Abstract:
:Sperm production is regulated by inhibin. Inhibin secretion may be controlled by the number of ejaculations. The more the number of ejaculations, the less the inhibin in blood and the more the production of spermatozoa.
journal_name
Med Hypothesesjournal_title
Medical hypothesesauthors
Skandhan KPdoi
10.1016/0306-9877(89)90089-3subject
Has Abstractpub_date
1989-10-01 00:00:00pages
81-2issue
2eissn
0306-9877issn
1532-2777pii
0306-9877(89)90089-3journal_volume
30pub_type
杂志文章abstract::No single dietary factor or ingested substance has been implicated in the aetiology of oesophageal carcinoma especially in high-risk areas of the world. Although not well defined, there is heavy consumption of tannin-rich foods, particularly sorghum, by populations at high risk for carcinoma. The carcinogenic properti...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/0306-9877(88)90060-6
更新日期:1988-06-01 00:00:00
abstract::In an effort to develop a method to ascertain whether ancient physicians used certain drugs because of their efficacy or for other reasons (random process, tradition, etc.), the authors have devised a statistical test (Efficacy Quotient-EQ) to evaluate ancient therapeutic data quantitatively. They have applied the Eff...
journal_title:Medical hypotheses
pub_type: 历史文章,杂志文章
doi:10.1016/s0306-9877(98)90057-3
更新日期:1998-10-01 00:00:00
abstract::Ontogenesis might be considered as the development of phylogenetically consequent genic systems that mainly imply: homoeotic genes and ras protooncogene in segmentation; ras and myc protooncogenes in gastrulation; ras, myc and other nuclear protooncogenes in organogenesis; ras myc, other nuclear and cytomembrane proto...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/0306-9877(89)90033-9
更新日期:1989-12-01 00:00:00
abstract::Dental tissues contains stem cells or progenitors that have high proliferative capacity, are clonogenic in vitro and demonstrate the ability to differentiate to multiple type cells involving neurons, bone, cartilage, fat and smooth muscle. Numerous experiments have demonstrated that the multipotent stem cells are not ...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2013.07.032
更新日期:2013-10-01 00:00:00
abstract::Being born in the winter and spring significantly increases one's risk for developing schizophrenia. This birth seasonality may account for as many as 10% of all cases of schizophrenia. Maternal third trimester infections or vitamin D deficiencies are hypothesized to be the most likely cause and can account for many o...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2011.02.019
更新日期:2011-06-01 00:00:00
abstract::There are large amounts of zinc in muscle and zinc ions can enhance the degree of muscle contraction in response to direct stimulation while at the same time inhibiting neuromuscular transmission. The opposites of these effects would lead to myotonia and muscle weakness. There are many parallels between the non-muscul...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/0306-9877(80)90052-3
更新日期:1980-04-01 00:00:00
abstract::Abdominal aortic aneurysms (AAAs) have traditionally been attributed to atherosclerosis, although there is increasing epidemiological, biochemical and genetic evidence that aneurysmal arterial disease is different from occlusive atherosclerosis. One of the most consistent biochemical findings in the aneurysmal aorta i...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/0306-9877(95)90193-0
更新日期:1995-07-01 00:00:00
abstract::The staggering number of publications featuring the use of stem cells has revolutionized regenerative medicine research. Preclinical studies indicate that allogeneic human mesenchymal stem cells (MSCs) may be useful for the treatment of several clinical disorders, including sepsis, acute renal failure, acute myocardia...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2011.01.010
更新日期:2011-04-01 00:00:00
abstract::A new three barrier, four compartment model for sodium transport in high resistance urinary epithelia is presented. This model provides a unified and simplified mechanistic explanation for sodium transport and its quantitative regulation. Sodium enters the epithelial cell by passive diffusion. Active extrusion occurs ...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/0306-9877(76)90050-5
更新日期:1976-05-01 00:00:00
abstract::Incretin hormones have trophic effects on beta cell function that can aid prevention and treatment of diabetes. cAMP is the primary mediator of these effects, and has been shown to potentiate glucose-stimulated insulin secretion, promote proper beta cells differentiation by increasing expression of the crucial transcr...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2004.04.031
更新日期:2006-01-01 00:00:00
abstract::Although the classical ideal is that scientific theories are evaluated by a careful teasing-out of their internal logic and external implications, and checking whether these deductions and predictions are in-line-with old and new observations; the fact that so many vague, dumb or incoherent scientific theories are app...
