Abstract:
:Development of the neural crest involves a remarkable feat of coordinated cell migration in which cells detach from the neural tube, take varying routes of migration through the embryonic tissues and then differentiate at the end of their journey to participate in the formation of a number of organ systems. In general, neural crest cells appear to migrate without the guidance of long-range physical or chemical cues, but rather they respond to heterogeneity in the extracellular matrix that forms their migration substrate. Molecules such as fibronectin and laminin act as permissive substrate components, encouraging neural crest cell attachment and spreading, whereas chondroitin sulphate proteoglycans are nonpermissive for migration. A balance between permissive and nonpermissive substrate components seems to be necessary to ensure successful migration, as indicated by a number of studies in mouse mutant systems where nonpermissive molecules are over-expressed, leading to inhibition of neural crest migration. The neural crest expresses cell surface receptors that permit interaction with the extracellular matrix and may also modify the matrix by secretion of proteases. Thus the principles that govern the complex migration of neural crest cells are beginning to emerge.
journal_name
J Anatjournal_title
Journal of anatomyauthors
Henderson DJ,Copp AJdoi
10.1046/j.1469-7580.1997.19140507.xsubject
Has Abstractpub_date
1997-11-01 00:00:00pages
507-15eissn
0021-8782issn
1469-7580journal_volume
191 ( Pt 4)pub_type
杂志文章,评审abstract::The ventricle of the salmonid heart consists of an outer compact layer of circumferentially arranged cardiomyocytes encasing a spongy myocardium that spans the lumen of the ventricle with a fine arrangement of muscular trabeculae. While many studies have detailed the anatomical structure of fish hearts, few have consi...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2009.01129.x
更新日期:2009-11-01 00:00:00
abstract::The aims of the present study were to determine whether nerves that contain nitric oxide synthase (NOS), calcitonin gene-related peptide (CGRP) or substance P (SP) are present in the human vagina and, if so, to determine the pattern of innervation relative to that of other neurotransmitters, particularly vasoactive in...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1996-06-01 00:00:00
abstract::The aim of this study was to design, develop and employ a method for the acquisition of a significant data base of thickness measurements. The integration of standard histological techniques (step serial sectioning), modern computer technology and a personally developed software package (specifically designed for thic...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1991-10-01 00:00:00
abstract::The histochemical and ultrastructural characteristics of the adult rat and rabbit costal diaphragm were investigated. On the basis of enzyme histochemistry, the rat diaphragm was found to contain 42% and 39% Type I, 24% and 25% Type II A and 33% and 34% Type II B fibres on the thoracic and abdominal surfaces respectiv...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1990-02-01 00:00:00
abstract::Decline of tactile sensation associated with ageing depends on modifications in skin and both central and peripheral nervous systems. At present, age-related changes in the periphery of the somatosensory system, particularly concerning the effects on mechanoreceptors, remain unknown. Here we used immunohistochemistry ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12983
更新日期:2019-06-01 00:00:00
abstract::Bundles of collagen fibrils, elastic fibres and fibroblasts are organized into a network that lies in the plane of a large portion of the bat wing. By ultrastructural (TEM and SEM) and biochemical analyses it was found that individual bundles of the net are similar to elastic ligaments. Although elastic fibres predomi...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1978-05-01 00:00:00
abstract::The development of the olfactory epithelium from the 10th day of gestation of postnatal life has been examined electron miscroscopically in the mouse. At 10 days' gestation the epithelium is already differentiated into dark and pale cells, the former representing embryonic stem cells and the latter the developing rece...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1975-07-01 00:00:00
abstract::Apoptosis is an essential physiological process in embryonic development. In the developing eye of vertebrates, three periods of developmental apoptosis can be distinguished: early, intermediate and later. Within the apoptosis pathway, caspases play a crucial role. It has also been shown that HSP110 may have a potenti...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2007.00719.x
更新日期:2007-05-01 00:00:00
abstract::Experimental evidence indicates that lymph nodes in humans undergo alterations during ageing. This is clinically important because of the crucial role of these organs in the immune system and their lymph reabsorption and drainage function. Although some age-related changes in lymph node histoarchitecture have been des...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2010.01213.x
更新日期:2010-05-01 00:00:00
abstract::Little is known about the embryonic development and variation of the chondrocranium in Crocodylia and there are no works on any Caiman species. Due to the importance of cranial features in the systematics of this clade, investigating the development of the skull in embryonic stages is essential. In this study, we pres...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12968
更新日期:2019-06-01 00:00:00
abstract::Some aspects of normal obliteration of sutures in rabbit and man were studied histologically and it was found that suture closure took place by intramembranous ossification in specific areas of trans-suturally arranged, tendon-like tissue. Histochemically these areas demonstrated high activity of oxidative enzymes. ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1978-02-01 00:00:00
abstract::This paper reviews recent work in radiological image registration and provides a classification of image registration by type of transformation and by methods employed to compute the transformation. The former includes transformation of 2D images to 2D images of the same individual, transformation of 3D images to 3D i...
journal_title:Journal of anatomy
pub_type: 杂志文章,评审
doi:10.1046/j.1469-7580.1998.19330347.x
更新日期:1998-10-01 00:00:00
abstract::A one day symposium of the Anatomical Society of Great Britain and Ireland was held at the Royal Free Hospital in London on the 17th September 1999, on the topic of 'Mechanisms of ageing and longevity'. The following are abstracts of communications and posters presented at the meeting. ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.2000.19620293.x
更新日期:2000-02-01 00:00:00
abstract::The distribution of muscle fibres classified on the basis of their content of different myosin heavy chain (MHC) isoforms was analysed in vastus lateralis muscle biopsies of 15 young men (with an average age of 22 y) by correlating immunohistochemistry with specific anti-MHC monoclonal antibodies, myofibrillar ATPase ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.2001.19930329.x
更新日期:2001-09-01 00:00:00
abstract::In zoology it is well known that birds are characterized by the presence of feathers, and mammals by hairs. Another common point of view is that avian scales are directly related to reptilian scales. As a skin embryologist, I have been fascinated by the problem of regionalization of skin appendages in amniotes through...
