Cabazitaxel in patients with metastatic castration-resistant prostate cancer: safety and quality of life data from the Australian early access program.

abstract：BACKGROUND:Primary squamous cell carcinoma of the breast (PSCCB) is a rare clinical classification of breast tumors. Little is known about its clinicopathological features, prognosis and potential therapeutic strategies. The purpose of this study is to evaluate the effect of postoperative radiotherapy (PORT) on patient...

journal_title：Asia-Pacific journal of clinical oncology

authors： Wang X,Zhang L,Luo J,Jin K,Yang Z,Meng J,Zhang X,Zhang Z,Shao Z,Guo X,Chen X,Yu X

更新日期：2020-10-20 00:00:00

abstract：:Ipilimumab is a human anti-CTLA-4 monoclonal antibody recently approved for the treatment of advanced melanoma. Stimulation of T-cell activity unmasks antitumor activity, but can cause immune-related adverse events. Autoimmune hypophysitis is of particular importance because its presentation can be subtle but life thr...

journal_title：Asia-Pacific journal of clinical oncology

authors： Tiu C,Pezaro C,Davis ID,Grossmann M,Parente P

更新日期：2015-06-01 00:00:00

abstract：AIM:To evaluate tumor markers as prognostic factors in patients with metastatic or recurrent gastric cancer receiving first-line chemotherapy. METHODS:Between January 2000 and December 2008, 1178 patients with metastatic or recurrent gastric cancer were assayed for expression of three serum tumor markers, CA 19-9, CA ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Jo JC,Ryu MH,Koo DH,Ryoo BY,Kim HJ,Kim TW,Choi KD,Lee GH,Jung HY,Yook JH,Oh ST,Kim BS,Kim JH,Kang YK

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:To review the outcomes of metastatic melanoma patients treated with infliximab for severe steroid-refractory colitis secondary to ipilimumab therapy. BACKGROUND:Immune-related colitis is a known potential adverse effect of ipilimumab, that causes significant morbidity and extended hospital stays. There are l...

journal_title：Asia-Pacific journal of clinical oncology

authors： Hillock NT,Heard S,Kichenadasse G,Hill CL,Andrews J

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Providing appropriate educational resources to patients with head and neck cancer (HNC) is important but challenging. The aim of this study was to determine Australian clinicians' perceptions of currently used HNC information resources. METHODS:A purpose-designed questionnaire was disseminated electronicall...

journal_title：Asia-Pacific journal of clinical oncology

authors： Jabbour J,Wykes J,Milross C,Sundaresan P,Ebrahimi A,Shepherd HL,Dhillon HM,Clark JR

更新日期：2018-10-01 00:00:00

abstract：:Cancer, its therapy, and related adverse effects have been associated with reduced work performance, including absenteeism (i.e. absence from scheduled work due to health problems) and presenteeism (i.e. impaired on-the-job performance due to health problems) among cancer survivors. This review aimed to compare the wo...

journal_title：Asia-Pacific journal of clinical oncology

authors： Soejima T,Kamibeppu K

更新日期：2016-12-01 00:00:00

abstract：AIM:To assess the prognostic significance of enhancement rate (ER) measured by contrast-enhanced ultrasonography (CEUS) in patients with hepatocellular carcinoma (HCC) undergoing radiofrequency ablation (RFA). MATERIALS AND METHODS:A total of 253 patients with single primary HCC undergoing preoperative CEUS and RFA we...

journal_title：Asia-Pacific journal of clinical oncology

authors： Zhou G,Cai ZQ,Luo J,Hu ZX,Luo H,Wu H,Chen Q

更新日期：2019-08-01 00:00:00

abstract：INTRODUCTION:The goal of this study was to determine the relationships among type 2 diabetes mellitus (DM), specific cancer histological types and mortality in hospitalized women. METHODS:Patients over 19 years of age were included if the indication for hospital admission was a diagnosis of type 2 DM or a malignancy. ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Chen JY,Chiou WK,Chou WY,Lin JD

更新日期：2016-03-01 00:00:00

abstract：:It is important to distinguish between tumor recurrence and treatment effects in posttreatment patients with high-grade gliomas. Several imaging modalities have been reported in differentiating between tumor recurrence and treatment effects. However, there were no consistent conclusions between different studies. We p...

journal_title：Asia-Pacific journal of clinical oncology

authors： Wang X,Hu X,Xie P,Li W,Li X,Ma L

更新日期：2015-06-01 00:00:00

abstract：AIM:The ACCElox registry was set up to assess therapeutic management of early-stage colon cancer with oxaliplatin/5-fluorouracil (5-FU)-based regimen and the duration of adjuvant chemotherapy in current clinical practice. METHODS:This prospective observational study was conducted between 2006 and 2008 in 19 countries ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Park YS,Ji J,Zalcberg JR,El-Serafi M,Buzaid A,Ghosn M

