The efficacy of axitinib as a first-line treatment for metastatic renal cell carcinoma.

abstract：AIM:The ACCElox registry was set up to assess therapeutic management of early-stage colon cancer with oxaliplatin/5-fluorouracil (5-FU)-based regimen and the duration of adjuvant chemotherapy in current clinical practice. METHODS:This prospective observational study was conducted between 2006 and 2008 in 19 countries ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Park YS,Ji J,Zalcberg JR,El-Serafi M,Buzaid A,Ghosn M

更新日期：2015-12-01 00:00:00

abstract：AIM:To evaluate the attitudes of patients with different cancers towards research biopsies outside a clinical trial. METHODS:Patients with metastatic cancer completed a questionnaire that assessed patients' willingness to consider research biopsies. Research biopsies were divided into two groups: biopsies performed as...

journal_title：Asia-Pacific journal of clinical oncology

authors： Robinson DH,Churilov L,Lin NU,Lim E,Seah D

更新日期：2018-06-01 00:00:00

abstract：AIM:This multicenter, observational study aimed to investigate the survival benefit of eribulin as well as that of taxane-based regimens in Japanese patients with metastatic breast cancer (MBC) in a real-world setting. METHODS:This study enrolled women with MBC who received eribulin or taxane-based regimens with or wi...

journal_title：Asia-Pacific journal of clinical oncology

authors： Kikuchi Y,Uchida Y,Shirakawa K,Kanauchi H,Niwa T,Nishioka K,Tada K,Hashimoto M,Yasuda H,Sugiura R,Kawabata H,Seto Y,Ogawa T

更新日期：2018-10-01 00:00:00

abstract：:We report a case of acute inflammatory demyelinating polyradiculoneuropathy (AIDP) that developed in a patient with cholangiocarcinoma after receiving oxaliplatin-based chemotherapy. A 62-year-old man had multiple hypodense lesions with delayed enhancement in the both lobes of the liver on abdominal computed tomograph...

journal_title：Asia-Pacific journal of clinical oncology

authors： Yoon JY,Nam TS,Kim MK,Hwang JE,Shim HJ,Cho SH,Chung IJ,Bae WK

更新日期：2012-06-01 00:00:00

abstract：AIMS:The optimal maintenance therapy for patients with acute promyelocytic leukemia (APL) who achieved complete remission (CR) and complete consolidation chemotherapy is still controversial. Whether the use of arsenic trioxide (ATO) alone or along with all-trans retinoic acid (ATRA) improves overall survival (OS) or di...

journal_title：Asia-Pacific journal of clinical oncology

authors： Chiang YH,Chang YF,Hsieh RK,Lin J,Chen CG,Lim KH,Lin HC,Chang MC

更新日期：2012-12-01 00:00:00

abstract：AIMS:There is currently no routine collection of cancer stages in population-based data in Australia. This study evaluates the accuracy of International classification of diseases (ICD) codes for secondary neoplasms recorded in hospital morbidity data to assign spread of disease at diagnosis for colorectal cancer. MET...

journal_title：Asia-Pacific journal of clinical oncology

authors： Thompson B,Lumley J,Coory M

更新日期：2012-09-01 00:00:00

abstract：:Cancer in pregnancy may be increasing in incidence with advancing maternal age and higher rates of obesity. The diagnosis of cancer in pregnancy provokes complex management issues balancing short- and long-term risks for both mother and baby. Every case needs to be individualized, with a multidisciplinary team of midw...

journal_title：Asia-Pacific journal of clinical oncology

authors： Eastwood-Wilshere N,Turner J,Oliveira N,Morton A

更新日期：2019-12-01 00:00:00

abstract：:It is important to distinguish between tumor recurrence and treatment effects in posttreatment patients with high-grade gliomas. Several imaging modalities have been reported in differentiating between tumor recurrence and treatment effects. However, there were no consistent conclusions between different studies. We p...

