Abstract:
:One key route for controlling reaction selectivity in heterogeneous catalysis is to prepare catalysts that exhibit only specific types of sites required for desired product formation. Here we show that alkanethiolate self-assembled monolayers with varying surface densities can be used to tune selectivity to desired hydrogenation and hydrodeoxygenation products during the reaction of furfural on supported palladium catalysts. Vibrational spectroscopic studies demonstrate that the selectivity improvement is achieved by controlling the availability of specific sites for the hydrogenation of furfural on supported palladium catalysts through the selection of an appropriate alkanethiolate. Increasing self-assembled monolayer density by controlling the steric bulk of the organic tail ligand restricts adsorption on terrace sites and dramatically increases selectivity to desired products furfuryl alcohol and methylfuran. This technique of active-site selection simultaneously serves both to enhance selectivity and provide insight into the reaction mechanism.
journal_name
Nat Communjournal_title
Nature communicationsauthors
Pang SH,Schoenbaum CA,Schwartz DK,Medlin JWdoi
10.1038/ncomms3448subject
Has Abstractpub_date
2013-01-01 00:00:00pages
2448issn
2041-1723pii
ncomms3448journal_volume
4pub_type
杂志文章abstract::The efficient selection and isolation of individual cells of interest from a mixed population is desired in many biomedical and clinical applications. Here we show the concept of using photoswitchable semiconducting polymer dots (Pdots) as an optical 'painting' tool, which enables the selection of certain adherent cel...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms11468
更新日期:2016-04-27 00:00:00
abstract::The properties of antihydrogen are expected to be identical to those of hydrogen, and any differences would constitute a profound challenge to the fundamental theories of physics. The most commonly discussed antiatom-based tests of these theories are searches for antihydrogen-hydrogen spectral differences (tests of CP...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms4955
更新日期:2014-06-03 00:00:00
abstract::The quantum noise of the vacuum limits the achievable sensitivity of quantum sensors. In non-classical measurement schemes the noise can be reduced to overcome this limitation. However, schemes based on squeezed or Schrödinger cat states require alignment of the relative phase between the measured interaction and the ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-10576-4
更新日期:2019-07-02 00:00:00
abstract::Low-light-level imaging techniques have application in many diverse fields, ranging from biological sciences to security. A high-quality digital camera based on a multi-megapixel array will typically record an image by collecting of order 10(5) photons per pixel, but by how much could this photon flux be reduced? In t...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms6913
更新日期:2015-01-05 00:00:00
abstract::Breaking time-reversal symmetry enables the realization of non-reciprocal devices, such as isolators and circulators, of fundamental importance in microwave and photonic communication systems. This effect is almost exclusively achieved today through magneto-optical phenomena, which are incompatible with integrated tec...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms3407
更新日期:2013-01-01 00:00:00
abstract::IL-17+ CD4+ T (Th17) cells contribute to the pathogenesis of several human inflammatory diseases. Here we demonstrate that TNF inhibitor (TNFi) drugs induce the anti-inflammatory cytokine IL-10 in CD4+ T cells including IL-17+ CD4+ T cells. TNFi-mediated induction of IL-10 in IL-17+ CD4+ T cells is Treg-/Foxp3-indepen...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms4199
更新日期:2014-01-01 00:00:00
abstract::High strength and high ductility are often mutually exclusive properties for structural metallic materials. This is particularly important for aluminum (Al)-based alloys which are widely commercially employed. Here, we introduce a hierarchical nanostructured Al alloy with a structure of Al nanograins surrounded by nan...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-13087-4
更新日期:2019-11-08 00:00:00
abstract::When our experience violates our predictions, it is adaptive to upregulate encoding of novel information, while down-weighting retrieval of erroneous memory predictions to promote an updated representation of the world. We asked whether mnemonic prediction errors promote hippocampal encoding versus retrieval states, a...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-17287-1
更新日期:2020-07-10 00:00:00
abstract::The Hamiltonian of a closed quantum system governs its complete time evolution. While Hamiltonians with time-variation in a single basis can be recovered using a variety of methods, for more general Hamiltonians the presence of non-commuting terms complicates the reconstruction. Here using a single trapped ion, we pro...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms11218
更新日期:2016-04-14 00:00:00
abstract::Generating a comprehensive map of molecular interactions in living cells is difficult and great efforts are undertaken to infer molecular interactions from large-scale perturbation experiments. Here, we develop the analytical and numerical tools to quantify the fundamental limits for inferring transcriptional networks...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-02489-x
更新日期:2018-01-09 00:00:00
abstract::The Tie receptors with their Angiopoietin ligands act as regulators of angiogenesis and vessel maturation. Tie2 exerts its functions through its supposed endothelial-specific expression. Yet, Tie2 is also expressed at lower levels by pericytes and it has not been unravelled through which mechanisms pericyte Angiopoiet...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms16106
更新日期:2017-07-18 00:00:00
abstract::Topological defects in matter behave collectively to form highly non-trivial structures called topological textures that are characterised by conserved quantities such as the winding number. Here we show that an epitaxial ferroelectric square nanoplate of bismuth ferrite subjected to a large strain gradient (as much a...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-02813-5
更新日期:2018-01-26 00:00:00
abstract::Stability is now a critical factor in the commercialization of organic photovoltaic (OPV) devices. Both extrinsic stability to oxygen and water and intrinsic stability to light and heat in inert conditions must be achieved. Triplet states are known to be problematic in both cases, leading to singlet oxygen production ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-20601-6
更新日期:2021-01-20 00:00:00
