Abstract:
:The collagenous structure of the knee menisci is integral to the mechanical integrity of the tissue and the knee joint. The tie-fibre structure of the tissue has largely been neglected, despite previous studies demonstrating its correlation with radial stiffness. This study has evaluated the structure of the tie-fibres of bovine menisci using 2D and 3D microscopy techniques. Standard collagen and proteoglycan (PG) staining and 2D light microscopy techniques were conducted. For the first time, the collagenous structure of the menisci was evaluated using 3D, second harmonic generation (SHG) microscopy. This technique facilitated the imaging of collagen structure in thick sections (50-100 μm). Imaging identified that tie-fibres of the menisci arborize from the outer margin of the meniscus toward the inner tip. This arborization is associated with the structural arrangement of the circumferential fibres. SHG microscopy has definitively demonstrated the 3D organization of tie-fibres in both sheets and bundles. The hierarchy of the structure is related to the organization of circumferential fascicles. Large tie-fibre sheets bifurcate into smaller sheets to surround circumferential fascicles of decreasing size. The tie-fibres emanate from the lamellar layer that appears to surround the entire meniscus. At the tibial and femoral surfaces these tie-fibre sheets branch perpendicularly into the meniscal body. The relationship between tie-fibres and blood vessels in the menisci was also observed in this study. Tie-fibre sheets surround the blood vessels and an associated PG-rich region. This subunit of the menisci has not previously been described. The size of tie-fibre sheets surrounding the vessels appeared to be associated with the size of blood vessel. These structural findings have implications in understanding the mechanics of the menisci. Further, refinement of the complex structure of the tie-fibres is important in understanding the consequences of injury and disease in the menisci. The framework of meniscus architecture also defines benchmarks for the development of tissue-engineered replacements in the future.
journal_name
J Anatjournal_title
Journal of anatomyauthors
Andrews SH,Rattner JB,Abusara Z,Adesida A,Shrive NG,Ronsky JLdoi
10.1111/joa.12170subject
Has Abstractpub_date
2014-05-01 00:00:00pages
531-7issue
5eissn
0021-8782issn
1469-7580journal_volume
224pub_type
杂志文章abstract::The morphological features of odontoblast processes in young kitten odontoblasts were studied by thin section and freeze-fracture electron microscopy. Freeze-fracture replication revealed depressions with particles on the plasma membranes of the proximal parts of odontoblast processes. Comparison with thin sections su...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1984-05-01 00:00:00
abstract::The sheep is a commonly used animal model for human lumbar spine surgery, but only in vitro investigations comparing the human and ovine spine exist. Spinal musculature has previously not been compared between man and sheep. This additional knowledge could further indicate to what extent these species are biomechanica...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12354
更新日期:2015-10-01 00:00:00
abstract::Interhemsipheric interaction between the human cerebral hemispheres is served by abundant white-matter fibres in the human corpus callosum (CC). Damage to these fibres has notable behavioural and cognitive sequelae that depend on the exact location of the fibre loss. Until now, correlations between fibre loss and neur...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2006.00615.x
更新日期:2006-09-01 00:00:00
abstract::The present paper reports the results of the first investigation of the semicircular canals in a living, small animal by means of high spatial resolution magnetic resonance imaging. This procedure is noninvasive and allows identification of the endolymphatic and perilymphatic spaces yielding a morphology quite consist...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1992-04-01 00:00:00
abstract::Knowledge of the pattern of human craniofacial development in the fetal period is important for understanding the mechanisms underlying the emergence of variations in human craniofacial morphology. However, the precise character of the prenatal ontogenetic development of the human cranium has yet to be fully establish...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2008.00884.x
更新日期:2008-05-01 00:00:00
abstract::Pancreatic duct glands (PDGs) are tubule-alveolar glands associated with the pancreatic duct system and can be considered the anatomical counterpart of peribiliary glands (PBGs) found within the biliary tree. Recently, we demonstrated that endodermal precursor niches exist fetally and postnatally and are composed func...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12418
更新日期:2016-03-01 00:00:00
abstract::The rete testis in the domestic fowl (Gallus gallus domesticus), Japanese quail (Coturnix coturnix japonica), guinea-fowl (Numida meleagris galeata) and drake (Anas platyrhynchos) was studied histologically and with both the scanning and transmission electron microscopes. All the birds have rete epithelial cells varyi...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1982-08-01 00:00:00
abstract::Adult male Sprague-Dawley rats were randomly assigned to two groups: control and anaemic. Anaemia was induced by periodical blood withdrawal. Extensor digitorum longus and soleus muscles were excised under pentobarbital sodium total anaesthesia and processed for transmission electron microscopy, histochemical and bioc...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2008.00908.x
更新日期:2008-06-01 00:00:00
abstract::Glutamate kills neurons by excitotoxicity, which is caused by sustained activation of glutamate receptors. In recent years, it has been shown that glutamate can also be toxic to white matter oligodendrocytes and to myelin by this mechanism. In particular, glutamate receptor-mediated injury to these cells can be trigge...
