Abstract：
:This hypothesis named Salerian Addictive Potential (SAP) suggests that the addictive potency of any substance may be calculated with an algebraic equation of A=E/T(max)xt(1/2), where A is the addictive potency, E represents the euphoric potency, T(max) is the time to reach peak plasma concentration, and t(1/2) is the plasma elimination half-life. This review offers medical evidence to suggest there is a negative association between the addictive potency of a substance and T(max) and t(1/2), whereas the euphoric potency of a substance increases its addictive potency. SAP seems incompatible with the current FDA and government sponsored schedule for classification of addictive substances.
journal_name
Med Hypothesesjournal_title
Medical hypothesesauthors
Salerian AJdoi
10.1016/j.mehy.2010.01.008subject
Has Abstractpub_date
2010-06-01 00:00:00pages
1081-3issue
6eissn
0306-9877issn
1532-2777pii
S0306-9877(10)00012-5journal_volume
74pub_type
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