The outcomes of adrenalectomy for solitary adrenal metastasis: A 17-year single-center experience.

Abstract:

AIM:We aimed to analyze surgical outcomes of open or laparoscopic adrenalectomy for solitary adrenal metastasis and assess the factors influencing survival. METHODS:We retrospectively reviewed our institutional clinicopathological database for cases of adrenalectomy for solitary adrenal metastasis from solid tumors between 2000 and 2017. RESULTS:Twenty-five patients underwent open adrenalectomy (n = 11) or laparoscopic adrenalectomy (n = 14). The most common primary site was the lung (n = 7), followed by the kidney (n = 5), liver (n = 3), ovary (n = 2), soft tissue (n = 2), and six other sites. The majority of the patients (n = 19) had metachronous metastasis. The median tumor size was 3.1 cm (1-9 cm). With the median follow-up of 32 months (2-144 months), the median progression-free and overall survivals were 14 and 63 months, respectively. Multivariate analysis revealed that synchronous metastasis (hazard ratio [HR] = 7.5) and tumor size ≥ 4 cm (HR = 17.7) were significant prognostic factors for shorter overall survival. There was no significant difference for survival between the laparoscopic and open groups. CONCLUSIONS:Adrenalectomy for solitary adrenal metastasis can be applied for selected patients with various types of malignancy. However, synchronous metastasis and tumor size ≥ 4 cm were prognostic factors for shorter overall survival.

journal_name

Asia Pac J Clin Oncol

authors

Hatano K,Horii S,Nakai Y,Nakayama M,Kakimoto KI,Nishimura K

doi

10.1111/ajco.13078

subject

Has Abstract

pub_date

2020-04-01 00:00:00

pages

e86-e90

issue

2

eissn

1743-7555

issn

1743-7563

journal_volume

16

pub_type

杂志文章
  • Oral cyclophosphamide in recurrent ovarian cancer.

    abstract:AIMS:Cyclophosphamide was widely used as a single agent prior to the advent of platinum-based regimens for epithelial ovarian cancer, and, in combination with platinum, prior to the adoption of platinum and paclitaxel as standard first-line therapy. As cyclophosphamide currently has no defined role in ovarian cancer we...

    journal_title:Asia-Pacific journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1111/ajco.12074

    authors: Handolias D,Quinn M,Foo S,Mileshkin L,Grant P,Dutu G,Rischin D

    更新日期:2016-03-01 00:00:00

  • Different genetic alteration of A20 in a Sézary syndrome case with Vα2-Jα22 T cell clone.

    abstract:BACKGROUND:The comprehensive genetic alterations underlying the pathogenesis of Sézary syndrome (SS) remains largely unknown. Previous studies showed that alterations of tumor necrosis factor-α-induced protein 3 gene (TNFAIP3; A20) are frequent in SS. In this study, we characterized the mutation and polymorphisms of A2...

    journal_title:Asia-Pacific journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1111/ajco.12672

    authors: Zhou L,Zheng H,Huang X,Zhu L,Wu S,Zeng C,Yang L,Chen S,Luo G,Du X,Li Y

    更新日期:2018-04-01 00:00:00

  • Efficacy, safety and pharmacokinetics of subcutaneous azacitidine in Chinese patients with higher risk myelodysplastic syndromes: Results from a multicenter, single-arm, open-label phase 2 study.

    abstract:BACKGROUND:Azacitidine safety and efficacy were established in studies of mainly Caucasian patients. Differences in drug metabolism enzymes between Caucasian and East Asian populations prevent extrapolation of drug effects between these groups. This phase 2 study evaluated azacitidine safety, efficacy and pharmacokinet...

    journal_title:Asia-Pacific journal of clinical oncology

    pub_type: 杂志文章,多中心研究

    doi:10.1111/ajco.12835

    authors: Du X,Lai YY,Xiao Z,Liu T,Hu Y,Sun A,Li X,Shen ZX,Jin J,Yu L,Laille E,Dong Q,Songer S,Beach CL

    更新日期:2018-06-01 00:00:00

  • Endothelial cell damage induces a blood-alveolus barrier breakdown in the development of radiation-induced lung injury.

    abstract:AIM:To investigate the role of endothelial cell damage in radiation-induced lung injury. METHODS:A total of 60 male Sprague-Dawley rats were irradiated to the right hemithorax with a single dose of 0, 7.0 or 14.4 Gy. Serial studies were performed before and at 1, 7, 30 and 90 days after radiation, respectively. Pathol...

