Dynamics of pore formation during laser powder bed fusion additive manufacturing.

abstract：:Prolonged cell survival occurs through the expression of specific protein isoforms generated by alternate splicing of mRNA precursors in cancer cells. How alternate splicing regulates tumor development and resistance to targeted therapies in cancer remain poorly understood. Here we show that RNF113A, whose loss-of-fun...

journal_title：Nature communications

authors： Shostak K,Jiang Z,Charloteaux B,Mayer A,Habraken Y,Tharun L,Klein S,Xu X,Duong HQ,Vislovukh A,Close P,Florin A,Rambow F,Marine JC,Büttner R,Chariot A

更新日期：2020-03-09 00:00:00

abstract：:AMP-activated protein kinase (AMPK) plays a key role in controlling energy metabolism in response to physiological and nutritional status. Although AMPK activation has been proposed as a promising molecular target for treating obesity and its related comorbidities, the use of pharmacological AMPK activators has been m...

journal_title：Nature communications

authors： Lee MS,Han HJ,Han SY,Kim IY,Chae S,Lee CS,Kim SE,Yoon SG,Park JW,Kim JH,Shin S,Jeong M,Ko A,Lee HY,Oh KJ,Lee YH,Bae KH,Koo SH,Kim JW,Seong JK,Hwang D,Song J

更新日期：2018-08-24 00:00:00

abstract：:Embedding tunable quantum emitters in a photonic bandgap structure enables control of dissipative and dispersive interactions between emitters and their photonic bath. Operation in the transmission band, outside the gap, allows for studying waveguide quantum electrodynamics in the slow-light regime. Alternatively, tun...

journal_title：Nature communications

authors： Mirhosseini M,Kim E,Ferreira VS,Kalaee M,Sipahigil A,Keller AJ,Painter O

更新日期：2018-09-12 00:00:00

abstract：:Genetic mutations predispose the serine protease inhibitor α1-antitrypsin to misfolding and polymerisation within hepatocytes, causing liver disease and chronic obstructive pulmonary disease. This misfolding occurs via a transiently populated intermediate state, but our structural understanding of this process is limi...

journal_title：Nature communications

authors： Jagger AM,Waudby CA,Irving JA,Christodoulou J,Lomas DA

更新日期：2020-12-11 00:00:00

abstract：:The word 'holography' means a drawing that contains all of the information for light-both amplitude and wavefront. However, because of the insufficient bandwidth of current electronics, the direct measurement of the wavefront of light has not yet been achieved. Though reference-field-assisted interferometric methods h...

journal_title：Nature communications

authors： Lee K,Park Y

更新日期：2016-10-31 00:00:00

abstract：:Denervation of skeletal muscles induces severe muscle atrophy, which is preceded by cellular alterations such as increased plasma membrane permeability, reduced resting membrane potential and accelerated protein catabolism. The factors that induce these changes remain unknown. Conversely, functional recovery following...

journal_title：Nature communications

authors： Cisterna BA,Vargas AA,Puebla C,Fernández P,Escamilla R,Lagos CF,Matus MF,Vilos C,Cea LA,Barnafi E,Gaete H,Escobar DF,Cardozo CP,Sáez JC

更新日期：2020-02-26 00:00:00

abstract：:Graphene nanoscrolls are Archimedean-type spirals formed by rolling single-layer graphene sheets. Their unique structure makes them conceptually interesting and understanding their formation gives important information on the manipulation and characteristics of various carbon nanostructures. Here we report a 100% effi...

journal_title：Nature communications

authors： Sharifi T,Gracia-Espino E,Barzegar HR,Jia X,Nitze F,Hu G,Nordblad P,Tai CW,Wågberg T

更新日期：2013-01-01 00:00:00

abstract：:The dynamics of an order parameter's amplitude and phase determines the collective behaviour of novel states emerging in complex materials. Time- and momentum-resolved pump-probe spectroscopy, by virtue of measuring material properties at atomic and electronic time scales out of equilibrium, can decouple entangled deg...

