Abstract:
:The differentiation of the bulbar region and arterial outflow tract of the developing mouse heart was investigated by analysing serial transverse sections through the heart region of mouse embryos isolated between the eleventh and fifteenth day of gestation. Over this period of time, we observed the configurational and cellular changes occurring within the wall of this region of the heart, being particularly interested in the histological appearance of the cellular constituents of the spiral ridges and their eventual apposition and fusion to form the spiral septum. We observed that the mesenchyme cells of which the ridges are largely composed are initially orientated in the direction of the outflow tract, but subsequently realign themselves when the individual ridges become oblique and spiral in their configuration. The tissue that gives rise to the spiral septum, namely the 'bulbar cushions' proximally, and the 'truncal cushions' in the rest of the outflow tract appear at all stages to be continuous structures. We saw no evidence that they initially develop as separate entities, and subsequently fuse. Furthermore, no evidence of cell death was observed in either the mesenchyme tissue or in the wall of the outflow tract. We have therefore suggested that, contrary to the findings of Pexieder (1978), pre-programmed cell death probably plays no significant part in the development of the spiral septum in the mouse, though we cannot exclude the possibility that there may be species differences between the events associated with spiral septum formation in avian and mammalian embryos. We conclude from our histological observations that the changes that occur in the arterial outflow tract in the mouse are probably brought about by the haemodynamic effect of the forces of blood flow impinging on its walls and that this initiates a series of events that are controlled to a considerable degree by pre-programmed genetic instruction.
journal_name
J Anatjournal_title
Journal of anatomyauthors
Fananapazir K,Kaufman MHsubject
Has Abstractpub_date
1988-06-01 00:00:00pages
157-72eissn
0021-8782issn
1469-7580journal_volume
158pub_type
杂志文章abstract::The microvascular anatomy of discrete knee ligaments in adult rabbits is described. Epiligamentous plexuses give rise to a limited number of vessels which penetrate deeply into ligament substance. Intraligamentous vessels are usually longitudinally orientated, widely separated linear anastomoses but occasionally compl...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1990-10-01 00:00:00
abstract::The volume and shape (the axial ratio:length/diameter) of mitochondria in periportal and perihepatic hepatocytes from newborn, 5 days old, 10 days old and adult male ddY mice were analysed by quantitative electron microscopy. In newborn animals, the volume and relative histogram of the axial ratio were not significant...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1984-09-01 00:00:00
abstract::A silver impregnation technique (Linder, 1978) has been applied to whole mounts of the rat iris. The results suggest that only sensory fibres, both myelinated and non-myelinated, are stained. They disappear only after a trigeminal lesion and their distribution is different from that of catecholaminergic intrinsic fibr...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1984-03-01 00:00:00
abstract::The ACTH cells form a layer 1-8 cells thick, dorsal to the prolactin cells in the rostral pars distalis. They react only mildly with a variety of stains including PAS-lead haematoxylin. Their nuclear diameters vary seasonally in a manner that closely parallels that of the prolactin cells. The relative volumes of the A...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1982-08-01 00:00:00
abstract::Morphometric analysis of the kidney of the camel was carried out on gross slices and histological sections using standard morphometric methods. The renal cortex occupied about 50% by volume of the kidney, and the ratio of the thickness of the medulla to that of the cortex was about 4:1. The relative thickness of the m...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1979-08-01 00:00:00
abstract::The structure of the cardiac foramen ovale from 17 species representing six cetacean families, the Monodontidae, Phocoenidae, Delphinidae, Ziphiidae, Balaenidae and the Balaenopteridae, was studied using the scanning electron microscope. Eight white whale fetuses (Delphinapterus leucas) and a narwhal fetus (Monodon mo...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2007.00743.x
更新日期:2007-07-01 00:00:00
