Antiangiogenic therapy in the management of breast cancer.

abstract：:Carboplatin is a platinum analogue, widely used in the treatment of numerous cancer types including lung, genitourinary and ovarian cancers. It is also used in the adjuvant treatment of human epidermal growth factor receptor 2 positive breast cancer, where a non-anthracycline regimen is preferred. It is considered gen...

journal_title：Asia-Pacific journal of clinical oncology

authors： Turner N,Stewart J,Barnett F,White S

更新日期：2012-09-01 00:00:00

abstract：AIM:Data on lung cancer survival are lacking in developing countries. Our objectives were to describe the survival of our lung cancer patients and to determine independent prognostic factors affecting survival. METHOD:All patients diagnosed with lung cancer from August 2007 to August 2010 were recruited from a single ...

journal_title：Asia-Pacific journal of clinical oncology

authors： How SH,Ng TH,Kuan YC,Jamalludin AR,Fauzi AR

更新日期：2015-09-01 00:00:00

abstract：AIM:Gastric cancer patients are normally treated with oral fluoropyrimidine and cisplatin or oxaliplatin; however, treating patients who also have a gastrointestinal obstruction is often difficult because of their poor oral intake. Instead, a modified (m)FOLFOX-6 regimen is administered, even to patients with gastroint...

journal_title：Asia-Pacific journal of clinical oncology

authors： Yukami H,Terazawa T,Goto M,Aoki M,Asaishi K,Yamaguchi T,Kuwakado S,Kii T,Higuchi K

更新日期：2019-10-01 00:00:00

abstract：AIM:Colorectal cancer (CRC) is one of the most common malignancies worldwide and adjuvant chemotherapy is proven to improve survival in patients with Dukes' C CRC. The purpose of this study was to analyze factors influencing referral to medical oncology in patients with Dukes' C colonic cancer in our institutions. MET...

journal_title：Asia-Pacific journal of clinical oncology

authors： Lu CT,Stephens JH,Rieger NA

更新日期：2010-09-01 00:00:00

abstract：:The COVID-19 pandemic will present a range of challenges to radiation oncology departments. Early data suggest that cancer patients carry a higher than average, but still low absolute risk of hospitalization from COVID-19. The risk of severe events for those who are hospitalized however, is high. Resources for usual c...

journal_title：Asia-Pacific journal of clinical oncology

authors： Horsley PJ,Back M,Lamoury G,Porter B,Booth J,Eade TN

更新日期：2021-02-01 00:00:00

abstract：AIM:While first-line palliative chemotherapy (CT1) improves survival and quality of life in advanced biliary cancer (ABC), there is no randomized evidence to support second-line chemotherapy (CT2) in ABC. We aim to explore to role of CT2 in ABC. METHODS:We performed a retrospective review of all patients who received ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Brungs D,Aghmesheh M,Sjoquist K,Goldstein D

更新日期：2017-10-01 00:00:00

abstract：AIMS:Quality of life (QOL) is important in patients with advanced cancer. The European Organisation for Research and Treatment of Cancer (EORTC) QLQ-C30 is a general QOL tool used in cancer patients. Often, with a large enough sample, statistical significance of changecan be reached, however the clinical significance i...

journal_title：Asia-Pacific journal of clinical oncology

authors： Bedard G,Zeng L,Zhang L,Lauzon N,Holden L,Tsao M,Danjoux C,Barnes E,Sahgal A,Poon M,Chow E

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Anti-HER2 therapy-related cardiotoxicity is well described in the context of clinical trials, particularly in the setting of early stage disease, but there is more limited data in advanced breast cancer and in the real world setting. MATERIAL AND METHODS:A prospectively-maintained registry database with 312...

journal_title：Asia-Pacific journal of clinical oncology

authors： Conduit C,de Boer RH,Lok S,Gibbs P,Malik L,Loh Z,Yeo B,Greenberg S,Devitt B,Lombard J,Nottage M,Collins I,Torres J,Nolan M,Nott L

更新日期：2020-12-01 00:00:00

abstract：:The precise cell types that give rise to tumors and mechanisms that underpin tumor heterogeneity are poorly understood. There is increasing evidence to suggest that diverse solid tumors are hierarchically organized and may be sustained by a distinct subpopulation of cancer stem cells (CSCs). The CSC hypothesis provide...

journal_title：Asia-Pacific journal of clinical oncology

authors： Lindeman GJ,Visvader JE

更新日期：2010-06-01 00:00:00

abstract：AIMS:The optimal maintenance therapy for patients with acute promyelocytic leukemia (APL) who achieved complete remission (CR) and complete consolidation chemotherapy is still controversial. Whether the use of arsenic trioxide (ATO) alone or along with all-trans retinoic acid (ATRA) improves overall survival (OS) or di...