journal_title:Journal of anatomy
pub_type: 杂志文章,评审
doi:10.1111/j.1469-7580.2007.00733.x
更新日期:2007-06-01 00:00:00
abstract::The differentiation of the bulbar region and arterial outflow tract of the developing mouse heart was investigated by analysing serial transverse sections through the heart region of mouse embryos isolated between the eleventh and fifteenth day of gestation. Over this period of time, we observed the configurational an...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1988-06-01 00:00:00
abstract::The ultrastructure of the developing fetal lamb myocardium was studied in a series of animals spanning 29 days of gestation to term, and compared with newborn and adult animals. All major ultrastructural features which characterise the adult myocyte were found in early fetal life, although with considerably different ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1983-12-01 00:00:00
abstract::Femoral neck fractures are a major cause of morbidity and mortality in elderly humans. In addition to the age-related loss of cancellous bone, changes to the microstructure and morphology of the metaphyseal cortex may be a contributing factor in osteoporotic hip fractures. Recent investigations have identified a hyper...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.2001.19820153.x
更新日期:2001-02-01 00:00:00
abstract::It is well known that large pyroninophilic cell proliferation in regional lymphoid tissue preceds and accompanies cell-mediated immunological reactions. In the present study of lymph node responses in the pregnant rat it was found that there were no significant differences between large pyronionphilic cell counts from...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1975-07-01 00:00:00
abstract::This study describes the degenerative changes of the axon terminals making synaptic contacts with the neurons in the submucous ganglia of guinea pig small and large intestines following left or right cervical vagotomy. There were no noticeable ultrastructural changes 1 d after the operation. Beginning at the 3rd posto...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1995-12-01 00:00:00
abstract::Enthesophytes are bony projections that arise from the sites of ligament, tendon or joint capsule attachment to a bone. They are seen rarely in radiographic findings in young adults, as these bony adaptations are assumed to develop slowly over time. However, in recent years, the presence of an enlarged external occipi...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12466
更新日期:2016-08-01 00:00:00
abstract::In experimental studies addressing the regulation of myelin formation and maintenance by Schwann cells, the sympathetic nervous system of young adult rodents has served a key role as an essentially nonmyelinated yet modifiable control tissue. Nevertheless there is clear evidence of substantial myelination in the super...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1994-04-01 00:00:00
abstract::The collagen in the endoneurium is present as argyrophilic reticular fibres, which show up as thin, weakly birefringent greenish fibres when studied by aid of the Picrosirius-polarization method, and are composed of loosely arranged thin collagen fibrils. The epineurium consists of thick non-argyrophilic collagen fibr...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1983-08-01 00:00:00
abstract::Networks linking single genes to multiple phenotypic outcomes can be founded on local anatomical interactions as well as on systemic factors like biochemical products. Here we explore the effects of such interactions by investigating the competing spatial demands of brain and masticatory muscle growth within the hyper...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.13393
更新日期:2021-01-13 00:00:00
abstract::Standard immunohistochemical methods were used to detect the presence of vimentin, cytokeratin 8, cytokeratin 18, macrophages and Langerhans cells in the human tonsillar epithelium in formalin-fixed and frozen tissue specimens. Vimentin detection was restricted to infiltrating cells of the lymphoid series, dendritic a...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.2001.19960663.x
更新日期:2001-12-01 00:00:00
