Acupuncture-brain interactions as hypothesized by mood scale recordings.

Abstract:

:Mood expressions encompassing positive scales like "activity, elation, contemplation, calmness" and negative scales like "anger, excitement, depression, fatigue" were applied for introducing a new tool to assess the effects of acupuncture on brain structures. Traditional acupuncture points defined in the literature for their effects on task negative and task positive brain structures were applied to chronic disease patients supposed to have dominant negative mood scales. Burn-out syndrome (n=10) and female chronic pain patients (n=22) showed a significant improvement on positive mood scales and a decline in negative mood scales after 10 acupuncture sessions. We observed a direct effect of acupuncture on brain structures in 5 burn-out syndrome patients showing an immediate, fast suppression of unusual slow high amplitude EEG waves in response to acupuncture needle rotation. These EEG waves described here for the first time in awake patients disappeared after 10 sessions but gradually returned after 1-1.5 years without acupuncture. This was accompanied with deterioration of positive mood scales and a return to negative mood scales. Both male (n=16) and female chronic pain patients reported a significant decrease of pain intensity after 10 sessions. Female patients only, however, showed a linear correlation between initial pain intensity and pain relief as well as a linear correlation between changes in pain intensity and mood scales accompanied by a drop of their heart rate during the acupuncture sessions. We hypothesized that mood scale recordings are a sensitive and specific new tool to reveal individual acupuncture-brain interaction.

journal_name

Med Hypotheses

journal_title

Medical hypotheses

authors

Acker H,Schmidt-Rathjens C,Acker T,Fandrey J,Ehleben W

doi

10.1016/j.mehy.2015.05.013

subject

Has Abstract

pub_date

2015-09-01 00:00:00

pages

371-9

issue

3

eissn

0306-9877

issn

1532-2777

pii

S0306-9877(15)00201-7

journal_volume

85

pub_type

杂志文章
  • On consciousness: what is the role of emergence?

    abstract::Can consciousness be understood as the ongoing active creation of information (of meaning)? 'Emergence', the central concept in this hypothesis, plays an essentially different role in it than in theories previously proposed. ...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/0306-9877(92)90023-6

    authors: Atkin A

    更新日期:1992-08-01 00:00:00

  • Hypothesis: Phytate is an important unrecognised nutrient and potential intravenous drug for preventing vascular calcification.

    abstract::Cardiovascular calcification (CVC) associated with conditions such as ageing, diabetes or renal impairment, results from the deposition of hydroxyapatite in the endothelium or media of blood vessels. Key medical management options are directed towards controlling plasma calcium and phosphate concentrations (e.g. parat...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/j.mehy.2016.07.005

    authors: Joubert P,Ketteler M,Salcedo C,Perello J

    更新日期:2016-09-01 00:00:00

  • Does yawning increase arousal through mechanical stimulation of the carotid body?

    abstract::Yawning is a stereotyped event that occurs in humans and animals from fish to mammals, but neither its mechanisms nor its functions are entirely known. Its widespread nature suggests that it has important physiological functions. It is associated with stretching of muscles in a large area, but the function of this str...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/j.mehy.2007.06.027

    authors: Matikainen J,Elo H

    更新日期:2008-01-01 00:00:00

  • Would creatine supplementation augment exercise performance during a low carbohydrate high fat diet?

    abstract::Low carbohydrate high fat (LCHF) diets are emerging in popularity. Several athletics have adopted LCHF diets in an attempt to improve exercise performance and body composition by enhancing fat utilization. However, these diets impair maximal and supramaximal exercise performance due to limited glycogen stores as well ...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/j.mehy.2020.110369

    authors: Kaviani M,Izadi A,Heshmati J

    更新日期:2021-01-01 00:00:00

  • Edaravone: a new therapeutic approach for the treatment of acute stroke.

    abstract::Acute stroke, including acute ischemic stroke (AIS) and acute hemorrhagic stroke, (AHS) is a common medical problem with particular relevance to the demographic changes in industrialized societies. In recent years, treatments for AIS have emerged, including thrombolysis with tissue plasminogen activator (t-PA). Althou...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/j.mehy.2010.07.038

    authors: Kikuchi K,Kawahara K,Miyagi N,Uchikado H,Kuramoto T,Morimoto Y,Tancharoen S,Miura N,Takenouchi K,Oyama Y,Shrestha B,Matsuda F,Yoshida Y,Arimura S,Mera K,Tada K,Yoshinaga N,Maenosono R,Ohno Y,Hashiguchi T,Maruyama

