Abstract:
:A new type of magnetic resonance imaging analysis, based on fusion of three-dimensional reconstructions of time-to-peak parametric maps and high-resolution T1-weighted images, is proposed in order to evaluate the perfusion of selected volumes of interest. Because in recent years a wealth of data have suggested the crucial involvement of vascular alterations in mental diseases, we tested our new method on a restricted sample of schizophrenic patients and matched healthy controls. The perfusion of the whole brain was compared with that of the caudate nucleus by means of intrasubject analysis. As expected, owing to the encephalic vascular pattern, a significantly lower time-to-peak was observed in the caudate nucleus than in the whole brain in all healthy controls, indicating that the suggested method has enough sensitivity to detect subtle perfusion changes even in small volumes of interest. Interestingly, a less uniform pattern was observed in the schizophrenic patients. The latter finding needs to be replicated in an adequate number of subjects. In summary, the three-dimensional analysis method we propose has been shown to be a feasible tool for revealing subtle vascular changes both in normal subjects and in pathological conditions.
journal_name
J Anatjournal_title
Journal of anatomyauthors
Fabene PF,Farace P,Brambilla P,Andreone N,Cerini R,Pelizza L,Versace A,Rambaldelli G,Birbaumer N,Tansella M,Sbarbati Adoi
10.1111/j.1469-7580.2006.00659.xsubject
Has Abstractpub_date
2007-01-01 00:00:00pages
122-8issue
1eissn
0021-8782issn
1469-7580pii
JOA659journal_volume
210pub_type
杂志文章abstract::Early hominins formed large and thick-enamelled cheek-teeth within relatively short growth periods as compared with modern humans. To understand better the developmental basis of this process, we measured daily enamel increments, or cross striations, in 17 molars of Plio-Pleistocene hominins representing seven differe...
journal_title:Journal of anatomy
pub_type: 历史文章,杂志文章
doi:10.1111/j.1469-7580.2008.00938.x
更新日期:2008-08-01 00:00:00
abstract::Pancreatic duct glands (PDGs) are tubule-alveolar glands associated with the pancreatic duct system and can be considered the anatomical counterpart of peribiliary glands (PBGs) found within the biliary tree. Recently, we demonstrated that endodermal precursor niches exist fetally and postnatally and are composed func...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12418
更新日期:2016-03-01 00:00:00
abstract::Collagen fibrils from different rat tendons have been investigated by freeze-fracture and transmission electron microscopy. In all cases, marked differences in both fibril morphology and subfibrillar organisation have been consistently found between the tendon core (composed of large and heterogeneous fibrils comprisi...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1990-10-01 00:00:00
abstract::Differences are reported in the total calcified tissue/bone marrow ratios and in the total thickness of cortical calcified tissue (lamellar bone and calcified fibrocartilage) between the attachment sites of the quadriceps tendon and the patellar ligament in man. The greatest amount of calcified tissue is at the insert...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1991-02-01 00:00:00
abstract::Retrograde tracers were injected in various parts of the neocortex of the porpoise (Phocoena phocoena). Labelled thalamic neurons were plotted in three-dimensional reconstructions. The lateral geniculate nucleus projects to the visually excitable part of the lateral gyrus. Ventral parts of the medial geniculate nucleu...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1990-04-01 00:00:00
abstract::Two arteries connect the anterior branch of the middle meningeal artery to the lacrimal artery. One vessel, the sphenoidal artery, passes through the superior orbital fissure. The other vessel, the meningolacrimal artery, passes through the cranio-orbital foramen. An analysis of data derived from embryology, comparati...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1991-10-01 00:00:00
abstract::The surface coating of the alveolar macrophages and pneumonocytes of hamster lung was studied using an electron microscopy technique. Slices of lung tissue were fixed in aldehyde, labelled with a battery of lectin-horseradish peroxidase conjugates, incubated in a diaminobenzidine-hydrogen peroxide medium and then post...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1986-06-01 00:00:00
abstract::The effects of bacterial lipopolysaccharide (LPS) on the expression of surface antigens including major histocompatibility complex (MHC) and complement type 3 (CR3) receptors on microglial cells in the corpus callosum in postnatal rat brain were investigated. When LPS was injected intravenously (i.v.) in 1-d-old rats,...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1994-04-01 00:00:00
abstract::Mucins are high molecular weight glycoproteins which constitute the major component of the mucus layer and are produce by many epithelial tissues in vertebrates. Osteopontin (OPN) is an adhesive phosphorylated glycoprotein that is expressed by a broad range of tissues and cells. Although gastric mucins MUC1, MUC5AC, M...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2010.01243.x
