Abstract：
:In the century since Paul Portier and Charles Richet described their landmark findings of severe fatal reactions in dogs re-exposed to venom after vaccination with sea anemone venom, treatment for anaphylaxis continues to evolve. The incidence of anaphylaxis continues to be difficult to measure. Underreporting due to patients not seeking medical care as well as failure to identify anaphylaxis affects our understanding of the magnitude of the disease. Treatment with intramuscular epinephrine continues to be the recommended first-line therapy, although studies indicate that education of both the patients and the medical community is needed. Adverse food reactions continue to be the leading cause of anaphylaxis presenting for emergency care. Current therapy for food-induced anaphylaxis is built on the foundation of strict dietary avoidance, rapid access to injectable epinephrine, and education to recognize signs and symptoms of anaphylaxis. Investigation into therapy with oral and sublingual immunotherapy as well as other modalities holds hope for improved treatment of food-induced anaphylaxis.
journal_name
Immunol Revjournal_title
Immunological reviewsauthors
Boden SR,Wesley Burks Adoi
10.1111/j.1600-065X.2011.01028.xsubject
Has Abstractpub_date
2011-07-01 00:00:00pages
247-57issue
1eissn
0105-2896issn
1600-065Xjournal_volume
242pub_type
杂志文章,评审abstract：:A detailed analysis of the genes and proteins that participate in the murine immune response to PC has provided key insights at the structural level into the phenomenon of somatic mutation in B cells. Most anti-PC antibodies are encoded by 1 VH gene of the S107 subfamily, and 3 VK genes, VKT15 of the VK22 subfamily, V...
journal_title：Immunological reviews
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journal_title：Immunological reviews
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更新日期：2016-07-01 00:00:00
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更新日期：2009-11-01 00:00:00
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journal_title：Immunological reviews
pub_type： 杂志文章,评审
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更新日期：1989-12-01 00:00:00
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journal_title：Immunological reviews
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更新日期：2000-06-01 00:00:00
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更新日期：2000-02-01 00:00:00
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更新日期：1991-04-01 00:00:00
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更新日期：1990-08-01 00:00:00
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更新日期：2003-10-01 00:00:00
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更新日期：2011-05-01 00:00:00
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更新日期：2004-12-01 00:00:00
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更新日期：2011-11-01 00:00:00
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