Abstract:
:In experimental studies addressing the regulation of myelin formation and maintenance by Schwann cells, the sympathetic nervous system of young adult rodents has served a key role as an essentially nonmyelinated yet modifiable control tissue. Nevertheless there is clear evidence of substantial myelination in the superior cervical ganglion (SCG) of normal mice and rats of more advanced age. Against this background, interpretation of experimental outcomes in particular sympathetic tissues will require detailed quantitative control data taking account of animal age. To provide a baseline for future investigations on myelin remodelling, an ultrastructural morphometric study of myelinated fibres in the SCG was undertaken in 4 strains (QS, Balb/C, C57 and CBA) of adult male mice aged 32-72 wk. Numbers of myelinated fibres in SCG cross-sections varied substantially between individual animals, and the mean numbers for QS (132), Balb/C (165) and CBA (254) were significantly higher than that for C57 (32). Both axonal and fibre diameter were distributed unimodally (means for the 4 strains ranged from 2.3-2.4 microns and 3.2-3.6 microns respectively). Myelin spiral length was distributed unimodally and skewed to the right (range of means = 227-357 microns) and was significantly greater in QS mice as compared with the other 3 strains. While the mean g ratio (axonal diameter/fibre diameter) was significantly lower in QS mice than in the other 3 strains, the range for mean g ratio was 0.64-0.73, indicating that myelination had proceeded appropriately even though late in onset in this tissue. The index of circularity was high in all strains, both for axons (range of means = 0.80-0.88) and fibres (range of means = 0.84-0.89). The small axonal and fibre diameter and unimodal distribution are consistent with the characteristics of autonomic myelinated fibres and it is probable that most are postganglionic sympathetic fibres arising within the SCG. In terms of providing a sufficient population of myelinated fibres for future experimental studies, the QS, Balb/C and CBA strains would be preferable to C57 mice.
journal_name
J Anatjournal_title
Journal of anatomyauthors
Little GJ,Heath JWsubject
Has Abstractpub_date
1994-04-01 00:00:00pages
387-98eissn
0021-8782issn
1469-7580journal_volume
184 ( Pt 2)pub_type
杂志文章abstract::The neurotropic effect of the distal stump of transected sciatic nerve on regenerating axons emerging from the proximal stump was investigated in rats by the coculture of excised neonatal dorsal root ganglia and segments of degenerated and nondegenerated sciatic nerves. In all cultures, neurites from the ganglion exte...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1995-02-01 00:00:00
abstract::The arrangement and proportion of collagen fibres and fibre bundles in the dermis of the pig have been investigated with light microscopical (Nomarski's interference contrast, polarization optics) and scanning electron microscopical methods. Skin samples were obtained from different body regions of wild boars, domesti...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1982-01-01 00:00:00
abstract::Both scanning (SEM) and transmission (TEM) electron microscopic studies of the major ductules and ducts of the perfused epididymal region of the drake were reported. The SEM correlated with TEM studies and confirmed some previous observations that the non-ciliated Types I and II cells in the proximal and distal effere...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1982-10-01 00:00:00
abstract::Complex I is one of the respiratory chain enzymes related to NADH dehydrogenase and is an encoded gene product derived from both nuclear and mitochondrial genomes. Transcription levels of ND1 (mitochondrial) and 51 kDa (nuclear) subunits of complex I in the postnatal development of the intrinsic muscle in rat tongues ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.2003.00152.x
更新日期:2003-02-01 00:00:00
abstract::A study has been made of the distribution of granulated metrial gland cells in the non-pregnant uterus, in the pre-implantation uterus and in the post-implantation interconceptual uterus of pregnant albino mice. Granulated cells were only rarely seen in the non-pregnant uterus. In the pre-implantation uterus, they wer...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1981-12-01 00:00:00
abstract::Surgical interruption of the gastrointestinal tract is widely used for investigating the structure of the enteric nervous system and in the treatment of certain pathological conditions of the gastrointestinal tract. The effects of transection and end-to-end anastomosis and myotomy on nerve cells of the myenteric plexu...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1996-04-01 00:00:00
abstract::It is unknown whether loading of the lower limbs through additional storage of fat mass as evident in obesity would promote muscular adaptations similar to those seen with resistance exercise. It is also unclear whether ageing modulates any such adjustments. This study aimed to examine the relationships between adipos...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12248
更新日期:2014-12-01 00:00:00
abstract::In this study we investigated immunohistochemically the distribution of VIP in ampullary and isthmic segments of the rabbit oviduct at different hormonal stages in order to correlate the presence of VIP with the morphological and functional differences between the two oviduct segments. Noticeable changes in the VIP-po...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1990-08-01 00:00:00
abstract::The distribution of enteroendocrine cells showing immunoreactivities to four peptides and one amine was examined in the gastric mucosa of the opossum during postnatal development using specific immunocytochemical methods. Gastrin-, BPP-, glucagon-, somatostatin- and 5-HT-immunoreactive cells were identified in the gas...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1986-10-01 00:00:00
abstract::Continuous tooth replacement is common for tetrapods, but some groups of acrodont lepidosaurs have lost the ability to replace their dentition (monophyodonty). Acrodonty, where the tooth attaches to the apex of the jawbone, is an unusual form of tooth attachment that has been associated with the highly autapomorphic c...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12754
更新日期:2018-03-01 00:00:00
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journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2006.00552.x
更新日期:2006-06-01 00:00:00
abstract::The moment arm of a muscle represents its leverage or torque-producing capacity, and is indicative of the role of the muscle in joint actuation. The objective of this study was to undertake a systematic review of the moment arms of the major muscles spanning the glenohumeral joint during abduction, flexion and axial r...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12903
更新日期:2019-01-01 00:00:00