更新日期:2010-07-01 00:00:00
abstract::M. semitendinosus and m. trapezius (portion) were removed from eight miniature pigs ranging from 21 to 160 days of age and eight age-control as well as eight weight-control commercial Large White pigs. Complete transverse frozen sections were obtained for each muscle sample and stained for various enzyme activities in...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1986-08-01 00:00:00
abstract::Many studies have demonstrated the association between facet tropism and disc herniation in the lumbar spine. Some of them found that lumbar disc herniation was on the side of the more sagittal facet joint interface. However, little is understood about the association of facet tropism with disc herniation in the cervi...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.13151
更新日期:2020-05-01 00:00:00
abstract::This study was prompted by the prospect of transgenic pigs providing donor hearts for transplantation in human recipients. Autonomic innervation is important for the control of cardiac dynamics, especially in the conduction system. Our objective was to assess the relative distribution of autonomic nerves in the pig he...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.1999.19530341.x
更新日期:1999-10-01 00:00:00
abstract::The present study investigated, by immunohistochemistry, the postnatal occurrence and anatomical localisation of some bone and cartilage proteins and proteoglycans in the rat coronal sutural region. Thirty two Sprague-Dawley rats, four in each group, were killed at ages 3, 5, 8, 10, 15, 30, 50 and 100 days and the sut...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1990-12-01 00:00:00
abstract::Lactating animals are particularly susceptible to mastitis during the early stages of mammary gland involution following weaning. In this study we compared the phagocytic capacity of cells collected from sheep mammary secretions at different stages of involution. The ability of neutrophils and macrophages to ingest la...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.0021-8782.2002.00104.x
更新日期:2002-11-01 00:00:00
abstract::Since their discovery in different human tissues by Zimmermann in 1898, primary cilia have been found in the vast majority of cell types in vertebrates. Primary cilia are considered to be cellular antennae that occupy an ideal cellular location for the interpretation of information both from the environment and from o...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12360
更新日期:2015-10-01 00:00:00
abstract::Facial size reduction and facial retraction are key features that distinguish modern humans from archaic Homo. In order to more fully understand the emergence of modern human craniofacial form, it is necessary to understand the underlying evolutionary basis for these defining characteristics. Although it is well estab...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2009.01162.x
更新日期:2010-01-01 00:00:00
abstract::It is known that removal of one eye in the rat in early postnatal life results in an aberrant ipsilateral projection from the remaining eye. We have estimated the number of optic nerve fibres in 36 days old Black and White Hooded rats that had been unilaterally enucleated at birth. There was no significant difference ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1991-02-01 00:00:00
abstract::Primates have shoulders adapted to a wide range of locomotor functions from terrestrial pronograde quadrupedalism to highly arboreal suspensory behaviours. The shape of the scapula tightly follows these functional differences. Previous analyses of primate postcrania, including the scapula, indicate that quadrupedal mo...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2006.00639.x
更新日期:2006-11-01 00:00:00
abstract::Cetaceans face the challenge of maintaining equilibrium underwater and obtaining sensory input within a dense, low-visibility medium. The cetacean ear represents a key innovation that marked their evolution from terrestrial artiodactyls to among the most fully aquatic mammals in existence. Using micro-CT and histologi...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12548
更新日期:2017-02-01 00:00:00
abstract::The process of anatomical ductal obliteration appears to be gradual and to involve proliferation of intima and media (mainly the latter) producing mounds, mucoid-filled spaces and fragmentation of the internal elastic membrane. Dissociation of the inner media may also be involved. The persistent ductus can be recogniz...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1979-06-01 00:00:00
abstract::The study of the underlying mechanisms by which cells respond to mechanical stimuli, i.e. the link between the mechanical stimulus and gene expression, represents a new and important area in the morphological sciences. Several cell types ('mechanocytes'), e.g. osteoblasts and fibroblasts as well as smooth, cardiac and...
