Additional chemotherapy and salvage surgery for poor response to chemoradiotherapy in rectal cancers.

abstract：AIMS:Esophageal cancer (EC) is one of the most prevalent and deadly cancers worldwide. Along with nutrition, smoking and alcohol consumption, human papillomavirus (HPV) infection is one of the major risk factors, which is modulated by host immune response. This study is aimed at elucidating how HPV modifies host immune...

journal_title：Asia-Pacific journal of clinical oncology

authors： Feng B,Awuti I,Deng Y,Li D,Niyazi M,Aniwar J,Sheyhidin I,Lu G,Li G,Zhang L

更新日期：2014-03-01 00:00:00

abstract：AIM:The ACCElox registry was set up to assess therapeutic management of early-stage colon cancer with oxaliplatin/5-fluorouracil (5-FU)-based regimen and the duration of adjuvant chemotherapy in current clinical practice. METHODS:This prospective observational study was conducted between 2006 and 2008 in 19 countries ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Park YS,Ji J,Zalcberg JR,El-Serafi M,Buzaid A,Ghosn M

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Acral melanoma (AM) and mucosal melanoma (MM) make up more than half of melanomas in Asia but comprise only 5% of cases in Caucasians, where cutaneous melanoma (CM) predominates. AM and MM are thought to be genetically and biologically distinct from CM. We report the characteristics and outcomes of melanoma ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Teh YL,Goh WL,Tan SH,Yong G,Sairi ANH,Soo KC,Ong J,Chia C,Tan G,Soeharno H,Tan MH,Chan M,Sathiyamoorthy S,Sittampalam K,Teh J,Chin F,Sethi V,Teo M,Quek R,Farid M

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:An elevated preoperative aspartate aminotransferase-to-lymphocyte ratio index (ALRI) may predict poor survival in various cancers. However, the prognostic value of aminotransferase-to-lymphocyte ratio index (ALRI) in patients with hepatocellular carcinoma (HCC) remains to be determined. MATERIALS AND METHOD...

journal_title：Asia-Pacific journal of clinical oncology

authors： Chen Y,He C,Wen T,Yan L,Yang J

更新日期：2020-10-30 00:00:00

abstract：:Cancer in pregnancy may be increasing in incidence with advancing maternal age and higher rates of obesity. The diagnosis of cancer in pregnancy provokes complex management issues balancing short- and long-term risks for both mother and baby. Every case needs to be individualized, with a multidisciplinary team of midw...

journal_title：Asia-Pacific journal of clinical oncology

authors： Eastwood-Wilshere N,Turner J,Oliveira N,Morton A

更新日期：2019-12-01 00:00:00

abstract：:The rationale for certain patterns of metastatic spread seen in melanoma is not well understood. Currently, there is no clear experimental evidence to support the potential for metastases to form metastases in this disease. We report a case of a 31-year-old woman, with metastatic melanoma, who developed axillary lymph...

journal_title：Asia-Pacific journal of clinical oncology

authors： Bowyer S,Feeney K,Millward M

更新日期：2014-12-01 00:00:00

abstract：:Carboplatin is a platinum analogue, widely used in the treatment of numerous cancer types including lung, genitourinary and ovarian cancers. It is also used in the adjuvant treatment of human epidermal growth factor receptor 2 positive breast cancer, where a non-anthracycline regimen is preferred. It is considered gen...

journal_title：Asia-Pacific journal of clinical oncology

authors： Turner N,Stewart J,Barnett F,White S

更新日期：2012-09-01 00:00:00

abstract：:Ipilimumab is a human anti-CTLA-4 monoclonal antibody recently approved for the treatment of advanced melanoma. Stimulation of T-cell activity unmasks antitumor activity, but can cause immune-related adverse events. Autoimmune hypophysitis is of particular importance because its presentation can be subtle but life thr...

journal_title：Asia-Pacific journal of clinical oncology

authors： Tiu C,Pezaro C,Davis ID,Grossmann M,Parente P

更新日期：2015-06-01 00:00:00

abstract：AIM:Complementary medicine (CAM) use in the cancer population is higher than the general population: some studies estimate up to 70%. Our Medicines Information Centre, in a tertiary cancer institution, receives many enquiries regarding use and safety of CAM with conventional cancer therapies (chemotherapy, radiotherapy...

journal_title：Asia-Pacific journal of clinical oncology

authors： Brooks SL,Rowan G,Michael M

更新日期：2018-10-01 00:00:00

abstract：:The precise cell types that give rise to tumors and mechanisms that underpin tumor heterogeneity are poorly understood. There is increasing evidence to suggest that diverse solid tumors are hierarchically organized and may be sustained by a distinct subpopulation of cancer stem cells (CSCs). The CSC hypothesis provide...