journal_title：Nature communications

authors： Lee WS,Chuang YD,Moore RG,Zhu Y,Patthey L,Trigo M,Lu DH,Kirchmann PS,Krupin O,Yi M,Langner M,Huse N,Robinson JS,Chen Y,Zhou SY,Coslovich G,Huber B,Reis DA,Kaindl RA,Schoenlein RW,Doering D,Denes P,Schlotter WF

更新日期：2012-05-15 00:00:00

abstract：:Continuum numerical modeling of dynamic crack propagation has been a great challenge over the past decade. This is particularly the case for anticracks in porous materials, as reported in sedimentary rocks, deep earthquakes, landslides, and snow avalanches, as material inter-penetration further complicates the problem...

journal_title：Nature communications

authors： Gaume J,Gast T,Teran J,van Herwijnen A,Jiang C

更新日期：2018-08-03 00:00:00

abstract：:Hepatitis B virus causes chronic infections in 250 million people worldwide. Chronic hepatitis B virus carriers are at risk of developing fibrosis, cirrhosis, and hepatocellular carcinoma. A prophylactic vaccine exists and currently available antivirals can suppress but rarely cure chronic infections. The study of hep...

journal_title：Nature communications

authors： Winer BY,Huang TS,Pludwinski E,Heller B,Wojcik F,Lipkowitz GE,Parekh A,Cho C,Shrirao A,Muir TW,Novik E,Ploss A

更新日期：2017-07-25 00:00:00

abstract：:Modular and orthogonal genetic logic gates are essential for building robust biologically based digital devices to customize cell signalling in synthetic biology. Here we constructed an orthogonal AND gate in Escherichia coli using a novel hetero-regulation module from Pseudomonas syringae. The device comprises two co...

journal_title：Nature communications

authors： Wang B,Kitney RI,Joly N,Buck M

更新日期：2011-10-18 00:00:00

abstract：:Zinc-finger nuclease, transcription activator-like effector nuclease and CRISPR (clustered regularly interspaced short palindromic repeats)/Cas9 (CRISPR-associated protein 9) are becoming major tools for genome editing. Importantly, knock-in in several non-rodent species has been finally achieved thanks to these custo...

journal_title：Nature communications

authors： Song J,Yang D,Xu J,Zhu T,Chen YE,Zhang J

更新日期：2016-01-28 00:00:00

abstract：:Machines that simultaneously process and store multistate data at one and the same location can provide a new class of fast, powerful and efficient general-purpose computers. We demonstrate the central element of an all-optical calculator, a photonic abacus, which provides multistate compute-and-store operation by int...

journal_title：Nature communications

authors： Feldmann J,Stegmaier M,Gruhler N,Ríos C,Bhaskaran H,Wright CD,Pernice WHP

更新日期：2017-11-02 00:00:00

abstract：:GABAB receptors (GBRs) are key regulators of synaptic release but little is known about trafficking mechanisms that control their presynaptic abundance. We now show that sequence-related epitopes in APP, AJAP-1 and PIANP bind with nanomolar affinities to the N-terminal sushi-domain of presynaptic GBRs. Of the three in...

journal_title：Nature communications

authors： Dinamarca MC,Raveh A,Schneider A,Fritzius T,Früh S,Rem PD,Stawarski M,Lalanne T,Turecek R,Choo M,Besseyrias V,Bildl W,Bentrop D,Staufenbiel M,Gassmann M,Fakler B,Schwenk J,Bettler B

更新日期：2019-03-22 00:00:00

abstract：:Aqueous precipitation of transition metal oxides often proceeds through non-equilibrium phases, whose appearance cannot be anticipated from traditional phase diagrams. Without a precise understanding of which metastable phases form, or their lifetimes, targeted synthesis of specific metal oxides can become a trial-and...

