Index of myocardial performance in patients with type 2 diabetes without hypertension and its relationship with clinical and echocardiographic parameters.

abstract：BACKGROUND:Mitogen-inducible gene 6 (Mig-6) has an important role in the regulation of cholesterol homeostasis and bile acid synthesis. However, the physiological functions of Mig-6 in the liver remain poorly understood. METHODS:To investigate Mig-6 functioning in the liver, we used conditionally ablated Mig-6 using t...

journal_title：Journal of diabetes

authors： Yoo JY,Kim TH,Kong S,Lee JH,Choi W,Kim KS,Kim HJ,Jeong JW,Ku BJ

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Women with previous gestational diabetes mellitus (pGDM) are at increased risk of developing type 2 diabetes later in life. The aim of this study was to determine if circulating levels of metabolic hormones 12 weeks following a GDM pregnancy are associated with an increased risk of type 2 diabetes 8-10 years...

journal_title：Journal of diabetes

authors： Lappas M,Jinks D,Ugoni A,Louizos CC,Permezel M,Georgiou HM

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:The effect of postload glucose spikes (PGS), the difference between 2 hour post-load plasma glucose (2hPLPG) and fasting plasma glucose (FPG), on post-myocardial infarction (post-MI) prognosis in nondiabetic patients is unexplored. METHODS:This is a retrospective cohort analysis of 847 nondiabetic post-MI s...

journal_title：Journal of diabetes

authors： Chattopadhyay S,George A,John J,Sathyapalan T

更新日期：2021-03-01 00:00:00

abstract：BACKGROUND:The aims of the present study were to examine the association of cigarette smoking and alcohol consumption with impaired β-cell function in Chinese men, particularly the interaction of smoking and alcohol consumption on impaired insulin secretion. METHODS:A population-based cross-sectional study was perform...

journal_title：Journal of diabetes

authors： Xu M,Zhou Y,Xu B,Sun J,Wang T,Lu J,Lai S,Bi Y,Wang W,Ning G

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Self-efficacy plays a critical role in diabetes self-care. Herein we explore factors contributing to decreased insulin therapy self-efficacy in insulin-naïve patients with type 2 diabetes mellitus (T2DM) initiating and managing insulin therapy over 36 weeks. METHODS:The study was conducted within an interna...

journal_title：Journal of diabetes

authors： Hayes RP,Curtis B,Ilag L,Nelson DR,Wong M,Funnell M

更新日期：2013-09-01 00:00:00

abstract：:Pancreatic β-cells secrete insulin when blood glucose levels become high; however, when β-cells are chronically exposed to hyperglycemia, β-cell function gradually deteriorates, which is known as β-cell glucose toxicity. In the diabetic state, nuclear expression of the pancreatic transcription factors pancreatic and d...

journal_title：Journal of diabetes

authors： Kaneto H,Matsuoka TA,Kimura T,Obata A,Shimoda M,Kamei S,Mune T,Kaku K

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:  Diabetic peripheral neuropathy (DPN) is one of the complications of type 2 diabetes mellitus (T2DM) that decreases the quality of life of T2DM patients. Very few studies have found an association between the development and progression of DPN in T2DM and angiotensin-converting enzyme (ACE) gene insertion/d...

journal_title：Journal of diabetes

authors： Mansoor Q,Javaid A,Bilal N,Ismail M

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVE:Dipeptidyl peptidase-4 (DPP-4) is responsible for degradation of glucagon-like peptide 1 (GLP-1) and gastric inhibitory polypeptide (GIP), the endogenous incretins that stimulate glucose-dependent insulin secretion. The objective was to evaluate preclinical profile of a novel DPP-4 inhibitor ZYDPLA1. METHODS...

journal_title：Journal of diabetes

authors： Jain MR,Joharapurkar AA,Bahekar RH,Patel H,Jadav P,Kshirsagar SG,Patel VJ,Patel KN,Ramanathan VK,Patel PR,Desai RC

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Metabolic syndrome (MetS) is highly prevalent worldwide, and its individual components obesity, diabetes, and hypertension have been identified as risk factors to develop severe coronavirus disease 2019 (COVID-19); however, data on MetS and clinical outcomes in COVID-19 are scarce. This study aims to determi...

journal_title：Journal of diabetes

authors： Lohia P,Kapur S,Benjaram S,Pandey A,Mir T,Seyoum B

更新日期：2021-01-16 00:00:00

abstract：:This article reviews the known pathophysiological mechanisms of comorbid gastroesophageal reflux disease (GERD) in the diabetic patient, discusses therapeutic options in care, and provides an approach to its evaluation and management. We searched for review articles published in the past 10 years through a PubMed sear...

