An animal analogue of forced unilateral nostril breathing: relevance for physiology and pharmacology.

abstract：:Doppler sonography is used as a routine test for detection of renal artery stenosis (RAS). Although increased peak systolic velocity at the site of the narrowing is a widely accepted method for assessing main renal artery stenosis, tardus parvus phenomenon detected on the downstream blood flow has been used as an alte...

journal_title：Medical hypotheses

authors： Cavalcante Araújo N

更新日期：2019-03-01 00:00:00

abstract：:Multiple sclerosis remains a rare neurological disease of unknown aetiology, with a unique distribution, both geographically and historically. Rare in equatorial regions, it becomes increasingly common in higher latitudes; historically, it was first clinically recognized in the early nineteenth century. A hypothesis, ...

journal_title：Medical hypotheses

authors： Carlyle IP

更新日期：1997-12-01 00:00:00

abstract：:The pancreatic leakage is a lethal postoperative complication to the patients after duodenopancreatectomy for carcinoma of head of pancreas. However, we found that the patients who survived this lethal postoperative complication could potentially acquire a longer survival time comparing with those without postoperativ...

journal_title：Medical hypotheses

authors： Liu H,Liu M,Yuan T,Tang C,Chen P

更新日期：2009-08-01 00:00:00

abstract：:Natural whole foods contain fats as structural components, and have a balance of polyunsaturated fat, monounsaturated fat, and saturated fat. Since we are still a Paleolithic species, adapted to eating only wild foods, it is difficult to justify the consumption of anything other than an overall balance of triglyceride...

journal_title：Medical hypotheses

authors： Broadhurst CL

更新日期：1997-09-01 00:00:00

abstract：:Positive cancer patient outcomes, including increased time to recurrent events, have been associated with increased counts and function of natural killer (NK) cells. NK cell counts and function are elevated following acute exercise, and the generally accepted mechanism of increased recruitment suggests that binding of...

journal_title：Medical hypotheses

authors： Evans W

更新日期：2017-11-01 00:00:00

abstract：:Nearly two million people suffer traumatic brain injury in the US each year. These injuries alter adversely the metabolism of myelin, a major lipid material in brain, both in people and in experimental injuries of animals. A newly discovered and severe human neuropathy from copper deficiency provides evidence that som...

journal_title：Medical hypotheses

authors： Klevay LM

更新日期：2013-12-01 00:00:00

abstract：:A lowered risk of multiple sclerosis (MS) has been reported in the Hutterite community residing mainly in southern Canada. In another anabaptist community, the Old Colony Mennonites (OCM), settled in Canada and spread to Latin America, only a large pedigree with an increased risk of autoimmune diseases, including type...

journal_title：Medical hypotheses

authors： Lauer K

更新日期：2006-01-01 00:00:00

abstract：:Hyperplasia of the coronoid process of the mandible has been observed in conditions like Oral submucous fibrosis, TMJ ankylosis, etc. The etiopathogenesis of this coronoid overgrowth has not been clearly sequenced or adequately hypothesized, and no definite mechanism has so far been advocated to explain this elongatio...

journal_title：Medical hypotheses

authors： Chakranarayan A,Jeyaraj P

更新日期：2011-11-01 00:00:00

abstract：:In plastic and reconstructive surgery, there is a tremendous clinical need for adequate implants are needed to restore soft-tissue defects resulting from tumor resection, traumatic injury, or congenital anomalies. Restoring the aesthetic function of the soft tissue is as important as restoring the natural tissue funct...

journal_title：Medical hypotheses

authors： Chang Q,Lu F

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:The hypotheses of autoimmune, allergic or infectious etiology of severe mental illness have been reported in the scientific literature repeatedly. The main objective of this work is to study the relationship of inflammatory, autoimmunity or recent infection markers with the fact of suffering Severe Mental Di...

journal_title：Medical hypotheses

authors： Olcina Rodríguez JF,Díaz Fernández J,Orta Mira N,López-Briz E,Gómez-Pajares F

