Cancer in Pregnancy.

abstract：:Non-small cell lung cancers (NSCLC) harboring the uncommon epidermal growth factor receptor (EGFR) exon 20 insertion mutations are generally thought to be unresponsive to EGFR-tyrosine kinase inhibitor (TKI) therapy. Presented here is a case of stage IV NSCLC harboring an uncommon EGFR exon 20 insertion mutation that ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Chan RT

更新日期：2018-03-01 00:00:00

abstract：AIM:The effect of transcatheter arterial chemoembolization (TACE) therapy on hepatitis B virus (HBV) reactivation in hepatocellular carcinoma (HCC) patients with prior resolved hepatitis B is not fully understood. METHODS:From January 2006 to December 2010, 43 hepatitis B surface antigen (HBsAg)-negative/anti-hepatiti...

journal_title：Asia-Pacific journal of clinical oncology

authors： Peng JW,Lin GN,Xiao JJ,Jiang XM

更新日期：2012-12-01 00:00:00

abstract：AIM:While first-line palliative chemotherapy (CT1) improves survival and quality of life in advanced biliary cancer (ABC), there is no randomized evidence to support second-line chemotherapy (CT2) in ABC. We aim to explore to role of CT2 in ABC. METHODS:We performed a retrospective review of all patients who received ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Brungs D,Aghmesheh M,Sjoquist K,Goldstein D

更新日期：2017-10-01 00:00:00

abstract：AIM:Clinical and pharmacokinetic effects of azacitidine in higher-risk myelodysplastic syndromes were established in mainly Caucasian populations. Because of inter-ethnic genotype variability of drug-metabolizing enzymes, it is important to evaluate azacitidine in populations expected to use the drug. METHODS:In this ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Chou WC,Yeh SP,Hsiao LT,Lin SF,Chen YC,Chen TY,Laille E,Galettis A,Dong Q,Songer S,Beach CL

更新日期：2017-10-01 00:00:00

abstract：AIM:To validate and compare the Chinese version of the European Organization for Research and Treatment of Cancer Quality of Life-Chemotherapy-Induced Peripheral Neuropathy Questionnaire (EORTC QLQ-CIPN20) and the Functional Assessment of Cancer-Gynecologic Oncology Group-Neurotoxicity subscale (FACT/GOG-Ntx) for measu...

journal_title：Asia-Pacific journal of clinical oncology

authors： Cheng HL,Molassiotis A

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Acral melanoma (AM) and mucosal melanoma (MM) make up more than half of melanomas in Asia but comprise only 5% of cases in Caucasians, where cutaneous melanoma (CM) predominates. AM and MM are thought to be genetically and biologically distinct from CM. We report the characteristics and outcomes of melanoma ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Teh YL,Goh WL,Tan SH,Yong G,Sairi ANH,Soo KC,Ong J,Chia C,Tan G,Soeharno H,Tan MH,Chan M,Sathiyamoorthy S,Sittampalam K,Teh J,Chin F,Sethi V,Teo M,Quek R,Farid M

更新日期：2018-04-01 00:00:00

abstract：AIM:A viable and sustainable medical oncology profession is integral for meeting the increasing demand for quality cancer care. The aim of this study was to explore the workforce-related experiences, perceptions and career expectations of early-career medical oncologists in Australia. METHODS:A mixed-methods design, i...

journal_title：Asia-Pacific journal of clinical oncology

authors： Wong WKT,Kirby E,Broom A,Sibbritt D,Francis K,Karapetis CS,Karikios D,Harrup R,Lwin Z

更新日期：2018-10-01 00:00:00

abstract：AIMS:The optimal maintenance therapy for patients with acute promyelocytic leukemia (APL) who achieved complete remission (CR) and complete consolidation chemotherapy is still controversial. Whether the use of arsenic trioxide (ATO) alone or along with all-trans retinoic acid (ATRA) improves overall survival (OS) or di...

journal_title：Asia-Pacific journal of clinical oncology

authors： Chiang YH,Chang YF,Hsieh RK,Lin J,Chen CG,Lim KH,Lin HC,Chang MC

更新日期：2012-12-01 00:00:00

abstract：AIM:A proportion of locally advanced rectal cancer patients who receive neoadjuvant chemoradiotherapy (NACRT) are still unresectable. This study was undertaken to assess the outcomes of giving additional chemotherapy to rectal cancer patients with unresectable disease after NACRT. METHODS:Patients with poor response t...

journal_title：Asia-Pacific journal of clinical oncology

authors： Engineer R,Ostwal V,Arya S,Gupta P,Chopra S,Patil P,Jatal S,Saklani A

更新日期：2017-08-01 00:00:00

abstract：:The COVID-19 pandemic will present a range of challenges to radiation oncology departments. Early data suggest that cancer patients carry a higher than average, but still low absolute risk of hospitalization from COVID-19. The risk of severe events for those who are hospitalized however, is high. Resources for usual c...

