was carried out on the carbon-labelled macrophages at the site of lesion at various survival times. In rats killed 3-5 days after the injury numerous carbon-labelled macrophages were present in the needle passage as well as in the marginal area of the lesion and they showed a positive reaction for non-specific esterase. The reaction of the enzyme was found in some of the dense bodies in the form of punctate precipitates. The reaction for thiamine pyrophosphatase was seen in the Golgi saccules as well as on the plasma membrane, although in the latter the reaction was weaker. Intense reaction for 5'-nucleotidase was localised over the plasma membrane as well as over the dense bodies. The carbon-labelled macrophages displaying the activities of the above enzymes in the 3-5 days postoperative group were of the round type. However, in the 8-16 postoperative days animals, the cells were either oval or had assumed an elongated outline resembling the microglial cells seen in the tissue taken from the normal side. It is concluded that circulating monocytes are a main source of brain macrophage in traumatic brain lesions. In the healing process of the wound some of the cells regress to become microglial cells as shown by the presence of the carbon particles as well as non-specific esterase, thiamine pyrophosphatase and 5'-nucleotidase activity in the various stages of structural transformation.
journal_name
J Anatjournal_title
Journal of anatomyauthors
Kaur C,Ling EA,Wong WCsubject
Has Abstractpub_date
1987-10-01 00:00:00pages
215-27eissn
0021-8782issn
1469-7580journal_volume
154pub_type
杂志文章abstract：:In order to investigate further the effects of paralysis on skeletal development in the chick embryo, paralysis was induced at 6 days of incubation by dropping 0.2% solution of decamethonium bromide onto the chorioallantoic membrane and maintaining paralysis through to 20 days of incubation. General effects of paralys...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1991-08-01 00:00:00
abstract：:Two arteries connect the anterior branch of the middle meningeal artery to the lacrimal artery. One vessel, the sphenoidal artery, passes through the superior orbital fissure. The other vessel, the meningolacrimal artery, passes through the cranio-orbital foramen. An analysis of data derived from embryology, comparati...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1991-10-01 00:00:00
abstract：:The developing human brain can compensate for pre- and perinatally acquired focal lesions more effectively than the adult brain. The mechanisms by which this effective reorganization is achieved vary considerably between different functional systems, reflecting differences in the normal maturation of these systems. In...
journal_title：Journal of anatomy
pub_type： 杂志文章,评审
doi：10.1111/j.1469-7580.2010.01262.x
更新日期：2010-10-01 00:00:00
abstract：:Amoeboid microglial cells (AMC) in the corpus callosum were selectively labelled following a single intraperitoneal (i.p.) injection of the fluorescent dye, rhodamine isothiocyanate (RhIc) into postnatal rats. The frequency of RhIc-labelled cells varied with age, with the largest number occurring in 7-d-old animals. T...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1993-02-01 00:00:00
abstract：:The effects of bacterial lipopolysaccharide (LPS) on the expression of surface antigens including major histocompatibility complex (MHC) and complement type 3 (CR3) receptors on microglial cells in the corpus callosum in postnatal rat brain were investigated. When LPS was injected intravenously (i.v.) in 1-d-old rats,...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1994-04-01 00:00:00
abstract：:The histogenesis of the isocortical segment of the lateral telencephalic wall at the coronal level of the interventricular foramen was studied in mice between the ages of E10 and the adult. The proliferative activity of the periventricular germinal layers was correlated with changes in cell distributions in the interm...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1982-05-01 00:00:00
abstract：:Development of the neural crest involves a remarkable feat of coordinated cell migration in which cells detach from the neural tube, take varying routes of migration through the embryonic tissues and then differentiate at the end of their journey to participate in the formation of a number of organ systems. In general...
