Abstract：
:Germline stem cells, which can self-renew and generate gametes, are unique stem cells in that they are solely dedicated to transmit genetic information from generation to generation. The germ cells have a special place in the life cycle because they must be able to retain the ability to recreate the organism, a property known as developmental totipotency. Several lines of evidence have suggested the extensive proliferation activity and pluripotency of prenatal, neonatal and adult germline stem cells. We showed that adult male germline stem cells, spermatogonial stem cells, can be converted into embryonic stem cell-like cells, which can differentiate into the somatic stem cells of three germ layers. Different cell types such as vascular, heart, liver, pancreatic and blood cells could also be obtained from these stem cells. Understanding how spermatogonial stem cells can give rise to pluripotent stem cells and how somatic stem cells differentiate into germ cells could give significant insight into the regulation of developmental totipotency as well as having important implications for male fertility and regenerative medicine.
journal_name
J Anatjournal_title
Journal of anatomyauthors
Mardanpour P,Guan K,Nolte J,Lee JH,Hasenfuss G,Engel W,Nayernia Kdoi
10.1111/j.1469-7580.2008.00930.xsubject
Has Abstractpub_date
2008-07-01 00:00:00pages
26-9issue
1eissn
0021-8782issn
1469-7580pii
JOA930journal_volume
213pub_type
杂志文章,评审abstract：:Facial expressions are a critical mode of non-vocal communication for many mammals, particularly non-human primates. Although chimpanzees (Pan troglodytes) have an elaborate repertoire of facial signals, little is known about the facial expression (i.e. mimetic) musculature underlying these movements, especially when ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2006.00523.x
更新日期：2006-02-01 00:00:00
abstract：:Literature on the development of the human vagina is abundant; however, contributions concerning the prenatal development of the entire utero-vaginal anlagen (UVA) are rare or carried out in rodents. The primary epithelial characteristics in the adult vagina and uterus are determined during prenatal development and de...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12029
更新日期：2013-04-01 00:00:00
abstract：:A study has been made of the distribution of granulated metrial gland cells in the non-pregnant uterus, in the pre-implantation uterus and in the post-implantation interconceptual uterus of pregnant albino mice. Granulated cells were only rarely seen in the non-pregnant uterus. In the pre-implantation uterus, they wer...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1981-12-01 00:00:00
abstract：:Three modes of construction of the rectus sheath above the arcuate line were found in a study of 40 cadavers. The classical description occurred most frequently, in 24 cases. The other constructions conformed to those described in earlier studies although the incidences were different. The accessory internal oblique m...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1986-04-01 00:00:00
abstract：:A vomeronasal organ and patent nasopalatine ducts were found in adult specimens of Aotus trivirgatus, Arctocebus calabarensis, Ateles geoffroyi and Saguinus fuscicollis. The vomeronasal complex appeared to be functional except in Ateles. However, the relative size of the organ in the Platyrrhini is much reduced compar...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1984-03-01 00:00:00
abstract：:The structure of the sinuatrial nodal artery has been investigated in young and old rats. The nodal artery is derived from the internal thoracic artery, runs centrally though the node and supplies it by several branches. An extensive cuff of nodal cells is seen within the adventitia of the artery and its branches adja...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1980-06-01 00:00:00
abstract：:Bundles of collagen fibrils, elastic fibres and fibroblasts are organized into a network that lies in the plane of a large portion of the bat wing. By ultrastructural (TEM and SEM) and biochemical analyses it was found that individual bundles of the net are similar to elastic ligaments. Although elastic fibres predomi...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1978-05-01 00:00:00
abstract：:Glycosaminoglycans have been demonstrated throughout the cutaneous BMZ at the ultrastructural level. Colloidal iron and cationised ferritin proved of limited value, whilst staining with Alcian blue and application of the critical electrolyte concentration principle has provided evidence for the presence of sulphated G...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1991-06-01 00:00:00
abstract：:An immuno-epifluorescence microscopic study of first trimester human chorionic villi has revealed different patterns of distribution for intermediate filament proteins. Keratin staining was restricted to the trophoblastic epithelium. The protein was shown to be concentrated into desmosome-containing apical and basal c...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1990-04-01 00:00:00
abstract：:This paper reviews recent work in radiological image registration and provides a classification of image registration by type of transformation and by methods employed to compute the transformation. The former includes transformation of 2D images to 2D images of the same individual, transformation of 3D images to 3D i...
journal_title：Journal of anatomy
pub_type： 杂志文章,评审
doi：10.1046/j.1469-7580.1998.19330347.x
更新日期：1998-10-01 00:00:00
abstract：:The present paper reports the results of the first investigation of the semicircular canals in a living, small animal by means of high spatial resolution magnetic resonance imaging. This procedure is noninvasive and allows identification of the endolymphatic and perilymphatic spaces yielding a morphology quite consist...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1992-04-01 00:00:00
abstract：:Neural stem cells are a multipotent population of tissue-specific stem cells with a broad but limited differentiation potential. However, recent studies have shown that over-expression of the pluripotency gene, Oct4, alone is sufficient to initiate a process by which these can form 'induced pluripotent stem cells' (iP...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2010.01269.x
更新日期：2010-09-01 00:00:00
abstract：:As the uterus enlarges to accommodate the growing fetus during pregnancy, the cervix behaves essentially as a barrier. During ripening and delivery, it needs to become soft and distensible to allow dilation and the passage of the conceptus. As the transformations of the collagen-containing fibres are known to be essen...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1046/j.1469-7580.2003.00227.x
更新日期：2003-10-01 00:00:00
abstract：:Cardiac arrhythmias, notably Wolff-Parkinson-White syndrome, are known to represent a major issue in patients with Ebstein's malformation of the tricuspid valve. Abnormal conducting circuits, however, can also be produced by pathways extending either from the atrioventricular node or the ventricular components of the ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.13179
更新日期：2020-07-01 00:00:00
abstract：:The fine structure of the elastic cartilage of the pinna has been examined in young rabbits aged from 1 day to 1108 days. Changes associated with growth and development are related not only to age but also to the actual situation in the pinna. In the midline, progressive changes are seen from the tip to the base. The ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1977-04-01 00:00:00
abstract：:The canine's olfactory acuity is legendary, but neither its main olfactory system nor its vomeronasal system has been described in much detail. We used immunohistochemistry on paraffin-embedded sections of male and female adult dog vomeronasal organ (VNO) to characterize the expression of proteins known to be expresse...
