Abstract：
:Topological defects in matter behave collectively to form highly non-trivial structures called topological textures that are characterised by conserved quantities such as the winding number. Here we show that an epitaxial ferroelectric square nanoplate of bismuth ferrite subjected to a large strain gradient (as much as 105 m-1) associated with misfit strain relaxation enables five discrete levels for the ferroelectric topological invariant of the entire system because of its peculiar radial quadrant domain texture and its inherent domain wall chirality. The total winding number of the topological texture can be configured from - 1 to 3 by selective non-local electric switching of the quadrant domains. By using angle-resolved piezoresponse force microscopy in conjunction with local winding number analysis, we directly identify the existence of vortices and anti-vortices, observe pair creation and annihilation and manipulate the net number of vortices. Our findings offer a useful concept for multi-level topological defect memory.
journal_name
Nat Communjournal_title
Nature communicationsauthors
Kim KE,Jeong S,Chu K,Lee JH,Kim GY,Xue F,Koo TY,Chen LQ,Choi SY,Ramesh R,Yang CHdoi
10.1038/s41467-017-02813-5subject
Has Abstractpub_date
2018-01-26 00:00:00pages
403issue
1issn
2041-1723pii
10.1038/s41467-017-02813-5journal_volume
9pub_type
杂志文章abstract：:The original version of this Article omitted a declaration from the Competing Interests statement, which should have included the following: 'A patent has been applied for by Emory University with F.E.L, I.S. and D.C. N. as named inventors. The patent application number is PCT/US2016/036650'. This has now been correct...
journal_title：Nature communications
pub_type： 杂志文章,已发布勘误
doi：10.1038/s41467-019-08400-0
更新日期：2019-01-17 00:00:00
abstract：:Despite centuries of research, much about the barbarian migrations that took place between the fourth and sixth centuries in Europe remains hotly debated. To better understand this key era that marks the dawn of modern European societies, we obtained ancient genomic DNA from 63 samples from two cemeteries (from Hungar...
journal_title：Nature communications
pub_type： 历史文章,杂志文章
doi：10.1038/s41467-018-06024-4
更新日期：2018-09-11 00:00:00
abstract：:The radioactive element astatine exists only in trace amounts in nature. Its properties can therefore only be explored by study of the minute quantities of artificially produced isotopes or by performing theoretical calculations. One of the most important properties influencing the chemical behaviour is the energy req...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms2819
更新日期：2013-01-01 00:00:00
abstract：:Denervation of skeletal muscles induces severe muscle atrophy, which is preceded by cellular alterations such as increased plasma membrane permeability, reduced resting membrane potential and accelerated protein catabolism. The factors that induce these changes remain unknown. Conversely, functional recovery following...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-019-14063-8
更新日期：2020-02-26 00:00:00
abstract：:Molar tooth structures are ptygmatically folded and microspar-filled structures common in early- and mid-Proterozoic (∼2,500-750 million years ago, Ma) subtidal successions, but extremely rare in rocks <750 Ma. Here, on the basis of Mg and S isotopes, we show that molar tooth structures may have formed within sediment...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms10317
更新日期：2016-01-07 00:00:00
abstract：:Chloroplasts communicate information by signalling to nuclei during acclimation to fluctuating light. Several potential operating signals originating from chloroplasts have been proposed, but none have been shown to move to nuclei to modulate gene expression. One proposed signal is hydrogen peroxide (H2O2) produced by...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-017-00074-w
更新日期：2017-06-29 00:00:00
abstract：:In humans, males have lower recombination rates than females over the majority of the genome, but the opposite is usually true near the telomeres. These broad-scale differences have been known for decades, yet little is known about differences at the fine scale. By combining data sets, we have collected recombination ...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms14994
更新日期：2017-04-25 00:00:00
abstract：:Gene-targeted animal models that are generated by injecting Cas9 and sgRNAs into zygotes are often accompanied by undesired double-strand break (DSB)-induced byproducts and random biallelic targeting due to uncontrollable Cas9 targeting activity. Here, we establish a parental allele-specific gene-targeting (Past-CRISP...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-020-18391-y