journal_title：Journal of anatomy
pub_type： 杂志文章,评审
doi：10.1046/j.1469-7580.1997.19140507.x
更新日期：1997-11-01 00:00:00
abstract：:Data are presented on the postnatal growth of the mouse bladder. Both bladder size (measured as surface area) and bladder wet weight increase steadily with age, respectively reaching 2.5 times and 4 times their newborn values by the age of ten weeks. Despite this growth, which may be due principally to non-urothelial ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1985-12-01 00:00:00
abstract：:The sensory and motor innervation of a sample of 202 muscle spindles from the dorsolateral tail muscles of eight cats were studied by silver and gold staining techniques. The range of diameters of Group Ia afferent nerve fibres to primary (P) sensory endings was 2.0-14.0 micron with a peak at 8.5 micron. The range of ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1984-03-01 00:00:00
abstract：:Extended aggregates of intracellular axonemal derivatives can be seen within the apical cytoplasm of ciliated cells of apparently healthy domestic pigs. Such alterations were observed in 15 out of 20 animals. Complete (9 + 2) or incomplete (8 + 2 - 5 + 2) intracellular axonemes were found which sometimes arose from ma...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1992-02-01 00:00:00
abstract：:As the uterus enlarges to accommodate the growing fetus during pregnancy, the cervix behaves essentially as a barrier. During ripening and delivery, it needs to become soft and distensible to allow dilation and the passage of the conceptus. As the transformations of the collagen-containing fibres are known to be essen...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1046/j.1469-7580.2003.00227.x
更新日期：2003-10-01 00:00:00
abstract：:Human beings stand upright with the chain of balance beginning at the feet, progressing to the lower limbs (ankles, knees, hip joints, pelvis), each of the spinal segments, and then ending at the cranium to achieve horizontal gaze and balance using minimum muscle activity. The details of the alignment and balance of t...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12586
更新日期：2017-05-01 00:00:00
abstract：:Pancreatic duct glands (PDGs) are tubule-alveolar glands associated with the pancreatic duct system and can be considered the anatomical counterpart of peribiliary glands (PBGs) found within the biliary tree. Recently, we demonstrated that endodermal precursor niches exist fetally and postnatally and are composed func...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12418
更新日期：2016-03-01 00:00:00
abstract：:Lateral cephalographs from 220 normal adolescent white orthodontic patients, and of individuals with craniofacial dysostosis and oculodento-osseous dysplasia were studied. Variations were observed in the morphology of the posterior margins of the superior articular processes, vertebral artery canals being present in 8...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1979-05-01 00:00:00
abstract：:A qualitative study by light and electron microscopy was undertaken on the liver of the brown trout, Salmo trutta fario. Vessels and bile ducts were observed to be scattered without any apparent order within the parenchyma. Venous profiles appeared either isolated or included in 'venous-arteriolar tracts' (VAT) and 'v...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1994-10-01 00:00:00
abstract：:Large perforations of the tympanic membrane were made in groups of guinea-pigs. The mitotic response in the stratified squamous epithelium at the edge of the wound was examined in perforations between 1 and 28 days after injury. Peaks of activity were discovered at 2, 15-16 and 24 days after wounding. It was also foun...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1977-12-01 00:00:00
abstract：:Internal cranial anatomy is a challenging area to study in fossilized skulls because of small sample sizes and varied post-mortem preservational alterations. This difficulty has led to the lack of correspondence between results obtained from direct osteological observation and from more indirect reconstruction methods...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2011.01427.x
更新日期：2011-12-01 00:00:00
abstract：:A vomeronasal organ and patent nasopalatine ducts were found in adult specimens of Aotus trivirgatus, Arctocebus calabarensis, Ateles geoffroyi and Saguinus fuscicollis. The vomeronasal complex appeared to be functional except in Ateles. However, the relative size of the organ in the Platyrrhini is much reduced compar...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1984-03-01 00:00:00
abstract：:The retinal vasculature of postmortem normal human and diabetic eyes was studied using an immunohistochemical technique in conjunction with confocal laser scanning microscopy. The technique, which stained for von Willebrand factor, allowed both large areas of the retinal vasculature to be visualised and abnormalities ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1046/j.1469-7580.1999.19410089.x