    journal_title:Asia-Pacific journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1111/j.1743-7563.2011.01461.x

    authors: Qiu J,Li J,He TC

    更新日期:2011-12-01 00:00:00

  • Systemic treatment in advanced biliary cancers: A multicenter Australian analysis and review.

    abstract:AIM:While first-line palliative chemotherapy (CT1) improves survival and quality of life in advanced biliary cancer (ABC), there is no randomized evidence to support second-line chemotherapy (CT2) in ABC. We aim to explore to role of CT2 in ABC. METHODS:We performed a retrospective review of all patients who received ...

    journal_title:Asia-Pacific journal of clinical oncology

    pub_type: 杂志文章,多中心研究,评审

    doi:10.1111/ajco.12638

    authors: Brungs D,Aghmesheh M,Sjoquist K,Goldstein D

    更新日期:2017-10-01 00:00:00

  • Early recognition of ipilimumab-related autoimmune hypophysitis in patients with metastatic melanoma: Case studies and recommendations for management.

    abstract::Ipilimumab is a human anti-CTLA-4 monoclonal antibody recently approved for the treatment of advanced melanoma. Stimulation of T-cell activity unmasks antitumor activity, but can cause immune-related adverse events. Autoimmune hypophysitis is of particular importance because its presentation can be subtle but life thr...

    journal_title:Asia-Pacific journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1111/ajco.12348

    authors: Tiu C,Pezaro C,Davis ID,Grossmann M,Parente P

    更新日期:2015-06-01 00:00:00

  • Hormone receptor positive, HER2 negative metastatic breast cancer: Impact of CDK4/6 inhibitors on the current treatment paradigm.

    abstract::Resistance to endocrine therapy is a significant therapeutic challenge in the treatment of women with hormone receptor positive (HR+), human epidermal growth factor receptor 2 negative (HER2-) advanced breast cancer. Cyclin-dependent kinase (CDK)4/6 inhibitors in combination with endocrine therapy have been shown to i...

    journal_title:Asia-Pacific journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1111/ajco.13064

    authors: Boyle F,Beith J,Burslem K,de Boer R,Hui R,Lim E,McCarthy N,Redfern A,Woodward N

    更新日期:2018-10-01 00:00:00

  • Oxaliplatin/5-fluorouracil-based adjuvant chemotherapy as a standard of care for colon cancer in clinical practice: Outcomes of the ACCElox registry.

    abstract:AIM:The ACCElox registry was set up to assess therapeutic management of early-stage colon cancer with oxaliplatin/5-fluorouracil (5-FU)-based regimen and the duration of adjuvant chemotherapy in current clinical practice. METHODS:This prospective observational study was conducted between 2006 and 2008 in 19 countries ...

    journal_title:Asia-Pacific journal of clinical oncology

    pub_type: 杂志文章,多中心研究

    doi:10.1111/ajco.12409

    authors: Park YS,Ji J,Zalcberg JR,El-Serafi M,Buzaid A,Ghosn M

    更新日期:2015-12-01 00:00:00

  • Phase II APEC trial: The impact of primary tumor side on outcomes of first-line cetuximab plus FOLFOX or FOLFIRI in patients with RAS wild-type metastatic colorectal cancer.

    abstract:AIM:The open-label, nonrandomized, phase II APEC study enrolled 167 patients with RAS wild-type (wt) metastatic colorectal cancer (mCRC) to investigate the safety and efficacy of first-line, every-2-weeks cetuximab plus investigator's choice of FOLFIRI or FOLFOX in this patient population. METHODS:A subgroup analysis ...

    journal_title:Asia-Pacific journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1111/ajco.13154

    authors: Price T,Shen L,Ma B,Esser R,Chen W,Gibbs P,Lim R,Cheng AL

    更新日期:2019-08-01 00:00:00

  • Radiation oncology during COVID-19: Strategies to avoid compromised care.

    abstract::The COVID-19 pandemic will present a range of challenges to radiation oncology departments. Early data suggest that cancer patients carry a higher than average, but still low absolute risk of hospitalization from COVID-19. The risk of severe events for those who are hospitalized however, is high. Resources for usual c...

    journal_title:Asia-Pacific journal of clinical oncology

    pub_type: 杂志文章,评审

    doi:10.1111/ajco.13456

    authors: Horsley PJ,Back M,Lamoury G,Porter B,Booth J,Eade TN

    更新日期:2021-02-01 00:00:00

  • Right versus left sided metastatic colorectal cancer: Teasing out clinicopathologic drivers of disparity in survival.