journal_title：Asia-Pacific journal of clinical oncology

authors： Lindeman GJ,Visvader JE

更新日期：2010-06-01 00:00:00

abstract：AIM:The effects of image-guided radiotherapy (IGRT, an advanced RT technology) have been debated in the literature. We compared the outcomes of locally advanced rectal cancer (LARC) patients treated with neoadjuvant concurrent chemoradiotherapy (NCCRT; with vs without IGRT) in a large population-based propensity score ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Li CC,Liang JA,Chen WT,Chien CR

更新日期：2019-10-01 00:00:00

abstract：:An improved understanding of the important role of angiogenesis in tumor biology has led to development of different antiangiogenic therapies. Numerous clinical studies for several antiangiogenic agents have recently been conducted in breast cancer patients and have shown clinically significant improvement in outcomes...

journal_title：Asia-Pacific journal of clinical oncology

authors： Wu Y,Sun WL,Feng JF

更新日期：2013-06-01 00:00:00

abstract：AIM:Survival rates for patients with cancer who live in rural and regional areas are worse than in metropolitan areas. This may be due to geographical isolation, delayed diagnosis, inadequate transport, lower socioeconomic status and workforce shortages. We conducted a qualitative study of rural patients, carers and he...

journal_title：Asia-Pacific journal of clinical oncology

authors： Grimison P,Phillips F,Butow P,White K,Yip D,Sardelic F,Underhill C,Tse R,Simes R,Turley K,Raymond C,Goldstein D

更新日期：2013-09-01 00:00:00

abstract：:First-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are used as first-line therapy in patients with non-small cell lung cancer (NSCLC) harboring a sensitizing mutation in the EGFR gene. Unfortunately, resistance to these therapies often occurs within 10 months of commencing treat...

journal_title：Asia-Pacific journal of clinical oncology

authors： John T,Bowden JJ,Clarke S,Fox SB,Garrett K,Horwood K,Karapetis CS

更新日期：2017-08-01 00:00:00

abstract：AIMS:Wilms tumor (WT) is rare in Asia. Treatment of bilateral WT is challenging, and the treatment outcome of bilateral WT is rarely reported in low incidence areas. METHODS:We enrolled patients with bilateral WT registered in Chang Gung Memorial Hospital, Taoyuan, Taiwan, between January 1986 and June 2015. They were...

journal_title：Asia-Pacific journal of clinical oncology

authors： Chen SH,Hung IJ,Yang CP,Jaing TH,Wang CJ,Hsueh C,Lai JY

更新日期：2016-09-01 00:00:00

abstract：:The association between the rs498872 single nucleotide polymorphism (SNP) and glioma risk has been studied, but these studies have yielded conflicting results. In order to explore this association, we performed a meta-analysis. A comprehensive literature search was performed using PubMed and EMBASE database, with the ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Gao X,Mi Y,Yan A,Sha B,Guo N,Hu Z,Zhang N,Jiang F,Gou X

更新日期：2015-12-01 00:00:00

abstract：:Cancer, its therapy, and related adverse effects have been associated with reduced work performance, including absenteeism (i.e. absence from scheduled work due to health problems) and presenteeism (i.e. impaired on-the-job performance due to health problems) among cancer survivors. This review aimed to compare the wo...

journal_title：Asia-Pacific journal of clinical oncology

authors： Soejima T,Kamibeppu K

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Azacitidine safety and efficacy were established in studies of mainly Caucasian patients. Differences in drug metabolism enzymes between Caucasian and East Asian populations prevent extrapolation of drug effects between these groups. This phase 2 study evaluated azacitidine safety, efficacy and pharmacokinet...

journal_title：Asia-Pacific journal of clinical oncology

authors： Du X,Lai YY,Xiao Z,Liu T,Hu Y,Sun A,Li X,Shen ZX,Jin J,Yu L,Laille E,Dong Q,Songer S,Beach CL

更新日期：2018-06-01 00:00:00

abstract：AIM:The open-label, nonrandomized, phase II APEC study enrolled 167 patients with RAS wild-type (wt) metastatic colorectal cancer (mCRC) to investigate the safety and efficacy of first-line, every-2-weeks cetuximab plus investigator's choice of FOLFIRI or FOLFOX in this patient population. METHODS:A subgroup analysis ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Price T,Shen L,Ma B,Esser R,Chen W,Gibbs P,Lim R,Cheng AL

更新日期：2019-08-01 00:00:00

abstract：AIM:The purpose of this study was to investigate the impact of subcarinal dissection on short-term outcome and survival following esophagectomy in patients with thoracic esophageal squamous cell carcinoma. METHODS:A total of 2252 patients underwent an esophagectomy for esophageal cancer from January 1997 to December 2...

journal_title：Asia-Pacific journal of clinical oncology

authors： Hu W,Liang Y,Zhang S,Hu Y,Liu J

更新日期：2014-06-01 00:00:00

abstract：AIM:To describe the development of the content and pilot testing of a radiation therapist-led educational intervention for breast cancer patients about to commence radiotherapy. Pilot testing consisted of testing the intervention for appropriateness, feasibility and acceptance. METHODS:A tailored intervention consisti...