journal_title：Journal of diabetes

authors： Punjabi P,Hira A,Prasad S,Wang X,Chokhavatia S

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Considerable uncertainty remains about obstructive lung function( OLF) in adults with metabolic syndrome (MetS). The aim of the present study was to examine pulmonary function status in adults with and without MetS. METHODS:We used data from 3109 participants aged ≥20 years of the National Health and Nutrit...

journal_title：Journal of diabetes

authors： Ford ES,Cunningham TJ,Mercado CI

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:With the current obesity epidemic, the search for effective weight loss approaches is required. In the present study, changes in weight, body composition and cardiovascular (CV) risk in response to a low-fat, reduced-energy diet (LFRE), a low-carbohydrate/high-protein diet (LCHP), or a commercially available...

journal_title：Journal of diabetes

authors： Rolland C,Hession M,Murray S,Wise A,Broom I

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:Intrahepatic expression of dipeptidyl peptidase-4 (DPP4), and circulating DPP4 (cDPP4) levels and its enzymatic activity, are increased in non-alcoholic fatty liver disease (NAFLD) and in type 2 diabetes mellitus and/or obesity. DPP4 has been implicated as a causative factor in NAFLD progression but few stud...

journal_title：Journal of diabetes

authors： Williams KH,Vieira De Ribeiro AJ,Prakoso E,Veillard AS,Shackel NA,Brooks B,Bu Y,Cavanagh E,Raleigh J,McLennan SV,McCaughan GW,Keane FM,Zekry A,Gorrell MD,Twigg SM

更新日期：2015-11-01 00:00:00

abstract：:There has been a rapid escalation of type 2 diabetes (T2D) in developing countries, with varied prevalence according to rural vs urban habitat and degree of urbanization. Some ethnic groups (eg, South Asians, other Asians, and Africans), develop diabetes a decade earlier and at a lower body mass index than Whites, hav...

journal_title：Journal of diabetes

authors： Misra A,Gopalan H,Jayawardena R,Hills AP,Soares M,Reza-Albarrán AA,Ramaiya KL

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:This meta-analysis was performed to quantitatively evaluate the dose-response association between obstructive sleep apnea (OSA) and risk of type 2 diabetes mellitus (T2DM). METHODS:PubMed, Embase, and Web of Science were searched up to 12 December 2018 for articles that assessed the OSA-T2DM association. Ra...

journal_title：Journal of diabetes

authors： Qie R,Zhang D,Liu L,Ren Y,Zhao Y,Liu D,Liu F,Chen X,Cheng C,Guo C,Li Q,Zhou Q,Tian G,Han M,Huang S,Wu X,Qin P,Li J,Cao J,Zhang M,Huang J,Lu J,Li H,Wang J,Cheng R,Hu D

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:There is little information on medication use, trends across time, and the impact of guidelines on appropriate use of antidiabetic drugs in participants with type 2 diabetes mellitus (T2DM) with chronic kidney disease (CKD). METHODS:A cross-sectional analysis of the National Health and Nutrition Examination...

journal_title：Journal of diabetes

authors： Gor D,Gerber BS,Walton SM,Lee TA,Nutescu EA,Touchette DR

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:A1c, a surrogate measure of glycemic control, is known to have a strong linear correlation with mean plasma glucose (MPG) when analyzed in populations of patients. However, clinically significant intersubject variability in this relationship exists, which suggests that A1c measurements may not reflect actual...

journal_title：Journal of diabetes

authors： Shrom D,Sarwat S,Ilag L,Bloomgarden ZT

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:The present study investigated the correlation between urinary α1 -microglobulin as a marker of tubular dysfunction and albumin excretion in children and adolescents with type 1 diabetes (T1D). METHODS:Ninety-two Egyptian patients with T1D were included in the study (mean [± SD] age 14.14 ± 5.13 years). The...

journal_title：Journal of diabetes

authors： Saif A,Soliman N

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Some reports suggest that concentrations of vitamin D are inversely, whereas concentrations of parathyroid hormone (PTH) are directly, associated with prevalent metabolic syndrome. Because of lingering uncertainty about these associations, we examined the cross-sectional associations between serum concentrat...

journal_title：Journal of diabetes

authors： Ford ES,Zhao G,Li C,Pearson WS

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:In people with chronic kidney disease (CKD), HbA1c may be a problematic measure of glycemic control. Glycated albumin and fructosamine have been proposed as better markers of hyperglycemia in CKD. In the present study we investigated associations of HbA1c, glycated albumin, and fructosamine with fasting gluc...

