Abstract：
:Although the role of the lymphatic circulation in the uptake of dietary fat is well established, the absorption of water-soluble compounds, secreted by the enterocyte into the lymph, has received little attention. In the present study an estimate is made of the amount of dietary glucose that can be absorbed via the lymphatic system in the rat.
journal_name
Med Hypothesesjournal_title
Medical hypothesesauthors
Argilés JM,Fernández-López JA,Casado J,Alemany Mdoi
10.1016/0306-9877(90)90169-fsubject
Has Abstractpub_date
1990-11-01 00:00:00pages
169-71issue
3eissn
0306-9877issn
1532-2777pii
0306-9877(90)90169-Fjournal_volume
33pub_type
杂志文章abstract：:Cholesterol efflux from macrophage foam cells, the initial step of reverse cholesterol transport, is assumed to be the most relevant step with respect to atherosclerosis. As one of the ATP-binding cassette transporter (ABC) family members, ABCG1 plays a critical role in the process of cholesterol efflux. It has been r...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2006.06.042
更新日期：2007-01-01 00:00:00
abstract：:Hyperemesis gravidarum (HG) is the most severe form of illness within the spectrum of nausea and vomiting of pregnancy. Liver disease, usually consisting of mild serum transaminase elevation, occurs in almost 50% of patients with HG. While multiple risk factors have been proposed, the etiology and underlying mechanism...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2005.05.035
更新日期：2005-01-01 00:00:00
abstract：:A holistic-organismic approach is suggested as foundation for intensified, systematic inquiry into relationships among adult attachment styles and various dimensions of physical and mental health. Exploratory findings of differences in stamina associated with adult attachment style are noted. The extent to which attac...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/s0306-9877(03)00125-7
更新日期：2003-07-01 00:00:00
abstract：:It has been previously proposed that conscious process involves the collapse of quantum, dynamical brain states through conscious observation. It has been further proposed that the brain process has an active role in selecting the status of uncertain stimuli. On the basis of these proposals it was predicted that event...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2003.10.002
更新日期：2004-01-01 00:00:00
abstract：:The various neurotransmitter systems postulated to be involved in the pathogenesis of Gilles de la Tourette syndrome(GTS) are described with special reference to the endogenous opioid system(EOS). Malfunction of the opioid system is proposed as the underlying disturbance in this disease causing secondary dysfunction o...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/0306-9877(86)90112-x
更新日期：1986-04-01 00:00:00
abstract：BACKGROUND:The hypotheses of autoimmune, allergic or infectious etiology of severe mental illness have been reported in the scientific literature repeatedly. The main objective of this work is to study the relationship of inflammatory, autoimmunity or recent infection markers with the fact of suffering Severe Mental Di...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2019.109279
更新日期：2019-09-01 00:00:00
abstract：:Alzheimer's disease (AD) may be related to nutritional deficiencies from exocrine pancreatic insufficiency (EPI) with mal-absorption of essential nutrients, vitamins and minerals. EPI occurs in about twenty percent of the elderly population, sometimes without obvious symptoms, a number similar to the incidence of AD. ...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2017.03.020
更新日期：2017-05-01 00:00:00
abstract：:Rheumatic heart disease (RHD) remains a major cause of cardiac related mortality and morbidity in the developing countries due to poor diagnosis and lack of proper therapeutics. The definite reason of heart valve injury during RHD is poorly understood. Valvular endothelial cells play an important role in pathogenesis ...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2016.09.001
更新日期：2016-10-01 00:00:00
abstract：:SARS-CoV-2 virus has resulted in a devastating pandemic of COVID-19. Exploring compounds that could offer a breakthrough in treatment is the need of the hour. Re-positioning cheap, freely available and safe drugs is a priority. The paper proposes evidence for the potential use of diethylcarbamazine (DEC) in the treatm...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2020.109843
更新日期：2020-10-01 00:00:00
abstract：:Preliminary but increasing evidence suggests that attention-deficit/hyperactivity disorder (ADHD), Tourette's syndrome (TS), and restless legs syndrome (RLS) may be comorbid. In the present article, we hypothesize that ADHD, TS, and RLS may be part of a spectrum, and that iron deficiency contributes to the pathophysio...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2007.10.013
更新日期：2008-01-01 00:00:00