journal_title：Asia-Pacific journal of clinical oncology

authors： Wang X,Hu X,Xie P,Li W,Li X,Ma L

更新日期：2015-06-01 00:00:00

abstract：AIM:As survival rates for aggressive and conservative breast and lymph node surgery are similar, surgical treatment decisions for patients with early-stage breast cancer should take patient preference into account. Decision aids have been demonstrated to increase patient knowledge and satisfaction with decision making,...

journal_title：Asia-Pacific journal of clinical oncology

authors： Harwood R,Douglas C,Clark D

更新日期：2011-06-01 00:00:00

abstract：:Resistance to endocrine therapy is a significant therapeutic challenge in the treatment of women with hormone receptor positive (HR+), human epidermal growth factor receptor 2 negative (HER2-) advanced breast cancer. Cyclin-dependent kinase (CDK)4/6 inhibitors in combination with endocrine therapy have been shown to i...

journal_title：Asia-Pacific journal of clinical oncology

authors： Boyle F,Beith J,Burslem K,de Boer R,Hui R,Lim E,McCarthy N,Redfern A,Woodward N

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:The comprehensive genetic alterations underlying the pathogenesis of Sézary syndrome (SS) remains largely unknown. Previous studies showed that alterations of tumor necrosis factor-α-induced protein 3 gene (TNFAIP3; A20) are frequent in SS. In this study, we characterized the mutation and polymorphisms of A2...

journal_title：Asia-Pacific journal of clinical oncology

authors： Zhou L,Zheng H,Huang X,Zhu L,Wu S,Zeng C,Yang L,Chen S,Luo G,Du X,Li Y

更新日期：2018-04-01 00:00:00

abstract：AIM:For several decades urinary arylsulfatase (ARS) activity has been reported to be elevated in many cancers. It has been shown that urinary ARS activity may serve as a marker of tumor progression and therapy surveillance. This study was designed to evaluate the clinical application of detection of urinary ARS activit...

journal_title：Asia-Pacific journal of clinical oncology

authors： Niu R,Jing H,Chen Z,Xu J,Dai J,Yan Z

更新日期：2012-12-01 00:00:00

abstract：AIM:Mucositis is a major complication of irradiation in head and neck tumors, the addition of chemotherapy to irradiation may enhance this dose-limiting problem. Licorice is a strong demulcent that had been effectively used in treatment of peptic ulcer. The main purpose of this study was to compare the therapeutic safe...

journal_title：Asia-Pacific journal of clinical oncology

authors： Ghalayani P,Emami H,Pakravan F,Nasr Isfahani M

更新日期：2017-04-01 00:00:00

abstract：AIMS:To evaluate the response and progression-free survival (PFS) of Malaysian patients with advanced lung adenocarcinoma and unknown epidermal growth factor receptor (EGFR) mutation status treated with gefitinib. METHODS:A retrospective analysis of consecutive patients with EGFR mutation unknown stage III or IV lung ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Liam CK,Ruthranesan M,Lee CH,Pang YK,Chua KT,Lim BK

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Docetaxel is an effective therapy for metastatic castration-resistant prostate cancer (mCRPC); however, many patients experience febrile neutropenia (FN) and cease treatment early due to toxicity. It is not known whether lower dose (LD) q3-weekly docetaxel impacts toxicity or efficacy. METHODS:Multicenter r...

journal_title：Asia-Pacific journal of clinical oncology

authors： Hamid AA,Willson K,Vincent AD,Tamjid B,Lee M,Bergin A,Gan C,Campbell A,Stewart J,Pezaro C,Tran B,Weickhardt AJ

更新日期：2018-10-01 00:00:00

abstract：AIM:Gastric cancer patients are normally treated with oral fluoropyrimidine and cisplatin or oxaliplatin; however, treating patients who also have a gastrointestinal obstruction is often difficult because of their poor oral intake. Instead, a modified (m)FOLFOX-6 regimen is administered, even to patients with gastroint...