journal_title:Medical hypotheses
pub_type: 社论
doi:10.1016/j.mehy.2008.05.018
更新日期:2008-09-01 00:00:00
abstract::High doses of oestrogens in the dog and ferret cause myeloid hyperplasia in the bone marrow superseded by hypoplasia affecting all cell lines. In the peripheral blood after an initial leucocytosis, there is thrombocytopenia, anaemia and leucopenia. These effects, which are ultimately lethal, do not occur in cats, rats...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/0306-9877(85)90070-2
更新日期:1985-02-01 00:00:00
abstract::Cholesterol efflux from macrophage foam cells, the initial step of reverse cholesterol transport, is assumed to be the most relevant step with respect to atherosclerosis. As one of the ATP-binding cassette transporter (ABC) family members, ABCG1 plays a critical role in the process of cholesterol efflux. It has been r...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2006.06.042
更新日期:2007-01-01 00:00:00
abstract:AIMS:To investigate the role of urinary BK polyoma virus (BKPyV) in the pathophysiology and prognosis of patients with painful bladder syndrome/interstitial cystitis (PBS/IC). METHODS:Urine samples were collected from 15 patients with PBS/IC and 8 control patients (with urolithiasis, overactive bladder and benign pros...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2014.06.004
更新日期:2014-09-01 00:00:00
abstract::Chloroquine is one of the antimalaria drugs, also used to treat rheumatoid arthritis and systemic lupus erythematosus (SLE). Although well tolerated in most individuals, it was suggested that chloroquine can exert a profound influence on renal function, especially in individuals with compromised body fluid status. How...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2006.06.012
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:Operative risk prediction systems (logistic EuroSCORE I, EuroSCORE II and STS Score) are employed together with multidisciplinary discussion to contraindicate conventional surgery in patients with valvular heart disease and propose the employment of alternative transcatheter procedures. The EuroSCORE I has b...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2015.01.043
更新日期:2015-05-01 00:00:00
abstract::We describe here a new technique for analyzing human growth curves using a first order kinetic representation. Plotting in ([h infinity-ht)/h infinity] vs time (where h infinity and ht represent the final and instantaneous heights) transforms growth curves into 3 linear phases and 2 interphases. These growth parameter...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/0306-9877(85)90073-8
更新日期:1985-02-01 00:00:00
abstract::Jet lag is a travel-induced circadian rhythm phenomenon that afflicts healthy individuals following long- distance flights through several time zones. The typical jet-lag manifestations - insomnia during local sleep time, day fatigue, reduced concentration, irritability, and exhaustion with mild depression - are attri...
journal_title:Medical hypotheses
pub_type: 杂志文章,评审
doi:10.1054/mehy.2000.1094
更新日期:2001-01-01 00:00:00
abstract::Many of the movement disorders seen in psychiatric patients are determined, in large part, by the dynamic balance of dopamine and acetylcholine in the basal ganglia. Gamma aminobutyric acid has effects on various neurotransmitters in the brain including dopamine and acetylcholine and is therefore relevant to a discuss...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/0306-9877(88)90008-4
更新日期:1988-12-01 00:00:00
abstract::Metabolic syndrome (MetS) is a complex and heterogeneous disease characterized by central obesity, impaired glucose metabolism, dyslipidemia, arterial hypertension, insulin resistance and high-sensitivity C-reactive protein. In 2006, a neurotrophic hypothesis of the etiopathogenesis of MetS was launched. This hypothes...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2013.07.018
更新日期:2013-10-01 00:00:00
abstract::Chronic stresses can induce physiological and psychological changes and result in stress-related neuropsychiatry, sometimes they may also contribute to hypersensitivity to pain known as stress-induced hyperalgesia (SIH). Recently it was found that GABAergic disinhibition is closely related to morphine and chronic infl...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2014.10.008
更新日期:2014-12-01 00:00:00
abstract::The prognosis of esophageal cancer (EC) remains poor, lymph node metastasis is one of the most important factors for determining the prognosis of patients with EC. Extensive lymph node dissection has long been considered as the favorable procedure to achieve an accurate pathologic staging and a better prognosis. Howev...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2010.01.017
更新日期:2010-06-01 00:00:00
abstract::Mood expressions encompassing positive scales like "activity, elation, contemplation, calmness" and negative scales like "anger, excitement, depression, fatigue" were applied for introducing a new tool to assess the effects of acupuncture on brain structures. Traditional acupuncture points defined in the literature fo...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2015.05.013
更新日期:2015-09-01 00:00:00
abstract::Synthetic and semisynthetic fabrics generate electrostatic potentials on the surface of the skin. The author suggests that the effects of electrostatic potentials on physical and psychological condition are mediated by acupuncture points. The author further suggests that electrostatic charges on the surface of the ski...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1054/mehy.1999.0854
更新日期:2000-03-01 00:00:00
abstract::Epidemiological studies highlight the negative correlation between vitamin D levels and the incidence of many non-skeletal diseases including inflammatory diseases, cancer, and metabolic and neurological disorders. However, most randomized controlled trials (RCTs) with oral vitamin D supplementation give mixed results...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2019.109417
更新日期:2020-01-01 00:00:00
abstract::Geographic patterns with diminishing rates from north to south toward the equator have been described for a number of diseases, putatively related largely to "western" lifestyle. Among these the inflammatory bowel diseases; Crohn's (CD) and Ulcerative colitis (UC) have been prominent in sharing distributions with a nu...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2016.10.001
更新日期:2016-11-01 00:00:00
abstract::NETosis, being an alternative form of cell death is the creation of web-like chromatin decondensates by suitably primed neutrophils as a response to stimulus aimed at containing and eliminating the same. In certain situations, it causes more harm than benefit in the form of bystander damage directly or via activation ...
journal_title:Medical hypotheses
pub_type: 信件
doi:10.1016/j.mehy.2020.109968
更新日期:2020-11-01 00:00:00
abstract::The globally increasing incidences of Type 1 diabetes (T1DM) and Type 2 diabetes (T2DM) can have a common background. If challenged by the contemporary high level of nutritional glucose stimulation, the β-cells in genetically predisposed individuals are at risk for damage which can lead to the diseases. The fat to car...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2019.02.027
更新日期:2019-04-01 00:00:00
abstract::Acute stroke, including acute ischemic stroke (AIS) and acute hemorrhagic stroke, (AHS) is a common medical problem with particular relevance to the demographic changes in industrialized societies. In recent years, treatments for AIS have emerged, including thrombolysis with tissue plasminogen activator (t-PA). Althou...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2010.07.038
更新日期:2010-12-01 00:00:00
abstract::Arthritis is inflammation in a joint often with joint damage, usually accompanied by pain, swelling and stiffness, resulting from infection, trauma, degenerative changes, metabolic disturbances, autoimmune or other causes. It occurs in various forms, including rheumatoid arthritis, osteoarthritis, bacterial arthritis ...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2005.06.021
更新日期:2005-01-01 00:00:00