Genotyping of Mycobacterium tuberculosis: application in epidemiologic studies.

abstract：:Report from the 28th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2018), Madrid, Spain, 21-24 April 2018 Gram-negative bacteria such as Klebsiella, Acinetobacter and Pseudomonas cause some of the most serious infections and are increasingly resistant to multiple drugs and in some cases, t...

journal_title：Future microbiology

authors： Eckmann C,Rojas LJ,Lyon S

更新日期：2018-10-01 00:00:00

abstract：:West Nile virus (WNV), an emerging mosquito-borne and zoonotic flavivirus, continues to spread worldwide and represents a major problem for human and veterinary medicine. In recent years, severe outbreaks were observed in the USA and Europe with neighboring countries, and the virus is considered to be endemic in an in...

journal_title：Future microbiology

authors： Ulbert S,Magnusson SE

更新日期：2014-01-01 00:00:00

abstract：AIM:To evaluate and characterize the etiopathogenesis of the fusarial onychomycosis in an ex vivo study through fragments of sterile human nail, without the addition of any nutritional source. MATERIALS & METHODS:The infection and invasion of Fusarium oxysporum in the nail were evaluated by scanning electron microscop...

journal_title：Future microbiology

authors： Veiga FF,de Castro-Hoshino LV,Sato F,Bombassaro A,Vicente VA,Mendes V,Baesso ML,Negri M,Svidzinski TI

更新日期：2018-12-01 00:00:00

abstract：:Celebrating its 30th anniversary in Budapest this year, the International Immunocompromised Host Society (ICHS) was established to advance the understanding of interactions between host defenses and microbial agents in order to improve the prevention and management of human disease in patients with compromised immune ...

journal_title：Future microbiology

authors： Maertens J,Bryan J

更新日期：2010-12-01 00:00:00

abstract：AIM:In this study, we investigate whether pH (low) insertion peptide (pHLIP) can target regions of lung injury associated with influenza infection. MATERIALS & METHODS:Fluorophore-conjugated pHLIP was injected intraperitoneally into mice infected with a sublethal dose of H1N1 influenza and visualized histologically. ...

journal_title：Future microbiology

authors： Li N,Yin L,Thévenin D,Yamada Y,Limmon G,Chen J,Chow VT,Engelman DM,Engelward BP

更新日期：2013-02-01 00:00:00

abstract：:Micafungin is a new drug in the echinocandin class and is currently being investigated in Phase III clinical trials. Like other echinocandins, it inhibits 1,3-beta-D-glucan synthesis, thus achieving fungicidal activity against virtually all Candida spp., including those resistant to fluconazole, and fungistatic activi...

journal_title：Future microbiology

authors： Vehreschild JJ,Cornely OA

更新日期：2006-08-01 00:00:00

abstract：AIM:To develop an alternative quorum quenching therapy against multidrug-resistant Acinetobacter baumannii. METHODS & RESULTS:Activity-guided partially purified fraction (F1) from Glycyrrhiza glabra significantly (p < 0.05) reduced quorum sensing regulated virulence factors of A. baumannii viz. motility, biofilm forma...

journal_title：Future microbiology

authors： Bhargava N,Singh SP,Sharma A,Sharma P,Capalash N

更新日期：2015-01-01 00:00:00

abstract：:European Respiratory Society Congress, Amsterdam, 26-30 September 2015, and CHEST 2015, Montréal, Canada, 24-28 October 2015 With approximately 50,000 deaths in the US and EU attributed to antibacterial resistance each year, together with several million days of hospital care [1], the need to address resistance mechan...

journal_title：Future microbiology

authors： Sethi S,Bryan J

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:The seriousness to treat burn wounds infected with Pseudomonas aeruginosa led us to examine whether the effect of the carbapenem antibiotic imipenem is enhanced by hyperbaric oxygen (HBO). MATERIALS & METHODS:The effects of HBO (100% O2, 3 ATA, 5 h) in combination with imipenen on bacterial counts of six is...

journal_title：Future microbiology

authors： Lima FL,Joazeiro PP,Lancellotti M,de Hollanda LM,de Araújo Lima B,Linares E,Augusto O,Brocchi M,Giorgio S

更新日期：2015-01-01 00:00:00

abstract：:Helicobacter pylori is arguably one of the most successful pathogens; it colonizes the stomachs of more than half of the human population. Colonization and persistence in such an inhospitable niche requires the presence of exquisite adaptive mechanisms. One of the proteins that contributes significantly to the remarka...

