Abstract：
:Jet lag is a travel-induced circadian rhythm phenomenon that afflicts healthy individuals following long- distance flights through several time zones. The typical jet-lag manifestations - insomnia during local sleep time, day fatigue, reduced concentration, irritability, and exhaustion with mild depression - are attributed to transient desynchronization in the circadian rhythm until the internal biological clock is rephased to the new environmental conditions. There is strong evidence relating affective disorders with circadian rhythm abnormalities. Less convincing suggestions relate jet lag to psychosis. It can be hypothesized that in predisposed individuals jet lag may play a role in triggering exacerbation or even de novo affective disorders. Furthermore, we propose the possibility that psychosis and even schizophrenia can be elicited by jet lag. This outlook gains its support from case studies and some common underlying phase-advanced biological denominators involved in both jet lag sufferers and psychotic patients.
journal_name
Med Hypothesesjournal_title
Medical hypothesesauthors
Katz G,Durst R,Zislin Y,Barel Y,Knobler HYdoi
10.1054/mehy.2000.1094keywords:
subject
Has Abstractpub_date
2001-01-01 00:00:00pages
20-3issue
1eissn
0306-9877issn
1532-2777pii
S0306-9877(00)91094-6journal_volume
56pub_type
杂志文章,评审abstract：:The affected individual of hair loss demands help, because hair is viewed as a sign of youth and good health. Nowadays treatment of alopecia includes drug therapy and hair transplantation. Some drugs may promote hair growth, at least temporarily, but the treatment is effective only in milder alopecia, instead of exten...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2007.09.001
更新日期：2008-01-01 00:00:00
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journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/0306-9877(91)90167-w
更新日期：1991-09-01 00:00:00
abstract：:Almost all solid tumors consist of aneuploid cells with highly abnormal chromosome numbers. Such cancer cells could very well originate from chromosome missegregation which is a disturbingly common phenomenon, happening in 0.01 to 4 percent of cell divisions. Missegregated cells are aneuploid, typically lacking a chro...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2018.08.028
更新日期：2018-11-01 00:00:00
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journal_title：Medical hypotheses
pub_type： 杂志文章
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更新日期：2006-01-01 00:00:00
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journal_title：Medical hypotheses
pub_type： 杂志文章
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更新日期：1980-01-01 00:00:00
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journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2006.10.040
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journal_title：Medical hypotheses
pub_type： 杂志文章
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journal_title：Medical hypotheses
pub_type： 杂志文章
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更新日期：2017-11-01 00:00:00
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journal_title：Medical hypotheses
pub_type： 杂志文章,评审
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更新日期：2010-06-01 00:00:00
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pub_type： 杂志文章
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更新日期：1984-04-01 00:00:00
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journal_title：Medical hypotheses
pub_type： 杂志文章
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更新日期：2008-01-01 00:00:00
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journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1054/mehy.2001.1490
更新日期：2002-06-01 00:00:00
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journal_title：Medical hypotheses
pub_type： 杂志文章
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更新日期：1991-10-01 00:00:00
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journal_title：Medical hypotheses
pub_type： 杂志文章,评审
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更新日期：2015-11-01 00:00:00
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journal_title：Medical hypotheses
pub_type： 杂志文章
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更新日期：2017-07-01 00:00:00
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journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/0306-9877(94)90075-2
更新日期：1994-10-01 00:00:00
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journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2019.109279
更新日期：2019-09-01 00:00:00
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journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2006.04.070
更新日期：2006-01-01 00:00:00
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journal_title：Medical hypotheses
pub_type： 社论
doi：10.1016/j.mehy.2007.07.006
更新日期：2008-01-01 00:00:00
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journal_title：Medical hypotheses
pub_type： 社论
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更新日期：2009-09-01 00:00:00
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pub_type： 杂志文章
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更新日期：2002-10-01 00:00:00
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journal_title：Medical hypotheses
pub_type： 杂志文章
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更新日期：1981-01-01 00:00:00
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更新日期：2019-06-01 00:00:00
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journal_title：Medical hypotheses
pub_type： 杂志文章
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更新日期：2004-01-01 00:00:00
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更新日期：2020-11-01 00:00:00
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journal_title：Medical hypotheses
pub_type： 杂志文章
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更新日期：2010-07-01 00:00:00
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pub_type： 杂志文章
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更新日期：1993-12-01 00:00:00
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journal_title：Medical hypotheses
pub_type： 杂志文章
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更新日期：1998-06-01 00:00:00
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journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/0306-9877(89)90047-9
更新日期：1989-03-01 00:00:00