journal_title：Asia-Pacific journal of clinical oncology

authors： Chiang YH,Chang YF,Hsieh RK,Lin J,Chen CG,Lim KH,Lin HC,Chang MC

更新日期：2012-12-01 00:00:00

abstract：AIM:To explore the incidence of subclinical cardiotoxicity in women treated with adjuvant trastuzumab in the early breast cancer setting using cardiac magnetic resonance imaging (cMRI). METHODS:The cardiac function and myocardial tissue characteristics of 25 women who had completed adjuvant trastuzumab therapy greater...

journal_title：Asia-Pacific journal of clinical oncology

authors： Lawley C,Wainwright C,Segelov E,Lynch J,Beith J,McCrohon J

更新日期：2012-03-01 00:00:00

abstract：AIM:The effects of image-guided radiotherapy (IGRT, an advanced RT technology) have been debated in the literature. We compared the outcomes of locally advanced rectal cancer (LARC) patients treated with neoadjuvant concurrent chemoradiotherapy (NCCRT; with vs without IGRT) in a large population-based propensity score ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Li CC,Liang JA,Chen WT,Chien CR

更新日期：2019-10-01 00:00:00

abstract：AIM:Self-expandable metallic stents (SEMS) have been used for palliation in patients with malignant gastroduodenal obstructions. We evaluated clinical outcomes after SEMS placement and identified prognostic factors of SEMS patency, including chemotherapy. METHODS:A review of records of 85 patients with unresectable ga...

journal_title：Asia-Pacific journal of clinical oncology

authors： Cha BH,Lee SH,Kim JE,Yoo JY,Park YS,Kim JW,Jeong SH,Kim N,Lee DH,Hwang JH

更新日期：2013-06-01 00:00:00

abstract：:We report a case of acute inflammatory demyelinating polyradiculoneuropathy (AIDP) that developed in a patient with cholangiocarcinoma after receiving oxaliplatin-based chemotherapy. A 62-year-old man had multiple hypodense lesions with delayed enhancement in the both lobes of the liver on abdominal computed tomograph...

journal_title：Asia-Pacific journal of clinical oncology

authors： Yoon JY,Nam TS,Kim MK,Hwang JE,Shim HJ,Cho SH,Chung IJ,Bae WK

更新日期：2012-06-01 00:00:00

abstract：AIM:To evaluate the distribution of the Oncotype DX Recurrence Score (a validated prognostic/predictive tool in early-stage estrogen-receptor positive [ER+] breast cancer) and its impact on adjuvant treatment decisions in the United Arab Emirates. METHODS:A retrospective analysis of a single-center cohort. RESULTS:Th...

journal_title：Asia-Pacific journal of clinical oncology

authors： Jaafar H,Bashir MA,Taher A,Qawasmeh K,Jaloudi M

更新日期：2014-12-01 00:00:00

abstract：AIM:The role of germline testing in prostate cancer is evolving and knowledge of an individual's genetic profile may be used to guide not only an assessment of their familial risk but also have prognostic and therapeutic implications. Although international guidelines have incorporated recommendations for germline test...

journal_title：Asia-Pacific journal of clinical oncology

authors： Crumbaker M,Wong J,Joshua AM,Spigelman AD

更新日期：2019-08-01 00:00:00

abstract：AIMS:The Australian Institute of Health and Welfare (AIHW) is a major national agency established by the Australian government to provide information and statistics on Australia's health and welfare. The AIHW and the Australasian Association of Cancer Registries collaborate every year to provide updated information on ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Australian Institute of Health and Welfare.

更新日期：2013-09-01 00:00:00

abstract：AIM:To investigate the association between plasma visfatin levels and risk of early and advanced colorectal cancer (CRC). METHODS:In total, 358 CRC patients and 286 controls were enrolled. According to the T factor of the TNM system. cancer patients were divided into two subgroups: early and advanced cancer. Levels of...

journal_title：Asia-Pacific journal of clinical oncology

authors： Chen M,Wang Y,Li Y,Zhao L,Ye S,Wang S,Yu C,Xie H

更新日期：2016-03-01 00:00:00

abstract：:Health literacy refers to one's ability to obtain, process and understand health information and services to enable sound health decision-making. This is an area of increasing importance due to the complexity of the health system, especially in the cancer setting. A certain level of health literacy is required for pat...

journal_title：Asia-Pacific journal of clinical oncology

authors： Koay K,Schofield P,Jefford M

更新日期：2012-03-01 00:00:00

abstract：AIM:Important factors typically associated with prognosis in brain metastases include Karnofsky performance status (KPS), extracranial or cerebellar localization and combination chemotherapy. However, few studies investigated the prognostic role of leptomeningeal metastases (LM) following whole brain radiotherapy (WBRT...

journal_title：Asia-Pacific journal of clinical oncology

authors： Sakaguchi M,Maebayashi T,Aizawa T,Ishibashi N,Saito T

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:MRI and PET/CT scans are the main supportive methods for nasopharyngeal cancer (NPC) for staging and planning. The aim of this study is to compare MRI and PET/CT scanning in terms of survival in patients with NPC who had MRI or PET/CT-simulated radiotherapy planning. METHODS:Pathological diagnosed nonkerati...