abstract::The retinal vasculature of postmortem normal human and diabetic eyes was studied using an immunohistochemical technique in conjunction with confocal laser scanning microscopy. The technique, which stained for von Willebrand factor, allowed both large areas of the retinal vasculature to be visualised and abnormalities ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.1999.19410089.x
更新日期:1999-01-01 00:00:00
abstract::The gross and microscopic anatomy of the Cape fur seal heart, lung, liver, spleen, stomach, intestine and kidneys (n = 31 seals) is described. Absolute and relative size of organs from 30 male seals are presented, with histological examination conducted on 7 animals. The relationship between log body weight, log organ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.1999.19520235.x
更新日期:1999-08-01 00:00:00
abstract::This investigation is based upon the pineal organs of 92 specimens of 36 species of the family Pteropodidae (Mammalia, Chiroptera). The size of the megachiropteran pineal correlates well with body size (r = 0.864), confirming the former conclusions that generally larger bodied bats have larger pineals. The range of th...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1990-02-01 00:00:00
abstract::The normal number and arrangement of motoneurons contributing fibres, via the median and radial nerves, to the forearm muscles of the rat were determined at different stages of postnatal development. Horseradish peroxidase was applied directly to the proximal cut ends of the nerves in 5, 10, 21 days old and adult rats...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1990-08-01 00:00:00
abstract::The developing cortical surfaces of long bones are sculpted and modeled by periosteal osteoclasts and osteoblasts. These surfaces also receive the insertions of tendons and ligaments, and these insertion sites too are modeled to form the root systems that anchor them into the cortical bone. The regulatory molecules th...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12145
更新日期:2014-04-01 00:00:00
abstract::On the basis of its internal structure, the ball of the foot can be divided into three transverse areas, each with a different mechanical function: (1) an area proximal to the heads of the metatarsals in which the retinacula cutis are developed into a series of transverse bands, and in which the deep fibres of the pla...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1976-07-01 00:00:00
abstract::The collagen in the endoneurium is present as argyrophilic reticular fibres, which show up as thin, weakly birefringent greenish fibres when studied by aid of the Picrosirius-polarization method, and are composed of loosely arranged thin collagen fibrils. The epineurium consists of thick non-argyrophilic collagen fibr...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1983-08-01 00:00:00
abstract::The aortic plexus is a network of sympathetic nerves positioned along the infrarenal abdominal aorta. Recently, we characterized the aortic plexus and its ganglia (inferior mesenteric, left/right spermatic, and prehypogastric ganglion) in males; however, the literature minimally describes its anatomy in females. In th...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12436
更新日期:2016-05-01 00:00:00
abstract::Experimental evidence indicates that lymph nodes in humans undergo alterations during ageing. This is clinically important because of the crucial role of these organs in the immune system and their lymph reabsorption and drainage function. Although some age-related changes in lymph node histoarchitecture have been des...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2010.01213.x
更新日期:2010-05-01 00:00:00
abstract::The vomeronasal system (VNS) has been extensively studied within specific animal families, such as Rodentia. However, the study of the VNS in other families, such as Canidae, has long been neglected. Among canids, the vomeronasal organ (VNO) has only been studied in detail in the dog, and no studies have examined the ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.13254
更新日期:2020-11-01 00:00:00
abstract::Axonal elements of the carotid baroreceptor zone of nine domestic fowls were examined with the electron microscope after either distal vagal ganglionectomy or midcervical vagotomy. The bare baroreceptor endings and the central axon of the encapsulated baroreceptor endings degenerated within 5 to 15 days after ganglion...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1984-10-01 00:00:00
abstract::Tarentola annularis is a climbing gecko with a wide distribution in Africa north of the equator. In the present paper, we describe the development of the osteocranium of this lizard, from the first appearance of the cranial elements up to the point of hatching. This is based on a combination of histology and cleared a...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.13213
更新日期:2020-09-01 00:00:00
