Hormone receptor positive, HER2 negative metastatic breast cancer: Impact of CDK4/6 inhibitors on the current treatment paradigm.

abstract：AIM:Data on lung cancer survival are lacking in developing countries. Our objectives were to describe the survival of our lung cancer patients and to determine independent prognostic factors affecting survival. METHOD:All patients diagnosed with lung cancer from August 2007 to August 2010 were recruited from a single ...

journal_title：Asia-Pacific journal of clinical oncology

authors： How SH,Ng TH,Kuan YC,Jamalludin AR,Fauzi AR

更新日期：2015-09-01 00:00:00

abstract：AIMS:Cyclophosphamide was widely used as a single agent prior to the advent of platinum-based regimens for epithelial ovarian cancer, and, in combination with platinum, prior to the adoption of platinum and paclitaxel as standard first-line therapy. As cyclophosphamide currently has no defined role in ovarian cancer we...

journal_title：Asia-Pacific journal of clinical oncology

authors： Handolias D,Quinn M,Foo S,Mileshkin L,Grant P,Dutu G,Rischin D

更新日期：2016-03-01 00:00:00

abstract：AIMS:Extracorporeal irradiation and re-implantation (ECI) has been used as limb salvage surgery for musculoskeletal oncology patients. Biological reconstruction, no risk of disease transmission and immunological reaction, ready availability and preservation of bone stock are the major advantage of this surgical techniq...

journal_title：Asia-Pacific journal of clinical oncology

authors： Arpornchayanon O,Leerapun T,Pruksakorn D,Panichkul P

更新日期：2013-09-01 00:00:00

abstract：:Posterior reversible encephalopathy syndrome (PRES) is a neuro-radiological syndrome characterized by seizures, altered level of consciousness and visual disturbance. PRES is associated with hyperintense lesions on magnetic resonance imaging (MRI) most commonly seen in the posterior regions. In most cases symptoms and...

journal_title：Asia-Pacific journal of clinical oncology

authors： Femia G,Hardy TA,Spies JM,Horvath LG

更新日期：2012-06-01 00:00:00

abstract：AIMS:To evaluate the response and progression-free survival (PFS) of Malaysian patients with advanced lung adenocarcinoma and unknown epidermal growth factor receptor (EGFR) mutation status treated with gefitinib. METHODS:A retrospective analysis of consecutive patients with EGFR mutation unknown stage III or IV lung ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Liam CK,Ruthranesan M,Lee CH,Pang YK,Chua KT,Lim BK

更新日期：2012-09-01 00:00:00

abstract：AIM:The aim of this study was to explore the dynamics within second medical opinion consultations in patients with cancer. METHODS:Semi-structured interviews were held with four oncologists and were subjected to a thematic analysis to define the broad issues. These formed the basis of a survey distributed to Australia...

journal_title：Asia-Pacific journal of clinical oncology

authors： Philip J,Gold M,Schwarz M,Komesaroff P

更新日期：2011-03-01 00:00:00

abstract：AIM:The effects of image-guided radiotherapy (IGRT, an advanced RT technology) have been debated in the literature. We compared the outcomes of locally advanced rectal cancer (LARC) patients treated with neoadjuvant concurrent chemoradiotherapy (NCCRT; with vs without IGRT) in a large population-based propensity score ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Li CC,Liang JA,Chen WT,Chien CR

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Anti-HER2 therapy-related cardiotoxicity is well described in the context of clinical trials, particularly in the setting of early stage disease, but there is more limited data in advanced breast cancer and in the real world setting. MATERIAL AND METHODS:A prospectively-maintained registry database with 312...

journal_title：Asia-Pacific journal of clinical oncology

authors： Conduit C,de Boer RH,Lok S,Gibbs P,Malik L,Loh Z,Yeo B,Greenberg S,Devitt B,Lombard J,Nottage M,Collins I,Torres J,Nolan M,Nott L

更新日期：2020-12-01 00:00:00

abstract：AIM:To assess the prognostic significance of enhancement rate (ER) measured by contrast-enhanced ultrasonography (CEUS) in patients with hepatocellular carcinoma (HCC) undergoing radiofrequency ablation (RFA). MATERIALS AND METHODS:A total of 253 patients with single primary HCC undergoing preoperative CEUS and RFA we...

journal_title：Asia-Pacific journal of clinical oncology

authors： Zhou G,Cai ZQ,Luo J,Hu ZX,Luo H,Wu H,Chen Q

更新日期：2019-08-01 00:00:00

abstract：AIM:Integration of clinical genetics into oncology is variable. Sarcomas have a strong genetic component, with up to 1/30 patients carrying germline TP53 mutations. This study aimed to define genetic risk awareness among sarcoma physicians. Outcomes were attitudes toward genetic testing, level of cancer risk and awaren...

