Abstract:
:Human T-cell leukemia and bovine leukemia viruses have a potential transforming gene, termed X. In addition to the major open reading frame known to encode a functional protein, the X gene harbors another short open reading frame which overlaps this major one. Both of these open reading frames are found on a single spliced X mRNA in a potentially functional form. Circumstantial evidence strongly suggests that they are both translated from the single X mRNA molecule, showing striking similarity to the translation mechanism of an adenovirus Elb gene mRNA. We note that the short open reading frame has the capability to encode a putative nuclear protein with structural features similar to those of an AIDS virus trans-acting protein.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Sagata N,Yasunaga T,Ikawa Ydoi
10.1016/0014-5793(85)80038-7subject
Has Abstractpub_date
1985-11-11 00:00:00pages
37-42issue
1eissn
0014-5793issn
1873-3468pii
0014-5793(85)80038-7journal_volume
192pub_type
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