Abstract:
:An amendment to this paper has been published and can be accessed via a link at the top of the paper.
journal_name
Nat Communjournal_title
Nature communicationsauthors
Panhans M,Hutsch S,Benduhn J,Schellhammer KS,Nikolis VC,Vangerven T,Vandewal K,Ortmann Fdoi
10.1038/s41467-020-15790-zsubject
Has Abstractpub_date
2020-04-22 00:00:00pages
2047issue
1issn
2041-1723pii
10.1038/s41467-020-15790-zjournal_volume
11pub_type
已发布勘误abstract::Chronic bacterial infections on medical devices, including catheter-associated urinary tract infections (CAUTI), are associated with bacterial biofilm communities that are refractory to antibiotic therapy and resistant to host immunity. Previously, we have shown that Pseudomonas aeruginosa can cause CAUTI by forming a...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-06882-y
更新日期:2018-10-25 00:00:00
abstract::Symmetry-breaking phase transitions are an example of non-equilibrium processes that require real-time treatment, a major challenge in strongly coupled systems without long-lived quasiparticles. Holographic duality provides such an approach by mapping strongly coupled field theories in D dimensions into weakly coupled...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms8406
更新日期:2015-06-23 00:00:00
abstract::Sirtuins regulate numerous important biological processes in mammals, including various age-associated pathophysiologies. However, whether sirtuins are critical to control ageing and longevity in mammals has been controversial. Recent studies have demonstrated critical roles of sirtuins in the brain, especially the hy...
journal_title:Nature communications
pub_type: 杂志文章,评审
doi:10.1038/ncomms5211
更新日期:2014-06-26 00:00:00
abstract::Advanced-stage epithelial ovarian cancers are amongst the most difficult to treat tumors and have proven to be refractory to most cytotoxic, molecularly targeted, or immunotherapeutic approaches. Here, we report that nanoparticle-drug conjugates (NDCs) of monomethyl auristatin E (MMAE) significantly increase loading o...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-02390-7
更新日期:2017-12-18 00:00:00
abstract::Storage of chromatin in restricted nuclear space requires dense packing while ensuring DNA accessibility. Thus, different layers of chromatin organization and epigenetic control mechanisms exist. Genome-wide chromatin interaction maps revealed large interaction domains (TADs) and higher order A and B compartments, ref...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-01724-9
更新日期:2017-11-21 00:00:00
abstract::Tomatoes come in a multitude of shapes and flavors despite a narrow genetic pool. Here, we leverage whole-genome resequencing data available for 602 cultivated and wild accessions to determine the contribution of transposable elements (TEs) to tomato diversity. We identify 6,906 TE insertions polymorphisms (TIPs), whi...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-17874-2
更新日期:2020-08-13 00:00:00
abstract::Field-effect transistors based on carbon nanotubes have been shown to be faster and less energy consuming than their silicon counterparts. However, ensuring these advantages are maintained for integrated circuits is a challenge. Here we demonstrate that a significant reduction in the use of field-effect transistors ca...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms1682
更新日期:2012-02-14 00:00:00
abstract::This corrects the article DOI: 10.1038/ncomms15732. ...
journal_title:Nature communications
pub_type: 杂志文章,已发布勘误
doi:10.1038/ncomms16183
更新日期:2018-03-12 00:00:00
abstract::Since the formulation of the geometric phase by Berry, its relevance has been demonstrated in a large variety of physical systems. However, a geometric phase of the most fundamental spin-1/2 system, the electron spin, has not been observed directly and controlled independently from dynamical phases. Here we report exp...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms3526
更新日期:2013-01-01 00:00:00
abstract::Intermolecular halogen bonds are ideally suited for designing new molecular assemblies because of their strong directionality and the possibility of tuning the interactions by using different types of halogens or molecular moieties. Due to these unique properties of the halogen bonds, numerous areas of application hav...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-19379-4
更新日期:2020-11-06 00:00:00
abstract::Pulsars are rotating neutron stars emitting lighthouse-like beams. Owing to their unique properties, pulsars are a unique astrophysical tool to test general relativity, inform on matter in extreme conditions, and probe galactic magnetic fields. Understanding pulsar physics and emission mechanisms is critical to these ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-11243-4
更新日期:2019-07-19 00:00:00
abstract::SCRaMbLE (Synthetic Chromosome Rearrangement and Modification by LoxP-mediated Evolution) is a genome restructuring technique that can be used in synthetic genomes such as that of Sc2.0, the synthetic yeast genome, which contains hundreds to thousands of strategically positioned loxPsym sites. SCRaMbLE has been used t...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-04157-0
更新日期:2018-05-22 00:00:00
abstract::Diatoms contribute roughly 20% of global primary production, but the factors determining their ability to adapt to global warming are unknown. Here we quantify the capacity for adaptation to warming in the marine diatom Thalassiosira pseudonana. We find that evolutionary rescue under severe (32 °C) warming is slow, bu...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-03906-5
更新日期:2018-04-30 00:00:00
abstract::Zinc-finger nuclease, transcription activator-like effector nuclease and CRISPR (clustered regularly interspaced short palindromic repeats)/Cas9 (CRISPR-associated protein 9) are becoming major tools for genome editing. Importantly, knock-in in several non-rodent species has been finally achieved thanks to these custo...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms10548
更新日期:2016-01-28 00:00:00
abstract::Topologically nontrivial materials host protected edge states associated with the bulk band inversion through the bulk-edge correspondence. Manipulating such edge states is highly desired for developing new functions and devices practically using their dissipation-less nature and spin-momentum locking. Here we introdu...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-16290-w