journal_title:Journal of anatomy
pub_type: 杂志文章,评审
doi:10.1111/j.1469-7580.2008.01041.x
更新日期:2009-04-01 00:00:00
abstract::Cellullar deficits are replenished within the central nervous system (CNS) by progenitors to maintain integrity and recover function after injury. NG2 proteoglycan-expressing progenitors replenish oligodendrocyte populations, but the nature of NG2 proteoglycan may not indicate a restricted population of progenitors. A...
journal_title:Journal of anatomy
pub_type: 杂志文章,评审
doi:10.1111/j.1469-7580.2005.00480.x
更新日期:2005-12-01 00:00:00
abstract::These studies, on a variety of laboratory, zoo and agricultural animals, show that the phenomenon of replacement of tissues lost in an ear punch is common to some other mammals as well as the rabbit, although the rabbit appears to be the most proficient in this process. It is suggested that the cartilage may be replac...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1986-12-01 00:00:00
abstract::The sacroiliac joint (SIJ) is a well-known source of low back and pelvic pain, of increasing interest for both conservative and surgical treatment. Alterations in the kinematics of the pelvis have been hypothesized as a major cause of SIJ-related pain. However, definitions of both the range and the extent of physiolog...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12924
更新日期:2019-03-01 00:00:00
abstract::A defining feature of dentitions in modern sharks and rays is the regulated pattern order that generates multiple replacement teeth. These are arranged in labio-lingual files of replacement teeth that form in sequential time order both along the jaw and within successively initiated teeth in a deep dental lamina. Two ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12796
更新日期:2018-06-01 00:00:00
abstract::The architecture of the fibres in the sciatic nerve of the dog has been analysed by following the degeneration of fibres resulting from division of the individual spinal nerves which contribute to the sciatic nerve. A pattern has been demonstrated which varies in part with the size of the contribution to the sciatic n...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1978-10-01 00:00:00
abstract::This study describes the degenerative changes of the axon terminals making synaptic contacts with the neurons in the submucous ganglia of guinea pig small and large intestines following left or right cervical vagotomy. There were no noticeable ultrastructural changes 1 d after the operation. Beginning at the 3rd posto...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1995-12-01 00:00:00
abstract::A quantitative and morphological study was made of the corpus callosum in children to assess possible sex differences. The shape of the splenium of the corpus callosum was observed to vary between bulbous and cylindrical types with respect to the body of the callosum. The variation was not gender-specific and covariat...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1985-12-01 00:00:00
abstract::Muscle moment arms were measured for major muscles of the pelvic limb of the ostrich (Struthio camelus) in order to assess specific functional behaviour and to apply this to locomotor performance. Pelvic limbs of six juvenile ostriches were used for this study. The tendon travel technique was used to measure moment ar...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2007.00762.x
更新日期:2007-09-01 00:00:00
abstract::The olfactory bulb of adult specimens of Carassius auratus was subjected to an autoradiographic study using [3H]thymidine. Adult specimens of Carassius auratus, Barbus meridionalis, Cyprinus carpio and Salmo gairdneri were also studied using light and electron microscopy. Cells were found undergoing mitotic division w...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1989-04-01 00:00:00
abstract::The absolute density of the right and left os calcis has been measured in a group of healthy, sedentary volunteers. There was a significant difference between the density of the right and left os calcis in 90% of the subjects. Statistically, when all of the subjects were considered, the side on which the os calcis was...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1976-02-01 00:00:00
abstract::The quantitative assessment of the lung architecture forms the foundation of many studies on lung development and lung diseases, where parameters such as alveoli number, alveolar size, and septal thickness are quantitatively influenced by developmental or pathological processes. Given the pressing need for robust data...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12773
更新日期:2018-03-01 00:00:00
abstract::We previously identified a pericellular matrix keratan sulphate/chondroitin sulphate proteoglycan present on the surface of human embryonal carcinoma stem cells, cells whose differentiation mimics early development. Antibodies reactive with various epitopes on this molecule define a cluster of differentiation markers ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.2002.00034.x
更新日期:2002-03-01 00:00:00
abstract::Histochemical fibre types classified in sections stained for succinic dehydrogenase (sdh) and myosin ATPase at pH 9.4, were found to be distributed in a consistent manner within the extensor digitorum longus (EDL) and 4 soleus muscles of the adult rat. Simple morphometric techniques applied to complete transverse sect...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1977-04-01 00:00:00
abstract::It is a challenge to understand how barn owls (Tyto alba) reduce noise during flight to be able to hunt small mammals by audition. Several specializations of the wing and the wing feathers have been implicated in noise reduction. What has been overlooked so far are the fringes at the inner vanes of remiges. We demonst...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2012.01504.x
更新日期:2012-07-01 00:00:00
abstract::Retrograde fluorescent transport of Fast Blue (FB) and Diamidino Yellow (DY) was used to study the localisation of neurons that innervate the palpebral conjunctiva and the superior tarsal muscle in the cynomolgous monkey. Labelled cell bodies of sensory neurons including a few double labelled cell bodies were found in...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1996-10-01 00:00:00