journal_title：Asia-Pacific journal of clinical oncology

authors： Horsley PJ,Back M,Lamoury G,Porter B,Booth J,Eade TN

更新日期：2021-02-01 00:00:00

abstract：:Resistance to endocrine therapy is a significant therapeutic challenge in the treatment of women with hormone receptor positive (HR+), human epidermal growth factor receptor 2 negative (HER2-) advanced breast cancer. Cyclin-dependent kinase (CDK)4/6 inhibitors in combination with endocrine therapy have been shown to i...

journal_title：Asia-Pacific journal of clinical oncology

authors： Boyle F,Beith J,Burslem K,de Boer R,Hui R,Lim E,McCarthy N,Redfern A,Woodward N

更新日期：2018-10-01 00:00:00

abstract：:It is important to distinguish between tumor recurrence and treatment effects in posttreatment patients with high-grade gliomas. Several imaging modalities have been reported in differentiating between tumor recurrence and treatment effects. However, there were no consistent conclusions between different studies. We p...

journal_title：Asia-Pacific journal of clinical oncology

authors： Wang X,Hu X,Xie P,Li W,Li X,Ma L

更新日期：2015-06-01 00:00:00

abstract：:The association between the rs498872 single nucleotide polymorphism (SNP) and glioma risk has been studied, but these studies have yielded conflicting results. In order to explore this association, we performed a meta-analysis. A comprehensive literature search was performed using PubMed and EMBASE database, with the ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Gao X,Mi Y,Yan A,Sha B,Guo N,Hu Z,Zhang N,Jiang F,Gou X

更新日期：2015-12-01 00:00:00

abstract：AIM:Colorectal cancer (CRC) is one of the most common malignancies worldwide and adjuvant chemotherapy is proven to improve survival in patients with Dukes' C CRC. The purpose of this study was to analyze factors influencing referral to medical oncology in patients with Dukes' C colonic cancer in our institutions. MET...

journal_title：Asia-Pacific journal of clinical oncology

authors： Lu CT,Stephens JH,Rieger NA

更新日期：2010-09-01 00:00:00

abstract：AIM:Multidisciplinary care is advocated as best practice in cancer care. Relatively little is documented about multidisciplinary team (MDT) meeting functioning, decision making and the use of evidence to support decision making in Australia. This descriptive study aimed to examine team functioning, the role of team mee...

journal_title：Asia-Pacific journal of clinical oncology

authors： Rankin NM,Lai M,Miller D,Beale P,Spigelman A,Prest G,Turley K,Simes J

更新日期：2018-02-01 00:00:00

abstract：AIM:We investigated prognostic significance of methylation status of MASPIN gene and its protein expression in normal subjects, cholelithiasis and gallbladder cancer (GBC) patients. METHODS:MASPIN protein expression and its promoter methylation in gallbladder tissue of cholelithiasis (n = 36), GBC (n = 46) and control...

journal_title：Asia-Pacific journal of clinical oncology

authors： Baghel K,Kazmi HR,Chandra A,Raj S,Srivastava RN

更新日期：2019-10-01 00:00:00

abstract：AIMS:Quality of life (QOL) is important in patients with advanced cancer. The European Organisation for Research and Treatment of Cancer (EORTC) QLQ-C30 is a general QOL tool used in cancer patients. Often, with a large enough sample, statistical significance of changecan be reached, however the clinical significance i...

journal_title：Asia-Pacific journal of clinical oncology

authors： Bedard G,Zeng L,Zhang L,Lauzon N,Holden L,Tsao M,Danjoux C,Barnes E,Sahgal A,Poon M,Chow E

更新日期：2014-06-01 00:00:00

abstract：AIM:To evaluate the distribution of the Oncotype DX Recurrence Score (a validated prognostic/predictive tool in early-stage estrogen-receptor positive [ER+] breast cancer) and its impact on adjuvant treatment decisions in the United Arab Emirates. METHODS:A retrospective analysis of a single-center cohort. RESULTS:Th...

journal_title：Asia-Pacific journal of clinical oncology

authors： Jaafar H,Bashir MA,Taher A,Qawasmeh K,Jaloudi M

更新日期：2014-12-01 00:00:00

abstract：:Carboplatin is a platinum analogue, widely used in the treatment of numerous cancer types including lung, genitourinary and ovarian cancers. It is also used in the adjuvant treatment of human epidermal growth factor receptor 2 positive breast cancer, where a non-anthracycline regimen is preferred. It is considered gen...

journal_title：Asia-Pacific journal of clinical oncology

authors： Turner N,Stewart J,Barnett F,White S

更新日期：2012-09-01 00:00:00

abstract：AIM:To investigate the role of endothelial cell damage in radiation-induced lung injury. METHODS:A total of 60 male Sprague-Dawley rats were irradiated to the right hemithorax with a single dose of 0, 7.0 or 14.4 Gy. Serial studies were performed before and at 1, 7, 30 and 90 days after radiation, respectively. Pathol...