journal_title：Asia-Pacific journal of clinical oncology

authors： McBride KA,Schlub TE,Ballinger ML,Thomas DM,Tattersall MH

更新日期：2016-06-01 00:00:00

abstract：AIMS:Currently, the only standard systemic treatment for advanced hepatocellular carcinoma is sorafenib monotherapy. The study was conducted to assess the efficacy and safety of the novel combination of sorafenib and gemcitabine in the treatment of advanced hepatocellular carcinoma. METHODS:Between March 2008 and Octo...

journal_title：Asia-Pacific journal of clinical oncology

authors： Srimuninnimit V,Sriuranpong V,Suwanvecho S

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Small cell lung cancer is a rapidly progressive disease with high fatality. No sensitive and specific biomarker to assist in managing this disease exists currently. AIM:Role of pretreatment serum lactate dehydrogenase as a biomarker in small cell lung cancer. METHODS:A hospital-based cancer registry was us...

journal_title：Asia-Pacific journal of clinical oncology

authors： Hsieh AH,Tahkar H,Koczwara B,Kichenadasse G,Beckmann K,Karapetis C,Sukumaran S

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Definitive chemoradiotherapy (CRT) is the standard treatment for locally advanced head and neck cancer (HNC). However, for very elderly patients, the comparison of benefit/risk between definitive radiotherapy (RT) with and without systemic chemotherapy was equivocal. PATIENTS AND METHODS:The study was a sin...

journal_title：Asia-Pacific journal of clinical oncology

authors： Lai KM,Lin JT,Lu HJ,Liang CC,Chen MK

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Common diseases with potential to increase the risk of death from lung cancer have so far not been studied in large populations. METHODS:We did a population-based retrospective cohort study using nationwide health insurance claims data from 2005 to 2012 in Korea including 205 403 lung cancer patients. Multi...

journal_title：Asia-Pacific journal of clinical oncology

authors： Hong S,Park EC,Kim TH,Kwon JA,Yoo KB,Han KT,Yoo JW,Kim SJ

更新日期：2018-04-01 00:00:00

abstract：AIM:To carry out a nationwide study of KRAS testing in metastatic colorectal cancer as reported by nine major molecular pathology service providers in Australia, including mutation frequencies and turnaround times that might impact on patient care. METHODS:Participating laboratories contributed information on KRAS mut...

journal_title：Asia-Pacific journal of clinical oncology

authors： Scott RJ,Fox SB,Desai J,Grieu F,Amanuel B,Garrett K,Harraway J,Cheetham G,Pattle N,Haddad A,Byron K,Rudzki B,Waring P,Iacopetta B

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Providing appropriate educational resources to patients with head and neck cancer (HNC) is important but challenging. The aim of this study was to determine Australian clinicians' perceptions of currently used HNC information resources. METHODS:A purpose-designed questionnaire was disseminated electronicall...

journal_title：Asia-Pacific journal of clinical oncology

authors： Jabbour J,Wykes J,Milross C,Sundaresan P,Ebrahimi A,Shepherd HL,Dhillon HM,Clark JR

更新日期：2018-10-01 00:00:00

abstract：:Cancer in pregnancy may be increasing in incidence with advancing maternal age and higher rates of obesity. The diagnosis of cancer in pregnancy provokes complex management issues balancing short- and long-term risks for both mother and baby. Every case needs to be individualized, with a multidisciplinary team of midw...

journal_title：Asia-Pacific journal of clinical oncology

authors： Eastwood-Wilshere N,Turner J,Oliveira N,Morton A

更新日期：2019-12-01 00:00:00

abstract：AIMS:The optimal maintenance therapy for patients with acute promyelocytic leukemia (APL) who achieved complete remission (CR) and complete consolidation chemotherapy is still controversial. Whether the use of arsenic trioxide (ATO) alone or along with all-trans retinoic acid (ATRA) improves overall survival (OS) or di...

journal_title：Asia-Pacific journal of clinical oncology

authors： Chiang YH,Chang YF,Hsieh RK,Lin J,Chen CG,Lim KH,Lin HC,Chang MC

更新日期：2012-12-01 00:00:00

abstract：:Multidisciplinary oncology team meetings are crucial hubs for integrated, patient-centered diagnosis and treatment planning. Team meetings are designed to enact the best practice principles of multidisciplinary care. Yet surveys of clinicians and allied health providers who are members of multidisciplinary teams (MDTs...

journal_title：Asia-Pacific journal of clinical oncology

authors： Lamprell K,Arnolda G,Delaney GP,Liauw W,Braithwaite J

更新日期：2019-08-01 00:00:00

abstract：AIM:Colorectal cancer (CRC) is one of the most common malignancies worldwide and adjuvant chemotherapy is proven to improve survival in patients with Dukes' C CRC. The purpose of this study was to analyze factors influencing referral to medical oncology in patients with Dukes' C colonic cancer in our institutions. MET...

