Endoscopic self-expandable metallic stent placement in malignant pyloric or duodenal obstruction: does chemotherapy affect stent patency?

abstract：AIM:Gastric cancer patients are normally treated with oral fluoropyrimidine and cisplatin or oxaliplatin; however, treating patients who also have a gastrointestinal obstruction is often difficult because of their poor oral intake. Instead, a modified (m)FOLFOX-6 regimen is administered, even to patients with gastroint...

journal_title：Asia-Pacific journal of clinical oncology

authors： Yukami H,Terazawa T,Goto M,Aoki M,Asaishi K,Yamaguchi T,Kuwakado S,Kii T,Higuchi K

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Providing appropriate educational resources to patients with head and neck cancer (HNC) is important but challenging. The aim of this study was to determine Australian clinicians' perceptions of currently used HNC information resources. METHODS:A purpose-designed questionnaire was disseminated electronicall...

journal_title：Asia-Pacific journal of clinical oncology

authors： Jabbour J,Wykes J,Milross C,Sundaresan P,Ebrahimi A,Shepherd HL,Dhillon HM,Clark JR

更新日期：2018-10-01 00:00:00

abstract：AIM:Behavioral interventions such as exercise may induce epigenetic changes. Only few studies investigated the effects of exercise on epigenetic alterations in colorectal cancer survivors. The aim of this study was to explore the changes of genome-wide DNA methylation after 6-week exercise training in colorectal cancer...

journal_title：Asia-Pacific journal of clinical oncology

authors： Hwang SH,Kang DW,Lee MK,Byeon JY,Park H,Park DH,Kim KC,Lee ST,Chu SH,Kim NK,Jeon JY

更新日期：2020-10-13 00:00:00

abstract：BACKGROUND:Anti-HER2 therapy-related cardiotoxicity is well described in the context of clinical trials, particularly in the setting of early stage disease, but there is more limited data in advanced breast cancer and in the real world setting. MATERIAL AND METHODS:A prospectively-maintained registry database with 312...

journal_title：Asia-Pacific journal of clinical oncology

authors： Conduit C,de Boer RH,Lok S,Gibbs P,Malik L,Loh Z,Yeo B,Greenberg S,Devitt B,Lombard J,Nottage M,Collins I,Torres J,Nolan M,Nott L

更新日期：2020-12-01 00:00:00

abstract：AIM:To evaluate tumor markers as prognostic factors in patients with metastatic or recurrent gastric cancer receiving first-line chemotherapy. METHODS:Between January 2000 and December 2008, 1178 patients with metastatic or recurrent gastric cancer were assayed for expression of three serum tumor markers, CA 19-9, CA ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Jo JC,Ryu MH,Koo DH,Ryoo BY,Kim HJ,Kim TW,Choi KD,Lee GH,Jung HY,Yook JH,Oh ST,Kim BS,Kim JH,Kang YK

更新日期：2013-12-01 00:00:00

abstract：AIM:Clinical and pharmacokinetic effects of azacitidine in higher-risk myelodysplastic syndromes were established in mainly Caucasian populations. Because of inter-ethnic genotype variability of drug-metabolizing enzymes, it is important to evaluate azacitidine in populations expected to use the drug. METHODS:In this ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Chou WC,Yeh SP,Hsiao LT,Lin SF,Chen YC,Chen TY,Laille E,Galettis A,Dong Q,Songer S,Beach CL

更新日期：2017-10-01 00:00:00

abstract：AIM:Advanced esophagogastric carcinoma has a poor prognosis. Palliative chemotherapy provides a survival advantage and improved quality of life. Epirubicin, cisplatin and continuous infusional 5-fluorouracil (5-FU) (ECF) is a well-established chemotherapy regimen but a continuous chemotherapy infusion is not always fea...

journal_title：Asia-Pacific journal of clinical oncology

authors： Karapetis CS,Cheong KA,Yip D,Strickland AH,Steer C,Marx G,Yip S,Chrystal K,Harper PG

