Abstract:
:Bird song has historically been considered an almost exclusively male trait, an observation fundamental to the formulation of Darwin's theory of sexual selection. Like other male ornaments, song is used by male songbirds to attract females and compete with rivals. Thus, bird song has become a textbook example of the power of sexual selection to lead to extreme neurological and behavioural sex differences. Here we present an extensive survey and ancestral state reconstruction of female song across songbirds showing that female song is present in 71% of surveyed species including 32 families, and that females sang in the common ancestor of modern songbirds. Our results reverse classical assumptions about the evolution of song and sex differences in birds. The challenge now is to identify whether sexual selection alone or broader processes, such as social or natural selection, best explain the evolution of elaborate traits in both sexes.
journal_name
Nat Communjournal_title
Nature communicationsauthors
Odom KJ,Hall ML,Riebel K,Omland KE,Langmore NEdoi
10.1038/ncomms4379subject
Has Abstractpub_date
2014-03-04 00:00:00pages
3379issn
2041-1723pii
ncomms4379journal_volume
5pub_type
杂志文章abstract::The high Aβ42/Aβ40 production ratio is a hallmark of familial Alzheimer's disease, which can be caused by mutations in the amyloid precursor protein (APP). The C-terminus of Aβ is generated by γ-secretase cleavage within the transmembrane domain of APP (APPTM), a process that is primed by an initial ε-cleavage at eith...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms4037
更新日期:2014-01-01 00:00:00
abstract::In the central nervous system, most synapses show a fast mode of neurotransmitter release known as synchronous release followed by a phase of asynchronous release, which extends over tens of milliseconds to seconds. Synapsin II (SYN2) is a member of the multigene synapsin family (SYN1/2/3) of synaptic vesicle phosphop...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms2515
更新日期:2013-01-01 00:00:00
abstract::The study of multicellular development is grounded in two complementary domains: cell biomechanics, which examines how physical forces shape the embryo, and genetic regulation and molecular signalling, which concern how cells determine their states and behaviours. Integrating both sides into a unified framework is cru...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms13929
更新日期:2017-01-23 00:00:00
abstract::One key route for controlling reaction selectivity in heterogeneous catalysis is to prepare catalysts that exhibit only specific types of sites required for desired product formation. Here we show that alkanethiolate self-assembled monolayers with varying surface densities can be used to tune selectivity to desired hy...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms3448
更新日期:2013-01-01 00:00:00
abstract::We introduce a microfluidic platform that enables off-chip single-cell RNA-seq after multi-generational lineage tracking under controlled culture conditions. We use this platform to generate whole-transcriptome profiles of primary, activated murine CD8+ T-cell and lymphocytic leukemia cell line lineages. Here we repor...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms10220
更新日期:2016-01-06 00:00:00
abstract::Modern science has developed well-defined and versatile sets of chemicals to perform many specific tasks, yet the diversity of these reagents is so large that it can be impractical for any one lab to stock everything they might need. At the same time, isssues of stability or limited supply mean these chemicals can be ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-13328-6
更新日期:2019-12-02 00:00:00
abstract::While intron retention (IR) is considered a widely conserved and distinct mechanism of gene expression control, its regulation is poorly understood. Here we show that DNA methylation directly regulates IR. We also find reduced occupancy of MeCP2 near the splice junctions of retained introns, mirroring the reduced DNA ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms15134
更新日期:2017-05-08 00:00:00
abstract::The midge, Belgica antarctica, is the only insect endemic to Antarctica, and thus it offers a powerful model for probing responses to extreme temperatures, freeze tolerance, dehydration, osmotic stress, ultraviolet radiation and other forms of environmental stress. Here we present the first genome assembly of an extre...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms5611
更新日期:2014-08-12 00:00:00
abstract::CDKL5 deficiency disorder (CDD) is characterized by epilepsy, intellectual disability, and autistic features, and CDKL5-deficient mice exhibit a constellation of behavioral phenotypes reminiscent of the human disorder. We previously found that CDKL5 dysfunction in forebrain glutamatergic neurons results in deficits in...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-10689-w
更新日期:2019-06-14 00:00:00
abstract::Highly specific Cas9 nucleases derived from SpCas9 are valuable tools for genome editing, but their wide applications are hampered by a lack of knowledge governing guide RNA (gRNA) activity. Here, we perform a genome-scale screen to measure gRNA activity for two highly specific SpCas9 variants (eSpCas9(1.1) and SpCas9...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-12281-8
更新日期:2019-09-19 00:00:00
abstract::In conventional computers, wiring between transistors is required to enable the execution of Boolean logic functions. This has resulted in processors in which billions of transistors are physically interconnected, which limits integration densities, gives rise to huge power consumption and restricts processing speeds....
