Enhanced segregation of concurrent sounds with similar spectral uncertainties in individuals with autism spectrum disorder.

abstract：:Knee osteoarthritis (KOA) is reported to have characteristic kinematics during walking. However, the relationship between Kellgren-Lawrence (K/L) score and the 3D kinematic gait of patients with medial KOA remains unclear. Here, ninety-seven patients with medial KOA and thirty-eight asymptomatic participants were invo...

journal_title：Scientific reports

authors： Zeng X,Ma L,Lin Z,Huang W,Huang Z,Zhang Y,Mao C

更新日期：2017-06-22 00:00:00

abstract：:We investigated the surface reformation of poly(dimethylsiloxane) (PDMS) elastomers by means of ion beam bombardment for fabricating wrinkle structures. Oxidation on the PDMS surface formed a silica-like outer layer that interacted with the inner PDMS layer, leading to the formation of wrinkle structures that minimize...

journal_title：Scientific reports

authors： Park HG,Jeong HC,Jung YH,Seo DS

更新日期：2015-07-21 00:00:00

abstract：:Toll-like receptors (TLRs), as innate immunity sensors, play critical roles in immune responses. Six SNPs of TLR3, TLR7, and TLR8 were genotyped to determine their associations with systemic lupus erythematosus (SLE) and clinical manifestations of SLE. TLR7 SNP rs3853839 was independently associated with SLE susceptib...

journal_title：Scientific reports

authors： Wang CM,Chang SW,Wu YJ,Lin JC,Ho HH,Chou TC,Yang B,Wu J,Chen JY

更新日期：2014-01-21 00:00:00

abstract：:Siglec-2 undergoes constitutive endocytosis and is a drug target for autoimmune diseases and B cell-derived malignancies, including hairy cell leukaemia, marginal zone lymphoma, chronic lymphocytic leukaemia and non-Hodgkin's lymphoma (NHL). An alternative to current antibody-based therapies is the use of liposomal na...

journal_title：Scientific reports

authors： Madge PD,Maggioni A,Pascolutti M,Amin M,Waespy M,Bellette B,Thomson RJ,Kelm S,von Itzstein M,Haselhorst T

更新日期：2016-11-03 00:00:00

abstract：:CRISPR/Cas9 genome editing has revolutionized functional genomics in vertebrates. However, CRISPR/Cas9 edited F0 animals too often demonstrate variable phenotypic penetrance due to the mosaic nature of editing outcomes after double strand break (DSB) repair. Even with high efficiency levels of genome editing, phenotyp...

journal_title：Scientific reports

authors： Naert T,Tulkens D,Edwards NA,Carron M,Shaidani NI,Wlizla M,Boel A,Demuynck S,Horb ME,Coucke P,Willaert A,Zorn AM,Vleminckx K

更新日期：2020-09-04 00:00:00

abstract：:The nucleotides guanosine tetraphosphate and pentaphosphate (together known as (p)ppGpp or magic spot) are produced in plant plastids from GDP/GTP and ATP by RelA-SpoT homologue (RSH) enzymes. In the model plant Arabidopsis (p)ppGpp regulates chloroplast transcription and translation to affect growth, and is also impl...

journal_title：Scientific reports

authors： Avilan L,Puppo C,Villain A,Bouveret E,Menand B,Field B,Gontero B

更新日期：2019-11-27 00:00:00

abstract：:Tuberculosis, a severe infectious disease caused by the Mycobacterium tuberculosis, arouses huge concerns globally. In this study, a total of 331,594 TB cases in Zhejiang Province were notified during the period of 2009-2018 with the gender ratio of male to female 2.16:1. The notified TB incidences demonstrated a cont...

journal_title：Scientific reports

authors： Liu K,Li T,Vongpradith A,Wang F,Peng Y,Wang W,Chai C,Chen S,Zhang Y,Zhou L,Chen X,Bian Q,Chen B,Wang X,Jiang J

更新日期：2020-05-04 00:00:00

abstract：:Sleep has been hypothesised to maintain a close relationship with metabolism. Here we focus on the brain structure that triggers slow-wave sleep, the ventrolateral preoptic nucleus (VLPO), to explore the cellular and molecular signalling pathways recruited by an increase in glucose concentration. We used infrared vide...

journal_title：Scientific reports

authors： Scharbarg E,Daenens M,Lemaître F,Geoffroy H,Guille-Collignon M,Gallopin T,Rancillac A

更新日期：2016-01-12 00:00:00

abstract：:The role of marginal populations for the long-term maintenance of species' genetic diversity and evolutionary potential is particularly timely in view of the range shifts caused by climate change. The Centre-Periphery hypothesis predicts that marginal populations should bear reduced genetic diversity and have low evol...

journal_title：Scientific reports

authors： Ciborowski K,Jordan WC,Garcia de Leaniz C,Consuegra S

更新日期：2017-02-10 00:00:00

abstract：:Chaotic time series prediction based on nonlinear systems showed a superior performance in prediction field. We studied prenatal exposure to polychlorinated biphenyls (PCBs) by chaotic time series prediction using the least squares self-exciting threshold autoregressive (SEATR) model in umbilical cord blood in an elec...