更新日期：2010-12-01 00:00:00

abstract：AIM:Retroperitoneal sarcomas (RPSs) are large, rare tumors. The role of core biopsy for retroperitoneal masses identified by preoperative imaging is unclear and we report the safety and accuracy of core biopsies at a specialized sarcoma unit in Sydney, Australia. METHODS:A retrospective analysis of a prospectively col...

journal_title：Asia-Pacific journal of clinical oncology

authors： Hwang SY,Warrier S,Thompson S,Davidson T,Yang JL,Crowe P

更新日期：2016-03-01 00:00:00

abstract：AIM:Mucositis is a major complication of irradiation in head and neck tumors, the addition of chemotherapy to irradiation may enhance this dose-limiting problem. Licorice is a strong demulcent that had been effectively used in treatment of peptic ulcer. The main purpose of this study was to compare the therapeutic safe...

journal_title：Asia-Pacific journal of clinical oncology

authors： Ghalayani P,Emami H,Pakravan F,Nasr Isfahani M

更新日期：2017-04-01 00:00:00

abstract：AIM:Metadherin (MTDH) is a potential oncogene in tumor development and is highly expressed in various types of human cancers. However, there has been no report on the role of MTDH in bladder cancer. Our aim was to investigate the expression pattern of MTDH in bladder tissue at different clinic pathological stages and e...

journal_title：Asia-Pacific journal of clinical oncology

authors： Zhou J,Li J,Wang Z,Yin C,Zhang W

更新日期：2012-09-01 00:00:00

abstract：AIM:To evaluate predictive factors which associated with oncological outcomes to first-line axitinib for metastatic renal cell carcinoma (mRCC). METHODS:A retrospective chart review was conducted patients who had been treated with axitinib as first-line therapy for the treatment of mRCC from September 2013 to February...

journal_title：Asia-Pacific journal of clinical oncology

authors： Kameda T,Takayama T,Sugihara T,Takeshima S,Yamazaki M,Komatsubara M,Kamei J,Fujisaki A,Ando S,Kurokawa S,Fujimura T

更新日期：2020-08-01 00:00:00

abstract：:Ipilimumab is a human anti-CTLA-4 monoclonal antibody recently approved for the treatment of advanced melanoma. Stimulation of T-cell activity unmasks antitumor activity, but can cause immune-related adverse events. Autoimmune hypophysitis is of particular importance because its presentation can be subtle but life thr...

journal_title：Asia-Pacific journal of clinical oncology

authors： Tiu C,Pezaro C,Davis ID,Grossmann M,Parente P

更新日期：2015-06-01 00:00:00

abstract：AIM:This study examined pathological quality-of-surgery indicators in laparoscopic and open rectal cancer resection specimens. METHODS:Retrospective analysis of consecutive, prospectively recorded laparoscopic (LR) or open (OR) resections for rectal cancer. Indicators included integrity of the perirectal fascial envel...

journal_title：Asia-Pacific journal of clinical oncology

authors： Cheung HYC,Dent OF,Richardson GL,Chan C,Keshava A,Young CJ

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVE:To review the outcomes of metastatic melanoma patients treated with infliximab for severe steroid-refractory colitis secondary to ipilimumab therapy. BACKGROUND:Immune-related colitis is a known potential adverse effect of ipilimumab, that causes significant morbidity and extended hospital stays. There are l...

journal_title：Asia-Pacific journal of clinical oncology

authors： Hillock NT,Heard S,Kichenadasse G,Hill CL,Andrews J

更新日期：2017-10-01 00:00:00

abstract：AIM:Multidisciplinary care is advocated as best practice in cancer care. Relatively little is documented about multidisciplinary team (MDT) meeting functioning, decision making and the use of evidence to support decision making in Australia. This descriptive study aimed to examine team functioning, the role of team mee...

