当前位置： SCI文献检索 > Journal of Diabetes期刊下所有文献 > Simple non-laboratory- and laboratory-based risk assessment algorithms and nomogram for detecting undiagnosed diabetes mellitus.

Simple non-laboratory- and laboratory-based risk assessment algorithms and nomogram for detecting undiagnosed diabetes mellitus.

Abstract：

BACKGROUND:The aim of the present study was to develop a simple nomogram that can be used to predict the risk of diabetes mellitus (DM) in the asymptomatic non-diabetic subjects based on non-laboratory- and laboratory-based risk algorithms. METHODS:Anthropometric data, plasma fasting glucose, full lipid profile, exercise habits, and family history of DM were collected from Chinese non-diabetic subjects aged 18-70 years. Logistic regression analysis was performed on a random sample of 2518 subjects to construct non-laboratory- and laboratory-based risk assessment algorithms for detection of undiagnosed DM; both algorithms were validated on data of the remaining sample (n = 839). The Hosmer-Lemeshow test and area under the receiver operating characteristic (ROC) curve (AUC) were used to assess the calibration and discrimination of the DM risk algorithms. RESULTS:Of 3357 subjects recruited, 271 (8.1%) had undiagnosed DM defined by fasting glucose ≥7.0 mmol/L or 2-h post-load plasma glucose ≥11.1 mmol/L after an oral glucose tolerance test. The non-laboratory-based risk algorithm, with scores ranging from 0 to 33, included age, body mass index, family history of DM, regular exercise, and uncontrolled blood pressure; the laboratory-based risk algorithm, with scores ranging from 0 to 37, added triglyceride level to the risk factors. Both algorithms demonstrated acceptable calibration (Hosmer-Lemeshow test: P = 0.229 and P = 0.483) and discrimination (AUC 0.709 and 0.711) for detection of undiagnosed DM. CONCLUSION:A simple-to-use nomogram for detecting undiagnosed DM has been developed using validated non-laboratory-based and laboratory-based risk algorithms.

journal_name

J Diabetes

journal_title

Journal of diabetes

authors

Wong CK,Siu SC,Wan EY,Jiao FF,Yu EY,Fung CS,Wong KW,Leung AY,Lam CL

doi

10.1111/1753-0407.12310

subject

Has Abstract

pub_date

2016-05-01 00:00:00

pages

414-21

issue

3

eissn

1753-0393

issn

1753-0407

journal_volume

8

pub_type

杂志文章

相关文献

Journal of Diabetes文献大全
  • Associations of smoking and alcohol consumption with impaired β-cell function in Chinese men.

    abstract：BACKGROUND:The aims of the present study were to examine the association of cigarette smoking and alcohol consumption with impaired β-cell function in Chinese men, particularly the interaction of smoking and alcohol consumption on impaired insulin secretion. METHODS:A population-based cross-sectional study was perform...

    journal_title：Journal of diabetes

    pub_type： 杂志文章

    doi：10.1111/1753-0407.12314

    authors： Xu M,Zhou Y,Xu B,Sun J,Wang T,Lu J,Lai S,Bi Y,Wang W,Ning G

    更新日期：2016-05-01 00:00:00

  • Lung function and metabolic syndrome: Findings of National Health and Nutrition Examination Survey 2007–2010.

    abstract：BACKGROUND:Considerable uncertainty remains about obstructive lung function( OLF) in adults with metabolic syndrome (MetS). The aim of the present study was to examine pulmonary function status in adults with and without MetS. METHODS:We used data from 3109 participants aged ≥20 years of the National Health and Nutrit...

    journal_title：Journal of diabetes

    pub_type： 杂志文章

    doi：10.1111/1753-0407.12136

    authors： Ford ES,Cunningham TJ,Mercado CI

    更新日期：2014-11-01 00:00:00

  • DNA methylation of tumor necrosis factor-α, monocyte chemoattractant protein-1, and adiponectin genes in visceral adipose tissue is related to type 2 diabetes in the Xinjiang Uygur population.