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms1201
更新日期:2011-02-15 00:00:00
abstract::Noble metal nanoparticles stabilized by organic ligands are important for applications in assembly, site-specific bioconjugate labelling and sensing, drug delivery and medical therapy, molecular recognition and molecular electronics, and catalysis. Here we report crystal structures and theoretical analysis of three Ag...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms3422
更新日期:2013-01-01 00:00:00
abstract::Biodiversity changes are lagging behind current climate warming. The underlying determinants of this climatic debt are unknown and yet critical to understand the impacts of climate change on the present biota and improve forecasts of biodiversity changes. Here we assess determinants of climatic debt accumulated in Fre...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms12643
更新日期:2016-08-26 00:00:00
abstract::The gating mechanism of transmembrane ion channels is crucial for understanding how these proteins control ion flow across membranes in various physiological processes. Big potassium (BK) channels are particularly interesting with large single-channel conductance and dual regulation by membrane voltage and intracellul...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-05970-3
更新日期:2018-08-24 00:00:00
abstract::Lithium- and sodium-rich layered transition-metal oxides have recently been attracting significant interest because of their large capacity achieved by additional oxygen-redox reactions. However, layered transition-metal oxides exhibit structural degradation such as cation migration, layer exfoliation or cracks upon d...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-09409-1
更新日期:2019-05-16 00:00:00
abstract::Understanding and predicting radiation damage evolution in complex materials is crucial for developing next-generation nuclear energy sources. Here, using a combination of ion beam irradiation, transmission electron microscopy and X-ray diffraction, we show that, contrary to the behaviour observed in pyrochlores, the ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms9750
更新日期:2015-10-29 00:00:00
abstract::Exercise induces expression of the myokine irisin, which is known to promote browning of white adipose tissue and has been shown to mediate beneficial effects following exercise. Here we show that irisin induces expression of a number of pro-myogenic and exercise response genes in myotubes. Irisin increases myogenic d...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-01131-0
更新日期:2017-10-24 00:00:00
abstract::Assembly and maturation of synapses at the Drosophila neuromuscular junction (NMJ) depend on trans-synaptic neurexin/neuroligin signalling, which is promoted by the scaffolding protein Syd-1 binding to neurexin. Here we report that the scaffold protein spinophilin binds to the C-terminal portion of neurexin and is nee...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms9362
更新日期:2015-10-16 00:00:00
abstract::Genomic evolution, transmission and pathogenesis of Streptococcus pneumoniae, an opportunistic human-adapted pathogen, is driven principally by nasopharyngeal carriage. However, little is known about genomic changes during natural colonisation. Here, we use whole-genome sequencing to investigate within-host microevolu...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-17327-w
更新日期:2020-07-10 00:00:00
abstract::Thanks to the nature of strong programmability, field-programmable gate arrays (FPGAs) have been playing a significant role in signal processing and control. With the explosive growth in digital data, big data analytics becomes an important emerging field, in which FPGAs are a major player. However, the computational ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-14249-0
更新日期:2020-01-21 00:00:00
abstract::Most estimates of the burden of malaria are based on its direct impacts; however, its true burden is likely to be greater because of its wider effects on overall health. Here we estimate the indirect impact of malaria on children's health in a case-control study, using the sickle cell trait (HbAS), a condition associa...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-08775-0
更新日期:2019-02-20 00:00:00
abstract::Selective activation of dopamine D1 receptors (D1Rs) has been pursued for 40 years as a therapeutic strategy for neurologic and psychiatric diseases due to the fundamental role of D1Rs in motor function, reward processing, and cognition. All known D1R-selective agonists are catechols, which are rapidly metabolized and...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-02776-7
更新日期:2018-02-14 00:00:00
abstract::Human APOBEC3A (A3A) cytidine deaminase is a host enzyme that can introduce mutations into chromosomal DNA. As APOBEC3B (A3B) encodes a C-terminal catalytic domain ~91% identical to A3A, we examined its genotoxic potential as well as that of a highly prevalent chimaeric A3A-A3B deletion allele (ΔA3B), which is linked ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms6129
更新日期:2014-10-09 00:00:00
abstract::Chromosomal rearrangements are essential events in the pathogenesis of both malignant and nonmalignant disorders, yet the factors affecting their formation are incompletely understood. Here we develop a zinc-finger nuclease translocation reporter and screen for factors that modulate rearrangements in human cells. We i...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms15110
更新日期:2017-04-27 00:00:00
abstract::Covalent organic frameworks (COFs) as drug-delivery carriers have been mostly evaluated in vitro due to the lack of COFs nanocarriers that are suitable for in vivo studies. Here we develop a series of water-dispersible polymer-COF nanocomposites through the assembly of polyethylene-glycol-modified monofunctional curcu...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-04910-5
更新日期:2018-07-17 00:00:00
abstract::Carbon-based three-dimensional aerographite networks, built from interconnected hollow tubular tetrapods of multilayer graphene, are ultra-lightweight materials recently discovered and ideal for advanced multifunctional applications. In order to predict the bulk mechanical behaviour of networks it is very important to...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms14982
更新日期:2017-04-12 00:00:00
abstract::A high-sugar diet has been associated with reduced lifespan in organisms ranging from worms to mammals. However, the mechanisms underlying the harmful effects of glucose are poorly understood. Here we establish a causative relationship between endogenous glucose storage in the form of glycogen, resistance to oxidative...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms15868
更新日期:2017-06-19 00:00:00
abstract::Hybrid halide perovskite solar cells were first demonstrated in 2009 with cell efficiency quickly soaring from below 10% to more than 23% in a few years. Halide perovskites have the desirable processing simplicity but are very fragile when exposed to water and heat. This fragility represents a great challenge for the ...
journal_title:Nature communications
pub_type: 杂志文章,评审
doi:10.1038/s41467-018-07382-9
更新日期:2018-11-28 00:00:00
abstract::Thousands of tons of isotopic mixtures are processed annually for heavy-water production and tritium decontamination. The existing technologies remain extremely energy intensive and require large capital investments. New approaches are needed to reduce the industry's footprint. Recently, micrometre-size crystals of gr...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms15215
更新日期:2017-05-09 00:00:00
abstract::Among the perovskite oxide family, KTaO3 (KTO) has recently attracted considerable interest as a possible system for the realization of the Rashba effect. In this work, we report a novel conducting interface by placing KTO with another insulator, LaVO3 (LVO) and report planar Hall effect (PHE) and anisotropic magnetor...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-14689-z
更新日期:2020-02-13 00:00:00