journal_title：Asia-Pacific journal of clinical oncology

authors： Rankin NM,Lai M,Miller D,Beale P,Spigelman A,Prest G,Turley K,Simes J

更新日期：2018-02-01 00:00:00

abstract：AIM:The effects of image-guided radiotherapy (IGRT, an advanced RT technology) have been debated in the literature. We compared the outcomes of locally advanced rectal cancer (LARC) patients treated with neoadjuvant concurrent chemoradiotherapy (NCCRT; with vs without IGRT) in a large population-based propensity score ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Li CC,Liang JA,Chen WT,Chien CR

更新日期：2019-10-01 00:00:00

abstract：AIM:Important factors typically associated with prognosis in brain metastases include Karnofsky performance status (KPS), extracranial or cerebellar localization and combination chemotherapy. However, few studies investigated the prognostic role of leptomeningeal metastases (LM) following whole brain radiotherapy (WBRT...

journal_title：Asia-Pacific journal of clinical oncology

authors： Sakaguchi M,Maebayashi T,Aizawa T,Ishibashi N,Saito T

更新日期：2017-10-01 00:00:00

abstract：PURPOSE:To study trends of urological cancers mortalities in Iran between 1990 and 2015 as a part of a larger project named national and subnational burden of diseases, injuries, and risk factors. METHODS:The primary dataset of this project comprises data of national death registration system. Cause-specific mortality...

journal_title：Asia-Pacific journal of clinical oncology

authors： Pishgar F,Amini E,Gohari K,Aminorroaya A,Sheidaei A,Rostamabadi Y,Ebrahimi H,Yoosefi M,Naderimagham S,Rezaei N,Modirian M,Namazi Shabestari A,Kompani F,Farzadfar F

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Azacitidine safety and efficacy were established in studies of mainly Caucasian patients. Differences in drug metabolism enzymes between Caucasian and East Asian populations prevent extrapolation of drug effects between these groups. This phase 2 study evaluated azacitidine safety, efficacy and pharmacokinet...

journal_title：Asia-Pacific journal of clinical oncology

authors： Du X,Lai YY,Xiao Z,Liu T,Hu Y,Sun A,Li X,Shen ZX,Jin J,Yu L,Laille E,Dong Q,Songer S,Beach CL

更新日期：2018-06-01 00:00:00

abstract：AIM:Carboplatin dosing depends on accurate glomerular filtration rate (GFR) estimation. There is a lack of clinical agreement about carboplatin dosing when the GFR measurement is very high (>110 mL/min). METHODS:A retrospective audit of pre-chemotherapy 99m technetium (Tc) diethylenetriamene pentaacetate (DTPA) radion...

journal_title：Asia-Pacific journal of clinical oncology

authors： Roy AC,Jones DN,Slavotinek JP,Kichenadasse G,Karapetis C,Lam E,Bishnoi S,Koczwara B

更新日期：2011-09-01 00:00:00

abstract：AIMS:Quality of life (QOL) is important in patients with advanced cancer. The European Organisation for Research and Treatment of Cancer (EORTC) QLQ-C30 is a general QOL tool used in cancer patients. Often, with a large enough sample, statistical significance of changecan be reached, however the clinical significance i...

journal_title：Asia-Pacific journal of clinical oncology

authors： Bedard G,Zeng L,Zhang L,Lauzon N,Holden L,Tsao M,Danjoux C,Barnes E,Sahgal A,Poon M,Chow E

更新日期：2014-06-01 00:00:00

abstract：:First-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are used as first-line therapy in patients with non-small cell lung cancer (NSCLC) harboring a sensitizing mutation in the EGFR gene. Unfortunately, resistance to these therapies often occurs within 10 months of commencing treat...