    abstract:BACKGROUND:Metastatic colorectal cancer (mCRC) patients with a right-sided primary (RC) have an inferior survival to mCRC arising from a left-sided primary (LC). Previous analyses have suggested multiple factors contribute. METHODS:The Treatment of Recurrent and Advanced Colorectal Cancer (TRACC) Registry prospectivel...

    journal_title:Asia-Pacific journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1111/ajco.13135

    authors: Mendis S,Beck S,Lee B,Lee M,Wong R,Kosmider S,Shapiro J,Yip D,Steel S,Nott L,Jennens R,Lipton L,Burge M,Field K,Ananda S,Wong HL,Gibbs P

    更新日期:2019-06-01 00:00:00

  • A study on the association between hyperlipidemia and hypothyroidism and the response to TKIs in metastatic renal cell carcinoma.

    abstract:AIM:Vascular endothelial growth facto receptor-tyrosine kinase inhibitors (VEGFR-TKIs) are widely used for metastatic renal cell carcinoma (mRCC). The aim of this study was to investigate the association between the response to VEGFR-TKIs and hyperlipidemia and hypothyroidism. METHODS:Clinical data on 155 patients wit...

    journal_title:Asia-Pacific journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1111/ajco.12473

    authors: Song Y,Du C,Zhang W,Sun Y,Yang L,Cui C,Chi Y,Shou J,Zhou A,Wang J,Sun Y

    更新日期:2016-06-01 00:00:00

  • Endoscopic self-expandable metallic stent placement in malignant pyloric or duodenal obstruction: does chemotherapy affect stent patency?

    abstract:AIM:Self-expandable metallic stents (SEMS) have been used for palliation in patients with malignant gastroduodenal obstructions. We evaluated clinical outcomes after SEMS placement and identified prognostic factors of SEMS patency, including chemotherapy. METHODS:A review of records of 85 patients with unresectable ga...

    journal_title:Asia-Pacific journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1111/j.1743-7563.2012.01590.x

    authors: Cha BH,Lee SH,Kim JE,Yoo JY,Park YS,Kim JW,Jeong SH,Kim N,Lee DH,Hwang JH

    更新日期:2013-06-01 00:00:00

  • Addition of oxaliplatin to neoadjuvant radiochemotherapy in MRI-defined T3, T4 or N+ rectal cancer: a randomized clinical trial.

    abstract:BACKGROUND:Clinical trials investigating the effects of addition of oxaliplatin to neoadjuvant radiochemotherapy in locally advanced rectal cancers (LARCs) have brought controversial results for pathologic complete response as an endpoint. This randomized clinical trial investigated downstaging as a short-term surrogat...

    journal_title:Asia-Pacific journal of clinical oncology

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/ajco.12675

    authors: Haddad P,Miraie M,Farhan F,Fazeli MS,Alikhassi A,Maddah-Safaei A,Aghili M,Kalaghchi B,Babaei M

    更新日期:2017-12-01 00:00:00

  • Pre-treatment serum lactate dehydrogenase as a biomarker in small cell lung cancer.

    abstract:BACKGROUND:Small cell lung cancer is a rapidly progressive disease with high fatality. No sensitive and specific biomarker to assist in managing this disease exists currently. AIM:Role of pretreatment serum lactate dehydrogenase as a biomarker in small cell lung cancer. METHODS:A hospital-based cancer registry was us...

    journal_title:Asia-Pacific journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1111/ajco.12674

    authors: Hsieh AH,Tahkar H,Koczwara B,Kichenadasse G,Beckmann K,Karapetis C,Sukumaran S

    更新日期:2018-04-01 00:00:00

  • Importance of health literacy in oncology.

    abstract::Health literacy refers to one's ability to obtain, process and understand health information and services to enable sound health decision-making. This is an area of increasing importance due to the complexity of the health system, especially in the cancer setting. A certain level of health literacy is required for pat...