    更新日期:2010-12-01 00:00:00

  • Predicting chronic symptoms after an acute "stressor"--lessons learned from 3 medical conditions.

    abstract::Stressful events occur in the lives of millions of individuals each year. Such events, or "stressors", are experiences that threaten personal well-being, and include traumatic events such as motor vehicle collision, infectious illness, and situations such as military deployment. While most individuals recover from suc...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/j.mehy.2004.03.022

    authors: McLean SA,Clauw DJ

    更新日期:2004-01-01 00:00:00

  • Views on the sustenance of resistant Mycobacterium tuberculosis in the environment.

    abstract::Microbial resistance to conventional as well as newly introduced drugs is a hallmark feature of several infectious diseases, notably tuberculosis. It is hypothesized that the greater the selective pressure exerted by increasingly potent drugs, the more rapidly is an organism able to adapt to a drug-containing environm...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/0306-9877(95)90215-5

    authors: Basu A,Mistry NF,Antia NH

    更新日期:1995-11-01 00:00:00

  • The glass ceiling: A biological phenomenon.

    abstract::Many brilliant and ambitious young women lose their drive for top careers after childbirth. New maternal impulses are at odds with their original ambitions and for many mothers stress and frustration will be the result as they have to combine child care with workweeks of 60-80h to reach or remain at the top. Pregnancy...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/j.mehy.2017.07.002

    authors: Schulpen TWJ

    更新日期:2017-09-01 00:00:00

  • Is there a relationship between tissue inhibitor of metalloproteinase-1 and transforming growth factor-beta 1 with respect to malignant melanoma progression?

    abstract::Recent articles about the roles and relationships of tissue inhibitor of metalloproteinase-1 and transforming growth factor-beta 1 in various types of normal tissues and malignancies give rise to the question: 'Is there a relationship between them with regard to malignant melanoma progression?' In the light of many re...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1054/mehy.2001.1270

    authors: Kurdoglu M,Güllü IH,Akalin I

    更新日期:2001-08-01 00:00:00

  • Genotrim, a DNA-customized nutrigenomic product, targets genetic factors of obesity: hypothesizing a dopamine-glucose correlation demonstrating reward deficiency syndrome (RDS).

    abstract::Obesity is the second largest cause of preventable death in the United States. Historically, obesity was considered a behavioral problem that could be simply addressed with behavioral modifications in diet and exercise. As scientific advancements have demonstrated in other neurological healthcare conditions such as al...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/j.mehy.2006.08.041

    authors: Blum K,Chen TJ,Meshkin B,Downs BW,Gordon CA,Blum S,Mangucci JF,Braverman ER,Arcuri V,Deutsch R,Pons MM

    更新日期:2007-01-01 00:00:00

  • Anorexia nervosa--a noradrenergic dysregulation hypothesis.

    abstract::Anorexia nervosa manifests a wide range of features which cannot fully be explained on the basis of socio-cultural pressures to be thin, nor by starvation, nor dehydration. Evidence is emerging of a significant neurobiological contribution to its aetiology. However there has to date been no explanation for its pathoge...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/j.mehy.2012.01.033

    authors: Nunn K,Frampton I,Lask B

    更新日期:2012-05-01 00:00:00

  • Vascular heparan sulfates may limit the ability of leukocytes to penetrate the endothelial barrier--implications for use of glucosamine in inflammatory disorders.

    abstract::Oral glucosamine has anti-inflammatory activity in rodents, and anecdotal evidence suggests that it may be clinically useful in inflammatory bowel disorders. A possible explanation is that supplemental glucosamine increases production of heparan sulfate (HS) proteoglycans by the vascular endothelium, thereby improving...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/s0306-9877(98)90247-x

    authors: McCarty MF

    更新日期:1998-07-01 00:00:00

  • Aluminum binds to the hyperphosphorylated tau in Alzheimer's disease: a hypothesis.

    abstract::The hypterphosphorylation of tau proteins is a well-established step in the expression of the pathological features in Alzheimer's disease (AD). While a primary event that links aluminum and AD, the so-called 'aluminum hypotheses', is far from being demonstrated, however, the metal ion could be an important etiologica...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/0306-9877(95)90131-0

    authors: Zatta PF

    更新日期:1995-03-01 00:00:00

  • Applying principles of physics to the airway to help explain the relationship between asthma and gastroesophageal reflux.