更新日期：2019-09-01 00:00:00

abstract：:In addition to classical metastatic pathways, recently gastric cancer was described having an alternative route called "endoluminal exfoliation". Provisional analyses demonstrated, in fact, this kind of shedding is associated with several clinico-pathological features indicative of aggressive behavior and resulted to ...

journal_title：Medical hypotheses

authors： Virgilio E,Balducci G,Mercantini P,Giarnieri E,Giovagnoli MR,Montagnini M,Proietti A,D'Urso R,Cavallini M

更新日期：2018-05-01 00:00:00

abstract：:Based on a consideration of biochemical mechanisms, rational methods for the prevention of cancer and for its positive regression are presented. It is demonstrated that the means employed are fundamentally opposed so that if the preventive method were to be used after the onset of cancer, it would only accelerate its ...

journal_title：Medical hypotheses

authors： Duchesne J

更新日期：1981-04-01 00:00:00

abstract：:Breast cancer associated with pregnancy is defined as the one in which the diagnosis is made in a pregnancy or within one year of delivery. Breast cancer is the second most common malignancy during pregnancy and it is generally considered to have a worse prognosis than the one that is not associated with pregnancy. Th...

journal_title：Medical hypotheses

authors： Michel RM,Aguilar JL,Arrieta O

更新日期：2007-01-01 00:00:00

abstract：:Class II malocclusion is one of the most common orthodontic problems. The main aetiology of Class II malocclusion is mandibular retrognathia. A variety of functional appliances have been used to stimulate mandibular growth in adolescence, however, the effects remain unsatisfactory. Therefore, new approaches are in nee...

journal_title：Medical hypotheses

authors： Li Y,Yang P,Fan X,Wang J,Liu J,Zhao Z,Zhao M

更新日期：2009-03-01 00:00:00

abstract：:An unexpected and novel finding is described and discussed here concerning the synaptic physiology of hippocampal slices during the period of recovery after brain dissection. Contrary to the common notion that the amplitude of synaptic responses recovers in a single exponential rising fashion, we found that synaptic r...

journal_title：Medical hypotheses

authors： Gourov AV

更新日期：2011-12-01 00:00:00

abstract：:In attempts to develop a rational anticancer strategy the same homologous tissue in 3 conditions were used side by side as targets: normal epidermis of the mouse back. Tween 60R-provoked benign epidermal hyperplasia, and carcinogen-provoked malignant condition. In contrast to the highest tolerated doses of the cytosta...

journal_title：Medical hypotheses

authors： Setälä K

更新日期：1982-03-01 00:00:00

abstract：:Pyoderma gangrenosum (PG) is a rare dermatological condition belonging to the group of deep neutrophilic dermatoses. It can display a protracted and refractory course. The list of treatments which have been tried and proved their efficacy is long, but none of them provide constant efficacy. In the absence of gold stan...

journal_title：Medical hypotheses

authors： Kluger N

更新日期：2012-05-01 00:00:00

abstract：:Evidence exists for the presence of a neuro-anatomy that can produce cardiac vasospasm. Recent experimental and clinical data suggest that this neuro-anatomic mechanism can be activated by behavioral events in the psycho-social surround of the patient with coronary artery disease. I hypothesize that this mechanism can...

journal_title：Medical hypotheses

authors： Natelson BH

更新日期：1987-12-01 00:00:00

abstract：:Hypoplastic pineal glands and decreased melatonin levels are found in sudden infant death syndrome. Excess oxygen radical production and inadequate radical quenching is suggested to cause oxidative stress in the brain of sudden infant death syndrome victims. Loss of intraventricular cerebrospinal fluid melatonin could...

journal_title：Medical hypotheses

authors： Maurizi CP

更新日期：1997-11-01 00:00:00

abstract：:At present no good method of assisting the right ventricle of the heart exists. This paper presents a new and effective approach to assisting the right ventricle of the heart which can be utilized independently or during cardiac surgery. Through implementation of this method, and timed inflation and deflation of sever...

