Planar Hall effect and anisotropic magnetoresistance in polar-polar interface of LaVO3-KTaO3 with strong spin-orbit coupling.

abstract：:Intracranial aneurysm is a common life-threatening disease. Computed tomography angiography is recommended as the standard diagnosis tool; yet, interpretation can be time-consuming and challenging. We present a specific deep-learning-based model trained on 1,177 digital subtraction angiography verified bone-removal co...

journal_title：Nature communications

authors： Shi Z,Miao C,Schoepf UJ,Savage RH,Dargis DM,Pan C,Chai X,Li XL,Xia S,Zhang X,Gu Y,Zhang Y,Hu B,Xu W,Zhou C,Luo S,Wang H,Mao L,Liang K,Wen L,Zhou L,Yu Y,Lu GM,Zhang LJ

更新日期：2020-11-30 00:00:00

abstract：:In patients with damage to the primary visual cortex (V1), residual vision can guide goal-directed movements to targets in the blind field without awareness. This phenomenon has been termed blindsight, and its neural mechanisms are controversial. There should be visual pathways to the higher visual cortices bypassing ...

journal_title：Nature communications

authors： Kinoshita M,Kato R,Isa K,Kobayashi K,Kobayashi K,Onoe H,Isa T

更新日期：2019-01-11 00:00:00

abstract：:Radiofrequency switches are critical components in wireless communication systems and consumer electronics. Emerging devices include switches based on microelectromechanical systems and phase-change materials. However, these devices suffer from disadvantages such as large physical dimensions and high actuation voltage...

journal_title：Nature communications

authors： Pi S,Ghadiri-Sadrabadi M,Bardin JC,Xia Q

更新日期：2015-06-25 00:00:00

abstract：:Mutations in patatin-like phospholipase domain-containing 1 (PNPLA1) cause autosomal recessive congenital ichthyosis, but the mechanism involved remains unclear. Here we show that PNPLA1, an enzyme expressed in differentiated keratinocytes, plays a crucial role in the biosynthesis of ω-O-acylceramide, a lipid componen...

journal_title：Nature communications

authors： Hirabayashi T,Anjo T,Kaneko A,Senoo Y,Shibata A,Takama H,Yokoyama K,Nishito Y,Ono T,Taya C,Muramatsu K,Fukami K,Muñoz-Garcia A,Brash AR,Ikeda K,Arita M,Akiyama M,Murakami M

更新日期：2017-03-01 00:00:00

abstract：:Pompe disease, a rare lysosomal storage disease caused by deficiency of the lysosomal acid α-glucosidase (GAA), is characterized by glycogen accumulation, triggering severe secondary cellular damage and resulting in progressive motor handicap and premature death. Numerous disease-causing mutations in the gaa gene have...

journal_title：Nature communications

authors： Roig-Zamboni V,Cobucci-Ponzano B,Iacono R,Ferrara MC,Germany S,Bourne Y,Parenti G,Moracci M,Sulzenbacher G

更新日期：2017-10-24 00:00:00

abstract：:Meso/micro-porous solids, such as zeolites, are complex materials used in an impressive range of applications. Here we photo-polymerized ethylene using non-catalytic high-pressure techniques at 0.5-1.5 GPa under ultraviolet (351-364 nm) irradiation on a sub-nanometre scale in the channels of a pure SiO2 zeolite, silic...

journal_title：Nature communications

authors： Santoro M,Gorelli FA,Bini R,Haines J,van der Lee A

更新日期：2013-01-01 00:00:00

abstract：:Compartmentalization of the gut microbiota is thought to be important to system function, but the extent of spatial organization in the gut ecosystem remains poorly understood. Here, we profile the murine colonic microbiota along longitudinal and lateral axes using laser capture microdissection. We found fine-scale sp...

journal_title：Nature communications

authors： Riva A,Kuzyk O,Forsberg E,Siuzdak G,Pfann C,Herbold C,Daims H,Loy A,Warth B,Berry D