    abstract::Gastroesophageal reflux (GER) and asthma have been linked, but the true nature of this relationship is incompletely understood. Most of the literature examining this association has implicated GER as the factor contributing to asthma. GER has also been linked to conditions of the upper airway like sinusitis and obstru...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/j.mehy.2009.12.030

    authors: Turbyville JC

    更新日期:2010-06-01 00:00:00

  • Hypothesis: is the skin and tissue loss associated with septic purpura fulminans temperature related? Parallels with the anatomical distribution of frostbite.

    abstract::Purpura fulminans is a life threatening complication of many septic states, most notably meningococcaemia. It can also occur due to congenital deficiency of anticoagulant proteins. The pathophysiology of purpura fulminans is complex and not fully understood, but involves abnormalities of coagulation pathways, damage t...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/j.mehy.2007.11.011

    authors: Oram J,Bodenham A

    更新日期:2008-01-01 00:00:00

  • Lymphatic flow modulation as adjunct therapy for septic shock.

    abstract::The lymphatic system is an important component of human health and is critical in maintaining microcirculatory flow and immune system homeostasis. During septic shock, increased capillary permeability results in excess filtration of intravascular fluid and solutes producing interstitial edema with subsequent hydrostat...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/j.mehy.2020.109748

    authors: Pruitt LG

    更新日期:2020-09-01 00:00:00

  • Gender differences in stem cell population are induced by pregnancy.

    abstract::Gender differences in stem cell population have recently been identified. Blood and tissue samples from women showed consistent elevation of hematopoietic stem cell populations, mesenchymal stem cell populations and endothelial progenitor cells compared to men of similar ages. We and others have shown an increase in h...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/j.mehy.2012.06.029

    authors: El-Badri NS,Groer M

    更新日期:2012-10-01 00:00:00

  • On the general theory of neural circuitry.

    abstract::A general theory of neural circuitry is proposed wherein neural impulses travel in a continuous circuit from the brain to the extremities and back to the brain. At the extremities the impulse may be modified by the environment there. At the spinal column the return signal is compared with the outgoing signal and the a...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/0306-9877(94)90002-7

    authors: Kingham DJ

    更新日期:1994-05-01 00:00:00

  • The progression of the tubulointerstitial fibrosis driven by stress-induced "proliferation-death" vicious circle.

    abstract::Several hypotheses have been developed to interpret the progression of tubulointerstitial fibrosis (TF), including senescence, epithelial-mesenchymal transition, inflammation, chronic hypoxia, and reactive oxygen species. All of these hypotheses are based on persistent cell injury and localized cell death. Proliferati...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/j.mehy.2014.01.014

    authors: Chen BC,Bai YH,Tang LL,Wang BQ,Liu B,Cai Y,Peng X,Yang YR,Zheng SL

    更新日期:2014-06-01 00:00:00

  • Consideration of vaccination against the FSGS factor.

    abstract::Focal segmental glomerulosclerosis (FSGS) is a common cause of nephrotic disease in adults, and it is thought to be increasing in incidence. FSGS is often difficult to treat and even has a high propensity to relapse after transplant. Indeed, this suggests that there might be some circulating factor responsible for pro...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1054/mehy.2001.1438

    authors: Altschuler EL

    更新日期:2001-12-01 00:00:00

  • First and second things, and the operations of conscience in science.

    abstract::Why is modern science less efficient than it used to be, why has revolutionary science declined, and why has science become so dishonest? One plausible explanation behind these observations comes from an essay First and second things published by CS Lewis. First Things are the goals that are given priority as the prim...

    journal_title:Medical hypotheses

    pub_type: 社论

    doi:10.1016/j.mehy.2009.08.017

    authors: Charlton BG

    更新日期:2010-01-01 00:00:00

  • Is a drill-less dental filling possible?

    abstract::Dental caries, a bacterial process that results in the acidic destruction of tooth structure, has historically been managed by the mechanical excavation of diseased tooth structure and then restoration with a synthetic material. The mechanical excavation of the infected site is most commonly achieved by a dental handp...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/j.mehy.2011.05.002

    authors: Quock RL,Patel SA,Falcao FA,Barros JA

    更新日期:2011-09-01 00:00:00

  • Calcium sulfide (CaS), a donor of hydrogen sulfide (H(2)S): a new antihypertensive drug?