journal_title：Asia-Pacific journal of clinical oncology

authors： Yukami H,Terazawa T,Goto M,Aoki M,Asaishi K,Yamaguchi T,Kuwakado S,Kii T,Higuchi K

更新日期：2019-10-01 00:00:00

abstract：AIM:To investigate the association between plasma visfatin levels and risk of early and advanced colorectal cancer (CRC). METHODS:In total, 358 CRC patients and 286 controls were enrolled. According to the T factor of the TNM system. cancer patients were divided into two subgroups: early and advanced cancer. Levels of...

journal_title：Asia-Pacific journal of clinical oncology

authors： Chen M,Wang Y,Li Y,Zhao L,Ye S,Wang S,Yu C,Xie H

更新日期：2016-03-01 00:00:00

abstract：AIM:The effect of transcatheter arterial chemoembolization (TACE) therapy on hepatitis B virus (HBV) reactivation in hepatocellular carcinoma (HCC) patients with prior resolved hepatitis B is not fully understood. METHODS:From January 2006 to December 2010, 43 hepatitis B surface antigen (HBsAg)-negative/anti-hepatiti...

journal_title：Asia-Pacific journal of clinical oncology

authors： Peng JW,Lin GN,Xiao JJ,Jiang XM

更新日期：2012-12-01 00:00:00

abstract：AIM:Elevated neutrophil-to-lymphocyte ratio (NLR) has been demonstrated to be a poor prognostic factor in multiple types of malignancies, whereas the effect of NLR on the prognosis of epidermal growth factor receptor (EGFR)-mutated advanced non-small-cell lung cancer (NSCLC) patients treated with first-line EGFR tyrosi...

journal_title：Asia-Pacific journal of clinical oncology

authors： Lin GN,Peng JW,Liu PP,Liu DY,Xiao JJ,Chen XQ

更新日期：2017-10-01 00:00:00

abstract：AIM:For early-stage breast cancer, four cycles of docetaxel and cyclophosphamide (TC) was proven superior to doxorubicin plus cyclophosphamide in the US Oncology 9375 trial. Given primary prophylactic antibiotics, 5% febrile neutropenia was recorded in a population comprising 75.5% Caucasians. Smaller trials and retros...

journal_title：Asia-Pacific journal of clinical oncology

authors： Chow LWC,Biganzoli L,Leo AD,Kuroi K,Han HS,Patel J,Huang CS,Lu YS,Zhu L,Chow CYC,Loo WTY,Glück S,Toi M

更新日期：2017-12-01 00:00:00

abstract：AIM:To validate and compare the Chinese version of the European Organization for Research and Treatment of Cancer Quality of Life-Chemotherapy-Induced Peripheral Neuropathy Questionnaire (EORTC QLQ-CIPN20) and the Functional Assessment of Cancer-Gynecologic Oncology Group-Neurotoxicity subscale (FACT/GOG-Ntx) for measu...

journal_title：Asia-Pacific journal of clinical oncology

authors： Cheng HL,Molassiotis A

更新日期：2019-02-01 00:00:00

abstract：:Non-small cell lung cancers (NSCLC) harboring the uncommon epidermal growth factor receptor (EGFR) exon 20 insertion mutations are generally thought to be unresponsive to EGFR-tyrosine kinase inhibitor (TKI) therapy. Presented here is a case of stage IV NSCLC harboring an uncommon EGFR exon 20 insertion mutation that ...

journal_title：Asia-Pacific journal of clinical oncology

authors： Chan RT

更新日期：2018-03-01 00:00:00

abstract：AIMS:Esophageal cancer (EC) is one of the most prevalent and deadly cancers worldwide. Along with nutrition, smoking and alcohol consumption, human papillomavirus (HPV) infection is one of the major risk factors, which is modulated by host immune response. This study is aimed at elucidating how HPV modifies host immune...

