Abstract：
:Preliminary reports have demonstrated that anterior nucleus thalamus high-frequency electrical stimulation (ANT-HFS) is an effective treatment for patients who suffer from medically refractory epilepsy. However, its extensive application has been hampered by the high cost and the unpredictable outcome before the operation. Just like ANT-HFS in the brain, electroacupuncture (EA) at acupoints with electrical stimulation is also efficient in treating medically refractory epilepsy. Although the therapeutic mechanisms involve different activated positions, the neurotransmitters generated by the electrical stimulation are similar. It has been demonstrated that both ANT-HFS and EA at acupoints are related to an imbalance between the excitatory [glutamate (Glu), aspartate (Asp)] and inhibitory [GABA, glycine (Gly) and taurine (Tau)] neuronal transmitters. We, therefore, hypothesize that outcome of EA at acupoints can predict the therapeutic effect of ANT-HFS.
journal_name
Med Hypothesesjournal_title
Medical hypothesesauthors
Yan N,Chen N,Lu J,Wang Y,Wang Wdoi
10.1016/j.mehy.2013.06.001subject
Has Abstractpub_date
2013-09-01 00:00:00pages
426-8issue
3eissn
0306-9877issn
1532-2777pii
S0306-9877(13)00278-8journal_volume
81pub_type
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