journal_title：Nature communications

authors： Sun W,Kitchaev DA,Kramer D,Ceder G

更新日期：2019-02-04 00:00:00

abstract：:Recent expansion of croplands in the United States has caused widespread conversion of grasslands and other ecosystems with largely unknown consequences for agricultural production and the environment. Here we assess annual land use change 2008-16 and its impacts on crop yields and wildlife habitat. We find that cropl...

journal_title：Nature communications

authors： Lark TJ,Spawn SA,Bougie M,Gibbs HK

更新日期：2020-09-09 00:00:00

abstract：:The recent discovery of high-temperature superconductivity in iron-based compounds has attracted much attention. How to further increase the superconducting transition temperature (T(c)) and how to understand the superconductivity mechanism are two prominent issues facing the current study of iron-based superconductor...

journal_title：Nature communications

authors： Liu D,Zhang W,Mou D,He J,Ou YB,Wang QY,Li Z,Wang L,Zhao L,He S,Peng Y,Liu X,Chen C,Yu L,Liu G,Dong X,Zhang J,Chen C,Xu Z,Hu J,Chen X,Ma X,Xue Q,Zhou XJ

更新日期：2012-07-03 00:00:00

abstract：:A Weyl semimetal possesses spin-polarized band-crossings, called Weyl nodes, connected by topological surface arcs. The low-energy excitations near the crossing points behave the same as massless Weyl fermions, leading to exotic properties like chiral anomaly. To have the transport properties dominated by Weyl fermion...

journal_title：Nature communications

authors： Xu N,Weng HM,Lv BQ,Matt CE,Park J,Bisti F,Strocov VN,Gawryluk D,Pomjakushina E,Conder K,Plumb NC,Radovic M,Autès G,Yazyev OV,Fang Z,Dai X,Qian T,Mesot J,Ding H,Shi M

更新日期：2016-03-17 00:00:00

abstract：:The application of electron microscopy to hydrated biological samples has been limited by high-vacuum operating conditions. Traditional methods utilize harsh and laborious sample dehydration procedures, often leading to structural artefacts and creating difficulties for correlating results with high-resolution fluores...

journal_title：Nature communications

authors： Wojcik M,Hauser M,Li W,Moon S,Xu K

更新日期：2015-06-11 00:00:00

abstract：:Combining vapour sensors into arrays is an accepted compromise to mitigate poor selectivity of conventional sensors. Here we show individual nanofabricated sensors that not only selectively detect separate vapours in pristine conditions but also quantify these vapours in mixtures, and when blended with a variable mois...

journal_title：Nature communications

authors： Potyrailo RA,Bonam RK,Hartley JG,Starkey TA,Vukusic P,Vasudev M,Bunning T,Naik RR,Tang Z,Palacios MA,Larsen M,Le Tarte LA,Grande JC,Zhong S,Deng T

更新日期：2015-09-01 00:00:00

abstract：:Biological cellular structures have inspired many scientific disciplines to design synthetic structures that can mimic their functions. Here, we closely emulate biological cellular structures in a rationally designed synthetic multicellular hybrid ion pump, composed of hydrogen-bonded [EMIM+][TFSI-] ion pairs on the s...

journal_title：Nature communications

authors： Amoli V,Kim JS,Jee E,Chung YS,Kim SY,Koo J,Choi H,Kim Y,Kim DH

更新日期：2019-09-05 00:00:00

abstract：:Preterm infants exhibit different microbiome colonization patterns relative to full-term infants, and it is speculated that the hospital room environment may contribute to infant microbiome development. Here, we present a genome-resolved metagenomic study of microbial genotypes from the gastrointestinal tracts of infa...

journal_title：Nature communications

authors： Brooks B,Olm MR,Firek BA,Baker R,Thomas BC,Morowitz MJ,Banfield JF

更新日期：2017-11-27 00:00:00

abstract：:Monitoring the Earth's stress state plays a role in our understanding of an earthquake's mechanism and in the distribution of hazards. Crustal deformation due to the July 2019 earthquake sequence in Ridgecrest (California) that culminated in a preceding quake of magnitude (M) 6.4 and a subsequent M7.1 quake caused str...