    abstract：BACKGROUND:The higher probability of type 2 diabetes mellitus (T2DM) in the Uygur population is due to a greater waist:  hip ratio and visceral fat. This study investigated DNA methylation of tumor necrosis factor-α (TNF), monocyte chemoattractant protein-1 (MCP1), and adiponectin (ADIPOQ) in visceral adipose tissue in...

    journal_title：Journal of diabetes

    pub_type： 杂志文章

    doi：10.1111/1753-0407.12478

    authors： Zhang J,Wang C,Ha X,Li W,Xu P,Gu Y,Wang T,Wang Y,Xie J

    更新日期：2017-07-01 00:00:00

  • Liver X receptor activation increases hepatic fatty acid desaturation by the induction of SCD1 expression through an LXRα-SREBP1c-dependent mechanism.

    abstract：BACKGROUND:Liver X receptors (LXRs) including LXRα and LXRβ are members of the nuclear hormone receptor superfamily of ligand activated transcription factors, which serve as lipid sensors to regulate expression of genes controlling many aspects of cholesterol and fatty acid metabolism. The liver is the central organ in...

    journal_title：Journal of diabetes

    pub_type： 杂志文章

    doi：10.1111/1753-0407.12081

    authors： Zhang X,Liu J,Su W,Wu J,Wang C,Kong X,Gustafsson JÅ,Ding J,Ma X,Guan Y

    更新日期：2014-05-01 00:00:00

  • A randomized clinical trial evaluating the safety and efficacy of sitagliptin added to the combination of sulfonylurea and metformin in patients with type 2 diabetes mellitus and inadequate glycemic control.

    abstract：BACKGROUND:Type 2 diabetes mellitus (T2DM) treatment generally requires multiple antihyperglycemic agents. When diet, exercise, and treatment with sulfonylurea and metformin do not achieve glycemic goals, several options are available. The present study evaluated the efficacy and tolerability of sitagliptin 100 mg/day ...

    journal_title：Journal of diabetes

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1111/1753-0407.12351

    authors： Moses RG,Round E,Shentu Y,Golm GT,O'neill EA,Gantz I,Engel SS,Kaufman KD,Goldstein BJ

    更新日期：2016-09-01 00:00:00

  • Serum concentrations of vitamin D and parathyroid hormone and prevalent metabolic syndrome among adults in the United States.

    abstract：BACKGROUND:Some reports suggest that concentrations of vitamin D are inversely, whereas concentrations of parathyroid hormone (PTH) are directly, associated with prevalent metabolic syndrome. Because of lingering uncertainty about these associations, we examined the cross-sectional associations between serum concentrat...

    journal_title：Journal of diabetes

    pub_type： 杂志文章

    doi：10.1111/j.1753-0407.2009.00046.x

    authors： Ford ES,Zhao G,Li C,Pearson WS

    更新日期：2009-12-01 00:00:00

  • Skin autofluorescence is increased in young people with type 1 diabetes exposed to secondhand smoking.

    abstract：:Skin autofluorescence is increased in diabetes, rises with age, and predicts diabetes-related complications. Exposure to secondhand smoke, because one or more family members are smokers, further increases skin autofluorescence in children and young adults with type 1 diabetes. Elimination of passive smoking should be ...

    journal_title：Journal of diabetes

    pub_type： 信件

    doi：10.1111/1753-0407.12498

    authors： Vollenbrock CE,Van Waateringe RP,Veeze HJ,Aanstoot HJ,Wolffenbuttel BH

    更新日期：2017-03-01 00:00:00

  • Comparative efficacy of nine different dressings in healing diabetic foot ulcer: A Bayesian network analysis.

    abstract：BACKGROUND:There is a wide variety of dressings currently available for the treatment of diabetic foot ulcers (DFUs). Because of a lack of evidence from head-to-head randomized controlled trials (RCTs), the relative effects of these dressings in DFU patients remain unclear. This study compared the efficacy of nine dres...

