Abstract:
:In humans, the nasal retina projects to the contralateral hemisphere, whereas the temporal retina projects ipsilaterally. The nasotemporal line that divides the retina into crossed and uncrossed parts coincides with the vertical meridian through the fovea. This normal projection of the retina is severely altered in albinism, in which the nasotemporal line shifted into the temporal retina with temporal retinal fibers cross the midline at the optic chiasm. This study proposes the loss of binocular vision as direct cause for misrouting of temporal retinal fibers and shifting of the nasotemporal line temporally in albinism. It is supported by many observations that clearly indicate that loss of binocular vision causes uncrossed retinal fibers to cross the midline. This hypothesis may alert scientists and clinicians to find ways to prevent or minimize the loss of binocular vision that may occur in some diseases such as albinism and early squint. Hopefully, this will minimize the misrouting of temporal fibers and improve vision in such diseases.
journal_name
Med Hypothesesjournal_title
Medical hypothesesauthors
Banihani SMdoi
10.1016/j.mehy.2015.06.028subject
Has Abstractpub_date
2015-10-01 00:00:00pages
458-62issue
4eissn
0306-9877issn
1532-2777pii
S0306-9877(15)00247-9journal_volume
85pub_type
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