Molar tooth carbonates and benthic methane fluxes in Proterozoic oceans.

abstract：:As European heatwaves become more severe, summers in the United Kingdom (UK) are also getting warmer. The UK record temperature of 38.7 °C set in Cambridge in July 2019 prompts the question of whether exceeding 40 °C is now within reach. Here, we show how human influence is increasing the likelihood of exceeding 30, 3...

journal_title：Nature communications

authors： Christidis N,McCarthy M,Stott PA

更新日期：2020-06-30 00:00:00

abstract：:Glucose metabolism is remodeled in cancer, but the global pattern of cancer-specific metabolic changes remains unclear. Here we show, using the comprehensive measurement of metabolic enzymes by large-scale targeted proteomics, that the metabolism both carbon and nitrogen is altered during the malignant progression of ...

journal_title：Nature communications

authors： Kodama M,Oshikawa K,Shimizu H,Yoshioka S,Takahashi M,Izumi Y,Bamba T,Tateishi C,Tomonaga T,Matsumoto M,Nakayama KI

更新日期：2020-03-17 00:00:00

abstract：:Recent crystal structures of G-protein-coupled receptors (GPCRs) have revealed ordered internal water molecules, raising questions about the functional role of those waters for receptor activation that could not be answered by the static structures. Here, we used molecular dynamics simulations to monitor--at atomic an...

journal_title：Nature communications

authors： Yuan S,Filipek S,Palczewski K,Vogel H

更新日期：2014-09-09 00:00:00

abstract：:For many stochastic processes, the probability [Formula: see text] of not-having reached a target in unbounded space up to time [Formula: see text] follows a slow algebraic decay at long times, [Formula: see text]. This is typically the case of symmetric compact (i.e. recurrent) random walks. While the persistence exp...

journal_title：Nature communications

authors： Levernier N,Dolgushev M,Bénichou O,Voituriez R,Guérin T

更新日期：2019-07-05 00:00:00

abstract：:The sensitivity of quantum magnetometer is challenged by control errors and, especially in the solid state, by their short coherence times. Refocusing techniques can overcome these limitations and improve the sensitivity to periodic fields, but they come at the cost of reduced bandwidth and cannot be applied to sense ...

journal_title：Nature communications

authors： Aiello CD,Hirose M,Cappellaro P

更新日期：2013-01-01 00:00:00

abstract：:Understanding marine environmental change and associated biological turnover across the Palaeocene-Eocene Thermal Maximum (PETM; ~56 Ma)-the most pronounced Cenozoic short-term global warming event-is important because of the potential role of the ocean in atmospheric CO2 drawdown, yet proxies for tracing marine produ...

journal_title：Nature communications

authors： Chang L,Harrison RJ,Zeng F,Berndt TA,Roberts AP,Heslop D,Zhao X

更新日期：2018-10-01 00:00:00

abstract：:G protein-coupled receptors (GPCRs) constitute the largest family of cell surface receptors. They can exist and act as dimers, but the requirement of dimers for agonist-induced signal initiation and structural dynamics remains largely unknown. Frizzled 6 (FZD6) is a member of Class F GPCRs, which bind WNT proteins to ...

journal_title：Nature communications

authors： Petersen J,Wright SC,Rodríguez D,Matricon P,Lahav N,Vromen A,Friedler A,Strömqvist J,Wennmalm S,Carlsson J,Schulte G

更新日期：2017-08-09 00:00:00

abstract：:The actin-like protein MreB has been proposed to coordinate the synthesis of the cell wall to determine cell shape in bacteria. MreB is preferentially localized to areas of the cell with specific curved geometries, avoiding the cell poles. It remains unclear whether MreB's curvature preference is regulated by addition...

journal_title：Nature communications

authors： Bratton BP,Shaevitz JW,Gitai Z,Morgenstein RM

更新日期：2018-07-18 00:00:00

abstract：:Lean body mass, consisting mostly of skeletal muscle, is important for healthy aging. We performed a genome-wide association study for whole body (20 cohorts of European ancestry with n = 38,292) and appendicular (arms and legs) lean body mass (n = 28,330) measured using dual energy X-ray absorptiometry or bioelectric...

journal_title：Nature communications

authors： Zillikens MC,Demissie S,Hsu YH,Yerges-Armstrong LM,Chou WC,Stolk L,Livshits G,Broer L,Johnson T,Koller DL,Kutalik Z,Luan J,Malkin I,Ried JS,Smith AV,Thorleifsson G,Vandenput L,Hua Zhao J,Zhang W,Aghdassi A,Åkesson

更新日期：2017-07-19 00:00:00

abstract：:Any experienced event may be encoded and retained in detail as part of our episodic memory, and may also refer and contribute to our generalized knowledge stored in semantic memory. The beginnings of this declarative memory formation are only poorly understood. Even less is known about the interrelation between episod...

journal_title：Nature communications

authors： Friedrich M,Mölle M,Friederici AD,Born J

更新日期：2020-03-10 00:00:00

abstract：:Metal-support interaction is of great significance for catalysis as it can induce charge transfer between metal and support, tame electronic structure of supported metals, impact adsorption energy of reaction intermediates, and eventually change the catalytic performance. Here, we report the metal size-dependent charg...