journal_title：Scientific reports

authors： Xu X,Tang Q,Xia H,Zhang Y,Li W,Huo X

更新日期：2016-04-27 00:00:00

abstract：:Lung adenosquamous cell carcinomas (ASCs) is a rare variant of NSCLC with a poorer prognosis and fewer treatment option than the more common variants. PD-L1 expression is reported to be the predictor of clinical response in trials of NSCLC. In our study, PD-L1 expression was evaluated via immunohistochemistry using a ...

journal_title：Scientific reports

authors： Shi X,Wu S,Sun J,Liu Y,Zeng X,Liang Z

更新日期：2017-04-07 00:00:00

abstract：:The association between blood urea nitrogen to creatinine ratio (UCR) and survival is uncertain in hemodialysis patients. We examined the influence of UCR on mortality and morbidity in hemodialysis patients. A total of 3,401 hemodialysis patients were prospectively followed for 4 years. The association between UCR wit...

journal_title：Scientific reports

authors： Tanaka S,Ninomiya T,Taniguchi M,Tokumoto M,Masutani K,Ooboshi H,Kitazono T,Tsuruya K

更新日期：2017-11-02 00:00:00

abstract：:Quality assessment of protein models using no other information than the structure of the model itself has been shown to be useful for structure prediction. Here, we introduce two novel methods, ProQRosFA and ProQRosCen, inspired by the state-of-art method ProQ2, but using a completely different description of a prote...

journal_title：Scientific reports

authors： Uziela K,Shu N,Wallner B,Elofsson A

更新日期：2016-10-04 00:00:00

abstract：:Fusarium head blight (FHB) is a devastating disease of wheat worldwide. Fhb1 is the most consistently reported quantitative trait locus (QTL) for FHB resistance breeding. A pore-forming toxin-like (PFT) gene at Fhb1 was first cloned by map-based cloning and found to confer FHB resistance in wheat. Proteins often inter...

journal_title：Scientific reports

authors： He Y,Wu L,Liu X,Zhang X,Jiang P,Ma H

更新日期：2019-10-29 00:00:00

abstract：:Short term treatment with low doses of glucocorticoid analogues has been shown to ameliorate neurological symptoms in Ataxia-Telangiectasia (A-T), a rare autosomal recessive multisystem disease that mainly affects the cerebellum, immune system, and lungs. Molecular mechanisms underlying this clinical observation are u...

journal_title：Scientific reports

authors： Pozzi E,Giorgio E,Mancini C,Lo Buono N,Augeri S,Ferrero M,Di Gregorio E,Riberi E,Vinciguerra M,Nanetti L,Bianchi FT,Sassi MP,Costanzo V,Mariotti C,Funaro A,Cavalieri S,Brusco A

更新日期：2020-11-19 00:00:00

abstract：:The pectin methylesterase action is usually studied in a homogeneous aqueous medium in the presence of a large excess of soluble substrate and water. However in the cell wall, the water content is much lower, the substrate is cross-linked with itself or with other polymers, and the enzyme has to diffuse through the so...

journal_title：Scientific reports

authors： Bonnin E,Alvarado C,Crépeau MJ,Bouchet B,Garnier C,Jamme F,Devaux MF

更新日期：2019-08-29 00:00:00

abstract：:The differential conductance of graphene is shown to exhibit a zero-bias anomaly at low temperatures, arising from a suppression of the quantum corrections due to weak localization and electron interactions. A simple rescaling of these data, free of any adjustable parameters, shows that this anomaly exhibits a univers...

journal_title：Scientific reports

authors： Somphonsane R,Ramamoorthy H,He G,Nathawat J,Yin S,Kwan CP,Arabchigavkani N,Barut B,Zhao M,Jin Z,Fransson J,Bird JP

更新日期：2020-03-27 00:00:00

abstract：:In external radiotherapy (RT), the use of flattening filter-free (FFF) radiation beams obtained by removing the flattening filter (FF) in standard linear accelerators is rapidly increasing, and the benefits of clinical use are the issue of research. Advanced treatment techniques have increased the interest in the oper...

journal_title：Scientific reports

authors： Arslan A,Sengul B

更新日期：2020-06-02 00:00:00

abstract：:Thermal rectifiers whose forward heat fluxes are greater than reverse counterparts have been extensively studied. Here we have discovered, idealized, and derived the ultimate limit of such rectification ratios, which are partially validated by numerical simulations, experiments, and micro-scale Hamiltonian-oscillator ...

journal_title：Scientific reports

authors： Shih TM,Gao Z,Guo Z,Merlitz H,Pagni PJ,Chen Z

更新日期：2015-08-04 00:00:00

abstract：:Here we report an ABA triblock copolymer that can express microscopic autonomous formation and break-up of aggregates under constant condition to generate macroscopic viscoelastic self-oscillation of the solution. The ABA triblock copolymer is designed to have hydrophilic B segment and self-oscillating A segment at th...

