Preparation and characterization of Fe3O4 particles with novel nanosheets morphology and magnetochromatic property by a modified solvothermal method.

abstract：:Bezafibrate (BzF) is eliminated by renal excretion and dosage must be reduced in patients with chronic kidney disease (CKD). There is a concern that BzF causes a further deterioration in renal function in patients with CKD. This study assessed whether BzF discontinuation or dose reduction in CKD patients improves rena...

journal_title：Scientific reports

authors： Zingerman B,Ziv D,Feder Krengel N,Korzets A,Matok I

更新日期：2020-11-13 00:00:00

abstract：:Lipid mediators play pivotal roles in colorectal cancer and colitis, but only a limited member of the phospholipase A2 (PLA2) subtypes, which lie upstream of various lipid mediators, have been implicated in the positive or negative regulation of these diseases. Clinical and biochemical evidence suggests that secreted ...

journal_title：Scientific reports

authors： Murase R,Taketomi Y,Miki Y,Nishito Y,Saito M,Fukami K,Yamamoto K,Murakami M

更新日期：2017-09-25 00:00:00

abstract：:Developed through evolution, brain neural system self-organizes into an economical and dynamic network structure with the modulation of repetitive neuronal firing activities through synaptic plasticity. These highly variable electric activities inevitably produce a spontaneous magnetic field, which also significantly ...

journal_title：Scientific reports

authors： Wang R,Fan Y,Wu Y

更新日期：2019-07-04 00:00:00

abstract：:Baeyer-Villiger monooxygenases (BVMOs) are able to catalyze regiospecific Baeyer-Villiger oxygenation of a variety of cyclic and linear ketones to generate the corresponding lactones and esters, respectively. However, the enzymes are usually difficult to express in a functional form in microbial cells and are rather u...

journal_title：Scientific reports

authors： Seo JH,Kim HH,Jeon EY,Song YH,Shin CS,Park JB

更新日期：2016-06-17 00:00:00

abstract：:The pharmacokinetic compatibility of short-acting CDRI candidate antimalarial trioxane derivative, 99-411, was tested with long-acting prescription antimalarials, lumefantrine and piperaquine. LC-ESI-MS/MS methods were validated for simultaneous bioanalysis of lumefantrine and 99-411 and of piperaquine and 99-411 comb...

journal_title：Scientific reports

authors： Taneja I,Raju KS,Singh SP,Wahajuddin M

更新日期：2015-11-25 00:00:00

abstract：:Most bacterial cells are stressed, and as a result, some become tolerant to antibiotics by entering a dormant state known as persistence. The key intracellular metabolite that has been linked to this persister state is guanosine tetraphosphate (ppGpp), the alarmone that was first linked to nutrient stress. In Escheric...

journal_title：Scientific reports

authors： Chowdhury N,Kwan BW,Wood TK

更新日期：2016-02-03 00:00:00

abstract：:The discovery of single-phase multiferroic materials and the understanding of coupling mechanisms between their spin and polarization is important from the point of view of next generation logic and memory devices. Herein we report the fabrication, dielectric, ferroelectric, piezo-response force microscopy, and magnet...

journal_title：Scientific reports

authors： Mishra KK,Instan AA,Kumari S,Scott JF,Katiyar RS

更新日期：2020-02-19 00:00:00

abstract：:The Alzheimer's disease pathology is associated with accumulation of intracellular neurofibrillary tangles and extracellular senile plaques. The formation of initial nucleus triggers conformational changes in Tau and leads to its deposition. Hence, there is a need to eliminate these toxic proteins for proper functioni...

journal_title：Scientific reports

authors： Gorantla NV,Das R,Chidambaram H,Dubey T,Mulani FA,Thulasiram HV,Chinnathambi S

更新日期：2020-03-04 00:00:00

abstract：:The cytoskeletal filament vimentin is inherent to the endothelial phenotype and is critical for the proper function of endothelial cells in adult mice. It is unclear, however, if the presence of vimentin is necessary during differentiation to the endothelial phenotype. Here we evaluated gene and protein expression of ...

journal_title：Scientific reports

authors： Boraas LC,Ahsan T

更新日期：2016-08-02 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...

journal_title：Scientific reports

authors： Carregari VC,Rosa-Fernandes L,Baldasso P,Bydlowski SP,Marangoni S,Larsen MR,Palmisano G

更新日期：2018-10-23 00:00:00

abstract：:In plants and parenchymatous brown algae the body arises through the activity of an apical meristem (a niche of cells or a single cell). The meristem produces lateral organs in specific patterns, referred to as phyllotaxis. In plants, two different control mechanisms have been proposed: one is position-dependent and r...