更新日期：2019-09-25 00:00:00

abstract：:The widespread CsrA/RsmA protein regulators repress translation by binding GGA motifs in bacterial mRNAs. CsrA activity is primarily controlled through sequestration by multiple small regulatory RNAs. Here we investigate CsrA activity control in the absence of antagonizing small RNAs by examining the CsrA regulon in t...

journal_title：Nature communications

authors： Dugar G,Svensson SL,Bischler T,Wäldchen S,Reinhardt R,Sauer M,Sharma CM

更新日期：2016-05-27 00:00:00

abstract：:Mitochondrial DNA (mtDNA) deletions are associated with mitochondrial disease, and also accumulate during normal human ageing. The mechanisms underlying mtDNA deletions remain unknown although several models have been proposed. Here we use deep sequencing to characterize abundant mtDNA deletions in patients with mutat...

journal_title：Nature communications

authors： Persson Ö,Muthukumar Y,Basu S,Jenninger L,Uhler JP,Berglund AK,McFarland R,Taylor RW,Gustafsson CM,Larsson E,Falkenberg M

更新日期：2019-02-15 00:00:00

abstract：:Ultra-small, magic-sized metal nanoclusters represent an important new class of materials with properties between molecules and particles. However, their small size challenges the conventional methods for structure characterization. Here we present the structure of ultra-stable Au144(SR)60 magic-sized nanoclusters obt...

journal_title：Nature communications

authors： Jensen KM,Juhas P,Tofanelli MA,Heinecke CL,Vaughan G,Ackerson CJ,Billinge SJ

更新日期：2016-06-14 00:00:00

abstract：:The activation of a neuronal ensemble in the central nucleus of the amygdala (CeA) during alcohol withdrawal has been hypothesized to induce high levels of alcohol drinking in dependent rats. In the present study we describe that the CeA neuronal ensemble that is activated by withdrawal from chronic alcohol exposure c...

journal_title：Nature communications

authors： de Guglielmo G,Kallupi M,Pomrenze MB,Crawford E,Simpson S,Schweitzer P,Koob GF,Messing RO,George O

更新日期：2019-03-18 00:00:00

abstract：:Reduced-dimensional perovskites are attractive light-emitting materials due to their efficient luminescence, color purity, tunable bandgap, and structural diversity. A major limitation in perovskite light-emitting diodes is their limited operational stability. Here we demonstrate that rapid photodegradation arises fro...

journal_title：Nature communications

authors： Na Quan L,Ma D,Zhao Y,Voznyy O,Yuan H,Bladt E,Pan J,García de Arquer FP,Sabatini R,Piontkowski Z,Emwas AH,Todorović P,Quintero-Bermudez R,Walters G,Fan JZ,Liu M,Tan H,Saidaminov MI,Gao L,Li Y,Anjum DH,Wei N,Ta

更新日期：2020-01-10 00:00:00

abstract：:Ultrasound sensors have wide applications across science and technology. However, improved sensitivity is required for both miniaturisation and increased spatial resolution. Here, we introduce cavity optomechanical ultrasound sensing, where dual optical and mechanical resonances enhance the ultrasound signal. We achie...

journal_title：Nature communications

authors： Basiri-Esfahani S,Armin A,Forstner S,Bowen WP

更新日期：2019-01-10 00:00:00

abstract：:Formation of amyloid-beta (Aβ) oligomer pores in the membrane of neurons has been proposed to explain neurotoxicity in Alzheimer's disease (AD). Here, we present the three-dimensional structure of an Aβ oligomer formed in a membrane mimicking environment, namely an Aβ(1-42) tetramer, which comprises a six stranded β-s...

journal_title：Nature communications

authors： Ciudad S,Puig E,Botzanowski T,Meigooni M,Arango AS,Do J,Mayzel M,Bayoumi M,Chaignepain S,Maglia G,Cianferani S,Orekhov V,Tajkhorshid E,Bardiaux B,Carulla N

更新日期：2020-06-15 00:00:00

abstract：:Linking microbial metabolomics and carbon sequestration in the ocean via refractory organic molecules has been hampered by the chemical complexity of dissolved organic matter (DOM). Here, using bioassay experiments and ultra-high resolution metabolic profiling, we demonstrate that marine bacteria rapidly utilize simpl...