journal_title：Asia-Pacific journal of clinical oncology

authors： Feng B,Awuti I,Deng Y,Li D,Niyazi M,Aniwar J,Sheyhidin I,Lu G,Li G,Zhang L

更新日期：2014-03-01 00:00:00

abstract：AIM:Self-expandable metallic stents (SEMS) have been used for palliation in patients with malignant gastroduodenal obstructions. We evaluated clinical outcomes after SEMS placement and identified prognostic factors of SEMS patency, including chemotherapy. METHODS:A review of records of 85 patients with unresectable ga...

journal_title：Asia-Pacific journal of clinical oncology

authors： Cha BH,Lee SH,Kim JE,Yoo JY,Park YS,Kim JW,Jeong SH,Kim N,Lee DH,Hwang JH

更新日期：2013-06-01 00:00:00

abstract：AIM:Cabazitaxel is a next generation taxane that has been shown to improve overall survival in patients with metastatic castration-resistant prostate cancer (mCRPC) whose disease progressed during or after docetaxel-based therapy. A worldwide early access program (EAP) study was established to provide access to cabazit...

journal_title：Asia-Pacific journal of clinical oncology

authors： Parente P,Ng S,Parnis F,Guminski A,Gurney H

更新日期：2017-12-01 00:00:00

abstract：AIM:To assess the prognostic significance of enhancement rate (ER) measured by contrast-enhanced ultrasonography (CEUS) in patients with hepatocellular carcinoma (HCC) undergoing radiofrequency ablation (RFA). MATERIALS AND METHODS:A total of 253 patients with single primary HCC undergoing preoperative CEUS and RFA we...

journal_title：Asia-Pacific journal of clinical oncology

authors： Zhou G,Cai ZQ,Luo J,Hu ZX,Luo H,Wu H,Chen Q

更新日期：2019-08-01 00:00:00

abstract：INTRODUCTION:Left- and right-sided colon cancers were significantly different in epidemiologic, clinical and histological parameters. However, the impact of primary tumor location in metastatic colon cancer treated with front-line targeted triplet regimens is unclear, particularly in Asian populations. METHODS:A total...

journal_title：Asia-Pacific journal of clinical oncology

authors： Lu HJ,Lin JK,Chen WS,Jiang JK,Yang SH,Lan YT,Lin CC,Chang SC,Teng HW

更新日期：2016-09-01 00:00:00

abstract：:First-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are used as first-line therapy in patients with non-small cell lung cancer (NSCLC) harboring a sensitizing mutation in the EGFR gene. Unfortunately, resistance to these therapies often occurs within 10 months of commencing treat...

journal_title：Asia-Pacific journal of clinical oncology

authors： John T,Bowden JJ,Clarke S,Fox SB,Garrett K,Horwood K,Karapetis CS

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Providing appropriate educational resources to patients with head and neck cancer (HNC) is important but challenging. The aim of this study was to determine Australian clinicians' perceptions of currently used HNC information resources. METHODS:A purpose-designed questionnaire was disseminated electronicall...

journal_title：Asia-Pacific journal of clinical oncology

authors： Jabbour J,Wykes J,Milross C,Sundaresan P,Ebrahimi A,Shepherd HL,Dhillon HM,Clark JR

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:Metastatic colorectal cancer (mCRC) patients with a right-sided primary (RC) have an inferior survival to mCRC arising from a left-sided primary (LC). Previous analyses have suggested multiple factors contribute. METHODS:The Treatment of Recurrent and Advanced Colorectal Cancer (TRACC) Registry prospectivel...

journal_title：Asia-Pacific journal of clinical oncology

authors： Mendis S,Beck S,Lee B,Lee M,Wong R,Kosmider S,Shapiro J,Yip D,Steel S,Nott L,Jennens R,Lipton L,Burge M,Field K,Ananda S,Wong HL,Gibbs P

更新日期：2019-06-01 00:00:00