Review of gastroesophageal reflux disease (GERD) in the diabetic patient.

abstract：BACKGROUND:Liver X receptors (LXRs) including LXRα and LXRβ are members of the nuclear hormone receptor superfamily of ligand activated transcription factors, which serve as lipid sensors to regulate expression of genes controlling many aspects of cholesterol and fatty acid metabolism. The liver is the central organ in...

journal_title：Journal of diabetes

authors： Zhang X,Liu J,Su W,Wu J,Wang C,Kong X,Gustafsson JÅ,Ding J,Ma X,Guan Y

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Cross-sectional studies have supported the association among depression, obesity, and type 2 diabetes, but the causality remains controversial in Chinese adults. In this longitudinal study, we evaluated the synergistic effect of depression and obesity on the risk of type 2 diabetes. METHODS:This study inclu...

journal_title：Journal of diabetes

authors： Ning F,Zhang D,Xue B,Zhang L,Zhang J,Zhu Z,Zhang D,Gao R,Pang Z,Qiao Q,Qingdao Diabetes Prevention Program.

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:In people with chronic kidney disease (CKD), HbA1c may be a problematic measure of glycemic control. Glycated albumin and fructosamine have been proposed as better markers of hyperglycemia in CKD. In the present study we investigated associations of HbA1c, glycated albumin, and fructosamine with fasting gluc...

journal_title：Journal of diabetes

authors： Jung M,Warren B,Grams M,Kwong YD,Shafi T,Coresh J,Rebholz CM,Selvin E

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Atherosclerosis may be stimulated by the increased presence of insulin and tumor necrosis-factor-α (TNFα) with subsequent expression of vascular cell adhesion molecule-1 (VCAM-1). We hypothesized that extracellular signal-regulated kinase-5 (ERK5) plays an important role in insulin and TNFα-stimulated total ...

journal_title：Journal of diabetes

authors： Mackesy DZ,Goalstone ML

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Patients with diabetes mellitus (DM) are more likely to develop in-hospital complications (IHCs) than patients without DM. In addition, they have poorer outcomes after an ischemic stroke (IS). Our goal was to evaluate whether the increase in risk for the development of IHCs in patients with IS is due to DM p...

journal_title：Journal of diabetes

authors： Cruz-Herranz A,Fuentes B,Martínez-Sánchez P,Ruiz-Ares G,Lara-Lara M,Sanz-Cuesta B,Díez-Tejedor E

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Glucose excursions and hypoglycemia are associated with cardiovascular complications. However, no studies have evaluated glucose excursions and the frequency of hypoglycemia in patients treated with mitiglinide/voglibose versus glimepiride as add-on to dipeptidyl peptidase-4 inhibitor therapy. METHODS:This ...

journal_title：Journal of diabetes

authors： Fujimoto K,Shibayama Y,Yamaguchi E,Honjo S,Hamasaki A,Hamamoto Y

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Insulin therapy should be strongly considered in newly diagnosed type 2 diabetic (T2D) patients with severe hyperglycemia. However, whether insulin be continued or patients switched to an oral antidiabetic drug (OAD) after short-term intensive insulin therapy (ITT) is not clear. METHODS:After ITT for 10-14 ...

journal_title：Journal of diabetes

authors： Cheng Q,Yang S,Zhao C,Wang Z,Feng Z,Li R,Ye P,Zhang S,Deng H,Zhou B,Long J,Gong L,Qing H,Luo C,Li Q

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:In addition to its glucoregulatory actions, exendin-4, a stable glucagon-like peptide-1 receptor agonist, exhibits protective effects in the pancreas and anti-obesity effects. Suitable combination treatment with other anti-obesity or pancreas protective agents would be an effective approach to optimize these...

journal_title：Journal of diabetes

authors： Patel V,Joharapurkar A,Gandhi T,Patel K,Dhanesha N,Kshirsagar S,Dhote V,Detroja J,Bahekar R,Jain M

更新日期：2013-06-01 00:00:00

abstract：:Glucagon-like peptide-1 (GLP-1) is the primary incretin hormone secreted from the intestine upon uptake of food to stimulate insulin secretion from pancreatic β-cells. GLP-1 exerts its effects by binding to its G-protein coupled receptors and subsequently activating adenylate cyclase, leading to generation of cyclic a...

journal_title：Journal of diabetes

authors： Ma X,Guan Y,Hua X

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Erectile dysfunction (ED) is a prevalent complication of diabetes, and oxidative stress is an important feature of diabetic ED. Oxidative stress-induced damage plays a pivotal role in the development of tissue alterations. However, the deleterious effects of oxidative stress in the corpus cavernosum with the...