journal_title：Asia-Pacific journal of clinical oncology

authors： Lu CT,Stephens JH,Rieger NA

更新日期：2010-09-01 00:00:00

abstract：:First-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are used as first-line therapy in patients with non-small cell lung cancer (NSCLC) harboring a sensitizing mutation in the EGFR gene. Unfortunately, resistance to these therapies often occurs within 10 months of commencing treat...

journal_title：Asia-Pacific journal of clinical oncology

authors： John T,Bowden JJ,Clarke S,Fox SB,Garrett K,Horwood K,Karapetis CS

更新日期：2017-08-01 00:00:00

abstract：:For advanced and metastatic urothelial carcinomas (UCs), platinum (preferably cisplatin)-based chemotherapy has been the standard treatment for many years. However, many patients are ineligible for cisplatin-based chemotherapy because of poor performance status and/or other age-related conditions. At the other end of ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Poon DM

更新日期：2020-09-01 00:00:00

abstract：INTRODUCTION:Left- and right-sided colon cancers were significantly different in epidemiologic, clinical and histological parameters. However, the impact of primary tumor location in metastatic colon cancer treated with front-line targeted triplet regimens is unclear, particularly in Asian populations. METHODS:A total...

journal_title：Asia-Pacific journal of clinical oncology

authors： Lu HJ,Lin JK,Chen WS,Jiang JK,Yang SH,Lan YT,Lin CC,Chang SC,Teng HW

更新日期：2016-09-01 00:00:00

abstract：AIM:The purpose of this study was to investigate the impact of subcarinal dissection on short-term outcome and survival following esophagectomy in patients with thoracic esophageal squamous cell carcinoma. METHODS:A total of 2252 patients underwent an esophagectomy for esophageal cancer from January 1997 to December 2...

journal_title：Asia-Pacific journal of clinical oncology

authors： Hu W,Liang Y,Zhang S,Hu Y,Liu J

更新日期：2014-06-01 00:00:00

abstract：AIM:Multidisciplinary care is advocated as best practice in cancer care. Relatively little is documented about multidisciplinary team (MDT) meeting functioning, decision making and the use of evidence to support decision making in Australia. This descriptive study aimed to examine team functioning, the role of team mee...

journal_title：Asia-Pacific journal of clinical oncology

authors： Rankin NM,Lai M,Miller D,Beale P,Spigelman A,Prest G,Turley K,Simes J

更新日期：2018-02-01 00:00:00

abstract：AIM:Self-expandable metallic stents (SEMS) have been used for palliation in patients with malignant gastroduodenal obstructions. We evaluated clinical outcomes after SEMS placement and identified prognostic factors of SEMS patency, including chemotherapy. METHODS:A review of records of 85 patients with unresectable ga...

journal_title：Asia-Pacific journal of clinical oncology

authors： Cha BH,Lee SH,Kim JE,Yoo JY,Park YS,Kim JW,Jeong SH,Kim N,Lee DH,Hwang JH

更新日期：2013-06-01 00:00:00

abstract：AIM:To examine the treatment practices for cancer pain relief and adverse event management, and the factors related to patient outcomes in the participating countries/regions. METHODS:The study was a cross-sectional survey conducted between September and December 2013 in 10 countries/regions across Asia. Adult patient...

journal_title：Asia-Pacific journal of clinical oncology

authors： Ho KY,Ahn JS,Calimag MM,Chao TC,Kim YC,Moon H,Tho LM,Xia ZJ,You D

更新日期：2018-06-01 00:00:00

abstract：:We report a case of acute inflammatory demyelinating polyradiculoneuropathy (AIDP) that developed in a patient with cholangiocarcinoma after receiving oxaliplatin-based chemotherapy. A 62-year-old man had multiple hypodense lesions with delayed enhancement in the both lobes of the liver on abdominal computed tomograph...

journal_title：Asia-Pacific journal of clinical oncology

authors： Yoon JY,Nam TS,Kim MK,Hwang JE,Shim HJ,Cho SH,Chung IJ,Bae WK

更新日期：2012-06-01 00:00:00

abstract：:An improved understanding of the important role of angiogenesis in tumor biology has led to development of different antiangiogenic therapies. Numerous clinical studies for several antiangiogenic agents have recently been conducted in breast cancer patients and have shown clinically significant improvement in outcomes...

journal_title：Asia-Pacific journal of clinical oncology

authors： Wu Y,Sun WL,Feng JF

更新日期：2013-06-01 00:00:00

abstract：AIM:Important factors typically associated with prognosis in brain metastases include Karnofsky performance status (KPS), extracranial or cerebellar localization and combination chemotherapy. However, few studies investigated the prognostic role of leptomeningeal metastases (LM) following whole brain radiotherapy (WBRT...

journal_title：Asia-Pacific journal of clinical oncology

authors： Sakaguchi M,Maebayashi T,Aizawa T,Ishibashi N,Saito T

更新日期：2017-10-01 00:00:00