abstract::2,3-Dihydrobenzofurans and indolines are common substructures in medicines and natural products. Herein, we describe a method that enables direct access to these core structures from non-conjugated alkenyl amides and ortho-iodoanilines/phenols. Under palladium(II) catalysis this [3 + 2] heteroannulation proceeds in an...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-20182-4
更新日期:2020-12-22 00:00:00
abstract::The survival of viruses partly relies on their ability to self-assemble inside host cells. Although coarse-grained simulations have identified different pathways leading to assembled virions from their components, experimental evidence is severely lacking. Here, we use time-resolved small-angle X-ray scattering to unc...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-05426-8
更新日期:2018-08-06 00:00:00
abstract::How developmental programs reactivate in regeneration is a fundamental question in biology. We addressed this question through the study of Wound Induced Hair follicle Neogenesis (WIHN), an adult organogenesis model where stem cells regenerate de novo hair follicles following deep wounding. The exact mechanism is unce...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-10811-y
更新日期:2019-06-26 00:00:00
abstract::Thermal conductivity of two-dimensional (2D) materials is of interest for energy storage, nanoelectronics and optoelectronics. Here, we report that the thermal conductivity of molybdenum disulfide can be modified by electrochemical intercalation. We observe distinct behaviour for thin films with vertically aligned bas...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms13211
更新日期:2016-10-21 00:00:00
abstract::Parkinson's disease-associated kinase LRRK2 has been linked to IFN type II (IFN-γ) response in infections and to dopaminergic neuronal loss. However, whether and how LRRK2 synergizes with IFN-γ remains unclear. In this study, we employed dopaminergic neurons and microglia differentiated from patient-derived induced pl...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-18755-4
更新日期:2020-10-14 00:00:00
abstract::The shape-controlled synthesis of nanoparticles was established in single-phase solutions by controlling growth directions of crystalline facets on seed nanocrystals kinetically; however, it was difficult to rationally predict and design nanoparticle shapes. Here we introduce a methodology to fabricate nanoparticles i...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms4870
更新日期:2014-05-14 00:00:00
abstract::Combining vapour sensors into arrays is an accepted compromise to mitigate poor selectivity of conventional sensors. Here we show individual nanofabricated sensors that not only selectively detect separate vapours in pristine conditions but also quantify these vapours in mixtures, and when blended with a variable mois...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms8959
更新日期:2015-09-01 00:00:00
abstract::The interband cascade laser differs from any other class of semiconductor laser, conventional or cascaded, in that most of the carriers producing population inversion are generated internally, at semimetallic interfaces within each stage of the active region. Here we present simulations demonstrating that all previous...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms1595
更新日期:2011-12-13 00:00:00
abstract::The central issues for understanding iron (Fe)-based superconductors are the symmetry and structure of the superconducting gap. So far the experimental data and theoretical models have been highly controversial. Some experiments favor two or more constant or nearly constant gaps, others indicate strong anisotropy and ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms1115
更新日期:2010-11-16 00:00:00
abstract::The stem cell pluripotency factor Oct4 serves a critical protective role during atherosclerotic plaque development by promoting smooth muscle cell (SMC) investment. Here, we show using Myh11-CreERT2 lineage-tracing with inducible SMC and pericyte (SMC-P) knockout of Oct4 that Oct4 regulates perivascular cell migration...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-08811-z
更新日期:2019-02-27 00:00:00
abstract::Ever since its discovery around a decade ago, all-optical magnetization switching (AOS) using femtosecond laser pulses has shown potential for future data storage and logic devices. In particular, single pulse helicity independent AOS in certain ferrimagnetic alloys and multilayers is highly efficient and ultrafast. H...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-17676-6
更新日期:2020-07-31 00:00:00
abstract::Leads are a key feature of the Arctic ice pack during the winter owing to their substantial contribution to the surface energy balance. According to the present understanding, enhanced heat and moisture fluxes from high lead concentrations tend to produce more boundary layer clouds. However, described here in our comp...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-14074-5
更新日期:2020-01-10 00:00:00
abstract::DNA methylation plays important roles in prokaryotes, and their genomic landscapes-prokaryotic epigenomes-have recently begun to be disclosed. However, our knowledge of prokaryotic methylation systems is focused on those of culturable microbes, which are rare in nature. Here, we used single-molecule real-time and circ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-08103-y
更新日期:2019-01-11 00:00:00
abstract::The ice- and organic-rich permafrost of the northeast Siberian Arctic lowlands (NESAL) has been projected to remain stable beyond 2100, even under pessimistic climate warming scenarios. However, the numerical models used for these projections lack processes which induce widespread landscape change termed thermokarst, ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-15725-8
更新日期:2020-05-04 00:00:00
abstract::Perceptual decisions are accompanied by feelings of confidence that reflect the likelihood that the decision was correct. Here we aim to clarify the relationship between perception and confidence by studying the same perceptual task across three different confidence contexts. Human observers were asked to categorize t...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-15561-w
更新日期:2020-04-09 00:00:00
abstract::The spatial organization of chromosomes has key functional roles, yet how chromosomes fold remains poorly understood at the single-molecule level. Here, we employ models of polymer physics to investigate DNA loci in human HCT116 and IMR90 wild-type and cohesin depleted cells. Model predictions on single-molecule struc...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-17141-4
更新日期:2020-07-03 00:00:00
abstract::It has been postulated that synaptic potentiation during waking is offset by a homoeostatic reduction in net synaptic strength during sleep. However, molecular mechanisms to support such a process are lacking. Here we demonstrate that deficiencies in the RNA-editing gene Adar increase sleep due to synaptic dysfunction...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms10512
更新日期:2016-01-27 00:00:00