journal_title：Journal of diabetes

authors： Castela A,Gomes P,Domingues VF,Paíga P,Costa R,Vendeira P,Costa C

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Currently, there is no consensus regarding the medical treatment of chronic Charcot neuroarthropathy (CN) of foot, except for effective off-loading. Because tarsal bones are predominantly trabecular, teriparatide may improve the macroarchitecture of foot bones in chronic CN. METHODS:People with diabetes and...

journal_title：Journal of diabetes

authors： Rastogi A,Hajela A,Prakash M,Khandelwal N,Kumar R,Bhattacharya A,Mittal BR,Bhansali A,Armstrong DG

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Convincing evidence indicates that the consumption of inulin-type fructans, inulin, and oligofructose has beneficial effects on blood glucose changes in animal models, although data in humans have been considered equivocal. As such, a systematic review of available literature on humans was conducted to evalu...

journal_title：Journal of diabetes

authors： Bonsu NK,Johnson CS,McLeod KM

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Type 1 diabetes (T1D) is an autoimmune disease in which pancreatic β-cells are destroyed by infiltrating immune cells. Bilateral cooperation of pancreatic β-cells and immune cells has been proposed in the progression of T1D, but as yet no systems study has investigated this possibility. The aims of the study...

journal_title：Journal of diabetes

authors： Safari-Alighiarloo N,Taghizadeh M,Tabatabaei SM,Shahsavari S,Namaki S,Khodakarim S,Rezaei-Tavirani M

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Asia is experiencing a type 2 diabetes epidemic, but prevalence differs by ethnicity and level of socioeconomic development. Singapore and Mauritius have implemented comprehensive campaigns to address this public health problem. We compared diabetes and obesity prevalence trends among Chinese and South Asian...

journal_title：Journal of diabetes

authors： Tan KHX,Barr ELM,Koshkina V,Ma S,Kowlessur S,Magliano DJ,Söderberg S,Chia KS,Zimmet P,Lim WY

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Genome-wide association studies (GWAS) have identified several genetic variants affecting gestational glucose metabolism. However, information regarding their known associations with gestational diabetes mellitus (GDM) risk remains scarce. METHODS:This study examined the associations of 12 gestational gluco...

journal_title：Journal of diabetes

authors： Xie K,Zhang Y,Wen J,Chen T,Kong J,Zhang J,Wu X,Hu C,Xu B,Ji C,Guo X,Wu J

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:This meta-analysis was performed to quantitatively evaluate the dose-response association between obstructive sleep apnea (OSA) and risk of type 2 diabetes mellitus (T2DM). METHODS:PubMed, Embase, and Web of Science were searched up to 12 December 2018 for articles that assessed the OSA-T2DM association. Ra...

journal_title：Journal of diabetes

authors： Qie R,Zhang D,Liu L,Ren Y,Zhao Y,Liu D,Liu F,Chen X,Cheng C,Guo C,Li Q,Zhou Q,Tian G,Han M,Huang S,Wu X,Qin P,Li J,Cao J,Zhang M,Huang J,Lu J,Li H,Wang J,Cheng R,Hu D

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Elevated blood or urinary concentrations of endocrine-disrupting chemicals (EDCs) may be related to increased risk of type 2 diabetes (T2D). The aim of the present study was to assess the role of EDCs in affecting risk of T2D and related metabolic traits. METHODS:MEDLINE was searched for cross-sectional and...

journal_title：Journal of diabetes

authors： Song Y,Chou EL,Baecker A,You NC,Song Y,Sun Q,Liu S

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Few studies have focused on postprandial incretin responses to different carbohydrate meals. Therefore, we designed a study to compare the different effects of two carbohydrates (75 g oral glucose, a monosaccharide and 100 g standard noodle, a polysaccharide, with 75 g carbohydrates equivalently) on postpran...

journal_title：Journal of diabetes

authors： Deng Y,Zhang Y,Zheng S,Hong J,Wang C,Liu T,Sun Z,Gu W,Gu Y,Shi J,Yao S,Wang W,Ning G

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Although diabetes is associated with ethnicity and worse cardiac surgery outcomes, no research has been done to study the effect of both diabetes and ethnicity on cardiac surgery outcomes in a multiethnic Southeast Asian cohort. Hence, this study aimed to delineate the association of ethnicity on outcomes af...

journal_title：Journal of diabetes

authors： Moorthy V,Liu W,Chan SP,Chew STH,Ti LK

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:To evaluate the association between thyroid autoimmunity and psychiatric disorders (depression, anxiety, eating disorder, schizophrenia or attention-deficit/hyperactivity disorder) among adolescents and young adults with type 1 diabetes (11-25 years). METHODS:We compared 9368 type 1 diabetes patients with t...

