Abstract:
:The present report describes quantitative studies of mitochondria from stratified squamous epithelial cells from hamster cheek pouch mucosa in differentiating compartments. Mucosa was processed for electron microscopy and, using strict sampling procedures, electron micrographs of epithelium from defined basal, spinous and granular strata were acquired. Using stereological and other morphometric methods, the volume density, numerical density and volume-to-surface ratio of mitochondria were estimated in each cellular layer, and these data were transformed into absolute values characterising the average cell in these layers. The results suggest that both volumetric and numerical densities of mitochondria decreased progressively during epithelial differentiation; conversely, the total volume and number of mitochondria present in granular cells were consistently higher than in basal cells, as was the volume of individual mitochondria. These quantitative changes may reflect functional alterations in the metabolism of epithelial cells during differentiation and provide a base line for further work on experimental epithelial biology and pathology.
journal_name
J Anatjournal_title
Journal of anatomyauthors
White FH,Gohari Ksubject
Has Abstractpub_date
1983-06-01 00:00:00pages
801-19issue
Pt 4eissn
0021-8782issn
1469-7580journal_volume
136pub_type
杂志文章abstract::The structure of amniotic papillae in sheep was investigated by light transmission and scanning electron microscopy. Papillae were found on the amnion near the umbilical cord in a majority of the sheep examined, from early mid-term onwards. The papillae possessed a basic connective tissue core with a varying degree of...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1978-06-01 00:00:00
abstract::Peripheral sensory and autonomic neurons are known to possess insulin receptors. These have been considered to be of the peripheral type, i.e. similar to those of hepatic and fat cells rather than of the brain type which show dual specificity for both insulin and insulin-like growth factor (IGF-1). We have examined th...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.1997.19130431.x
更新日期:1997-10-01 00:00:00
abstract::The translocation of mitochondria towards the primitive inner segment of the cones in the tree shrew Tupaia belangeri was investigated by transmission electron microscopy. Throughout ontogeny the migrating mitochondria were codistributed with cytoplasmic microtubules which were preserved after the application of conve...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1996-10-01 00:00:00
abstract::A quantitative analysis of the motor innervation of intrafusal muscle fibres is described, based on teased silver-impregnated spindles of the tenuissimus muscle of the cat. Included in the analysis are the number and distribution of intrafusal branches of both skeletofusimotor (beta) and purely fusimotor (gamma) axons...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1994-08-01 00:00:00
abstract::Previous quantitative descriptions of cellular ultrastructure have focused on spatial content (volume, surface area and number of organelles and membrane domains). It is possible to complement such descriptions by also quantifying spatial arrangements. Hitherto, applications of stereological methods for achieving this...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.1999.19420279.x
更新日期:1999-02-01 00:00:00
abstract::This study uses a bovine patella model to compare the relative merits of on-bone compliance and thickness measurements, free-swelling behaviour, and structural imaging with differential interference contrast (DIC) light microscopy to assess the biomechanical normality of the cartilage matrix. The results demonstrate t...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.2003.00184.x
更新日期:2003-06-01 00:00:00
abstract::Cells migrating from the neural crest are known to septate the outflow tract of the developing heart, and to contribute to the formation of the arterial valves, their supporting sinuses, the coronary arteries and cardiac neural ganglia. Neural crest cells have also been suggested to contribute to development of the ve...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2007.00833.x
更新日期:2008-01-01 00:00:00
abstract::It is a challenge to understand how barn owls (Tyto alba) reduce noise during flight to be able to hunt small mammals by audition. Several specializations of the wing and the wing feathers have been implicated in noise reduction. What has been overlooked so far are the fringes at the inner vanes of remiges. We demonst...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2012.01504.x
更新日期:2012-07-01 00:00:00
abstract::There is need for a consistent definition of structures caudal to the testis that variously are termed 'gubernaculum testis' as a basis for understanding the emergence and sexually dimorphic further growth and differentiation of this specifically mammalian structure. Rodent fetuses undergo a stage of development durin...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1996-08-01 00:00:00
abstract::There is an accumulating body of evidence that highlights the fact that one can identify convergence in programmes of cellular differentiation. That is, that a particular differentiated cell/tissue type can be generated via non-identical paths. Convergence is also seen in evolution and here it is termed homoplasy, thu...