journal_title：Journal of anatomy
pub_type： 更正并重新发布的文章,杂志文章
doi：
更新日期：2003-09-01 00:00:00
abstract：:Anatomical specimens used in human or veterinary anatomy laboratories are usually prepared with formaldehyde (a cancerous and teratogenic substance), glycerin (an expensive and viscous fluid), or ethanol (which is flammable). This research aimed to verify the viability of an aqueous 30% sodium chloride solution for pr...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12185
更新日期：2014-07-01 00:00:00
abstract：:At the tip of the lower beak of the chicken there were found 15-20 specialised dermal papillae containing large numbers of mechanoreceptors. The Merkel or Grandry corpuscles were situated distally in the papillae and at the papillae base was a collection of Herbst corpuscles. The apex of the papillae, under the scanni...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1986-04-01 00:00:00
abstract：:There is an accumulating body of evidence that highlights the fact that one can identify convergence in programmes of cellular differentiation. That is, that a particular differentiated cell/tissue type can be generated via non-identical paths. Convergence is also seen in evolution and here it is termed homoplasy, thu...
journal_title：Journal of anatomy
pub_type： 杂志文章,评审
doi：10.1111/j.1469-7580.2010.01232.x
更新日期：2010-06-01 00:00:00
abstract：:Vascular sympathetic neuroeffector associations have been examined in rat iris arterioles using serial section electron microscopy and reconstruction techniques. Examination of random sections showed that, of all profiles of varicosities (199) seen to lie closer than 4 microns to vascular smooth muscle cells, only a s...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1046/j.1469-7580.1998.19210045.x
更新日期：1998-01-01 00:00:00
abstract：:The entire head and neck of a wild adult male Mongolian gazelle (Procapra gutturosa) was dissected with special reference to its enlarged larynx. Two additional adult male specimens taken from the wild were analysed by computer tomography. The sternomandibularis, omohyoideus, thyrohyoideus and hyoepiglotticus muscles ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1046/j.1469-7580.2003.00232.x
更新日期：2003-11-01 00:00:00
abstract：:The morphological transition from the simple epidermis that contacts the amniotic fluid of embryonic crocodilians to the adult epidermis required in a terrestrial environment has never been described. We used light and electron microscopy to study the development, differentiation and keratinisation of the epidermis of...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1046/j.1469-7580.2001.19830265.x
更新日期：2001-03-01 00:00:00
abstract：:The fossil record supports the conclusions derived from the study of extant species that the Primates evolved a unique suite of characters in the articulations of the foot. The tarsal bones of African Miocene apes show specializations characteristic of hominoid evolution and provide reasonable precursors for the morph...
journal_title：Journal of anatomy
pub_type： 历史文章,杂志文章
doi：
更新日期：1980-09-01 00:00:00
abstract：:Two endocrine cell types were found in the metaplastic epithelium of gall bladders removed for gall stones. The endocrine cell type I resembled the EC (enterochromaffin) cell of the normal stomach mucosa. The homogeneous and electron-dense secretory granules were variable in size and shape and mainly located in the su...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1975-11-01 00:00:00
abstract：:Quantitative measurements of relative nerve density were achieved using computer-assisted image analysis of immunohistochemically and histochemically defined nerves in the conduction system of the guinea pig heart. All regions of the conduction system possessed a similar density of nerve fibres and fascicles displayin...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1996-04-01 00:00:00
abstract：:This investigation is based upon the pineal organs of 92 specimens of 36 species of the family Pteropodidae (Mammalia, Chiroptera). The size of the megachiropteran pineal correlates well with body size (r = 0.864), confirming the former conclusions that generally larger bodied bats have larger pineals. The range of th...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1990-02-01 00:00:00
abstract：:In an attempt to clarify the nature of the human cemento-dentinal junction, ground sections of incompletely formed and fully formed extracted teeth were prepared and their histology compared with their microradiographic appearances. The results showed that incompletely formed teeth possess distinctive surface layers o...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1976-11-01 00:00:00
abstract：:Collagen fibrils from different rat tendons have been investigated by freeze-fracture and transmission electron microscopy. In all cases, marked differences in both fibril morphology and subfibrillar organisation have been consistently found between the tendon core (composed of large and heterogeneous fibrils comprisi...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1990-10-01 00:00:00
abstract：:The Harderian gland, its secretory duct and porphyrin content were examined in the mongolian gerbil (Meriones unguiculatus). The gland consisted of tubules lined by a single layer of epithelial cells and a myoepithelial network. The tubule cells were often binucleate and possessed lipid vacuoles in the apical half of ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1983-10-01 00:00:00
abstract：:Although laryngeal morphology often reflects adaptations for vocalization, the structural consequences of selection for particular aspects of vocal behavior remain poorly understood. In this study, we investigated the effects of increased ultrasonic calling in pups on the adult larynx morphology in selectively bred ra...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.13366
更新日期：2021-01-21 00:00:00