journal_title：Nature communications

authors： Yan QQ,Wu DX,Chu SQ,Chen ZQ,Lin Y,Chen MX,Zhang J,Wu XJ,Liang HW

更新日期：2019-10-31 00:00:00

abstract：:Ever since its discovery around a decade ago, all-optical magnetization switching (AOS) using femtosecond laser pulses has shown potential for future data storage and logic devices. In particular, single pulse helicity independent AOS in certain ferrimagnetic alloys and multilayers is highly efficient and ultrafast. H...

journal_title：Nature communications

authors： van Hees YLW,van de Meugheuvel P,Koopmans B,Lavrijsen R

更新日期：2020-07-31 00:00:00

abstract：:Eicosapentaenoic acid (EPA), an omega-3 fatty acid, has been widely used to prevent cardiovascular disease (CVD) and treat brain diseases alone or in combination with docosahexaenoic acid (DHA). However, the impact of EPA and DHA supplementation on normal cognitive function and the molecular targets of EPA and DHA are...

journal_title：Nature communications

authors： Liu JH,Wang Q,You QL,Li ZL,Hu NY,Wang Y,Jin ZL,Li SJ,Li XW,Yang JM,Zhu XH,Dai YF,Xu JP,Bai XC,Gao TM

更新日期：2020-10-29 00:00:00

abstract：:Novel methods for information processing are highly desired in our information-driven society. Inspired by the brain's ability to process information, the recently introduced paradigm known as 'reservoir computing' shows that complex networks can efficiently perform computation. Here we introduce a novel architecture ...

journal_title：Nature communications

authors： Appeltant L,Soriano MC,Van der Sande G,Danckaert J,Massar S,Dambre J,Schrauwen B,Mirasso CR,Fischer I

更新日期：2011-09-13 00:00:00

abstract：:Efficient organic light-emitting diodes have been developed using emitters containing rare metals, such as platinum and iridium complexes. However, there is an urgent need to develop emitters composed of more abundant materials. Here we show a thermally activated delayed fluorescence material for organic light-emittin...

journal_title：Nature communications

authors： Kaji H,Suzuki H,Fukushima T,Shizu K,Suzuki K,Kubo S,Komino T,Oiwa H,Suzuki F,Wakamiya A,Murata Y,Adachi C

更新日期：2015-10-19 00:00:00

abstract：:Ufuk Günesdogan was incorrectly associated with Center for Genetic Analysis of Behaviour, National Institute for Physiological Sciences, 5-1 Higashiyama Myodaiji, Okazaki, Aichi 444-8787, Japan and Toshihiro Kobayashi was incorrectly associated with Department of Developmental Biology, University of Göttingen, Götting...

journal_title：Nature communications

authors： Hackett JA,Huang Y,Günesdogan U,Gretarsson KA,Kobayashi T,Surani MA

更新日期：2018-12-11 00:00:00

abstract：:Consolidation stabilizes memory traces after initial encoding. Rodent studies suggest that memory consolidation depends on replay of stimulus-specific activity patterns during fast hippocampal "ripple" oscillations. Here, we measured replay in intracranial electroencephalography recordings in human epilepsy patients, ...

journal_title：Nature communications

authors： Zhang H,Fell J,Axmacher N

更新日期：2018-10-05 00:00:00

abstract：:Experimental and modeling work of neural activity has described recurrent and attractor dynamic patterns in cerebral microcircuits. However, it is still poorly understood whether similar dynamic principles exist or can be generalizable to the large-scale level. Here, we applied dynamic graph theory-based analyses to e...

journal_title：Nature communications

authors： Diez I,Sepulcre J

更新日期：2018-09-24 00:00:00

abstract：:Transition-metal dissolution from cathode materials, manganese in particular, has been held responsible for severe capacity fading in lithium-ion batteries, with the deposition of the transition-metal cations on anode surface, in elemental form or as chelated-complexes, as the main contributor for such degradations. I...

journal_title：Nature communications

authors： Wang C,Xing L,Vatamanu J,Chen Z,Lan G,Li W,Xu K

更新日期：2019-07-31 00:00:00

abstract：:Although the amyloid β-protein (Aβ) is believed to play an initiating role in Alzheimer's disease (AD), the molecular characteristics of the key pathogenic Aβ forms are not well understood. As a result, it has proved difficult to identify optimal agents that target disease-relevant forms of Aβ. Here, we combined the u...

journal_title：Nature communications

authors： Jin M,O'Nuallain B,Hong W,Boyd J,Lagomarsino VN,O'Malley TT,Liu W,Vanderburg CR,Frosch MP,Young-Pearse T,Selkoe DJ,Walsh DM

更新日期：2018-07-11 00:00:00

abstract：:The outcome of molecule-surface collisions can be modified by pre-aligning the molecule; however, experiments accomplishing this are rare because of the difficulty of preparing molecules in aligned quantum states. Here we present a general solution to this problem based on magnetic manipulation of the rotational magne...