    journal_title:Asia-Pacific journal of clinical oncology

    pub_type: 杂志文章,评审

    doi:10.1111/j.1743-7563.2012.01522.x

    authors: Koay K,Schofield P,Jefford M

    更新日期:2012-03-01 00:00:00

  • Longitudinal validation and comparison of the Chinese version of the European Organization for Research and Treatment of Cancer Quality of Life-Chemotherapy-Induced Peripheral Neuropathy Questionnaire (EORTC QLQ-CIPN20) and the Functional Assessment of Ca

    abstract:AIM:To validate and compare the Chinese version of the European Organization for Research and Treatment of Cancer Quality of Life-Chemotherapy-Induced Peripheral Neuropathy Questionnaire (EORTC QLQ-CIPN20) and the Functional Assessment of Cancer-Gynecologic Oncology Group-Neurotoxicity subscale (FACT/GOG-Ntx) for measu...

    journal_title:Asia-Pacific journal of clinical oncology

    pub_type: 杂志文章,多中心研究

    doi:10.1111/ajco.13000

    authors: Cheng HL,Molassiotis A

    更新日期:2019-02-01 00:00:00

  • The significance of subcarinal dissection in esophageal cancer surgery.

    abstract:AIM:The purpose of this study was to investigate the impact of subcarinal dissection on short-term outcome and survival following esophagectomy in patients with thoracic esophageal squamous cell carcinoma. METHODS:A total of 2252 patients underwent an esophagectomy for esophageal cancer from January 1997 to December 2...

    journal_title:Asia-Pacific journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1111/ajco.12095

    authors: Hu W,Liang Y,Zhang S,Hu Y,Liu J

    更新日期:2014-06-01 00:00:00

  • Pathological outcomes in rectal cancer following laparoscopic surgery.

    abstract:AIM:This study examined pathological quality-of-surgery indicators in laparoscopic and open rectal cancer resection specimens. METHODS:Retrospective analysis of consecutive, prospectively recorded laparoscopic (LR) or open (OR) resections for rectal cancer. Indicators included integrity of the perirectal fascial envel...

    journal_title:Asia-Pacific journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1111/ajco.12781

    authors: Cheung HYC,Dent OF,Richardson GL,Chan C,Keshava A,Young CJ

    更新日期:2018-04-01 00:00:00

  • Inadequate treatment practices for pain relief and adverse event management in cancer patients across 10 countries/regions in Asia: a call for greater efforts to improve standards for patient care.

    abstract:AIM:To examine the treatment practices for cancer pain relief and adverse event management, and the factors related to patient outcomes in the participating countries/regions. METHODS:The study was a cross-sectional survey conducted between September and December 2013 in 10 countries/regions across Asia. Adult patient...

    journal_title:Asia-Pacific journal of clinical oncology

    pub_type: 杂志文章,多中心研究

    doi:10.1111/ajco.12696

    authors: Ho KY,Ahn JS,Calimag MM,Chao TC,Kim YC,Moon H,Tho LM,Xia ZJ,You D

    更新日期:2018-06-01 00:00:00

  • Primary tumor location is an important predictive factor for wild-type KRAS metastatic colon cancer treated with cetuximab as front-line bio-therapy.

    abstract:INTRODUCTION:Left- and right-sided colon cancers were significantly different in epidemiologic, clinical and histological parameters. However, the impact of primary tumor location in metastatic colon cancer treated with front-line targeted triplet regimens is unclear, particularly in Asian populations. METHODS:A total...

    journal_title:Asia-Pacific journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1111/ajco.12469

    authors: Lu HJ,Lin JK,Chen WS,Jiang JK,Yang SH,Lan YT,Lin CC,Chang SC,Teng HW

    更新日期:2016-09-01 00:00:00

  • Cancer multidisciplinary team meetings in practice: Results from a multi-institutional quantitative survey and implications for policy change.

    abstract:AIM:Multidisciplinary care is advocated as best practice in cancer care. Relatively little is documented about multidisciplinary team (MDT) meeting functioning, decision making and the use of evidence to support decision making in Australia. This descriptive study aimed to examine team functioning, the role of team mee...

    journal_title:Asia-Pacific journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1111/ajco.12765

    authors: Rankin NM,Lai M,Miller D,Beale P,Spigelman A,Prest G,Turley K,Simes J

    更新日期:2018-02-01 00:00:00

  • Potential issues with complementary medicines commonly used in the cancer population: A retrospective review of a tertiary cancer center's experience.

    abstract:AIM:Complementary medicine (CAM) use in the cancer population is higher than the general population: some studies estimate up to 70%. Our Medicines Information Centre, in a tertiary cancer institution, receives many enquiries regarding use and safety of CAM with conventional cancer therapies (chemotherapy, radiotherapy...