abstract::The ultrastructure of 3 fibrocartilages is described at the insertion of the adult rat Achilles tendon. Enthesial fibrocartilage lies at the tendon-bone junction, sesamoid fibrocartilage in the deep surface of the tendon where it presses on the calcaneus, and periosteal fibrocartilage covers the opposing surface of th...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1996-08-01 00:00:00
abstract::The distributing of vimentin and cytokeratin intermediate filaments within the cells of the dental follicle and developing periodontal ligament is described during eruption of the rat 1st molar tooth. Alcohol-fixed tissues from animals ranging from neonates to 12 wk old were cryosectioned, immunolabelled with monoclon...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1996-06-01 00:00:00
abstract::It is unknown whether loading of the lower limbs through additional storage of fat mass as evident in obesity would promote muscular adaptations similar to those seen with resistance exercise. It is also unclear whether ageing modulates any such adjustments. This study aimed to examine the relationships between adipos...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12248
更新日期:2014-12-01 00:00:00
abstract::The morphological transition from the simple epidermis that contacts the amniotic fluid of embryonic crocodilians to the adult epidermis required in a terrestrial environment has never been described. We used light and electron microscopy to study the development, differentiation and keratinisation of the epidermis of...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.2001.19830265.x
更新日期:2001-03-01 00:00:00
abstract::Data are presented on the postnatal growth of the mouse bladder. Both bladder size (measured as surface area) and bladder wet weight increase steadily with age, respectively reaching 2.5 times and 4 times their newborn values by the age of ten weeks. Despite this growth, which may be due principally to non-urothelial ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1985-12-01 00:00:00
abstract::Bone growth at the cranial sutures relies on proliferation of osteogenic progenitor cells and/or differentiation of osteoblasts. The current study was undertaken to assess these events in relation to suture growth and fusion. A total of 21 pigs, divided into three age groups (0.5-1.5 months, 3-4 months and 5-7 months)...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2007.00761.x
更新日期:2007-09-01 00:00:00
abstract::Epiphyses of man and dog in various stages of union are described. As union approaches, new cartilage is added to the epiphyseal surface of the cartilaginous epiphyseal plate by chondrification of the epiphyseal marrow. Before and during early union the cellular arrangement of the cartilaginous epiphyseal plate is wel...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1975-09-01 00:00:00
abstract::Proper assessment of outcome in clinical trials of neural transplantation requires both biochemical and imaging indices of graft survival, and behavioural and physiological indices of graft function. For transplantation in Huntington's disease, a variety of ligands that are selective for striatal degeneration and graf...
journal_title:Journal of anatomy
pub_type: 杂志文章,评审
doi:10.1046/j.1469-7580.2000.19640597.x
更新日期:2000-05-01 00:00:00
abstract::Four forelimbs of 3 platypuses and 3 forelimbs of 2 echidnas were examined to study the precise form of the brachial plexus and to clarify the structural characteristics of the brachial plexus in phylogeny. The spinal components contributing to the plexus (C4-T2) and the formation patterns of the 3 trunks of the plexu...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.1997.19030447.x
更新日期:1997-04-01 00:00:00
abstract::A symposium on extramedullary haematopoiesis was held on 11-12 September 1996 at the University of St Andrews. The following are abstracts of papers and posters presented at the meeting. ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.1997.19020311.x
更新日期:1997-02-01 00:00:00
abstract::Examination of spinal cords of 5 days old mice showed a number of examples of oligodendrocytes, in various phases of mitosis, which remained in contact with the axons which they were myelinating. Cells in prophases had thick processes between the perikaryon and the myelinating axons but as mitosis proceeded the oligod...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1980-10-01 00:00:00
abstract::The endoskeleton of elasmobranchs (sharks and rays) is comprised largely of unmineralized cartilage, differing fundamentally from the bony skeletons of other vertebrates. Elasmobranch skeletons are further distinguished by a tessellated surface mineralization, a layer of minute, polygonal, mineralized tiles called tes...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12508
更新日期:2016-11-01 00:00:00