更新日期:2020-05-18 00:00:00
abstract::The impact of liquid drops on solid surfaces is ubiquitous in nature, and of practical importance in many industrial processes. A drop hitting a flat surface retains a circular symmetry throughout the impact process. Here we show that a drop impinging on Echevaria leaves exhibits asymmetric bouncing dynamics with dist...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms10034
更新日期:2015-11-25 00:00:00
abstract::In the enteric pathogen Salmonella enterica serovar Typhimurium, invasion and motility are coordinated by the master regulator HilD, which induces expression of the type III secretion system 1 (T3SS1) and motility genes. Methyl-accepting chemotaxis proteins (MCPs) detect specific ligands and control the direction of t...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-20558-6
更新日期:2021-01-13 00:00:00
abstract::Metal halide perovskites feature crystalline-like electronic band structures and liquid-like physical properties. The crystal-liquid duality enables optoelectronic devices with unprecedented performance and a unique opportunity to chemically manipulate the structure with low energy input. In this work, we leverage the...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-19009-z
更新日期:2020-10-16 00:00:00
abstract::The development of malaria parasites throughout their various life cycle stages is coordinated by changes in gene expression. We previously showed that the three-dimensional organization of the Plasmodium falciparum genome is strongly associated with gene expression during its replication cycle inside red blood cells....
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-04295-5
更新日期:2018-05-15 00:00:00
abstract::Starting from the gas phase, small clusters can be produced and deposited with huge flexibility with regard to composition, materials choice and cluster size. Despite many advances in experimental characterization, a detailed morphology of such clusters is still lacking. Here we present an atomic scale observation as ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms1887
更新日期:2012-06-12 00:00:00
abstract::Intricate biomineralization processes in molluscs engineer hierarchical structures with meso-, nano- and atomic architectures that give the final composite material exceptional mechanical strength and optical iridescence on the macroscale. This multiscale biological assembly inspires new synthetic routes to complex ma...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms10097
更新日期:2015-12-03 00:00:00
abstract::RNA viruses are characterized by a high mutation rate, a buffer against environmental change. Nevertheless, the means by which random mutation improves viral fitness is not well characterized. Here we report the X-ray crystal structure of the receptor-binding domain (RBD) of the human coronavirus, HCoV-229E, in comple...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-01706-x
更新日期:2017-11-23 00:00:00
abstract::Herein, we report on a significant discovery, namely, the quantitative discharging of reduced graphite forms, such as graphite intercalation compounds, graphenide dispersions and graphenides deposited on surfaces with the simple solvent benzonitrile. Because of its comparatively low reduction potential, benzonitrile i...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms12411
更新日期:2016-08-10 00:00:00
abstract::Long-range chromatin interactions are important for transcriptional regulation of genes, many of which are related to complex agronomics traits. However, the pattern of three-dimensional chromatin interactions remains unclear in plants. Here we report the generation of chromatin interaction analysis by paired-end tag ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-10603-4
更新日期:2019-06-14 00:00:00
abstract::Targeting the vasculature remains a promising approach for treating solid tumours; however, the mechanisms of tumour neovascularization are diverse and complex. Here we uncover a new subpopulation of melanoma cells that express the vascular cell adhesion molecule PECAM1, but not VEGFR-2, and participate in a PECAM1-de...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms6200
更新日期:2014-10-22 00:00:00
abstract::Across phyla, body size is linked to climate. For example, rearing fruit flies at lower temperatures results in bigger body sizes than those observed at higher temperatures. The underlying molecular basis of this effect is poorly understood. Here we provide evidence that the temperature-dependent regulation of Drosoph...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms10083
更新日期:2015-12-09 00:00:00
abstract::Photoswitchable molecules and nanoparticles constitute superior biosensors for a wide range of industrial, research and biomedical applications. Rendered reversible by spontaneous or deterministic means, such probes facilitate many of the techniques in fluorescence microscopy that surpass the optical resolution dictat...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms7036
更新日期:2015-01-16 00:00:00
abstract::Momentum and spin represent fundamental dynamic properties of quantum particles and fields. In particular, propagating optical waves (photons) carry momentum and longitudinal spin determined by the wave vector and circular polarization, respectively. Here we show that exactly the opposite can be the case for evanescen...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms4300
更新日期:2014-03-06 00:00:00
abstract::Perisomatic inhibition of pyramidal neurons is established by fast-spiking, parvalbumin-expressing interneurons (PV cells). Failure to assemble adequate perisomatic inhibition is thought to underlie the aetiology of neurological dysfunction in seizures, autism spectrum disorders and schizophrenia. Here we show that in...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms12829
更新日期:2016-09-09 00:00:00
abstract::Laser powder bed fusion additive manufacturing is an emerging 3D printing technique for the fabrication of advanced metal components. Widespread adoption of it and similar additive technologies is hampered by poor understanding of laser-metal interactions under such extreme thermal regimes. Here, we elucidate the mech...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-10009-2
更新日期:2019-04-30 00:00:00