    journal_title：Journal of diabetes

    pub_type： 杂志文章

    doi：10.1111/1753-0407.12871

    authors： Zhang X,Sun D,Jiang GC

    更新日期：2019-06-01 00:00:00

  • Relationship between CA 19-9 levels and glucose regulation in a middle-aged and elderly Chinese population.

    abstract：OBJECTIVE:To investigate carbohydrate antigen (CA) 19-9 levels in subjects with different glucose regulation status and assess the relationship between CA 19-9 and glucose regulation status in a Chinese population aged 40 years and older. METHODS:A total of 2792 participants aged 40 years or older with no history of d...

    journal_title：Journal of diabetes

    pub_type： 杂志文章

    doi：10.1111/j.1753-0407.2011.00179.x

    authors： Huang Y,Xu Y,Bi Y,Xu M,Lu J,Wang T,Li M,Chen Y,Liu Y,Huang F,Xu B,Zhang J,Wang W,Ning G

    更新日期：2012-06-01 00:00:00

  • Angiotensin-converting enzyme (ACE) gene II genotype protects against the development of diabetic peripheral neuropathy in type 2 diabetes mellitus.

    abstract：BACKGROUND:  Diabetic peripheral neuropathy (DPN) is one of the complications of type 2 diabetes mellitus (T2DM) that decreases the quality of life of T2DM patients. Very few studies have found an association between the development and progression of DPN in T2DM and angiotensin-converting enzyme (ACE) gene insertion/d...

    journal_title：Journal of diabetes

    pub_type： 杂志文章

    doi：10.1111/j.1753-0407.2012.00205.x

    authors： Mansoor Q,Javaid A,Bilal N,Ismail M

    更新日期：2012-09-01 00:00:00

  • Glucagon-like peptide 1-potentiated insulin secretion and proliferation of pancreatic β-cells.

    abstract：:Glucagon-like peptide-1 (GLP-1) is the primary incretin hormone secreted from the intestine upon uptake of food to stimulate insulin secretion from pancreatic β-cells. GLP-1 exerts its effects by binding to its G-protein coupled receptors and subsequently activating adenylate cyclase, leading to generation of cyclic a...

    journal_title：Journal of diabetes

    pub_type： 杂志文章,评审

    doi：10.1111/1753-0407.12161

    authors： Ma X,Guan Y,Hua X

    更新日期：2014-09-01 00:00:00

  • Ethnic disparities in relationships of obesity indices with telomere length in Asians with type 2 diabetes.

    abstract：BACKGROUND:Obesity and shorter telomeres increase the risk for diabetes complications and mortality. However, the relationship between obesity and telomere length in diverse Asian populations with type 2 diabetes (T2D) is not well understood. This study examined the association of baseline and changes in obesity indice...

    journal_title：Journal of diabetes

    pub_type： 杂志文章

    doi：10.1111/1753-0407.12864

    authors： Gurung RL,M Y,Liu S,Liu JJ,Chan SM,Moh MC,Ang K,Tang WE,Sum CF,Tavintharan S,Lim SC,SMART2D Study.

    更新日期：2019-05-01 00:00:00

  • G protein-coupled receptor kinase-2: A potential biomarker for early diabetic cardiomyopathy.

    abstract：BACKGROUND:G protein-coupled receptor kinase-2 (GRK2) has been shown as a key regulator of cardiac function, and the myocardial GRK2 levels are mirrored by the levels in peripheral blood mononuclear cells (PBMCs). In this study, we evaluated the myocardial and PBMCs GRK2 levels in early diabetic cardiomyopathy (DCM). ...

    journal_title：Journal of diabetes

    pub_type： 杂志文章

    doi：10.1111/1753-0407.12991

    authors： Lai S,Fu X,Yang S,Zhang S,Lin Q,Zhang M,Chen H

    更新日期：2020-03-01 00:00:00

  • Factor analysis of metabolic syndrome components and predicting type 2 diabetes: Results of 10-year follow-up in a Middle Eastern population.