journal_title：Future microbiology

authors： Pich OQ,Merrell DS

更新日期：2013-06-01 00:00:00

abstract：:The outstanding ability of Acinetobacter baumannii to cause outbreaks and acquire multidrug resistance motivated the development of a plethora of typing techniques, which can help infection preventionists and hospital epidemiologists to more efficiently implement intervention controls. Nowadays, the world is witnessin...

journal_title：Future microbiology

authors： Rafei R,Osman M,Dabboussi F,Hamze M

更新日期：2019-08-01 00:00:00

abstract：:This review focuses on antibodies (Abs) and their function in immune protection, with particular emphasis on microbicidal Abs. Some aspects of Abs and Ab-drug conjugates as targeting therapeutic agents are also discussed. The main aim, however, is devoted to Ab-derived peptides modulating functions of the immune syste...

journal_title：Future microbiology

authors： Magliani W,Giovati L,Ciociola T,Sperindè M,Santinoli C,Conti G,Conti S,Polonelli L

更新日期：2015-01-01 00:00:00

abstract：:Retapamulin is a semisynthetic pleuromutilin compound with in vitroactivity against Gram-positive bacteria, no cross-resistance to other classes of antimicrobial agents in current use and a low potential for development of resistance. A 1% ointment formulation has been developed for clinical use, and a placebo-control...

journal_title：Future microbiology

authors： Jacobs MR

更新日期：2007-12-01 00:00:00

abstract：:Infections with Pseudomonas aeruginosa are a major health problem, especially for immune-compromised and cystic fibrosis patients, owing to the particular drug resistance of the microorganism. The aim of this review is to provide recent insights into strategies under investigation for prevention and therapy of these i...

journal_title：Future microbiology

authors： Savoia D

更新日期：2014-01-01 00:00:00

abstract：:The human periodontium health is commonly compromised by chronic inflammatory conditions and has become a major public health concern. Dental plaque, the precursor of periodontal disease, is a complex biofilm consisting mainly of bacteria, but also archaea, protozoa, fungi and viruses. Viruses that specifically infect...

journal_title：Future microbiology

authors： Pinto G,Silva MD,Peddey M,Sillankorva S,Azeredo J

更新日期：2016-10-01 00:00:00

abstract：:Cryptococcus demonstrates predilection for invasion of the brain, but the mechanism by which Cryptococcus crosses the blood-brain barrier (BBB) to cause brain invasion is largely unknown. In order for Cryptococcus to cross the BBB, there must be a way to either cross human brain microvascular endothelial cells, which ...

journal_title：Future microbiology

authors： Tseng HK,Huang TY,Wu AY,Chen HH,Liu CP,Jong A

更新日期：2015-01-01 00:00:00

abstract：:Antibiotics are often used in neonates despite the absence of relevant dosing information in drug labels. For neonatal dosing, clinicians must extrapolate data from studies for adults and older children, who have strikingly different physiologies. As a result, dosing extrapolation can lead to increased toxicity or eff...

journal_title：Future microbiology

authors： Rivera-Chaparro ND,Cohen-Wolkowiez M,Greenberg RG

更新日期：2017-09-01 00:00:00

abstract：:Traditionally, the patients believed to be at highest risk of invasive aspergillosis (IA) are those who are neutropenic due to chemotherapy for hematological malignancy or those undergoing allogeneic hematopoietic stem cell transplantation. However, emerging data show that other patients are vulnerable to IA, even tho...

journal_title：Future microbiology

authors： Sheppard D,Grist LM

更新日期：2010-07-01 00:00:00

abstract：:Living organisms adapt to the dynamic external environment for their survival. Environmental adaptation in prokaryotes is thought to be primarily accomplished by signaling events mediated by two-component systems, consisting of histidine kinases and response regulators. However, eukaryotic-like serine/threonine kinase...

journal_title：Future microbiology

authors： Burnside K,Rajagopal L

更新日期：2011-07-01 00:00:00

abstract：:Cytomegalovirus (CMV) manifestations remain important complications after allogeneic hematopoietic stem cell transplantation (HSCT), even in the current era. Unfortunately, available anti-CMV agents, mainly viral polymerase inhibitors, have a substantial risk of myelosuppression and nephrotoxicity. Letermovir, a novel...