journal_title：Asia-Pacific journal of clinical oncology

authors： Gundog M,Basaran H,Dogan S,Abdulrezzak U

更新日期：2021-02-01 00:00:00

abstract：AIM:A viable and sustainable medical oncology profession is integral for meeting the increasing demand for quality cancer care. The aim of this study was to explore the workforce-related experiences, perceptions and career expectations of early-career medical oncologists in Australia. METHODS:A mixed-methods design, i...

journal_title：Asia-Pacific journal of clinical oncology

authors： Wong WKT,Kirby E,Broom A,Sibbritt D,Francis K,Karapetis CS,Karikios D,Harrup R,Lwin Z

更新日期：2018-10-01 00:00:00

abstract：:Resistance to endocrine therapy is a significant therapeutic challenge in the treatment of women with hormone receptor positive (HR+), human epidermal growth factor receptor 2 negative (HER2-) advanced breast cancer. Cyclin-dependent kinase (CDK)4/6 inhibitors in combination with endocrine therapy have been shown to i...

journal_title：Asia-Pacific journal of clinical oncology

authors： Boyle F,Beith J,Burslem K,de Boer R,Hui R,Lim E,McCarthy N,Redfern A,Woodward N

更新日期：2018-10-01 00:00:00

abstract：PURPOSE:To study trends of urological cancers mortalities in Iran between 1990 and 2015 as a part of a larger project named national and subnational burden of diseases, injuries, and risk factors. METHODS:The primary dataset of this project comprises data of national death registration system. Cause-specific mortality...

journal_title：Asia-Pacific journal of clinical oncology

authors： Pishgar F,Amini E,Gohari K,Aminorroaya A,Sheidaei A,Rostamabadi Y,Ebrahimi H,Yoosefi M,Naderimagham S,Rezaei N,Modirian M,Namazi Shabestari A,Kompani F,Farzadfar F

更新日期：2019-04-01 00:00:00

abstract：:It is important to distinguish between tumor recurrence and treatment effects in posttreatment patients with high-grade gliomas. Several imaging modalities have been reported in differentiating between tumor recurrence and treatment effects. However, there were no consistent conclusions between different studies. We p...

journal_title：Asia-Pacific journal of clinical oncology

authors： Wang X,Hu X,Xie P,Li W,Li X,Ma L

更新日期：2015-06-01 00:00:00

abstract：INTRODUCTION:Ki-67 proliferation index (Ki-67 index) is used to quantify cell proliferation during histopathological assessment of various tumors including glioblastoma (GB). AIM:We aimed to assess correlation between Ki-67 index and overall survival in patients with GB and determine a cut-point for Ki-67 index that p...

journal_title：Asia-Pacific journal of clinical oncology

authors： Wong E,Nahar N,Hau E,Varikatt W,Gebski V,Ng T,Jayamohan J,Sundaresan P

更新日期：2019-02-01 00:00:00

abstract：:The association between the rs498872 single nucleotide polymorphism (SNP) and glioma risk has been studied, but these studies have yielded conflicting results. In order to explore this association, we performed a meta-analysis. A comprehensive literature search was performed using PubMed and EMBASE database, with the ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Gao X,Mi Y,Yan A,Sha B,Guo N,Hu Z,Zhang N,Jiang F,Gou X

更新日期：2015-12-01 00:00:00

abstract：AIM:To investigate the role of endothelial cell damage in radiation-induced lung injury. METHODS:A total of 60 male Sprague-Dawley rats were irradiated to the right hemithorax with a single dose of 0, 7.0 or 14.4 Gy. Serial studies were performed before and at 1, 7, 30 and 90 days after radiation, respectively. Pathol...

journal_title：Asia-Pacific journal of clinical oncology

authors： Qiu J,Li J,He TC

更新日期：2011-12-01 00:00:00

abstract：AIM:A proportion of locally advanced rectal cancer patients who receive neoadjuvant chemoradiotherapy (NACRT) are still unresectable. This study was undertaken to assess the outcomes of giving additional chemotherapy to rectal cancer patients with unresectable disease after NACRT. METHODS:Patients with poor response t...

journal_title：Asia-Pacific journal of clinical oncology

authors： Engineer R,Ostwal V,Arya S,Gupta P,Chopra S,Patil P,Jatal S,Saklani A

更新日期：2017-08-01 00:00:00

abstract：AIMS:Currently, the only standard systemic treatment for advanced hepatocellular carcinoma is sorafenib monotherapy. The study was conducted to assess the efficacy and safety of the novel combination of sorafenib and gemcitabine in the treatment of advanced hepatocellular carcinoma. METHODS:Between March 2008 and Octo...

journal_title：Asia-Pacific journal of clinical oncology

authors： Srimuninnimit V,Sriuranpong V,Suwanvecho S

更新日期：2014-09-01 00:00:00