    abstract：BACKGROUND:The relationship among components of metabolic syndrome (MetS) and their association with diabetes is unclear in West Asia. The aim of the present study was to conduct factor analysis of MetS components and the effect these factors have on the incidence of type 2 diabetes (T2D) in a population-based cohort s...

    journal_title：Journal of diabetes

    pub_type： 杂志文章

    doi：10.1111/1753-0407.12252

    authors： Ayubi E,Khalili D,Delpisheh A,Hadaegh F,Azizi F

    更新日期：2015-11-01 00:00:00

  • Elucidation of the novel role of ethnicity and diabetes in poorer outcomes after cardiac surgery in a multiethnic Southeast Asian cohort.

    abstract：BACKGROUND:Although diabetes is associated with ethnicity and worse cardiac surgery outcomes, no research has been done to study the effect of both diabetes and ethnicity on cardiac surgery outcomes in a multiethnic Southeast Asian cohort. Hence, this study aimed to delineate the association of ethnicity on outcomes af...

    journal_title：Journal of diabetes

    pub_type： 杂志文章

    doi：10.1111/1753-0407.12961

    authors： Moorthy V,Liu W,Chan SP,Chew STH,Ti LK

    更新日期：2020-01-01 00:00:00

  • Intracellular and extracellular adenosine triphosphate in regulation of insulin secretion from pancreatic β cells (β).

    abstract：:Adenosine triphosphate (ATP) synthesis and release in mitochondria play critical roles in regulating insulin secretion in pancreatic β cells. Mitochondrial dysfunction is mainly characterized by a decrease in ATP production, which is a central event in the progression of pancreatic β cell dysfunction and diabetes. ATP...

    journal_title：Journal of diabetes

    pub_type： 杂志文章,评审

    doi：10.1111/1753-0407.12098

    authors： Wang C,Geng B,Cui Q,Guan Y,Yang J

    更新日期：2014-03-01 00:00:00

  • Post-partum plasma C-peptide and ghrelin concentrations are predictive of type 2 diabetes in women with previous gestational diabetes mellitus.

    abstract：BACKGROUND:Women with previous gestational diabetes mellitus (pGDM) are at increased risk of developing type 2 diabetes later in life. The aim of this study was to determine if circulating levels of metabolic hormones 12 weeks following a GDM pregnancy are associated with an increased risk of type 2 diabetes 8-10 years...

    journal_title：Journal of diabetes

    pub_type： 杂志文章

    doi：10.1111/1753-0407.12209

    authors： Lappas M,Jinks D,Ugoni A,Louizos CC,Permezel M,Georgiou HM

    更新日期：2015-07-01 00:00:00

  • Review of gastroesophageal reflux disease (GERD) in the diabetic patient.

    abstract：:This article reviews the known pathophysiological mechanisms of comorbid gastroesophageal reflux disease (GERD) in the diabetic patient, discusses therapeutic options in care, and provides an approach to its evaluation and management. We searched for review articles published in the past 10 years through a PubMed sear...

    journal_title：Journal of diabetes

    pub_type： 杂志文章,评审

    doi：10.1111/1753-0407.12279

    authors： Punjabi P,Hira A,Prasad S,Wang X,Chokhavatia S

    更新日期：2015-09-01 00:00:00

  • Comparing the effects of 6 months aerobic exercise and resistance training on metabolic control and β-cell function in Chinese patients with prediabetes: A multicenter randomized controlled trial.

    abstract：BACKGROUND:It is clear that aerobic training (AT) can delay pancreatic exhaustion and slow the progression from prediabetes to type 2 diabetes (T2D), but there is little information regarding the effects of resistance training (RT) in people with prediabetes. This study compared the effectiveness of RT and AT in improv...

    journal_title：Journal of diabetes

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1111/1753-0407.12955

    authors： Yuan X,Dai X,Liu L,Hsue C,Miller JD,Fang Z,Li J,Feng J,Huang Y,Liu C,Shen J,Chen T,Liu Y,Mordes J,Lou Q