journal_title：Scientific reports

authors： Onoda M,Ueki T,Shibayama M,Yoshida R

更新日期：2015-10-29 00:00:00

abstract：:Outer membrane vesicles (OMVs) produced by Gram-negative bacteria have roles in cell-to-cell signaling, biofilm formation, and stress responses. Here, the effects of abiotic stressors on OMV contents and composition from biofilm cells of the plant health-promoting bacterium Pseudomonas chlororaphis O6 (PcO6) are exami...

journal_title：Scientific reports

authors： Potter M,Hanson C,Anderson AJ,Vargis E,Britt DW

更新日期：2020-12-04 00:00:00

abstract：:Measurement techniques that allow the global analysis of cellular responses while retaining single-cell sensitivity are increasingly needed in order to understand complex and dynamic biological processes. In this context, compromises between sensitivity, degree of multiplexing, throughput, and invasiveness are often u...

journal_title：Scientific reports

authors： Pavillon N,Smith NI

更新日期：2019-11-19 00:00:00

abstract：:Exposure to stress during early life affects subsequent behaviors and increases the vulnerability to adult pathologies, a phenomenon that has been well documented in humans and rodents. In this study, we introduce a chronic unpredictable stress protocol adapted to young zebrafish, which is an increasingly popular vert...

journal_title：Scientific reports

authors： Golla A,Østby H,Kermen F

更新日期：2020-06-25 00:00:00

abstract：:The South American Monsoon System (SAMS) is generally considered to be highly sensitive to Northern Hemisphere (NH) temperature variations on multi-centennial timescales. The direct influence of solar forcing on moisture convergence in global monsoon systems on the other hand, while well explored in modeling studies, ...

journal_title：Scientific reports

authors： Novello VF,Vuille M,Cruz FW,Stríkis NM,de Paula MS,Edwards RL,Cheng H,Karmann I,Jaqueto PF,Trindade RI,Hartmann GA,Moquet JS

更新日期：2016-04-21 00:00:00

abstract：:Meteorite impacts have caused catastrophic perturbations to the global environment and mass extinctions throughout the Earth's history. Here, we present petrographic and geochemical evidence of a possible impact ejecta layer, dating from about 11 Ma, in deep-sea clayey sediment in the Northwest Pacific. This clay laye...

journal_title：Scientific reports

authors： Nozaki T,Ohta J,Noguchi T,Sato H,Ishikawa A,Takaya Y,Kimura JI,Chang Q,Shimada K,Ishibashi JI,Yasukawa K,Kimoto K,Iijima K,Kato Y

更新日期：2019-11-20 00:00:00

abstract：:Liquid pumping can occur along the outer surface of an electrode under a DC electric field. For biological applications, a better understanding of the ionic solution pumping mechanism is required. Here, we fabricated CNT wire electrodes (CWEs) and tungsten wire electrodes (TWEs) of various diameters to assess an ionic...

journal_title：Scientific reports

authors： Shin JH,Kim GH,Kim I,Jeon H,An T,Lim G

更新日期：2015-07-02 00:00:00

abstract：:The synthesis and subsequent genomic integration of DNA that is complementary to the genomes of non-retroviral RNA viruses are rarely observed. However, upon infection of various human cell lines and primary fibroblasts with the vesicular stomatitis virus (VSV), we detected DNA complementary to the VSV RNA. The VSV DN...

journal_title：Scientific reports

authors： Shimizu A,Nakatani Y,Nakamura T,Jinno-Oue A,Ishikawa O,Boeke JD,Takeuchi Y,Hoshino H

更新日期：2014-05-30 00:00:00

abstract：:Oxygen tolerance of selenium-containing [NiFeSe] hydrogenases (Hases) is attributable to the high reducing power of the selenocysteine residue, which sustains the bimetallic Ni-Fe catalytic center in the large subunit. Genes encoding [NiFeSe] Hases are inherited by few sulphate-reducing δ-proteobacteria globally distr...

journal_title：Scientific reports

authors： Tamura T,Tsunekawa N,Nemoto M,Inagaki K,Hirano T,Sato F

更新日期：2016-01-28 00:00:00

abstract：:Numerous essential metal elements (EMEs) are necessary to maintain the proper function of human body. In this case-control study, we investigated the associations of 11 EMEs [Calcium (Ca), potassium (K), magnesium (Mg), sodium (Na), manganese (Mn), selenium (Se), cobalt (Co), Molybdenum (Mo), copper (Cu), zinc (Zn), a...

journal_title：Scientific reports

authors： Ma J,Yan L,Guo T,Yang S,Liu Y,Xie Q,Ni D,Wang J

更新日期：2020-07-03 00:00:00

abstract：:We collected Solidago altissima clones to explore their leaf damage resistance, and as a result identified five accessions that exhibited variable defense abilities against the generalist herbivore Spodoptera litura. In order to characterize molecules involved in such natural variation, we focused on ethylene response...

journal_title：Scientific reports

authors： Takafuji K,Rim H,Kawauchi K,Mujiono K,Shimokawa S,Ando Y,Shiojiri K,Galis I,Arimura GI

更新日期：2020-03-24 00:00:00