    abstract::Hypertension is the leading cause of cardiovascular diseases, and an estimated 972 million people in the world are suffering from this problem. Indubitably, hypertension is an important worldwide public-health challenge. In recent years many efforts have been made to devise novel therapies involving new targets implic...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/j.mehy.2009.03.030

    authors: Li YF,Xiao CS,Hui RT

    更新日期:2009-09-01 00:00:00

  • Maize meal predisposes to endemic squamous cancer of the oesophagus in Africa: breakdown of esterified linoleic acid to the free form in stored meal leads to increased intragastric PGE2 production and a low-acid reflux.

    abstract::Endemic cancer of the oesophagus in Africa is associated with the use of maize as the staple. In one African community endemic cancer of the oesophagus has been shown to have a strong statistical association with the consumption of foods based on maize in the meal form. A strong association with consumption of maize m...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/j.mehy.2006.05.037

    authors: Sammon AM,Iputo JE

    更新日期:2006-01-01 00:00:00

  • Tumor necrosis factor-alpha: a continuum of liability between insulin-dependent diabetes mellitus, non-insulin-dependent diabetes mellitus and carcinoma (review).

    abstract::In this review, tumor necrosis factor-alpha (TNF-alpha) is identified as the uniting principle linking the pathogenesis of insulin-dependent diabetes mellitus (IDDM), non-insulin dependent diabetes mellitus (NIDDM) and carcinoma. Elevated TNF-alpha initially increases, and then inhibits, the activity of a number of ke...

    journal_title:Medical hypotheses

    pub_type: 杂志文章,评审

    doi:10.1054/mehy.1997.0008

    authors: Holden RJ,Pakula IS,Mooney PA

    更新日期:1999-04-01 00:00:00

  • Is ATP-sensitive K+ channel (K+ATP) recruitment a common mechanism for ECG-ST segment depression and elevation?

    abstract::ATP sensitive (K(+)(ATP)) potassium cardiac channels are recruited when ATP levels are low as in ischemic injury and acute trauma. Such activation results in ECG-ST elevation and cardiac arrhythmias. K(+)(ATP) channel recruitment may be blocked by the sulfonylurea glibenclamide, permitting a wide variety of animal exp...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/s0306-9877(03)00055-0

    authors: Hoffman I,Saltzman B

    更新日期:2003-04-01 00:00:00

  • Chronic infection and the origin of adaptive immune system.

    abstract::It has been speculated that the rise of the adaptive immune system in jawed vertebrates some 400 million years ago gave them a superior protection to detect and defend against pathogens that became more elusive and/or virulent to the host that had only innate immune system. First, this line of thought implies that ada...

    journal_title:Medical hypotheses

    pub_type: 杂志文章,评审

    doi:10.1016/j.mehy.2010.02.031

    authors: Usharauli D

    更新日期:2010-08-01 00:00:00

  • Possible connection between milk and coronary heart disease: the calcium hypothesis.

    abstract::Excessive milk consumption may adversely affect the circulation on account of the high calcium content of milk and because lactose promotes the intestinal absorption of calcium. Excessive calcium intake may cause calcification and rigidification of the large elastic arteries, which could be an important factor in caus...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1054/mehy.1999.0992

    authors: Seely S

    更新日期:2000-05-01 00:00:00

  • A possible role of decreased oxidative resistance of low-density lipoproteins in the early formation of carotid atherosclerosis.

    abstract::Ischaemic stroke ranks among the most important causes of death and disability in developed countries. Abnormal lipid metabolism is among the several factors that have a role in the pathogenesis of atherosclerosis. We hypothesize that the decreased resistance of low-density lipoproteins against oxidative stress is an ...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1054/mehy.2000.1252

    authors: Bereczki D,Balla G,Csiba L,Jeney V,Valikovics A,Magyar T,Balla J

    更新日期:2001-06-01 00:00:00

  • Electroacupuncture at acupoints could predict the outcome of anterior nucleus thalamus high-frequency electrical stimulation in medically refractory epilepsy.

    abstract::Preliminary reports have demonstrated that anterior nucleus thalamus high-frequency electrical stimulation (ANT-HFS) is an effective treatment for patients who suffer from medically refractory epilepsy. However, its extensive application has been hampered by the high cost and the unpredictable outcome before the opera...

    journal_title:Medical hypotheses

    pub_type: 杂志文章

    doi:10.1016/j.mehy.2013.06.001

    authors: Yan N,Chen N,Lu J,Wang Y,Wang W

    更新日期:2013-09-01 00:00:00