abstract::Electron microscopy has been used to investigate whether the transversely striated columns of the connecting piece in the neck region of guinea pig spermatozoa, undergo lengthening and shortening as a result of the forces generated during motility. Motile spermatozoa were subjected to near-instantaneous rapid freezing...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2008.00919.x
更新日期:2008-09-01 00:00:00
abstract::Three modes of construction of the rectus sheath above the arcuate line were found in a study of 40 cadavers. The classical description occurred most frequently, in 24 cases. The other constructions conformed to those described in earlier studies although the incidences were different. The accessory internal oblique m...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1986-04-01 00:00:00
abstract::Mastoid canals (tunnels) were observed in 41 (7.7%) of 265 dry human skulls. The canals were 2-27 mm long. This feature has not been reported before. dissection of 30 mastoid regions in cadavers showed that the canals contained a branch of the occipital artery and a vein. It is possible that during development of the ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1996-02-01 00:00:00
abstract::A study has been made of the distribution of granulated metrial gland cells in the non-pregnant uterus, in the pre-implantation uterus and in the post-implantation interconceptual uterus of pregnant albino mice. Granulated cells were only rarely seen in the non-pregnant uterus. In the pre-implantation uterus, they wer...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1981-12-01 00:00:00
abstract::A one day symposium of the Anatomical Society of Great Britain and Ireland was held at the Royal Free Hospital in London on the 17th September 1999, on the topic of 'Mechanisms of ageing and longevity'. The following are abstracts of communications and posters presented at the meeting. ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.2000.19620293.x
更新日期:2000-02-01 00:00:00
abstract::Advances in X-ray computed tomography (CT) have led to a rise in the use of non-destructive imaging methods in comparative anatomy. Among these is contrast-enhanced CT scanning, which employs chemical stains to visualize soft tissues. Specimens may then be 'digitally dissected', producing detailed, three-dimensional d...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.13007
更新日期:2019-08-01 00:00:00
abstract::A quantitative comparison of the internal diameters of cerebral feeder arteries (internal carotid and vertebral) and the aorta in developing non-human eutherians, metatherians and monotremes has been made, with the aim of determining if there are differences in cerebral arterial flow between the three infraclasses of ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12422
更新日期:2016-03-01 00:00:00
abstract::The present study has shown that the secondary curvature in the cervical spine of the human fetus develops at a much earlier age than has been thought. It may, in fact, develop soon after the embryo first acquires a neck and begins to uncurl. The early appearance of this curvature may be related to the early developme...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1977-07-01 00:00:00
abstract::Pulmonary alveolar septa are thought to contain at least two types of fibroblasts that are termed myofibroblasts and lipofibroblasts based on their morphological characteristics. Lipofibroblasts possess cytoplasmic lipid inclusions (lipid bodies or droplets) and are involved in several important functions, such as sur...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12677
更新日期:2017-12-01 00:00:00
abstract::The T-tubule system in cardiac muscle cells has been investigated with the electron microscope in 10 adult rats after infiltration with horseradish peroxidase. All cardiac muscle cells possess a T-system, but its complexity varies according to the region of the heart. It is most extensive in the general ventricular my...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1978-09-01 00:00:00
abstract::Collagen fibrils from different rat tendons have been investigated by freeze-fracture and transmission electron microscopy. In all cases, marked differences in both fibril morphology and subfibrillar organisation have been consistently found between the tendon core (composed of large and heterogeneous fibrils comprisi...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1990-10-01 00:00:00