journal_title:Journal of anatomy
pub_type: 杂志文章,评审
doi:10.1046/j.1469-7580.1999.19430323.x
更新日期:1999-04-01 00:00:00
abstract::The endoskeleton of elasmobranchs (sharks and rays) is comprised largely of unmineralized cartilage, differing fundamentally from the bony skeletons of other vertebrates. Elasmobranch skeletons are further distinguished by a tessellated surface mineralization, a layer of minute, polygonal, mineralized tiles called tes...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12508
更新日期:2016-11-01 00:00:00
abstract::Rodents, together with bats, are among the ecologically most diverse and most speciose groups of mammals. Moreover, rodents show elaborate specializations of the feeding apparatus in response to the predominantly fore-aft movements of the lower jaw. The Laotian rock rat Laonastes aenigmamus was recently discovered and...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2012.01519.x
更新日期:2012-08-01 00:00:00
abstract::The rete testis in the domestic fowl (Gallus gallus domesticus), Japanese quail (Coturnix coturnix japonica), guinea-fowl (Numida meleagris galeata) and drake (Anas platyrhynchos) was studied histologically and with both the scanning and transmission electron microscopes. All the birds have rete epithelial cells varyi...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1982-08-01 00:00:00
abstract::The Harderian gland, its secretory duct and porphyrin content were examined in the mongolian gerbil (Meriones unguiculatus). The gland consisted of tubules lined by a single layer of epithelial cells and a myoepithelial network. The tubule cells were often binucleate and possessed lipid vacuoles in the apical half of ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1983-10-01 00:00:00
abstract::The anatomy of porcine bronchial circulation has not been fully described. The purpose of this study was to investigate the extrapulmonary topographic anatomy of bronchial arteries in pig. Ten pigs weighing 15-25 kg were studied. Between one and four bronchial arteries were found in each pig. The bronchoesophageal art...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2005.00455.x
更新日期:2005-10-01 00:00:00
abstract::The posterior orbitofrontal cortex, anterior temporal sensory association areas and the amygdala have a key role in emotional processing and are robustly interconnected. By analogy with the pattern of connections in early processing sensory areas, anterior temporal sensory and polymodal association cortices send prima...
journal_title:Journal of anatomy
pub_type: 杂志文章,评审
doi:10.1111/j.1469-7580.2007.00777.x
更新日期:2007-08-01 00:00:00
abstract::The vomeronasal system (VNS) has been extensively studied within specific animal families, such as Rodentia. However, the study of the VNS in other families, such as Canidae, has long been neglected. Among canids, the vomeronasal organ (VNO) has only been studied in detail in the dog, and no studies have examined the ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.13254
更新日期:2020-11-01 00:00:00
abstract::The glycan composition of the N- and O-linked oligosaccharides of the follicle (Sertoli) cells of the urodele amphibian Pleurodeles waltl testis were identified by lectin histochemistry, performed alone or in combination with enzymatic and chemical deglycosylation methods. The follicle cells were shown to contain: (1)...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.2001.19860673.x
更新日期:2001-06-01 00:00:00
abstract::The histochemical and ultrastructural characteristics of the adult rat and rabbit costal diaphragm were investigated. On the basis of enzyme histochemistry, the rat diaphragm was found to contain 42% and 39% Type I, 24% and 25% Type II A and 33% and 34% Type II B fibres on the thoracic and abdominal surfaces respectiv...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1990-02-01 00:00:00