    journal_title:Asia-Pacific journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1111/ajco.13026

    authors: Brooks SL,Rowan G,Michael M

    更新日期:2018-10-01 00:00:00

  • Positive sentinel lymph node metastasis from a metastasis in Melanoma.

    abstract::The rationale for certain patterns of metastatic spread seen in melanoma is not well understood. Currently, there is no clear experimental evidence to support the potential for metastases to form metastases in this disease. We report a case of a 31-year-old woman, with metastatic melanoma, who developed axillary lymph...

    journal_title:Asia-Pacific journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1111/ajco.12169

    authors: Bowyer S,Feeney K,Millward M

    更新日期:2014-12-01 00:00:00

  • Survival of lung cancer patients in a resource-limited country.

    abstract:AIM:Data on lung cancer survival are lacking in developing countries. Our objectives were to describe the survival of our lung cancer patients and to determine independent prognostic factors affecting survival. METHOD:All patients diagnosed with lung cancer from August 2007 to August 2010 were recruited from a single ...

    journal_title:Asia-Pacific journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1111/ajco.12179

    authors: How SH,Ng TH,Kuan YC,Jamalludin AR,Fauzi AR

    更新日期:2015-09-01 00:00:00

  • Serious hepatic complications of selective internal radiation therapy with yttrium-90 microsphere radioembolization for unresectable liver tumors.

    abstract:AIM:Selective internal radiation therapy with yttrium-90 microsphere radioembolization has been used to treat unresectable liver tumors and its acute toxicity has been well described. Subacute and long-term hepatic complications related to radioembolization however may be underreported in the literature. This retrospec...

    journal_title:Asia-Pacific journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1111/ajco.12229

    authors: Kuo JC,Tazbirkova A,Allen R,Kosmider S,Gibbs P,Yip D

    更新日期:2014-09-01 00:00:00

  • Insights into the cell of origin in breast cancer and breast cancer stem cells.

    abstract::The precise cell types that give rise to tumors and mechanisms that underpin tumor heterogeneity are poorly understood. There is increasing evidence to suggest that diverse solid tumors are hierarchically organized and may be sustained by a distinct subpopulation of cancer stem cells (CSCs). The CSC hypothesis provide...

    journal_title:Asia-Pacific journal of clinical oncology

    pub_type: 杂志文章,评审

    doi:10.1111/j.1743-7563.2010.01279.x

    authors: Lindeman GJ,Visvader JE

    更新日期:2010-06-01 00:00:00

  • Serum CA 19-9 as a prognostic factor in patients with metastatic gastric cancer.

    abstract:AIM:To evaluate tumor markers as prognostic factors in patients with metastatic or recurrent gastric cancer receiving first-line chemotherapy. METHODS:Between January 2000 and December 2008, 1178 patients with metastatic or recurrent gastric cancer were assayed for expression of three serum tumor markers, CA 19-9, CA ...

    journal_title:Asia-Pacific journal of clinical oncology

    pub_type: 杂志文章

    doi:10.1111/ajco.12019

    authors: Jo JC,Ryu MH,Koo DH,Ryoo BY,Kim HJ,Kim TW,Choi KD,Lee GH,Jung HY,Yook JH,Oh ST,Kim BS,Kim JH,Kang YK

    更新日期:2013-12-01 00:00:00

  • Interventions to improve patient participation in the treatment process for culturally and linguistically diverse people with cancer: a systematic review.

    abstract::Disparities in cancer outcomes for people from culturally and linguistically diverse (CALD) groups are well known. Improving CALD patients' active participation in treatment processes holds potential to improve outcomes, but little is known of effective strategies to facilitate this. This systematic review investigate...

    journal_title:Asia-Pacific journal of clinical oncology

    pub_type: 杂志文章,评审

    doi:10.1111/j.1743-7563.2012.01531.x

    authors: Harun A,Harrison JD,Young JM

    更新日期:2013-06-01 00:00:00

  • Immunotherapy for urothelial carcinoma: Metastatic disease and beyond.

    abstract::For advanced and metastatic urothelial carcinomas (UCs), platinum (preferably cisplatin)-based chemotherapy has been the standard treatment for many years. However, many patients are ineligible for cisplatin-based chemotherapy because of poor performance status and/or other age-related conditions. At the other end of ...

    journal_title:Asia-Pacific journal of clinical oncology

    pub_type: 杂志文章,评审

    doi:10.1111/ajco.13312

    authors: Poon DM

    更新日期:2020-09-01 00:00:00