journal_title：Scientific reports

authors： Linardić M,Braybrook SA

更新日期：2017-10-24 00:00:00

abstract：:The study of postsynaptic excitation to inhibition (E/I ratio) imbalances in human brain diseases, is a highly relevant functional measurement poorly investigated due to postmortem degradation of synaptic receptors. We show that near-simultaneous recording of microtransplanted synaptic receptors after simulated morgue...

journal_title：Scientific reports

authors： Scaduto P,Sequeira A,Vawter MP,Bunney W,Limon A

更新日期：2020-05-25 00:00:00

abstract：:We describe the development and clinical evaluation of an automated smartphone-linked sensor capable of chemical-free, quantitative measurement of hemoglobin concentration ([Hb]) in whole blood samples. We have demonstrated that our sensor could analyze an unprocessed blood specimen with a mean processing time of <8 s...

journal_title：Scientific reports

authors： Lee J,Song J,Choi JH,Kim S,Kim U,Nguyen VT,Lee JS,Joo C

更新日期：2020-05-25 00:00:00

abstract：:Post-operative pancreatic fistula (POPF) following pancreatic resection is a life-threatening surgical complication. Cell sheets were prepared and harvested using temperature-responsive culture dishes and transplanted as patches to seal POPF. Two different mesenchymal stem cell (MSC) sheets were compared in terms of t...

journal_title：Scientific reports

authors： Kim SR,Yi HJ,Lee YN,Park JY,Hoffman RM,Okano T,Shim IK,Kim SC

更新日期：2018-01-10 00:00:00

abstract：:Microbial survival in dynamic environments requires the ability to successfully respond to abrupt changes in osmolarity. The mechanosensitive channel of large conductance (MscL) is a ubiquitous channel that facilitates the survival of bacteria and archaea under severe osmotic downshock conditions by relieving excess t...

journal_title：Scientific reports

authors： Herrera N,Maksaev G,Haswell ES,Rees DC

更新日期：2018-10-01 00:00:00

abstract：:Uncertainty in the form of risk or ambiguity can arise from the interaction with nature and other players, while strategic uncertainty arises only in interactions with others. Here, we systematically compare binary decisions between a safe option and a potentially higher paying but uncertain option in four experimenta...

journal_title：Scientific reports

authors： Chierchia G,Nagel R,Coricelli G

更新日期：2018-02-23 00:00:00

abstract：:The Iberian Mediterranean Basin is home to one of the largest groups of prehistoric rock art sites in Europe. Despite the cultural relevance of prehistoric Spanish Levantine rock art, pigment composition remains partially unknown, and the nature of the binders used for painting has yet to be disclosed. In this work, w...

journal_title：Scientific reports

authors： Roldán C,Murcia-Mascarós S,López-Montalvo E,Vilanova C,Porcar M

更新日期：2018-07-03 00:00:00

abstract：:SOX7 as a tumor suppressor belongs to the SOX F gene subfamily and is associated with a variety of human cancers, including breast cancer, but the mechanisms involved are largely unclear. In the current study, we investigated the interactions between SOX7 and AXIN2 in their co-regulation on the Wnt/β-catenin signal pa...

journal_title：Scientific reports

authors： Liu H,Mastriani E,Yan ZQ,Yin SY,Zeng Z,Wang H,Li QH,Liu HY,Wang X,Bao HX,Zhou YJ,Kou JJ,Li D,Li T,Liu J,Liu Y,Yin L,Qiu L,Gong L,Liu SL

更新日期：2016-05-18 00:00:00

abstract：:Recent data suggest that tumor laterality and mucinous histology may be clinically relevant. We investigated how both variables impact on the prognosis and the response to therapies in a large population-based cohort of cancer patients. Incidence data, clinical and pathological features, and outcome were systematicall...

journal_title：Scientific reports

authors： Negri F,De Giorgi A,Gilli A,Azzoni C,Bottarelli L,Gnetti L,Goldoni M,Manotti L,Sgargi P,Michiara M,Leonardi F,Rindi G,Cascinu S,Silini EM

更新日期：2019-03-06 00:00:00

abstract：:Adipose tissue plays a major role in regulating whole-body insulin sensitivity and energy metabolism. To accommodate surplus energy, the tissue rapidly expands by increasing adipose cell size (hypertrophy) and cell number (hyperplasia). Previous studies have shown that enlarged, hypertrophic adipocytes are less respon...

journal_title：Scientific reports

authors： Hansson B,Morén B,Fryklund C,Vliex L,Wasserstrom S,Albinsson S,Berger K,Stenkula KG

