Abstract：
:Small intestine bacterial overgrowth (SIBO) occurs when colonic quantities of commensal bacteria are present in the small bowel. SIBO is associated with conditions of disrupted gastrointestinal (GI) motility leading to stasis of luminal contents. Recent data show that SIBO is also found in children living in unsanitary conditions who do not have access to clean water. SIBO leads to impaired micronutrient absorption and increased GI permeability, both of which may contribute to growth stunting in children. SIBO also disrupts mucosal immunity and has been implicated in oral vaccination underperformance and the development of celiac disease. SIBO in the setting of the impoverished human habitats may be an under-recognized cause of pediatric morbidity and mortality in the developing world.
journal_name
Trends Mol Medjournal_title
Trends in molecular medicineauthors
Donowitz JR,Petri WA Jrdoi
10.1016/j.molmed.2014.11.001subject
Has Abstractpub_date
2015-01-01 00:00:00pages
6-15issue
1eissn
1471-4914issn
1471-499Xpii
S1471-4914(14)00193-2journal_volume
21pub_type
杂志文章abstract：:Near-infrared fluorescence (NIRF) imaging promises to improve cancer imaging and management; advances in nanomaterials allow scientists to combine new nanoparticles with NIRF imaging techniques, thereby fulfilling this promise. Here, we present a synopsis of current developments in NIRF nanoprobes, their use in imagin...
journal_title：Trends in molecular medicine
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abstract：:Autosomal dominant polycystic kidney disease (ADPKD) is the most common potentially lethal monogenic disorder, with more than 12 million cases worldwide. The two causative genes for ADPKD, PKD1 and PKD2, encode protein products polycystin-1 (PC1) and polycystin-2 (PC2 or TRPP2), respectively. Recent data have shed lig...
journal_title：Trends in molecular medicine
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journal_title：Trends in molecular medicine
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journal_title：Trends in molecular medicine
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更新日期：2014-10-01 00:00:00
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更新日期：2010-07-01 00:00:00
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journal_title：Trends in molecular medicine
pub_type： 杂志文章,评审
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更新日期：2004-12-01 00:00:00
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journal_title：Trends in molecular medicine
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更新日期：2001-07-01 00:00:00
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journal_title：Trends in molecular medicine
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journal_title：Trends in molecular medicine
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更新日期：2005-03-01 00:00:00
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journal_title：Trends in molecular medicine
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journal_title：Trends in molecular medicine
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journal_title：Trends in molecular medicine
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journal_title：Trends in molecular medicine
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abstract：:What biological factors account for resilience to pain or to behavioral stress? Here, we discuss examples of cellular and molecular mechanisms within disparate parts of the nervous system as contributors to such resilience. In some especially well-studied humans, it is possible to identify particular neuronal cell typ...
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