    更新日期：2020-01-01 00:00:00

  • Stage of obesity epidemic model: Learning from tobacco control and advocacy for a framework convention on obesity control.

    abstract：:The 2011 United Nations political declaration against non-communicable diseases (NCDs) targeted four major risk factors: tobacco use, harmful use of alcohol, an unhealthy diet, and a lack of physical activity. The Framework Convention on Tobacco Control (FCTC), MPOWER strategies, and the four-stage model of the tobacc...

    journal_title：Journal of diabetes

    pub_type： 杂志文章,评审

    doi：10.1111/1753-0407.12647

    authors： Xu L,Lam TH

    更新日期：2018-07-01 00:00:00

  • Index of myocardial performance in patients with type 2 diabetes without hypertension and its relationship with clinical and echocardiographic parameters.

    abstract：BACKGROUND:Diabetes mellitus affects the systolic and diastolic function of the left ventricle (LV). The aim of the present study was to evaluate the index of myocardial performance (IMP), a new Doppler index, in asymptomatic, normotensive patients with type 2 diabetes mellitus (T2DM). METHODS:The study population con...

    journal_title：Journal of diabetes

    pub_type： 杂志文章

    doi：10.1111/j.1753-0407.2008.00005.x

    authors： Saglam H,Seyfeli E,Gul I,Duru M,Gokce C

    更新日期：2009-03-01 00:00:00

  • Efficacy and safety of pregabalin for painful diabetic peripheral neuropathy in a population of Chinese patients: A randomized placebo-controlled trial.

    abstract：BACKGROUND:Limited information exists regarding the efficacy of pregabalin in Chinese patients with painful diabetic peripheral neuropathy (pDPN). METHODS:An 11-week double-blind placebo-controlled trial was performed in Chinese pDPN patients randomized (1 : 1) to 300 mg/day pregabalin or placebo. The primary outcome ...

    journal_title：Journal of diabetes

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1111/1753-0407.12585

    authors： Mu Y,Liu X,Li Q,Chen K,Liu Y,Lv X,Xu X,Fan D,Shang N,Yang R,Pauer L,Pan C

    更新日期：2018-03-01 00:00:00

  • Glycemic effects of vildagliptin and metformin combination therapy in Indian patients with type 2 diabetes: an observational study.

    abstract：BACKGROUND:To analyze the glycemic response of Indian patients with type2 diabetes mellitus (T2DM) to combination therapy with vildagliptin and metformin and compare our data with those of clinical trials. METHODS:In a retrospective study of the hospital database, the glycemic control of 280 patients with T2DM who wer...

    journal_title：Journal of diabetes

    pub_type： 杂志文章

    doi：10.1111/1753-0407.12078

    authors： Chatterjee S,Chatterjee S

    更新日期：2014-05-01 00:00:00

  • Ocular autofluorescence in diabetes mellitus. A review.

    abstract：:Diabetes mellitus is a metabolic disease with a considerable impact on healthcare owing to its increased prevalence and high mortality rate. Structural, morphological, and physiological changes in each of the ocular components have been described in detail. Autofluorescence has been described as a good indicator of me...

    journal_title：Journal of diabetes

    pub_type： 杂志文章,评审

    doi：10.1111/1753-0407.12423

    authors： Calvo-Maroto AM,Perez-Cambrodi RJ,Garcia-Lazaro S,Ferrer-Blasco T,Cerviño A

    更新日期：2016-09-01 00:00:00

  • Omeprazole improves the anti-obesity and antidiabetic effects of exendin-4 in db/db mice (-4 db/db)*.

    abstract：BACKGROUND:In addition to its glucoregulatory actions, exendin-4, a stable glucagon-like peptide-1 receptor agonist, exhibits protective effects in the pancreas and anti-obesity effects. Suitable combination treatment with other anti-obesity or pancreas protective agents would be an effective approach to optimize these...