更新日期：2015-12-01 00:00:00

abstract：AIMS:In this study, we intended to analyze the clinical significance of CD4+ FoxP3+ Tregs in gastric cancer patients and investigate the relationship between the proportion of CD4+ FoxP3+ Tregs in the peripheral blood and the expression of FoxM1 and Ki-67 in gastric cancer tissues. METHODS:Flow cytometry was used to m...

journal_title：Asia-Pacific journal of clinical oncology

authors： Ma K,Li X,Lv J,Liu Z,Zhang L,Cong H,Wang H,Shen F,Yue L

更新日期：2020-01-19 00:00:00

abstract：AIM:The open-label, nonrandomized, phase II APEC study enrolled 167 patients with RAS wild-type (wt) metastatic colorectal cancer (mCRC) to investigate the safety and efficacy of first-line, every-2-weeks cetuximab plus investigator's choice of FOLFIRI or FOLFOX in this patient population. METHODS:A subgroup analysis ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Price T,Shen L,Ma B,Esser R,Chen W,Gibbs P,Lim R,Cheng AL

更新日期：2019-08-01 00:00:00

abstract：AIMS:The Australian Institute of Health and Welfare (AIHW) is a major national agency established by the Australian government to provide information and statistics on Australia's health and welfare. The AIHW and the Australasian Association of Cancer Registries collaborate every year to provide updated information on ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Australian Institute of Health and Welfare.

更新日期：2013-09-01 00:00:00

abstract：AIM:Metadherin (MTDH) is a potential oncogene in tumor development and is highly expressed in various types of human cancers. However, there has been no report on the role of MTDH in bladder cancer. Our aim was to investigate the expression pattern of MTDH in bladder tissue at different clinic pathological stages and e...

journal_title：Asia-Pacific journal of clinical oncology

authors： Zhou J,Li J,Wang Z,Yin C,Zhang W

更新日期：2012-09-01 00:00:00

abstract：AIMS:Wilms tumor (WT) is rare in Asia. Treatment of bilateral WT is challenging, and the treatment outcome of bilateral WT is rarely reported in low incidence areas. METHODS:We enrolled patients with bilateral WT registered in Chang Gung Memorial Hospital, Taoyuan, Taiwan, between January 1986 and June 2015. They were...

journal_title：Asia-Pacific journal of clinical oncology

authors： Chen SH,Hung IJ,Yang CP,Jaing TH,Wang CJ,Hsueh C,Lai JY

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Anti-HER2 therapy-related cardiotoxicity is well described in the context of clinical trials, particularly in the setting of early stage disease, but there is more limited data in advanced breast cancer and in the real world setting. MATERIAL AND METHODS:A prospectively-maintained registry database with 312...

journal_title：Asia-Pacific journal of clinical oncology

authors： Conduit C,de Boer RH,Lok S,Gibbs P,Malik L,Loh Z,Yeo B,Greenberg S,Devitt B,Lombard J,Nottage M,Collins I,Torres J,Nolan M,Nott L

更新日期：2020-12-01 00:00:00

abstract：:Carboplatin is a platinum analogue, widely used in the treatment of numerous cancer types including lung, genitourinary and ovarian cancers. It is also used in the adjuvant treatment of human epidermal growth factor receptor 2 positive breast cancer, where a non-anthracycline regimen is preferred. It is considered gen...

journal_title：Asia-Pacific journal of clinical oncology

authors： Turner N,Stewart J,Barnett F,White S

更新日期：2012-09-01 00:00:00

abstract：AIM:Multidisciplinary care is advocated as best practice in cancer care. Relatively little is documented about multidisciplinary team (MDT) meeting functioning, decision making and the use of evidence to support decision making in Australia. This descriptive study aimed to examine team functioning, the role of team mee...

journal_title：Asia-Pacific journal of clinical oncology

authors： Rankin NM,Lai M,Miller D,Beale P,Spigelman A,Prest G,Turley K,Simes J

更新日期：2018-02-01 00:00:00

abstract：AIM:Self-expandable metallic stents (SEMS) have been used for palliation in patients with malignant gastroduodenal obstructions. We evaluated clinical outcomes after SEMS placement and identified prognostic factors of SEMS patency, including chemotherapy. METHODS:A review of records of 85 patients with unresectable ga...

journal_title：Asia-Pacific journal of clinical oncology

authors： Cha BH,Lee SH,Kim JE,Yoo JY,Park YS,Kim JW,Jeong SH,Kim N,Lee DH,Hwang JH

更新日期：2013-06-01 00:00:00

abstract：AIM:To carry out a nationwide study of KRAS testing in metastatic colorectal cancer as reported by nine major molecular pathology service providers in Australia, including mutation frequencies and turnaround times that might impact on patient care. METHODS:Participating laboratories contributed information on KRAS mut...

journal_title：Asia-Pacific journal of clinical oncology

authors： Scott RJ,Fox SB,Desai J,Grieu F,Amanuel B,Garrett K,Harraway J,Cheetham G,Pattle N,Haddad A,Byron K,Rudzki B,Waring P,Iacopetta B