journal_title：Nature communications

authors： Godsi O,Corem G,Alkoby Y,Cantin JT,Krems RV,Somers MF,Meyer J,Kroes GJ,Maniv T,Alexandrowicz G

更新日期：2017-05-08 00:00:00

abstract：:Conventional epitaxy of semiconductor films requires a compatible single crystalline substrate and precisely controlled growth conditions, which limit the price competitiveness and versatility of the process. We demonstrate substrate-tolerant nano-heteroepitaxy (NHE) of high-quality formamidinium-lead-tri-iodide (FAPb...

journal_title：Nature communications

authors： Lee JW,Tan S,Han TH,Wang R,Zhang L,Park C,Yoon M,Choi C,Xu M,Liao ME,Lee SJ,Nuryyeva S,Zhu C,Huynh K,Goorsky MS,Huang Y,Pan X,Yang Y

更新日期：2020-11-02 00:00:00

abstract：:Ultralow threshold nanolasers have been sought after as power efficient light sources in photonic integrated circuits. Here a single-cell nanobeam laser with a nanoisland quantum well is proposed and demonstrated. Continuous operation at 1.5 μm is achieved at room temperature with an ultralow lasing threshold of 210 n...

journal_title：Nature communications

authors： Jang H,Karnadi I,Pramudita P,Song JH,Kim KS,Lee YH

更新日期：2015-09-22 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is the most predominant primary malignancy in the liver. Genotoxic and genetic models have revealed that HCC cells are derived from hepatocytes, but where the critical region for tumor foci emergence is and how this transformation occurs are still unclear. Here, hyperpolyploidization of ...

journal_title：Nature communications

authors： Lin H,Huang YS,Fustin JM,Doi M,Chen H,Lai HH,Lin SH,Lee YL,King PC,Hou HS,Chen HW,Young PY,Chao HW

更新日期：2021-01-28 00:00:00

abstract：:In eukaryotic cells, organellar proteome biogenesis is pivotal for cellular function. Chloroplasts contain a complex proteome, the biogenesis of which includes post-translational import of nuclear-encoded proteins. However, the mechanisms determining when and how nascent chloroplast-targeted proteins are sorted in the...

journal_title：Nature communications

authors： Kim DH,Lee JE,Xu ZY,Geem KR,Kwon Y,Park JW,Hwang I

更新日期：2015-04-16 00:00:00

abstract：:Synapse formation is triggered through trans-synaptic interaction between pairs of pre- and postsynaptic adhesion molecules, the specificity of which depends on splice inserts known as 'splice-insert signaling codes'. Receptor protein tyrosine phosphatase δ (PTPδ) can bidirectionally induce pre- and postsynaptic diffe...

journal_title：Nature communications

authors： Yamagata A,Yoshida T,Sato Y,Goto-Ito S,Uemura T,Maeda A,Shiroshima T,Iwasawa-Okamoto S,Mori H,Mishina M,Fukai S

更新日期：2015-04-24 00:00:00

abstract：:High-speed light emitters integrated on silicon chips can enable novel architectures for silicon-based optoelectronics, such as on-chip optical interconnects, and silicon photonics. However, conventional light sources based on compound semiconductors face major challenges for their integration with a silicon-based pla...

journal_title：Nature communications

authors： Miyoshi Y,Fukazawa Y,Amasaka Y,Reckmann R,Yokoi T,Ishida K,Kawahara K,Ago H,Maki H

更新日期：2018-03-29 00:00:00

abstract：:Break-induced replication (BIR) is a DNA double-strand break repair pathway that leads to genomic instabilities similar to those observed in cancer. BIR proceeds by a migrating bubble where asynchrony between leading and lagging strand synthesis leads to accumulation of long single-stranded DNA (ssDNA). It remains unk...

journal_title：Nature communications

authors： Elango R,Sheng Z,Jackson J,DeCata J,Ibrahim Y,Pham NT,Liang DH,Sakofsky CJ,Vindigni A,Lobachev KS,Ira G,Malkova A

更新日期：2017-11-27 00:00:00

abstract：:The effective delivery of therapeutics to disease sites significantly contributes to drug efficacy, toxicity and clearance. Here we demonstrate that clinically approved iron oxide nanoparticles (Ferumoxytol) can be utilized to carry one or multiple drugs. These so called 'nanophores' retain their cargo within their po...

journal_title：Nature communications

authors： Kaittanis C,Shaffer TM,Ogirala A,Santra S,Perez JM,Chiosis G,Li Y,Josephson L,Grimm J

更新日期：2014-03-04 00:00:00

abstract：:Modelling of non-adiabatic dynamics in extended molecular systems and solids is a next frontier of atomistic electronic structure theory. The underlying numerical algorithms should operate only with a few quantities (that can be efficiently obtained from quantum chemistry), provide a controlled approximation (which ca...

journal_title：Nature communications

authors： Gorshkov VN,Tretiak S,Mozyrsky D

更新日期：2013-01-01 00:00:00