Abstract：
:Femoral neck fractures are a major cause of morbidity and mortality in elderly humans. In addition to the age-related loss of cancellous bone, changes to the microstructure and morphology of the metaphyseal cortex may be a contributing factor in osteoporotic hip fractures. Recent investigations have identified a hypermineralised tissue on the neck of the femur and trochanteric region that increases in fractional area with advancing age in both males (Boyce & Bloebaum, 1993) and females (Vajda & Bloebaum, 1999). The aim of this study was to determine if the hypermineralised tissue previously observed on the proximal femur is calcified fibrocartilage. Regional variations in the fractional area of hypermineralised tissue, cortical bone, and porosity of the cortical bone along the neck of the femur and lesser trochanter were also quantified. Comparison of back scattered electron and light microscope images of the same area show that regions of hypermineralised tissue correlate with the regions of calcified fibrocartilage from tendon and capsular insertions. The hypermineralised tissue and calcified fibrocartilage had similar morphological features such as the interdigitations of the calcified fibrocartilage into the bone, lacunar spaces, and distinctly shaped pores adjacent to the 2 tissues. Regions of the neck that did not contain insertions were covered with periosteum. There were no regional differences (P > 0.05) on the superior and inferior femoral neck in terms of the percentage area of hypermineralised calcified fibrocartilage, cortical bone, or cortical bone porosity. The lesser trochanter exhibited regional differences in the fractional area of hypermineralised calcified fibrocartilage (P = 0.007) and cortical bone (P = 0.007) but not porosity of the cortical bone (P > 0.05). The effects of calcified fibrocartilage on femoral neck periosteal expansion, repair, and mechanics are unknown, but may play a role in osteoporotic fractures and intracapsular fracture healing.
journal_name
J Anatjournal_title
Journal of anatomyauthors
Shea JE,Vajda EG,Bloebaum RDdoi
10.1046/j.1469-7580.2001.19820153.xkeywords:
subject
Has Abstractpub_date
2001-02-01 00:00:00pages
153-62issue
Pt 2eissn
0021-8782issn
1469-7580journal_volume
198pub_type
杂志文章abstract：:Adult male Sprague-Dawley rats were randomly assigned to two groups: control and anaemic. Anaemia was induced by periodical blood withdrawal. Extensor digitorum longus and soleus muscles were excised under pentobarbital sodium total anaesthesia and processed for transmission electron microscopy, histochemical and bioc...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2008.00908.x
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journal_title：Journal of anatomy
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doi：10.1046/j.1469-7580.2001.19840481.x
更新日期：2001-04-01 00:00:00
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journal_title：Journal of anatomy
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doi：
更新日期：1983-09-01 00:00:00
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journal_title：Journal of anatomy
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doi：
更新日期：1983-03-01 00:00:00
abstract：:The behavioral differences in muscle use are related to the fiber type composition of the muscles among other variables. The aim of this study was to examine the degree of heterogeneity in the fiber type composition in the rat temporalis muscle. The temporalis muscle was taken from 10-week-old Wistar strain male rats ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2008.00990.x
更新日期：2008-12-01 00:00:00
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journal_title：Journal of anatomy
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abstract：:The knee joint consists of multiple interacting tissues that are prone to injury- and disease-related degeneration. Although much is known about the structure and function of the knee's constituent tissues, relatively little is known about their cellular origin and the mechanisms governing their segregation. To invest...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2008.00966.x
更新日期：2008-11-01 00:00:00
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journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1989-04-01 00:00:00
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journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1996-04-01 00:00:00
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journal_title：Journal of anatomy
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doi：
更新日期：1995-04-01 00:00:00
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journal_title：Journal of anatomy
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doi：10.1111/j.1469-7580.2007.00733.x
更新日期：2007-06-01 00:00:00
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journal_title：Journal of anatomy
pub_type： 杂志文章
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journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1988-06-01 00:00:00
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journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12283
更新日期：2015-12-01 00:00:00
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journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1977-12-01 00:00:00
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journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1981-03-01 00:00:00
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journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1991-12-01 00:00:00
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journal_title：Journal of anatomy
pub_type： 杂志文章,评审
doi：10.1046/j.1469-7580.2000.19740571.x
更新日期：2000-11-01 00:00:00
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journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1990-04-01 00:00:00
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journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.13302
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journal_title：Journal of anatomy
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doi：
更新日期：1995-06-01 00:00:00
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journal_title：Journal of anatomy
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doi：
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journal_title：Journal of anatomy
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doi：
更新日期：1978-03-01 00:00:00
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journal_title：Journal of anatomy
pub_type： 杂志文章
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journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1988-08-01 00:00:00
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journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1986-02-01 00:00:00
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journal_title：Journal of anatomy
pub_type： 杂志文章
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更新日期：2011-08-01 00:00:00
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journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12745
更新日期：2018-02-01 00:00:00
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journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1984-09-01 00:00:00
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journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1982-03-01 00:00:00