abstract::Fertilised chicken eggs were incubated for 48 hours while exposed to pulsed trains of magnetic fields having a duration of 0-5 ms, a rise time of 42 microsecond, and a pulse repetition rate of 100 at a magnetic field flux density of 1 microT. Some eggs were exposed to 1,552 rad X-rays as a positive control. After expo...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1988-04-01 00:00:00
abstract::The surface coating of the pneumonocytes in the lungs of five human neonates was studied by conventional electron microscopy and by cytochemical techniques. These techniques included staining with colloidal iron oxide, cationic ferritin, Ruthenium red, Ruthenium hexamine trichloride, high iron diamine and the periodic...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1984-09-01 00:00:00
abstract::Congenitally corrected transposition of the great arteries (ccTGA) is a rare congenital malformation which associates discordant atrioventricular and ventriculo-arterial connections. Although frequently associated with a ventricular septal defect (VSD), its anatomy remains controversial. This could be due in hearts wi...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.13097
更新日期:2020-02-01 00:00:00
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journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1977-09-01 00:00:00
abstract::Contracture of collagen fibres in the gubernaculum has been suggested as a mechanism responsible for fetal descent of the testis. We measured the collagen content of the gubernaculum, fetal thigh muscle and umbilical cord tissue by assaying its hydroxyproline and protein content in 194 male pig fetuses between 60 and ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1989-12-01 00:00:00
abstract::Muscle moment arms were measured for major muscles of the pelvic limb of the ostrich (Struthio camelus) in order to assess specific functional behaviour and to apply this to locomotor performance. Pelvic limbs of six juvenile ostriches were used for this study. The tendon travel technique was used to measure moment ar...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2007.00762.x
更新日期:2007-09-01 00:00:00
abstract::A series of semen samples from recently fertile men was obtained by masturbation. They were washed and placed in short term culture in BWW medium, and labelled either with tritiated uridine or tritiated tyrosine. Control samples were labelled in the presence of actinomycin D and puromycin respectively, and examined by...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1996-02-01 00:00:00
abstract::The labyrinth has two functional parts: the cochlea for audition and the vestibular system for equilibrioception. In the latter, the semicircular ducts and the otolithic organs are sensitive to rotational and linear accelerations of the head, respectively. The labyrinthine morphology influences perception accuracy, he...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12619
更新日期:2017-07-01 00:00:00
abstract::The ligamentous attachments of the lumbar spinous processes were studied by dissection and histological examination in seven dogs, three cats and six baboons. Unlike man, the lumbar spines of these animals do not possess a supraspinous ligament and there is no decussation of the erector spinae tendons in the lower lum...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1980-03-01 00:00:00
abstract::The importance of controlling litter size in growth studies is verified for Rattus norvegicus. A method of studying growth of the cranial base bones in the median sagittal plane is described and figures for growth rate in micrometres per day have been produced for the age range 4-480 days. The age range 4 to 80 days i...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1983-03-01 00:00:00
abstract::The dogma that cutaneous wound healing is impaired as a function of age is largely unsubstantiated. This can be attributed to poor experimental design of human studies, the lack of subject characterisation with the exclusion of disease processes, and the study of inappropriate animal models. Structural and functional ...
journal_title:Journal of anatomy
pub_type: 杂志文章,评审
doi:
更新日期:1995-08-01 00:00:00
abstract::It is well established that many tissue-derived factors are involved in blood vessel formation, but evidence is now emerging that endothelial cells themselves represent a crucial source of instructive signals to non-vascular tissue cells during organ development. Thus, endothelial cell signalling is currently believed...
journal_title:Journal of anatomy
pub_type: 杂志文章,评审
doi:10.1111/j.1469-7580.2007.00790.x
更新日期:2007-10-01 00:00:00
abstract::The hooked element in the pes of turtles was historically identified by most palaeontologists and embryologists as a modified fifth metatarsal, and often used as evidence to unite turtles with other reptiles with a hooked element. Some recent embryological studies, however, revealed that this element might represent a...
journal_title:Journal of anatomy
pub_type: 杂志文章,评审
doi:10.1111/joa.12103
更新日期:2013-11-01 00:00:00
abstract::Although systematic reviews are conducted in the field of anatomical research, no instruments exist for the assessment of study quality. Thus, our objective was to develop a valid tool that reliably assesses the methodological quality of observational cadaveric studies. The QUACS scale (QUality Appraisal for Cadaveric...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12292
更新日期:2015-05-01 00:00:00
abstract::The present paper describes a novel structure, termed the peri-albumen layer, in the egg-envelopes of the quail Coturnix japonica. It reacts with Alcian blue and exists between the egg white and the shell membrane. Ultrastructurally, it is of fine granular structure and forms a fenestrate sheet, the width of which is ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.2003.00197.x
更新日期:2003-07-01 00:00:00
abstract::Experimental evidence indicates that lymph nodes in humans undergo alterations during ageing. This is clinically important because of the crucial role of these organs in the immune system and their lymph reabsorption and drainage function. Although some age-related changes in lymph node histoarchitecture have been des...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2010.01213.x
更新日期:2010-05-01 00:00:00
abstract::A histological study has shown that considerable amounts of lipid accumulate in the oxyntico-peptic cells of the proventriculus of domestic fowls deprived of food. Lipid droplets were first seen in the cells 6 hours after commencing the fast and they reached a maximum in 24 hours; a decrease was detected histologicall...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1975-12-01 00:00:00
abstract::Blood flow to the pancreatic islets of the anaesthetised rat was measured using the microsphere method. Basal flow was 29 (+/- 6) microliter/min per pancreas which was equivalent to 2.1 (+/- 0.2)% of the total pancreatic flow. The intravenous administration of 4 IU of soluble insulin, which rendered the animals hypogl...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1989-04-01 00:00:00