journal_title：Nature communications

authors： Lechtenfeld OJ,Hertkorn N,Shen Y,Witt M,Benner R

更新日期：2015-03-31 00:00:00

abstract：:The actin-like protein MreB has been proposed to coordinate the synthesis of the cell wall to determine cell shape in bacteria. MreB is preferentially localized to areas of the cell with specific curved geometries, avoiding the cell poles. It remains unclear whether MreB's curvature preference is regulated by addition...

journal_title：Nature communications

authors： Bratton BP,Shaevitz JW,Gitai Z,Morgenstein RM

更新日期：2018-07-18 00:00:00

abstract：:Nanostructured materials premise to revolutionize the label-free biosensing of analytes for clinical applications, leveraging the deeper interaction between materials and analytes with comparable size. However, when the characteristic dimension of the materials reduces to the nanoscale, the surface functionalization f...

journal_title：Nature communications

authors： Mariani S,Robbiano V,Strambini LM,Debrassi A,Egri G,Dähne L,Barillaro G

更新日期：2018-12-10 00:00:00

abstract：:Different thresholds of Wnt signalling are thought to drive stem cell maintenance, regeneration, differentiation and cancer. However, the principle that oncogenic Wnt signalling could be specifically targeted remains controversial. Here we examine the requirement of BCL9/9l, constituents of the Wnt-enhanceosome, for i...

journal_title：Nature communications

authors： Gay DM,Ridgway RA,Müller M,Hodder MC,Hedley A,Clark W,Leach JD,Jackstadt R,Nixon C,Huels DJ,Campbell AD,Bird TG,Sansom OJ

更新日期：2019-02-13 00:00:00

abstract：:Across phyla, body size is linked to climate. For example, rearing fruit flies at lower temperatures results in bigger body sizes than those observed at higher temperatures. The underlying molecular basis of this effect is poorly understood. Here we provide evidence that the temperature-dependent regulation of Drosoph...

journal_title：Nature communications

authors： Li Q,Gong Z

更新日期：2015-12-09 00:00:00

abstract：:Vesicular photothermal therapy agents (PTAs) are highly desirable in photothermal therapy (PTT) for their excellent light-harvesting ability and versatile hollow compartments. However, up to now, the reported vesicular PTAs are generally self-assembled from small molecules like liposomes, and polymer vesicles have sel...

journal_title：Nature communications

authors： Liu Y,Wang H,Li S,Chen C,Xu L,Huang P,Liu F,Su Y,Qi M,Yu C,Zhou Y

更新日期：2020-04-07 00:00:00

abstract：:The high photon flux and femtosecond pulse duration of hard X-ray free-electron lasers have spurred a large variety of novel and fascinating experiments in physical, chemical and biological sciences. Many of these experiments depend fundamentally on a clean, well-defined wavefront. Here we explore the wavefront proper...

journal_title：Nature communications

authors： Rutishauser S,Samoylova L,Krzywinski J,Bunk O,Grünert J,Sinn H,Cammarata M,Fritz DM,David C

更新日期：2012-07-10 00:00:00

abstract：:Hedgehog (Hh) signalling regulates embryonic development and adult tissue homoeostasis. Mutations of its pathway components including Suppressor of Fused (Sufu) and Gli/Ci predispose to cancers and congenital anomalies. The Sufu-Gli protein complex occupies a central position in the vertebrate Hh signalling pathway, e...

journal_title：Nature communications

authors： Zhang Y,Fu L,Qi X,Zhang Z,Xia Y,Jia J,Jiang J,Zhao Y,Wu G

更新日期：2013-01-01 00:00:00

abstract：:Pathological amino-acid substitutions in the amyloid precursor protein (APP) and chemical γ-secretase modulators affect the processing of APP by the γ-secretase complex and the production of the amyloid-beta peptide Aβ42, the accumulation of which is considered causative of Alzheimer's disease. Here we demonstrate tha...