abstract：:Osteosarcoma is the most common primary malignant tumor of bone. Except for the improvement in five-year survival achieved by the adoption of neoadjuvant chemotherapy strategy, there are nearly no improvement for the treatment of osteosarcoma in the past 30 years, especially for the patients with metastatic disease. I...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2012.01.038
更新日期：2012-05-01 00:00:00
abstract：:Almost all solid tumors consist of aneuploid cells with highly abnormal chromosome numbers. Such cancer cells could very well originate from chromosome missegregation which is a disturbingly common phenomenon, happening in 0.01 to 4 percent of cell divisions. Missegregated cells are aneuploid, typically lacking a chro...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2018.08.028
更新日期：2018-11-01 00:00:00
abstract：:Endometriosis is a common gynecological disorder that affects approximately 6-10% of the female population impairing the quality of life of patients. Several pathophysiologic pathways have been proposed as potential regulators of its severity; however, to date, the processes that trigger the onset and that influence t...
journal_title：Medical hypotheses
pub_type： 杂志文章,评审
doi：10.1016/j.mehy.2019.109414
更新日期：2019-12-01 00:00:00
abstract：:Bacterial biofilms have been found in many human bacterial infectious processes including chronic rhinosinusitis. It was found also at the surface of nasal polyps, and both at the surface of the nasal part and the stalk of the antrochoanal polyp. However, our recent research clearly demonstrated the presence of the bi...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2010.04.005
更新日期：2010-10-01 00:00:00
abstract：:Growing evidences suggest a link between normal tension glaucoma (NTG) and Alzheimer's disease (AD). Both of them are progressive neurodegenerative disorders. Recently researches provide a clue that optineurin may be a new common underlying risk factor involved in NTG and AD. OPTINEURIN (OPTN) gene coding for "optineu...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2011.06.040
更新日期：2011-10-01 00:00:00
abstract：:Most cancer cells would not result in devastating tumours if it were not for their ability to metastasize. The process of cancer metastasis involves significant cell shape, motility, and adhesive changes of pre-cancerous cells, and the remodelling of the extracellular matrix, as well as cognate properties of neighbour...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2007.04.042
更新日期：2008-01-01 00:00:00
abstract：:The paradigm of an immune system presumes that a system arose specifically to combat infection -- hence its name. This paradigm gained credibility with the discovery of antibodies and anamnestic immunity, even though these are relatively late arrivals in evolution. Another presumption has been that thymus-dependent T ...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1054/mehy.1997.0645
更新日期：1999-03-01 00:00:00
abstract：:Since forced unilateral nostril breathing activates the contralateral brain hemisphere, an animal analogue of this technique could be provided by methylmethacrylate gluing large plastic pellets in either the right or left nostrils in a group of rats. A large number of physiological, pharmacological, and immunological ...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/0306-9877(89)90047-9
更新日期：1989-03-01 00:00:00
abstract：:N-acetylaspartate (NAA) is an intermediary metabolite that is found in relatively high concentrations in the human brain. More specifically, NAA is so concentrated in the neurons that it generates one of the most visible peaks in nuclear magnetic resonance (NMR) spectra, thus allowing NAA to serve as "a neuronal marke...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2006.02.047
更新日期：2006-01-01 00:00:00
abstract：:The incidence of insulin-dependent diabetes mellitus (IDDM), a chronic disease with a well-known genetic basis, is highest in Scandinavian and Sardinian populations. The high incidence of IDDM in Scandinavia and Sardinia, which were genetically isolated from the spread of agriculturists in Europe about 8000 years ago,...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1054/mehy.1997.0663
更新日期：1999-05-01 00:00:00
abstract：:Celiac disease is an immune mediated disorder, the only one with a well-established origin, resulting from a permanent gluten intolerance. Although a gluten-free diet is currently the "safe" and appropriate therapy for celiac disease, this is not always an easy and simple option as "harmful" gluten may contaminate foo...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2007.04.003
更新日期：2007-01-01 00:00:00
abstract：:NETosis, being an alternative form of cell death is the creation of web-like chromatin decondensates by suitably primed neutrophils as a response to stimulus aimed at containing and eliminating the same. In certain situations, it causes more harm than benefit in the form of bystander damage directly or via activation ...