更新日期：2019-09-10 00:00:00

abstract：:In situ tissue engineering within a stroke cavity is gradually emerging as a novel therapeutic paradigm. Considering the varied lesion topology within each subject, the placement and distribution of cells within the lesion cavity is challenging. The use of multiple cell types to reconstruct damaged tissue illustrates ...

journal_title：Scientific reports

authors： Nicholls FJ,Ling W,Ferrauto G,Aime S,Modo M

更新日期：2015-09-30 00:00:00

abstract：:Singular beams which possess helical phase wavefront or spatially inhomogeneous polarization provide new freedom for optical field manipulation. However, conventional schemes to produce the singular beams have difficulty in realizing the flexible switch between different singular beams. In this work, we have experimen...

journal_title：Scientific reports

authors： He Y,Li Y,Liu J,Zhang X,Cai Y,Chen Y,Chen S,Fan D

更新日期：2017-07-28 00:00:00

abstract：:Recent use of the CRISPR/Cas9 system has dramatically reduced the time required to produce mutant mice, but the involvement of a time-consuming microinjection step still hampers its application for high-throughput genetic analysis. Here we developed a simple, highly efficient, and large-scale genome editing method, in...

journal_title：Scientific reports

authors： Hashimoto M,Takemoto T

更新日期：2015-06-11 00:00:00

abstract：:Due to the increasing concern of using smallpox virus as biological weapons for terrorist attack, there is renewed interest in studying the pathogenesis of human smallpox and development of new therapies. Animal models are highly demanded for efficacy and safety examination of new vaccines and therapeutic drugs. Here,...

journal_title：Scientific reports

authors： Liu Q,Fan C,Zhou S,Guo Y,Zuo Q,Ma J,Liu S,Wu X,Peng Z,Fan T,Guo C,Shen Y,Huang W,Li B,He Z,Wang Y

更新日期：2015-08-03 00:00:00

abstract：:Marigold (Tagetes erecta L.) is an important ornamental plant with a wide variety of flower colors. Despite its economic value, few biochemical and molecular studies have explored the generation of flower color in this species. To study the mechanism underlying marigold petal color, we performed a metabolite analysis ...

journal_title：Scientific reports

authors： Zhang H,Zhang S,Zhang H,Chen X,Liang F,Qin H,Zhang Y,Cong R,Xin H,Zhang Z

更新日期：2020-10-08 00:00:00

abstract：:Endoluminal surgery for the treatment of colorectal neoplasia is typically carried out using electrocautery tools which imply limited precision and the risk of harm through collateral thermal damage to the adjacent healthy tissue. As a potential alternative, we present the successful colonic epithelial laser ablation ...

journal_title：Scientific reports

authors： Beck RJ,Bitharas I,Hand DP,Maisey T,Moore AJ,Shires M,Thomson RR,West NP,Jayne DG,Shephard JD

更新日期：2020-11-20 00:00:00

abstract：:We aimed to develop and validate a multiparametric MR radiomics model using conventional, diffusion-, and perfusion-weighted MR imaging for better prognostication in patients with newly diagnosed glioblastoma. A total of 216 patients with newly diagnosed glioblastoma were enrolled from two tertiary medical centers and...

journal_title：Scientific reports

authors： Park JE,Kim HS,Jo Y,Yoo RE,Choi SH,Nam SJ,Kim JH

更新日期：2020-03-06 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Xue Q,Li X,Gu Y,Wang X,Wang M,Tian J,Duan X,Gao H,Ji X,Yan X,Dong W,Fang Q,Zhang X

更新日期：2020-05-08 00:00:00

abstract：:The β5 subunit of the proteasome has been shown in worms and in human cell lines to be regulatory. In these models, β5 overexpression results in upregulation of the entire proteasome complex which is sufficient to increase proteotoxic stress resistance, improve metabolic parameters, and increase longevity. However, fu...

journal_title：Scientific reports

authors： Nguyen NN,Rana A,Goldman C,Moore R,Tai J,Hong Y,Shen J,Walker DW,Hur JH

更新日期：2019-02-28 00:00:00

abstract：:Extracellular matrix (ECM) mechanical properties upregulate cancer invasion, cell contractility, and focal adhesion formation. Alteration in energy metabolism is a known characteristic of cancer cells (i.e., Warburg effect) and modulates cell invasion. There is little evidence to show if collagen density can alter can...

journal_title：Scientific reports

authors： Mah EJ,Lefebvre AEYT,McGahey GE,Yee AF,Digman MA

更新日期：2018-11-20 00:00:00