更新日期：1999-01-01 00:00:00
abstract：:A new type of magnetic resonance imaging analysis, based on fusion of three-dimensional reconstructions of time-to-peak parametric maps and high-resolution T1-weighted images, is proposed in order to evaluate the perfusion of selected volumes of interest. Because in recent years a wealth of data have suggested the cru...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2006.00659.x
更新日期：2007-01-01 00:00:00
abstract：:The gene for spondylo-metaphyseal chondrodysplasia (smc) in the mouse disrupts the formation of growth plate cartilage. No cartilage columns are found in the head of the tibia and secondary centres of ossification appear very late. The number of cells labelled with tritiated thymidine is sharply reduced at 16, 18 and ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1985-05-01 00:00:00
abstract：:The brain-derived neurotrophic factor (BDNF) gene is expressed in differentiating and post-mitotic neurons of the zebrafish embryo, where it has been implicated in Huntington's disease. Little is known, however, about the full complement of neuronal cell types that express BDNF in this important vertebrate model. Here...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12168
更新日期：2014-05-01 00:00:00
abstract：:The calcaneocuboid joint was studied in ligamentous specimens of ten human feet, and in skeletons of two gorillas (Gorilla gorilla beringei), six chimpanzees (Pan troglodytes), three orangutans (Pongo pygmaeus) and 25 human feet. The movement of the transverse tarsal joint was further studied in a living foot on a wal...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1979-08-01 00:00:00
abstract：:We have explored the innervation of the rainbow trout (O. mykiss) liver using immunohistochemical procedures and light microscopy to detect in situ protein gene product 9.5 and neuronal nitric oxide synthase immunoreactivities (PGP-IR and NOS-IR). The results showed PGP-IR nerve fibres running with the extralobular bi...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1046/j.1469-7580.1998.19320241.x
更新日期：1998-08-01 00:00:00
abstract：:Injury to the energy-storing superficial digital flexor tendon is common in equine athletes and is age-related. Tenocytes in the superficial digital flexor tendon of adult horses appear to have limited ability to respond adaptively to exercise or prevent the accumulation of strain-induced microdamage. It has been sugg...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2007.00781.x
更新日期：2007-09-01 00:00:00
abstract：:This paper reviews recent work in radiological image registration and provides a classification of image registration by type of transformation and by methods employed to compute the transformation. The former includes transformation of 2D images to 2D images of the same individual, transformation of 3D images to 3D i...
journal_title：Journal of anatomy
pub_type： 杂志文章,评审
doi：10.1046/j.1469-7580.1998.19330347.x
更新日期：1998-10-01 00:00:00
abstract：:We present a simple and quick system for accurately scoring the developmental progress of mouse embryos harvested on embryonic day 14 (E14.5). Based solely on the external appearance of the maturing forelimb, we provide a convenient way to distinguish six developmental sub-stages. Using a variety of objective morphome...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12590
更新日期：2017-05-01 00:00:00
abstract：:The dogma that cutaneous wound healing is impaired as a function of age is largely unsubstantiated. This can be attributed to poor experimental design of human studies, the lack of subject characterisation with the exclusion of disease processes, and the study of inappropriate animal models. Structural and functional ...
journal_title：Journal of anatomy
pub_type： 杂志文章,评审
doi：
更新日期：1995-08-01 00:00:00
abstract：:This study analyses the evaluation of tomographic indicators of tibia structure, assuming that the usual loading pattern shifts from uniaxial compression close to the heel to a combined compression, torsion and bending scheme towards the knee. To this end, pQCT scans were obtained at 5% intervals of the tibia length (...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2009.01201.x
更新日期：2010-04-01 00:00:00
abstract：:Integrating microdensitometry was used to study changes in the intracellular activity of 4 enzymes during macrophage development. Suspension cultures of blood monocytes from 19 healthy human subjects were examined at 0, 2, 4 and 6 d. Mononuclear phagocytes were harvested by glass adherence and standard methods were us...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1993-08-01 00:00:00