journal_title:Journal of anatomy
pub_type: 杂志文章,评审
doi:10.1111/j.1469-7580.2010.01232.x
更新日期:2010-06-01 00:00:00
abstract::The effects of chronic neuromuscular inactivity on the phenotype and size of muscle fibres in a fast ankle extensor (medial gastrocnemius, MG) and a fast ankle flexor (tibialis anterior, TA) muscle of the rat hindlimb were determined. Inactivity was produced by spinal cord isolation (SI), i.e. complete spinal cord tra...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2006.00665.x
更新日期:2007-01-01 00:00:00
abstract::Fertilised chicken eggs were incubated for 48 hours while exposed to pulsed trains of magnetic fields having a duration of 0-5 ms, a rise time of 42 microsecond, and a pulse repetition rate of 100 at a magnetic field flux density of 1 microT. Some eggs were exposed to 1,552 rad X-rays as a positive control. After expo...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1988-04-01 00:00:00
abstract::There is evidence for lymphatic drainage of interstitial fluid from the brain along perivascular spaces in a number of mammalian species. Ultrastructural studies suggest that there are similar drainage pathways in the human cerebral cortex. Perivascular spaces in the basal ganglia, however, differ from those in the co...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.1997.19130337.x
更新日期:1997-10-01 00:00:00
abstract::This paper reports on the development of a theoretical model to simulate the growth and repair of microdamage in bone. Unlike previous theories, which use simplified descriptions of damage, this approach models each individual microcrack explicitly, and also models the basic multicellular units (BMUs) that repair crac...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.2003.00194.x
更新日期:2003-08-01 00:00:00
abstract::The evolution of animal morphology can be understood as a series of changes in developmental programs. Among vertebrates, some developmental stages are conserved across species, representing particular developmental constraints. One of the most conserved stages is the vertebrate pharyngula, in which similar embryonic ...
journal_title:Journal of anatomy
pub_type: 杂志文章,评审
doi:10.1111/j.1469-7580.2005.00483.x
更新日期:2005-11-01 00:00:00
abstract::Kokartus honorarius from the Middle Jurassic (Bathonian) of Kyrgyzstan is one of the oldest salamanders in the fossil record, characterized by a mixture of plesiomorphic morphological features and characters shared with crown-group salamanders. Here we present a detailed histological analysis of its long bones. The an...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12281
更新日期:2015-04-01 00:00:00
abstract::Human beings have considerably expanded cognitive abilities compared with all other species and they also have a relatively larger cerebral cortex compared with their body size. But is a bigger brain the only reason for higher cognition or have other features evolved in parallel? Humans have more and different types o...
journal_title:Journal of anatomy
pub_type: 杂志文章,评审
doi:10.1111/joa.12198
更新日期:2015-10-01 00:00:00
abstract::The developing human brain can compensate for pre- and perinatally acquired focal lesions more effectively than the adult brain. The mechanisms by which this effective reorganization is achieved vary considerably between different functional systems, reflecting differences in the normal maturation of these systems. In...