journal_title：Nature communications

authors： Dimitrov M,Alattia JR,Lemmin T,Lehal R,Fligier A,Houacine J,Hussain I,Radtke F,Dal Peraro M,Beher D,Fraering PC

更新日期：2013-01-01 00:00:00

abstract：:Controlling the biodistribution of nanoparticles upon intravenous injection is the key to achieving target specificity. One of the impediments in nanoparticle-based tumor targeting is the inability to limit the trafficking of nanoparticles to liver and other organs leading to smaller accumulated amounts in tumor tissu...

journal_title：Nature communications

authors： Chen F,Ma K,Madajewski B,Zhuang L,Zhang L,Rickert K,Marelli M,Yoo B,Turker MZ,Overholtzer M,Quinn TP,Gonen M,Zanzonico P,Tuesca A,Bowen MA,Norton L,Subramony JA,Wiesner U,Bradbury MS

更新日期：2018-10-08 00:00:00

abstract：:Hox genes have been shown to be essential in vertebrate neural circuit formation and their depletion has resulted in homeotic transformations with neuron loss and miswiring. Here we quantifiy four eye movements in the zebrafish mutant valentino and hox3 knockdowns, and find that contrary to the classical model, oculom...

journal_title：Nature communications

authors： Ma LH,Grove CL,Baker R

更新日期：2014-06-25 00:00:00

abstract：:Glucocorticoids are among the most commonly used anti-inflammatory agents. Despite the enormous efforts in elucidating the glucocorticoid-mediated anti-inflammatory actions, how glucocorticoids tightly control overactive inflammatory response is not fully understood. Here we show that glucocorticoids suppress bacteria...

journal_title：Nature communications

authors： Miyata M,Lee JY,Susuki-Miyata S,Wang WY,Xu H,Kai H,Kobayashi KS,Flavell RA,Li JD

更新日期：2015-01-14 00:00:00

abstract：:Recently, coherent control of the optical response of thin films in standing waves has attracted considerable attention, ranging from applications in excitation-selective spectroscopy and nonlinear optics to all-optical image processing. Here, we show that integration of metamaterial and optical fibre technologies all...

journal_title：Nature communications

authors： Xomalis A,Demirtzioglou I,Plum E,Jung Y,Nalla V,Lacava C,MacDonald KF,Petropoulos P,Richardson DJ,Zheludev NI

更新日期：2018-01-12 00:00:00

abstract：:The gravitational collapse of eruption columns generates ground-hugging pyroclastic density currents (PDCs) with highly variable temperatures, high enough to be a threat for communities surrounding volcanoes. The reasons for such great temperature variability are debated in terms of eruptive versus transport and empla...

journal_title：Nature communications

authors： Trolese M,Cerminara M,Esposti Ongaro T,Giordano G

更新日期：2019-06-06 00:00:00

abstract：:Metagenomic sequencing has greatly improved our ability to profile the composition of environmental and host-associated microbial communities. However, the dependency of most methods on reference genomes, which are currently unavailable for a substantial fraction of microbial species, introduces estimation biases. We ...

journal_title：Nature communications

authors： Milanese A,Mende DR,Paoli L,Salazar G,Ruscheweyh HJ,Cuenca M,Hingamp P,Alves R,Costea PI,Coelho LP,Schmidt TSB,Almeida A,Mitchell AL,Finn RD,Huerta-Cepas J,Bork P,Zeller G,Sunagawa S

更新日期：2019-03-04 00:00:00

abstract：:Angiogenesis is a necessary process for solid tumor growth. Cellular markers for endothelial cell proliferation are potential targets for identifying the vasculature of tumors in homeostasis. Here we customize the behaviors of engineered cells to recognize Apj, a surface marker of the neovascular endothelium, using sy...

journal_title：Nature communications

authors： Wang Z,Wang F,Zhong J,Zhu T,Zheng Y,Zhao T,Xie Q,Ma F,Li R,Tang Q,Xu F,Tian X,Zhu J

更新日期：2020-05-01 00:00:00