journal_title：Medical hypotheses

authors： Gordon RT,Gordon D

更新日期：1979-11-01 00:00:00

abstract：:Developmental alcohol exposure adversely influences the developing brain. Alcohol exposure during rapid brain growth causes cell loss, alters connections between brain regions, and lowers the production of biological substances responsible for the communication among neurons. It is reasonable to suggest that alcohol m...

journal_title：Medical hypotheses

authors： Sher L

更新日期：2004-01-01 00:00:00

abstract：:Initial diagnosis of acute kidney injury (AKI) is usually based on measuring serum-creatinine and blood urea nitrogen levels; however such measurements are still poor in identifying renal injuries at initial stages. These standard matrices are not enough to monitor the outcome and progression of AKI. The prognosis pre...

journal_title：Medical hypotheses

authors： Singh V

更新日期：2016-10-01 00:00:00

abstract：:While cigarette smoking is recognized as an important risk factor in human oral cancers, the effect of water pipe smoking (WPS) on these cancers is not known. WPS is very common in the young adult population, especially in the Middle East, and has been associated with several respiratory problems. However, to date, th...

journal_title：Medical hypotheses

authors： Rastam S,Li FM,Fouad FM,Al Kamal HM,Akil N,Al Moustafa AE

更新日期：2010-03-01 00:00:00

abstract：:"Consciousness" "mood," "identity" and "personality" are all emergent properties from whole-brain organizations; these are typically disturbed in psychiatric disorders. This work proposes that the underlying etiopathology of mental disorders originates from disturbances to global brain dynamics, or "Globalopathies" th...

journal_title：Medical hypotheses

authors： Peled A

更新日期：2013-12-01 00:00:00

abstract：:Posttraumatic stress disorder (PTSD) is a severe anxiety disorder that develops after exposure to trauma. Symptoms include persistent reexperiencing, persistent avoidance, persistent numbing, and persistent hyperarousal. Subsequent to trauma exposure, the onset of symptoms of an acute stress reaction can typically dev...

journal_title：Medical hypotheses

authors： Wallace J

更新日期：2013-06-01 00:00:00

abstract：:COVID-19 due to the SARS-CoV-2 infection is a multi-systemic immune syndrome affecting mainly the lungs, oropharyngeal region, and other vascular endothelial beds. There are tremendous ongoing efforts for the aim of developing drugs against the COVID-19 syndrome-associated inflammation. However, currently no specific ...

journal_title：Medical hypotheses

authors： Beyazit F,Beyazit Y,Tanoglu A,Haznedaroglu IC

更新日期：2020-10-01 00:00:00

abstract：:This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy. ...

journal_title：Medical hypotheses

authors： Dillon SP,Kurien BT,Maier-Moore JS,Wiley GB,Gaffney PM,Scofield RH

更新日期：2012-08-20 00:00:00

abstract：:Articles dealing with the epidemiological aspects of asthma were carefully reviewed in order to support or reject our clinical impression of increased rate of asthma among immigrants. Particular emphasis was put on data on very high or very low rates of asthma. The proposed theories to explain these differences were c...

journal_title：Medical hypotheses

authors： Ballin A,Somekh E,Geva D,Meytes D

更新日期：1998-10-01 00:00:00

abstract：:Parkinson's disease (PD) is the second most common neurodegenerative disease after Alzheimer's disease. The hallmark pathologic feature of PD is dopamine deficiency, caused by the degeneration of nigrostriatal dopaminergic neurons. Current treatments for PD mainly address the dopaminergic features of the disease; howe...

journal_title：Medical hypotheses

authors： Tsai SJ

更新日期：2007-01-01 00:00:00

abstract：:The mechanisms by which blast pressure waves cause mild-to-moderate traumatic brain injury (mTBI) are an open question. Possibilities include acceleration of the head, direct passage of the blast wave via the cranium, and propagation of the blast wave to the brain via a thoracic mechanism. The hypothesis that the blas...

journal_title：Medical hypotheses

authors： Courtney AC,Courtney MW

更新日期：2009-01-01 00:00:00