journal_title：Medical hypotheses
pub_type： 信件
doi：10.1016/j.mehy.2020.109968
更新日期：2020-11-01 00:00:00
abstract：:Puberty is starting earlier than ever before and there are serious physiological and sociological implications as a result of this development. Current research has focused on the potential role of high caloric, and commensurate high adiposity, contributions to early puberty. However, girls with normal BMI also appear...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2015.06.029
更新日期：2015-10-01 00:00:00
abstract：:Hepatic encephalopathy (HE) is a common neuropsychiatric complication of liver disease affecting about 20-30% patients with cirrhosis. HE may only affect quality of life (e.g. impairments in attention; coordination; driving ability), but in some patients this progresses to coma and death; defining mortality in those w...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2006.12.061
更新日期：2007-01-01 00:00:00
abstract：:Oxidative stress-mediated neurodegeneration is responsible for 12% mortality around the globe. Alzheimer's Disease (AD) and Parkinson's Disease (PD) are the most prevalent neurodegenerative diseases, associated with modulation of acetylcholine levels and amyloid beta accumulation & dopamine level and alpha-synuclein o...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2020.109872
更新日期：2020-10-01 00:00:00
abstract：:Oral water irrigation devices (WIDs) are widely used for oral physiotherapy in homes and dental clinics throughout the world. A major area of concern in the use of WIDs has been the possibility of injury to the sulcular epithelium and underlying tissue. There are several documented clinical cases of tissue injury with...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/0306-9877(85)90110-0
更新日期：1985-12-01 00:00:00
abstract：:Several attempts to control the dreadfulness of SARS-CoV-2 are still underway. Based on the literature evidences we have speculated a prospective contemporary remedy, which was categorized into Specificity, Remedy, and a Conveyor. In which, pros and cons were discussed and inferred the possible alternatives. (a) Speci...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2020.109976
更新日期：2020-11-01 00:00:00
abstract：:Treatment-resistant schizophrenia (TRS) is one of the subgroups of schizophrenia of which little is known with regard to its optimal mechanism. Treatment response, either as full remission of symptoms or prediction by biomarker, is important in psychiatry. We have proposed a model that integrates dopaminergic and glut...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/j.mehy.2020.110159
更新日期：2020-10-01 00:00:00
abstract：:A study of the strikingly low incidence of sudden infant death syndrome in Eastern countries revealed significant differences in infant handling thought to have an etiological bearing; therefore this writer suggested that adoption of certain Eastern methods of nursing may reduce the incidence of sudden infant death sy...
journal_title：Medical hypotheses
pub_type： 杂志文章
doi：10.1016/s0306-9877(97)90254-1
更新日期：1997-07-01 00:00:00
abstract：:In 1937, Drs. Moritz and Oldt described arteriolar injuries in the kidneys (and other viscera) in hypertension, across the age range, in both sexes, and, in different races. This hypothesis proposes that injuries to vasomotor nerves cause the arteriolar injury in the kidney in hypertension, (as well as that in the ute...
journal_title：Medical hypotheses
pub_type： 历史文章,杂志文章
doi：10.1016/j.mehy.2017.12.025
更新日期：2018-02-01 00:00:00