更新日期：2020-09-14 00:00:00
abstract：:Many porous materials are damaged by pressure exerted by salt crystals growing in their pores. This is a serious issue in conservation science, geomorphology, geotechnical engineering and concrete materials science. In all cases, a central question is whether crystallization pressure will cause damage. Here we present...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms5823
更新日期：2014-09-11 00:00:00
abstract：:Many decisions are based on an internal model of the world. Yet, how such a model is constructed from experience and represented in memory remains unknown. We test the hypothesis that reward shapes memory for sequences of events by retroactively prioritizing memory for objects as a function of their distance from rewa...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-018-07280-0
更新日期：2018-11-20 00:00:00
abstract：:Autophagy is the main homeostatic pathway guiding cytosolic materials for degradation by the lysosome. Maturation of autophagosomes requires their transport towards the perinuclear region of the cell, with key factors underlying both processes still poorly understood. Here we show that transport and positioning of lat...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms11808
更新日期：2016-06-10 00:00:00
abstract：:Histone acetylation is known to affect the speed of seed germination, but the molecular regulatory basis of this remains ambiguous. Here we report that loss of function of two histone deacetylase-binding factors, SWI-INDEPENDENT3 (SIN3)-LIKE1 (SNL1) and SNL2, results in accelerated radicle protrusion and growth during...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms13412
更新日期：2016-11-11 00:00:00
abstract：:Ultraweak light detectors have wide-ranging important applications such as astronomical observation, remote sensing, laser ranging, and night vision. Current commercial ultraweak light detectors are commonly based on a photomultiplier tube or an avalanche photodiode, and they are incompatible with microelectronic devi...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-019-09206-w
更新日期：2019-03-20 00:00:00
abstract：:The responses of atmospheric variability to Tibetan Plateau (TP) snow cover (TPSC) at seasonal, interannual and decadal time scales have been extensively investigated. However, the atmospheric response to faster subseasonal variability of TPSC has been largely ignored. Here, we show that the subseasonal variability of...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-018-06762-5
更新日期：2018-10-12 00:00:00
abstract：:In social species, the phenotype and fitness of an individual depend in part on the genotype of its social partners. However, how these indirect genetic effects affect genotype fitness in competitive situations is poorly understood in animal societies. We therefore studied phenotypic plasticity and fitness of two clon...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms4363
更新日期：2014-01-01 00:00:00
abstract：:Among various flat optical devices, metasurfaces have presented their great ability in efficient manipulation of light fields and have been proposed for variety of devices with specific functionalities. However, due to the high phase dispersion of their building blocks, metasurfaces significantly suffer from large chr...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-017-00166-7
更新日期：2017-08-04 00:00:00
abstract：:Biocatalytic cyclization is highly desirable for efficient synthesis of biologically derived chemical substances, such as the commodity chemicals ε-caprolactam and δ-valerolactam. To identify biocatalysts in lactam biosynthesis, we develop a caprolactam-detecting genetic enzyme screening system (CL-GESS). The Alcalige...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-018-07488-0
更新日期：2018-11-29 00:00:00
abstract：:We propose the concept of universal fiducials based on a set of pre-made semi-synthetic antibodies (sABs) generated by customized phage display selections against the fusion protein BRIL, an engineered variant of apocytochrome b562a. These sABs can bind to BRIL fused either into the loops or termini of different GPCRs...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-020-15363-0
更新日期：2020-03-27 00:00:00
abstract：:A human cell contains hundreds to thousands of mitochondrial DNA (mtDNA) packaged into nucleoids. Currently, the segregation and allocation of nucleoids are thought to be passively determined by mitochondrial fusion and division. Here we provide evidence, using live-cell super-resolution imaging, that nucleoids can be...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-020-18202-4