journal_title：Nature communications

authors： Nanjo KZ

更新日期：2020-06-17 00:00:00

abstract：:Plasmids are important members of the bacterial mobile gene pool, and are among the most important contributors to horizontal gene transfer between bacteria. They typically harbour a wide spectrum of host beneficial traits, such as antibiotic resistance, inserted into their backbones. Although these inserted elements ...

journal_title：Nature communications

authors： Norberg P,Bergström M,Jethava V,Dubhashi D,Hermansson M

更新日期：2011-01-01 00:00:00

abstract：:Human-induced ocean acidification and warming alter seawater carbonate chemistry reducing the calcification of reef-building crustose coralline algae (CCA), which has implications for reef stability. However, due to the presence of multiple carbonate minerals with different solubilities in seawater, the algal mineralo...

journal_title：Nature communications

authors： Diaz-Pulido G,Nash MC,Anthony KR,Bender D,Opdyke BN,Reyes-Nivia C,Troitzsch U

更新日期：2014-01-01 00:00:00

abstract：:Knowing which proteins and RNAs directly interact is essential for understanding cellular mechanisms. Unfortunately, discovering such interactions is costly and often unreliable. To overcome these limitations, we developed rec-YnH, a new yeast two and three-hybrid-based screening pipeline capable of detecting interact...

journal_title：Nature communications

authors： Yang JS,Garriga-Canut M,Link N,Carolis C,Broadbent K,Beltran-Sastre V,Serrano L,Maurer SP

更新日期：2018-09-14 00:00:00

abstract：:In the human hematopoietic system, rare self-renewing multipotent long-term hematopoietic stem cells (LT-HSCs) are responsible for the lifelong production of mature blood cells and are the rational target for clinical regenerative therapies. However, the heterogeneity in the hematopoietic stem cell compartment and var...

journal_title：Nature communications

authors： Wagenblast E,Azkanaz M,Smith SA,Shakib L,McLeod JL,Krivdova G,Araújo J,Shultz LD,Gan OI,Dick JE,Lechman ER

更新日期：2019-10-18 00:00:00

abstract：:Mutations in the gene coding for membrane-bound fatty aldehyde dehydrogenase (FALDH) lead to toxic accumulation of lipid species and development of the Sjögren-Larsson Syndrome (SLS), a rare disorder characterized by skin defects and mental retardation. Here, we present the crystallographic structure of human FALDH, t...

journal_title：Nature communications

authors： Keller MA,Zander U,Fuchs JE,Kreutz C,Watschinger K,Mueller T,Golderer G,Liedl KR,Ralser M,Kräutler B,Werner ER,Marquez JA

更新日期：2014-07-22 00:00:00

abstract：:The gyrotropic rotation around the equilibrium position constitutes the fundamental excitation of magnetic vortices in nanostructures. The frequency of this mode varies with material and sample geometry, but is independent of the vortex handedness and its core direction. Here, we demonstrate that this degeneracy is li...

journal_title：Nature communications

authors： Sluka V,Kákay A,Deac AM,Bürgler DE,Schneider CM,Hertel R

更新日期：2015-03-03 00:00:00

abstract：:Genomic alterations occurring during melanoma progression and the resulting genomic heterogeneity between metastatic deposits remain incompletely understood. Analyzing 86 metastatic melanoma deposits from 53 patients with whole-exome sequencing (WES), we show a low branch to trunk mutation ratio and little intermetast...

journal_title：Nature communications

authors： Birkeland E,Zhang S,Poduval D,Geisler J,Nakken S,Vodak D,Meza-Zepeda LA,Hovig E,Myklebost O,Knappskog S,Lønning PE

更新日期：2018-07-10 00:00:00