journal_title：Journal of diabetes

authors： Jung M,Warren B,Grams M,Kwong YD,Shafi T,Coresh J,Rebholz CM,Selvin E

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:The aim of the present study was to assess the quality of diabetes care and characteristics of the healthcare system in underdeveloped rural mountain areas of western China. METHODS:Questionnaires were used to collect data from 288 diabetic patients with a multistage cluster sampling method in Zhongjiang Co...

journal_title：Journal of diabetes

authors： Ke L,Zhang Y,Wang X,Li S,Yang W,Tong N

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Glucose excursions and hypoglycemia are associated with cardiovascular complications. However, no studies have evaluated glucose excursions and the frequency of hypoglycemia in patients treated with mitiglinide/voglibose versus glimepiride as add-on to dipeptidyl peptidase-4 inhibitor therapy. METHODS:This ...

journal_title：Journal of diabetes

authors： Fujimoto K,Shibayama Y,Yamaguchi E,Honjo S,Hamasaki A,Hamamoto Y

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Primary care physicians frequently encounter people with type 2 diabetes mellitus (T2DM) with discordant values for fasting glucose and HbA1c. The aim of this study was to identify the prevalence and characteristics of people in whom blood glucose and HbA1c did not match. METHODS:Overall, 64 553 people with...

journal_title：Journal of diabetes

authors： Rathmann W,Bongaerts B,Kostev K

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:The association between dental caries and metabolic syndrome (MetS) is inconsistent. The aim of the present study was to assess the relationship between dental caries and MetS and its components in a middle-aged Chinese population. METHODS:A cross-sectional analysis was performed of 13 998 participants aged...

journal_title：Journal of diabetes

authors： Cao X,Wang D,Zhou J,Yuan H,Chen Z

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Proprotein convertase subtilisin/kexin-type 9 (PCSK9) downregulates clearance of plasma cholesterol by liver. Its inactivation increases this clearance, reducing cardiovascular risk. However, a lack of PCSK9 could also lead to cholesterol accumulation in pancreatic islet beta cells, impairing insulin secreti...

journal_title：Journal of diabetes

authors： Mbikay M,Sirois F,Gyamera-Acheampong C,Wang GS,Rippstein P,Chen A,Mayne J,Scott FW,Chrétien M

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Limited information exists regarding the efficacy of pregabalin in Chinese patients with painful diabetic peripheral neuropathy (pDPN). METHODS:An 11-week double-blind placebo-controlled trial was performed in Chinese pDPN patients randomized (1 : 1) to 300 mg/day pregabalin or placebo. The primary outcome ...

journal_title：Journal of diabetes

authors： Mu Y,Liu X,Li Q,Chen K,Liu Y,Lv X,Xu X,Fan D,Shang N,Yang R,Pauer L,Pan C

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:The aim of the present study was to investigate whether the therapeutic efficacy of acarbose and metformin is correlated with baseline HbA1c levels in Chinese patients with newly diagnosed type 2 diabetes mellitus (T2DM). METHODS:Data for 711 subjects were retrieved from the MARCH (Metformin and AcaRbose in...

journal_title：Journal of diabetes

authors： Zhang JP,Wang N,Xing XY,Yang ZJ,Wang X,Yang WY

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:To analyze the glycemic response of Indian patients with type2 diabetes mellitus (T2DM) to combination therapy with vildagliptin and metformin and compare our data with those of clinical trials. METHODS:In a retrospective study of the hospital database, the glycemic control of 280 patients with T2DM who wer...

journal_title：Journal of diabetes

authors： Chatterjee S,Chatterjee S

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Asia is experiencing a type 2 diabetes epidemic, but prevalence differs by ethnicity and level of socioeconomic development. Singapore and Mauritius have implemented comprehensive campaigns to address this public health problem. We compared diabetes and obesity prevalence trends among Chinese and South Asian...

journal_title：Journal of diabetes

authors： Tan KHX,Barr ELM,Koshkina V,Ma S,Kowlessur S,Magliano DJ,Söderberg S,Chia KS,Zimmet P,Lim WY

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:There is a wide variety of dressings currently available for the treatment of diabetic foot ulcers (DFUs). Because of a lack of evidence from head-to-head randomized controlled trials (RCTs), the relative effects of these dressings in DFU patients remain unclear. This study compared the efficacy of nine dres...

journal_title：Journal of diabetes

authors： Zhang X,Sun D,Jiang GC

更新日期：2019-06-01 00:00:00