更新日期：2020-09-08 00:00:00
abstract：:Enhancers are DNA sequences that enable complex temporal and tissue-specific regulation of genes in higher eukaryotes. Although it is not entirely clear how enhancer-promoter interactions can increase gene expression, this proximity has been observed in multiple systems at multiple loci and is thought to be essential ...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-020-20400-z
更新日期：2021-01-11 00:00:00
abstract：:Integrin αVβ8, which like αVβ6 functions to activate TGF-βs, is atypical. Its β8 subunit binds to a distinctive cytoskeleton adaptor and does not exhibit large changes in conformation upon binding to ligand. Here, crystal structures, hydrogen-deuterium exchange dynamics, and affinity measurements on mutants are used t...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-019-13248-5
更新日期：2019-12-02 00:00:00
abstract：:Little is known about how our brains dynamically adapt for efficient functioning. Most previous work has focused on analyzing changes in co-fluctuations between a set of brain regions over several temporal segments of the data. We argue that by collapsing data in space or time, we stand to lose useful information abou...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-018-03664-4
更新日期：2018-04-11 00:00:00
abstract：:The rapid development of scientific CMOS (sCMOS) technology has greatly advanced optical microscopy for biomedical research with superior sensitivity, resolution, field-of-view, and frame rates. However, for sCMOS sensors, the parallel charge-voltage conversion and different responsivity at each pixel induces extra re...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-019-13841-8
更新日期：2020-01-03 00:00:00
abstract：:Insulin resistance is closely associated with obesity and is one of the earliest symptoms of type-2 diabetes. Endothelial cells are involved in the pathogenesis of insulin resistance through their role in insulin delivery and adipose tissue angiogenesis. Here we show that Ecscr (endothelial cell surface expressed chem...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms3389
更新日期：2013-01-01 00:00:00
abstract：:The incidence of non-alcoholic fatty liver disease (NAFLD) increases with age. Cellular senescence refers to a state of irreversible cell-cycle arrest combined with the secretion of proinflammatory cytokines and mitochondrial dysfunction. Senescent cells contribute to age-related tissue degeneration. Here we show that...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms15691
更新日期：2017-06-13 00:00:00
abstract：:Shaping ceramics into complex and intricate geometries using cost-effective processes is desirable in many applications but still remains an open challenge. Inspired by plant seed dispersal units that self-fold on differential swelling, we demonstrate that self-shaping can be implemented in ceramics by programming the...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms13912
更新日期：2016-12-23 00:00:00
abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title：Nature communications
pub_type： 已发布勘误
doi：10.1038/s41467-020-15790-z
更新日期：2020-04-22 00:00:00
abstract：:The transcription factor MafB is expressed by monocytes and macrophages. Efferocytosis (apoptotic cell uptake) by macrophages is important for inhibiting the development of autoimmune diseases, and is greatly reduced in Mafb-deficient macrophages. Here, we show the expression of the first protein in the classical comp...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/s41467-017-01711-0
更新日期：2017-11-22 00:00:00
abstract：:The word 'holography' means a drawing that contains all of the information for light-both amplitude and wavefront. However, because of the insufficient bandwidth of current electronics, the direct measurement of the wavefront of light has not yet been achieved. Though reference-field-assisted interferometric methods h...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms13359
更新日期：2016-10-31 00:00:00
abstract：:The sigma-2 receptor, whose gene remains to be cloned, has been validated as a biomarker for tumour cell proliferation. Here we report the use of a novel photoaffinity probe, WC-21, to identify the sigma-2 receptor-binding site. WC-21, a sigma-2 ligand containing both a photoactive azide moiety and a fluorescein isoth...
journal_title：Nature communications
pub_type： 杂志文章
doi：10.1038/ncomms1386
更新日期：2011-07-05 00:00:00