    journal_title：Journal of diabetes

    pub_type： 杂志文章

    doi：10.1111/j.1753-0407.2012.00227.x

    authors： Patel V,Joharapurkar A,Gandhi T,Patel K,Dhanesha N,Kshirsagar S,Dhote V,Detroja J,Bahekar R,Jain M

    更新日期：2013-06-01 00:00:00

  • Fish oil and wheat germ oil supplementation modulates brain injury in streptozotocin-induced diabetic rats.

    abstract：BACKGROUND:Uncontrolled diabetes mellitus causes neuronal damage because of increased intracellular glucose. Natural products as complementary therapy may reduce neuronal complications. This study investigated whether fish oil (FO) and wheat germ oil (WGO) supplementation protects the brain in streptozotocin (STZ)-indu...

    journal_title：Journal of diabetes

    pub_type： 杂志文章

    doi：10.1111/1753-0407.12518

    authors： Khedr NF

    更新日期：2017-11-01 00:00:00

  • Diabetes mellitus prevalence is increasing in South Asians but is stable in Chinese living in Singapore and Mauritius.

    abstract：BACKGROUND:Asia is experiencing a type 2 diabetes epidemic, but prevalence differs by ethnicity and level of socioeconomic development. Singapore and Mauritius have implemented comprehensive campaigns to address this public health problem. We compared diabetes and obesity prevalence trends among Chinese and South Asian...

    journal_title：Journal of diabetes

    pub_type： 杂志文章

    doi：10.1111/1753-0407.12497

    authors： Tan KHX,Barr ELM,Koshkina V,Ma S,Kowlessur S,Magliano DJ,Söderberg S,Chia KS,Zimmet P,Lim WY

    更新日期：2017-09-01 00:00:00

  • Genetic predisposition to gestational glucose metabolism and gestational diabetes mellitus risk in a Chinese population.

    abstract：BACKGROUND:Genome-wide association studies (GWAS) have identified several genetic variants affecting gestational glucose metabolism. However, information regarding their known associations with gestational diabetes mellitus (GDM) risk remains scarce. METHODS:This study examined the associations of 12 gestational gluco...

    journal_title：Journal of diabetes

    pub_type： 杂志文章

    doi：10.1111/1753-0407.12923

    authors： Xie K,Zhang Y,Wen J,Chen T,Kong J,Zhang J,Wu X,Hu C,Xu B,Ji C,Guo X,Wu J

    更新日期：2019-11-01 00:00:00

  • Is diabetes an independent risk factor for in-hospital complications after a stroke? ？.

    abstract：BACKGROUND:Patients with diabetes mellitus (DM) are more likely to develop in-hospital complications (IHCs) than patients without DM. In addition, they have poorer outcomes after an ischemic stroke (IS). Our goal was to evaluate whether the increase in risk for the development of IHCs in patients with IS is due to DM p...

    journal_title：Journal of diabetes

    pub_type： 杂志文章

    doi：10.1111/1753-0407.12222

    authors： Cruz-Herranz A,Fuentes B,Martínez-Sánchez P,Ruiz-Ares G,Lara-Lara M,Sanz-Cuesta B,Díez-Tejedor E

    更新日期：2015-09-01 00:00:00

  • Serum adipocyte fatty acid-binding protein levels are associated with peripheral arterial disease in women, but not men, with type 2 diabetes mellitus.

    abstract：BACKGROUND:Adipocyte fatty acid-binding protein (A-FABP) has been recognized as an important player in macrophage cholesterol trafficking and inflammation, and may promote the development of atherosclerosis. To further elucidate the role of A-FABP in atherosclerosis in diabetes, we investigated the relationship between...

    journal_title：Journal of diabetes

    pub_type： 杂志文章

    doi：10.1111/1753-0407.12549

    authors： Ding M,Shi JY,Xing YZ,Sun B,Fang QH,Zhang JY,Zhang QM,Chen LM,Yu DM,Li CJ

    更新日期：2018-06-01 00:00:00