journal_title：Asia-Pacific journal of clinical oncology

authors： Halkett GK,Schofield P,O'Connor M,York D,Jefford M,Jiwa M,Spry N,Taylor M,Aranda S

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Providing appropriate educational resources to patients with head and neck cancer (HNC) is important but challenging. The aim of this study was to determine Australian clinicians' perceptions of currently used HNC information resources. METHODS:A purpose-designed questionnaire was disseminated electronicall...

journal_title：Asia-Pacific journal of clinical oncology

authors： Jabbour J,Wykes J,Milross C,Sundaresan P,Ebrahimi A,Shepherd HL,Dhillon HM,Clark JR

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:Clinical trials investigating the effects of addition of oxaliplatin to neoadjuvant radiochemotherapy in locally advanced rectal cancers (LARCs) have brought controversial results for pathologic complete response as an endpoint. This randomized clinical trial investigated downstaging as a short-term surrogat...

journal_title：Asia-Pacific journal of clinical oncology

authors： Haddad P,Miraie M,Farhan F,Fazeli MS,Alikhassi A,Maddah-Safaei A,Aghili M,Kalaghchi B,Babaei M

更新日期：2017-12-01 00:00:00

abstract：AIM:To describe the overall survival, progression-free survival, response rate and toxicity of pegylated liposomal doxorubicin (PLD) in recurrent ovarian cancer. METHODS:A retrospective study of 45 patients with recurrent or progressive ovarian cancer was conducted at the Westmead Cancer Care Centre. Patients received...

journal_title：Asia-Pacific journal of clinical oncology

authors： Dear RF,Gao B,Harnett P

更新日期：2010-03-01 00:00:00

abstract：AIM:To carry out a nationwide study of KRAS testing in metastatic colorectal cancer as reported by nine major molecular pathology service providers in Australia, including mutation frequencies and turnaround times that might impact on patient care. METHODS:Participating laboratories contributed information on KRAS mut...

journal_title：Asia-Pacific journal of clinical oncology

authors： Scott RJ,Fox SB,Desai J,Grieu F,Amanuel B,Garrett K,Harraway J,Cheetham G,Pattle N,Haddad A,Byron K,Rudzki B,Waring P,Iacopetta B

更新日期：2014-09-01 00:00:00

abstract：AIM:Cabazitaxel is a next generation taxane that has been shown to improve overall survival in patients with metastatic castration-resistant prostate cancer (mCRPC) whose disease progressed during or after docetaxel-based therapy. A worldwide early access program (EAP) study was established to provide access to cabazit...

journal_title：Asia-Pacific journal of clinical oncology

authors： Parente P,Ng S,Parnis F,Guminski A,Gurney H

更新日期：2017-12-01 00:00:00

abstract：AIM:Clinical and pharmacokinetic effects of azacitidine in higher-risk myelodysplastic syndromes were established in mainly Caucasian populations. Because of inter-ethnic genotype variability of drug-metabolizing enzymes, it is important to evaluate azacitidine in populations expected to use the drug. METHODS:In this ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Chou WC,Yeh SP,Hsiao LT,Lin SF,Chen YC,Chen TY,Laille E,Galettis A,Dong Q,Songer S,Beach CL

更新日期：2017-10-01 00:00:00

abstract：AIM:To evaluate predictive factors which associated with oncological outcomes to first-line axitinib for metastatic renal cell carcinoma (mRCC). METHODS:A retrospective chart review was conducted patients who had been treated with axitinib as first-line therapy for the treatment of mRCC from September 2013 to February...

journal_title：Asia-Pacific journal of clinical oncology

authors： Kameda T,Takayama T,Sugihara T,Takeshima S,Yamazaki M,Komatsubara M,Kamei J,Fujisaki A,Ando S,Kurokawa S,Fujimura T

更新日期：2020-08-01 00:00:00

abstract：AIM:Metadherin (MTDH) is a potential oncogene in tumor development and is highly expressed in various types of human cancers. However, there has been no report on the role of MTDH in bladder cancer. Our aim was to investigate the expression pattern of MTDH in bladder tissue at different clinic pathological stages and e...

journal_title：Asia-Pacific journal of clinical oncology

authors： Zhou J,Li J,Wang Z,Yin C,Zhang W

更新日期：2012-09-01 00:00:00

abstract：AIM:Mucositis is a major complication of irradiation in head and neck tumors, the addition of chemotherapy to irradiation may enhance this dose-limiting problem. Licorice is a strong demulcent that had been effectively used in treatment of peptic ulcer. The main purpose of this study was to compare the therapeutic safe...

journal_title：Asia-Pacific journal of clinical oncology

authors： Ghalayani P,Emami H,Pakravan F,Nasr Isfahani M

更新日期：2017-04-01 00:00:00