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Docetaxel is an effective therapy for metastatic castration-resistant prostate cancer (mCRPC); however, many patients experience febrile neutropenia (FN) and cease treatment early due to toxicity. It is not known whether lower dose (LD) q3-weekly docetaxel impacts toxicity or efficacy. METHODS:Multicenter r...

journal_title：Asia-Pacific journal of clinical oncology

authors： Hamid AA,Willson K,Vincent AD,Tamjid B,Lee M,Bergin A,Gan C,Campbell A,Stewart J,Pezaro C,Tran B,Weickhardt AJ

更新日期：2018-10-01 00:00:00

abstract：AIM:We aimed to analyze surgical outcomes of open or laparoscopic adrenalectomy for solitary adrenal metastasis and assess the factors influencing survival. METHODS:We retrospectively reviewed our institutional clinicopathological database for cases of adrenalectomy for solitary adrenal metastasis from solid tumors be...

journal_title：Asia-Pacific journal of clinical oncology

authors： Hatano K,Horii S,Nakai Y,Nakayama M,Kakimoto KI,Nishimura K

更新日期：2020-04-01 00:00:00

abstract：AIM:As survival rates for aggressive and conservative breast and lymph node surgery are similar, surgical treatment decisions for patients with early-stage breast cancer should take patient preference into account. Decision aids have been demonstrated to increase patient knowledge and satisfaction with decision making,...

journal_title：Asia-Pacific journal of clinical oncology

authors： Harwood R,Douglas C,Clark D

更新日期：2011-06-01 00:00:00

abstract：:The rationale for certain patterns of metastatic spread seen in melanoma is not well understood. Currently, there is no clear experimental evidence to support the potential for metastases to form metastases in this disease. We report a case of a 31-year-old woman, with metastatic melanoma, who developed axillary lymph...

journal_title：Asia-Pacific journal of clinical oncology

authors： Bowyer S,Feeney K,Millward M

更新日期：2014-12-01 00:00:00

abstract：AIM:Behavioral interventions such as exercise may induce epigenetic changes. Only few studies investigated the effects of exercise on epigenetic alterations in colorectal cancer survivors. The aim of this study was to explore the changes of genome-wide DNA methylation after 6-week exercise training in colorectal cancer...

journal_title：Asia-Pacific journal of clinical oncology

authors： Hwang SH,Kang DW,Lee MK,Byeon JY,Park H,Park DH,Kim KC,Lee ST,Chu SH,Kim NK,Jeon JY

更新日期：2020-10-13 00:00:00

abstract：BACKGROUND:Small cell lung cancer is a rapidly progressive disease with high fatality. No sensitive and specific biomarker to assist in managing this disease exists currently. AIM:Role of pretreatment serum lactate dehydrogenase as a biomarker in small cell lung cancer. METHODS:A hospital-based cancer registry was us...

journal_title：Asia-Pacific journal of clinical oncology

authors： Hsieh AH,Tahkar H,Koczwara B,Kichenadasse G,Beckmann K,Karapetis C,Sukumaran S

更新日期：2018-04-01 00:00:00

abstract：AIM:We investigated prognostic significance of methylation status of MASPIN gene and its protein expression in normal subjects, cholelithiasis and gallbladder cancer (GBC) patients. METHODS:MASPIN protein expression and its promoter methylation in gallbladder tissue of cholelithiasis (n = 36), GBC (n = 46) and control...

journal_title：Asia-Pacific journal of clinical oncology

authors： Baghel K,Kazmi HR,Chandra A,Raj S,Srivastava RN

更新日期：2019-10-01 00:00:00

abstract：AIM:While first-line palliative chemotherapy (CT1) improves survival and quality of life in advanced biliary cancer (ABC), there is no randomized evidence to support second-line chemotherapy (CT2) in ABC. We aim to explore to role of CT2 in ABC. METHODS:We performed a retrospective review of all patients who received ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Brungs D,Aghmesheh M,Sjoquist K,Goldstein D

更新日期：2017-10-01 00:00:00

abstract：AIM:This systematic review and meta-analysis was performed to assess the efficacy and side effects between single-agent and doublet chemotherapy in first-line treatment of advanced non-small cell lung cancer with performance status 2 (PS2). METHODS:We searched for randomized controlled trials in online electronic data...

journal_title：Asia-Pacific journal of clinical oncology

authors： Luo L,Hu Q,Jiang JX,Yang X,Dinglin XX,Lin X,Yao HR

更新日期：2015-09-01 00:00:00

abstract：:First-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are used as first-line therapy in patients with non-small cell lung cancer (NSCLC) harboring a sensitizing mutation in the EGFR gene. Unfortunately, resistance to these therapies often occurs within 10 months of commencing treat...

journal_title：Asia-Pacific journal of clinical oncology

authors： John T,Bowden JJ,Clarke S,Fox SB,Garrett K,Horwood K,Karapetis CS

更新日期：2017-08-01 00:00:00