journal_title：Future microbiology

authors： Hecke SV,Calcoen B,Lagrou K,Maertens J

更新日期：2019-02-01 00:00:00

abstract：:Aim:Cryptococcus neoformans is the major agent of cryptococcosis. The main virulence factor is the polysaccharide (PS) capsule. Changes in cryptococcal PS properties have been poorly elucidated. Materials & methods: We analyzed the mechanical properties of secreted PS and intact capsules, using dynamic light scatterin...

journal_title：Future microbiology

authors： de S Araújo GR,Viana NB,Pontes B,Frases S

更新日期：2019-07-01 00:00:00

abstract：:The inappropriate use of antibiotics has severe global health and economic consequences, including the emergence of antibiotic-resistant bacteria. A major driver of antibiotic misuse is the inability to accurately distinguish between bacterial and viral infections based on currently available diagnostic solutions. A m...

journal_title：Future microbiology

authors： Cohen A,Bont L,Engelhard D,Moore E,Fernández D,Kreisberg-Greenblatt R,Oved K,Eden E,Hays JP

更新日期：2015-01-01 00:00:00

abstract：:Coxiella burnetii is an extremely infectious, zoonotic agent that causes Q fever in humans. With the exception of New Zealand, the bacterium is distributed worldwide. Coxiella is classified as a select agent based on its past and potential use as a bioweapon and its threat to public health. Despite decades of research...

journal_title：Future microbiology

authors： Minnick MF,Raghavan R

更新日期：2011-11-01 00:00:00

abstract：AIM:This study aims to evaluate the genetic and population structure of Vibrio parahaemolyticus in the major coastal regions of China. MATERIALS & METHODS:Multilocus sequence typing was performed. RESULTS:Insertion of large sequence into recA happened in nearly 30 strains, which were untypeable by multilocus sequence...

journal_title：Future microbiology

authors： Li P,Xin W,Kang L,Chen Z,Guo C,Gao S,Yang H,Ji B,Yan Y,Wang H,Zhou D,Yang W,Wang J

更新日期：2018-09-01 00:00:00

abstract：:Eukaryotic proteins are tightly regulated by post-translational modifications, leading to a very subtle degree of regulation in time and space. Pathogen-mediated post-translational modifications are key strategies to modulate host factors by targeting central signaling pathways in the host cell. Legionella pneumophila...

journal_title：Future microbiology

authors： Rolando M,Buchrieser C

更新日期：2012-03-01 00:00:00

abstract：:Cooling towers provide a favorable environment for the proliferation of microorganisms. Cooling towers generate a biofilm and often aerosolize contaminated water, thereby increasing the risk of microorganism dissemination by human inhalation. This pathogen dissemination was first revealed by the epidemics of Legionnai...

journal_title：Future microbiology

authors： Pagnier I,Merchat M,La Scola B

更新日期：2009-06-01 00:00:00

abstract：:Aim: Face masks are an important addition to our arsenal in the fight against COVID-19. The aim of this study is to present a novel method of measuring mask performance which can simultaneously assess both fabric penetration and leakage due to poor fit. Materials & methods: A synthetic aerosol is introduced into the l...

journal_title：Future microbiology

authors： Darby S,Chulliyallipalil K,Przyjalgowski M,McGowan P,Jeffers S,Giltinan A,Lewis L,Smith N,Sleator RD

更新日期：2021-01-01 00:00:00

abstract：:Linda Hazlett is a department chair and distinguished professor at Wayne State University (MI, USA). Her research is focused on the host immune response to Pseudomonas aeruginosa and its role in ocular infections. Dr Hazlett has been funded continuously by the NIH by R01 support for 34 years. She is currently principa...

journal_title：Future microbiology

authors： Hazlett L

更新日期：2013-07-01 00:00:00

abstract：:Helicobacter pylori plays a vital role in the pathogenesis of gastric carcinoma. However, only a relatively small proportion of individuals infected with H. pylori develop gastric carcinoma. Differences in the incidence of gastric carcinoma among infected individuals can be explained, at least partly, by the different...

journal_title：Future microbiology

authors： Wang MY,Liu XF,Gao XZ

更新日期：2015-01-01 00:00:00

abstract：:Traditionally, glycoproteins have been considered the exclusive property of eukaryotes and archaea, but it is now evident that glycoproteins are found in all domains of life. In recent years N-linked glycosylation among some epsilon-proteobacteria has emerged as a new and exciting research area and represents a useful...

journal_title：Future microbiology

authors： Langdon RH,Cuccui J,Wren BW

更新日期：2009-05-01 00:00:00