journal_title:Journal of anatomy
pub_type: 杂志文章,评审
doi:10.1111/j.1469-7580.2010.01262.x
更新日期:2010-10-01 00:00:00
abstract::The distribution of mRNAs and antigens of tissue type (t) and urokinase type (u) plasminogen activators (PA) plus their corresponding inhibitors, type-1 (PAI-1) and type-2 (PAI-2) were studied in human and rhesus monkey placentae by in situ hybridisation and immunocytochemistry. Specific monkey cRNA and antibodies aga...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.1999.19420183.x
更新日期:1999-02-01 00:00:00
abstract::A quantitative, postmortem study of 36 human inferior alveolar nerves is described. The total myelinated fibre count (TMFC) of nerves was not related to sex or age of the subjects but significant positive correlations were found between TMFC and subject body weight in both dentate (r = 0.616) and edentulous (r = 0.676...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1987-04-01 00:00:00
abstract::Pulmonary alveolar septa are thought to contain at least two types of fibroblasts that are termed myofibroblasts and lipofibroblasts based on their morphological characteristics. Lipofibroblasts possess cytoplasmic lipid inclusions (lipid bodies or droplets) and are involved in several important functions, such as sur...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12677
更新日期:2017-12-01 00:00:00
abstract::The entire head and neck of a wild adult male Mongolian gazelle (Procapra gutturosa) was dissected with special reference to its enlarged larynx. Two additional adult male specimens taken from the wild were analysed by computer tomography. The sternomandibularis, omohyoideus, thyrohyoideus and hyoepiglotticus muscles ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.2003.00232.x
更新日期:2003-11-01 00:00:00
abstract::In most mammalian species the cardiac skeleton is composed of coarse collagen fibres, fibrocartilage, and pieces of hyaline cartilage. Bone, the os cordis, is a regular constituent of the ruminant heart. The cardiac skeleton of the otter (Lutra lutra) has not previously been described. The skeleton in 30 otter hearts ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.2000.19630485.x
更新日期:2000-04-01 00:00:00
abstract::Epiphyses of man and dog in various stages of union are described. As union approaches, new cartilage is added to the epiphyseal surface of the cartilaginous epiphyseal plate by chondrification of the epiphyseal marrow. Before and during early union the cellular arrangement of the cartilaginous epiphyseal plate is wel...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1975-09-01 00:00:00
abstract::The insulin/insulin-like growth factor (IGF) system regulates fetal and placental growth and development. In maternal diabetes, components of this system including insulin, IGF1, IGF2 and various IGF-binding proteins are deregulated in the maternal or fetal circulation, or in the placenta. The placenta expresses consi...
journal_title:Journal of anatomy
pub_type: 杂志文章,评审
doi:10.1111/j.1469-7580.2008.01035.x
更新日期:2009-07-01 00:00:00
abstract::The anterolateral ligament, a distinct structure connecting the lateral femoral epicondyle to the anterolateral proximal tibia, is gaining attention because of its possible function in ensuring internal rotational stability of the tibia. To study the prevalence and precise anatomical characteristics of the anterolater...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12826
更新日期:2018-08-01 00:00:00
abstract::Adult male Sprague-Dawley rats were randomly assigned to two groups: control and anaemic. Anaemia was induced by periodical blood withdrawal. Extensor digitorum longus and soleus muscles were excised under pentobarbital sodium total anaesthesia and processed for transmission electron microscopy, histochemical and bioc...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2008.00908.x
更新日期:2008-06-01 00:00:00
abstract::The vomeronasal system (VNS) has been extensively studied within specific animal families, such as Rodentia. However, the study of the VNS in other families, such as Canidae, has long been neglected. Among canids, the vomeronasal organ (VNO) has only been studied in detail in the dog, and no studies have examined the ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.13254
更新日期:2020-11-01 00:00:00
abstract::The retinal vasculature of postmortem normal human and diabetic eyes was studied using an immunohistochemical technique in conjunction with confocal laser scanning microscopy. The technique, which stained for von Willebrand factor, allowed both large areas of the retinal vasculature to be visualised and abnormalities ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.1999.19410089.x
更新日期:1999-01-01 00:00:00
abstract::The development of the patella, its associated tendons, and suprapatella of the rabbit knee joint is described from the 17 d fetus to the mature adult. The patellar tendon (ligament) with the patella on its posterior surface is seen in the 17 d fetus and is fully developed by 1 postnatal wk. It is composed of bundles ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.1997.19030327.x
更新日期:1997-04-01 00:00:00