journal_title：Asia-Pacific journal of clinical oncology

authors： Qiu J,Li J,He TC

更新日期：2011-12-01 00:00:00

abstract：PURPOSE:Mitomycin C (MMC) plus standard 5-fluorouracil (FU) infusion in weeks 1 and 5 often contributes to radiotherapy interruptions and possibly less-than-ideal outcomes in anal cancer. This study was to evaluate alternative strategies for chemotherapy delivery that might be less toxic or more efficacious, and outcom...

journal_title：Asia-Pacific journal of clinical oncology

authors： Ngan D,Chu J,Chander S,Michael M,Heriot AG,Ngan SY,Rischin D,Leong T

更新日期：2019-02-01 00:00:00

abstract：AIM:This systematic review and meta-analysis was performed to assess the efficacy and side effects between single-agent and doublet chemotherapy in first-line treatment of advanced non-small cell lung cancer with performance status 2 (PS2). METHODS:We searched for randomized controlled trials in online electronic data...

journal_title：Asia-Pacific journal of clinical oncology

authors： Luo L,Hu Q,Jiang JX,Yang X,Dinglin XX,Lin X,Yao HR

更新日期：2015-09-01 00:00:00

abstract：AIM:A newly developed cervical cancer screening method - folate receptor-mediated epithelium staining utilizes methylene blue internalized by folate receptor-mediated endocytosis to stain cervical intra-epithelial neoplasia. We test the clinical feasibility of this method in this study. METHODS:A total of 14 344 women...

journal_title：Asia-Pacific journal of clinical oncology

authors： Li D,Chen L,Wang H,Yang H,Dai Y,Yu C,Dong Y

更新日期：2017-02-01 00:00:00

abstract：AIM:Behavioral interventions such as exercise may induce epigenetic changes. Only few studies investigated the effects of exercise on epigenetic alterations in colorectal cancer survivors. The aim of this study was to explore the changes of genome-wide DNA methylation after 6-week exercise training in colorectal cancer...

journal_title：Asia-Pacific journal of clinical oncology

authors： Hwang SH,Kang DW,Lee MK,Byeon JY,Park H,Park DH,Kim KC,Lee ST,Chu SH,Kim NK,Jeon JY

更新日期：2020-10-13 00:00:00

abstract：AIM:To investigate the association between plasma visfatin levels and risk of early and advanced colorectal cancer (CRC). METHODS:In total, 358 CRC patients and 286 controls were enrolled. According to the T factor of the TNM system. cancer patients were divided into two subgroups: early and advanced cancer. Levels of...

journal_title：Asia-Pacific journal of clinical oncology

authors： Chen M,Wang Y,Li Y,Zhao L,Ye S,Wang S,Yu C,Xie H

更新日期：2016-03-01 00:00:00

abstract：AIMS:Wilms tumor (WT) is rare in Asia. Treatment of bilateral WT is challenging, and the treatment outcome of bilateral WT is rarely reported in low incidence areas. METHODS:We enrolled patients with bilateral WT registered in Chang Gung Memorial Hospital, Taoyuan, Taiwan, between January 1986 and June 2015. They were...

journal_title：Asia-Pacific journal of clinical oncology

authors： Chen SH,Hung IJ,Yang CP,Jaing TH,Wang CJ,Hsueh C,Lai JY

更新日期：2016-09-01 00:00:00

abstract：AIM:Advanced esophagogastric carcinoma has a poor prognosis. Palliative chemotherapy provides a survival advantage and improved quality of life. Epirubicin, cisplatin and continuous infusional 5-fluorouracil (5-FU) (ECF) is a well-established chemotherapy regimen but a continuous chemotherapy infusion is not always fea...

journal_title：Asia-Pacific journal of clinical oncology

authors： Karapetis CS,Cheong KA,Yip D,Strickland AH,Steer C,Marx G,Yip S,Chrystal K,Harper PG

更新日期：2010-12-01 00:00:00

abstract：INTRODUCTION:The goal of this study was to determine the relationships among type 2 diabetes mellitus (DM), specific cancer histological types and mortality in hospitalized women. METHODS:Patients over 19 years of age were included if the indication for hospital admission was a diagnosis of type 2 DM or a malignancy. ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Chen JY,Chiou WK,Chou WY,Lin JD

更新日期：2016-03-01 00:00:00

abstract：AIM:Long noncoding RNAs play a key role in the development and progression of various human cancers. Recently, LINC00852 has been reported to be associated with spinal metastasis lung adenocarcinoma. However, the role and potential mechanisms of LINC00852 in prostate cancer cells remain largely unknown. METHODS:LINC00...

journal_title：Asia-Pacific journal of clinical oncology

authors： Yi S,Li G,Sun B

更新日期：2020-10-30 00:00:00

abstract：AIM:To describe the development of the content and pilot testing of a radiation therapist-led educational intervention for breast cancer patients about to commence radiotherapy. Pilot testing consisted of testing the intervention for appropriateness, feasibility and acceptance. METHODS:A tailored intervention consisti...

journal_title：Asia-Pacific journal of clinical oncology

authors： Halkett GK,Schofield P,O'Connor M,York D,Jefford M,Jiwa M,Spry N,Taylor M,Aranda S

更新日期：2012-09-01 00:00:00