journal_title：Asia-Pacific journal of clinical oncology

authors： John T,Bowden JJ,Clarke S,Fox SB,Garrett K,Horwood K,Karapetis CS

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Clinical trials investigating the effects of addition of oxaliplatin to neoadjuvant radiochemotherapy in locally advanced rectal cancers (LARCs) have brought controversial results for pathologic complete response as an endpoint. This randomized clinical trial investigated downstaging as a short-term surrogat...

journal_title：Asia-Pacific journal of clinical oncology

authors： Haddad P,Miraie M,Farhan F,Fazeli MS,Alikhassi A,Maddah-Safaei A,Aghili M,Kalaghchi B,Babaei M

更新日期：2017-12-01 00:00:00

abstract：AIM:While first-line palliative chemotherapy (CT1) improves survival and quality of life in advanced biliary cancer (ABC), there is no randomized evidence to support second-line chemotherapy (CT2) in ABC. We aim to explore to role of CT2 in ABC. METHODS:We performed a retrospective review of all patients who received ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Brungs D,Aghmesheh M,Sjoquist K,Goldstein D

更新日期：2017-10-01 00:00:00

abstract：AIMS:In this study, we intended to analyze the clinical significance of CD4+ FoxP3+ Tregs in gastric cancer patients and investigate the relationship between the proportion of CD4+ FoxP3+ Tregs in the peripheral blood and the expression of FoxM1 and Ki-67 in gastric cancer tissues. METHODS:Flow cytometry was used to m...

journal_title：Asia-Pacific journal of clinical oncology

authors： Ma K,Li X,Lv J,Liu Z,Zhang L,Cong H,Wang H,Shen F,Yue L

更新日期：2020-01-19 00:00:00

abstract：AIM:Long noncoding RNAs play a key role in the development and progression of various human cancers. Recently, LINC00852 has been reported to be associated with spinal metastasis lung adenocarcinoma. However, the role and potential mechanisms of LINC00852 in prostate cancer cells remain largely unknown. METHODS:LINC00...

journal_title：Asia-Pacific journal of clinical oncology

authors： Yi S,Li G,Sun B

更新日期：2020-10-30 00:00:00

abstract：AIM:Colorectal cancer (CRC) is one of the most common malignancies worldwide and adjuvant chemotherapy is proven to improve survival in patients with Dukes' C CRC. The purpose of this study was to analyze factors influencing referral to medical oncology in patients with Dukes' C colonic cancer in our institutions. MET...

journal_title：Asia-Pacific journal of clinical oncology

authors： Lu CT,Stephens JH,Rieger NA

更新日期：2010-09-01 00:00:00

abstract：AIM:Cabazitaxel is a next generation taxane that has been shown to improve overall survival in patients with metastatic castration-resistant prostate cancer (mCRPC) whose disease progressed during or after docetaxel-based therapy. A worldwide early access program (EAP) study was established to provide access to cabazit...

journal_title：Asia-Pacific journal of clinical oncology

authors： Parente P,Ng S,Parnis F,Guminski A,Gurney H

更新日期：2017-12-01 00:00:00

abstract：AIM:Selective internal radiation therapy with yttrium-90 microsphere radioembolization has been used to treat unresectable liver tumors and its acute toxicity has been well described. Subacute and long-term hepatic complications related to radioembolization however may be underreported in the literature. This retrospec...

journal_title：Asia-Pacific journal of clinical oncology

authors： Kuo JC,Tazbirkova A,Allen R,Kosmider S,Gibbs P,Yip D

更新日期：2014-09-01 00:00:00

abstract：AIM:Survival rates for patients with cancer who live in rural and regional areas are worse than in metropolitan areas. This may be due to geographical isolation, delayed diagnosis, inadequate transport, lower socioeconomic status and workforce shortages. We conducted a qualitative study of rural patients, carers and he...

journal_title：Asia-Pacific journal of clinical oncology

authors： Grimison P,Phillips F,Butow P,White K,Yip D,Sardelic F,Underhill C,Tse R,Simes R,Turley K,Raymond C,Goldstein D

更新日期：2013-09-01 00:00:00