journal_title：Journal of diabetes

authors： Eckert A,Galler A,Papsch M,Hess M,Holder M,Döing C,Bierkamp-Christophersen D,Hammer E,Pappa A,Lanzinger S

更新日期：2020-12-16 00:00:00

abstract：BACKGROUND:  Diabetic peripheral neuropathy (DPN) is one of the complications of type 2 diabetes mellitus (T2DM) that decreases the quality of life of T2DM patients. Very few studies have found an association between the development and progression of DPN in T2DM and angiotensin-converting enzyme (ACE) gene insertion/d...

journal_title：Journal of diabetes

authors： Mansoor Q,Javaid A,Bilal N,Ismail M

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:To address the prognostic value of combining tubular basement membrane (TBM) and glomerular basement membrane (GBM) thickness in diabetic nephropathy (DN). METHODS:This retrospective study enrolled 110 patients with type 2 diabetes and biopsy-proven DN from 2011 to 2018. The pathological findings were confi...

journal_title：Journal of diabetes

authors： Zhao L,Zhang J,Lei S,Ren H,Zou Y,Bai L,Zhang R,Xu H,Li L,Zhao Y,Cooper ME,Tong N,Zhang J,Liu F

更新日期：2020-12-22 00:00:00

abstract：BACKGROUND:Glucagon-like peptide-1 (GLP-1) and its stable analogue exendin-4 maintain glucose homeostasis by modulating insulin secretion from pancreatic β-cells and controlling hepatic glucose output. Glucokinase (GK), by catalysing the first step in glycolysis, plays an important role in glucose-stimulated insulin se...

journal_title：Journal of diabetes

authors： Dhanesha N,Joharapurkar A,Shah G,Dhote V,Kshirsagar S,Bahekar R,Jain M

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Although niacin often has beneficial effects on the lipoprotein profile, flushing is an untoward effect associated with its use. Aspirin can only reduce the flushing response by 30-40%. Thus, the aim of the present study was to investigate the mechanisms of niacin-induced flushing, with and without aspirin, ...

journal_title：Journal of diabetes

authors： Parson HK,Harati H,Cooper D,Vinik AI

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:The effect of postload glucose spikes (PGS), the difference between 2 hour post-load plasma glucose (2hPLPG) and fasting plasma glucose (FPG), on post-myocardial infarction (post-MI) prognosis in nondiabetic patients is unexplored. METHODS:This is a retrospective cohort analysis of 847 nondiabetic post-MI s...

journal_title：Journal of diabetes

authors： Chattopadhyay S,George A,John J,Sathyapalan T

更新日期：2021-03-01 00:00:00

abstract：BACKGROUND:Self-efficacy plays a critical role in diabetes self-care. Herein we explore factors contributing to decreased insulin therapy self-efficacy in insulin-naïve patients with type 2 diabetes mellitus (T2DM) initiating and managing insulin therapy over 36 weeks. METHODS:The study was conducted within an interna...

journal_title：Journal of diabetes

authors： Hayes RP,Curtis B,Ilag L,Nelson DR,Wong M,Funnell M

更新日期：2013-09-01 00:00:00

abstract：:Highlights A large retrospective study indicates no association between GDM and most types of cancer; this is in contrast to a few smaller studies that have suggested an association with cancer. An increased risk of thyroid cancer in mothers with GDM was demonstrated. While this risk requires further investigation, it...

journal_title：Journal of diabetes

authors： Pace R,Rahme E,Dasgupta K

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:The aim of the present study was to develop a simple nomogram that can be used to predict the risk of diabetes mellitus (DM) in the asymptomatic non-diabetic subjects based on non-laboratory- and laboratory-based risk algorithms. METHODS:Anthropometric data, plasma fasting glucose, full lipid profile, exerc...

journal_title：Journal of diabetes

authors： Wong CK,Siu SC,Wan EY,Jiao FF,Yu EY,Fung CS,Wong KW,Leung AY,Lam CL

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:To analyze the glycemic response of Indian patients with type2 diabetes mellitus (T2DM) to combination therapy with vildagliptin and metformin and compare our data with those of clinical trials. METHODS:In a retrospective study of the hospital database, the glycemic control of 280 patients with T2DM who wer...

journal_title：Journal of diabetes

authors： Chatterjee S,Chatterjee S

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Cross-sectional studies have reported a close association between serum lipopolysaccharide-binding protein (LBP) and many metabolic disorders. However, no longitudinal study has explored the relationship between LBP and type 2 diabetes mellitus (T2DM). The aim of the present study was to investigate the asso...

journal_title：Journal of diabetes

authors： Zhou H,Hu J,Zhu Q,Yang S,Zhang Y,Gao R,Liu L,Wang Y,Zhen Q,Lv Q,Li Q

更新日期：2016-03-01 00:00:00