COVID-19: mask efficacy is dependent on both fabric and fit.


:Aim: Face masks are an important addition to our arsenal in the fight against COVID-19. The aim of this study is to present a novel method of measuring mask performance which can simultaneously assess both fabric penetration and leakage due to poor fit. Materials & methods: A synthetic aerosol is introduced into the lung of a medical dummy. A conical laser sheet surrounds the face of the dummy where it illuminates the aerosol emitted during a simulated breath. The system is demonstrated with five mask types. Conclusions: The curved laser sheet highlights both penetration through the mask fabric and leakage around the edges of the mask. A large variation in both material penetration and leakage was observed.


Future Microbiol


Future microbiology


Darby S,Chulliyallipalil K,Przyjalgowski M,McGowan P,Jeffers S,Giltinan A,Lewis L,Smith N,Sleator RD




Has Abstract


2021-01-01 00:00:00










  • Molecular epidemiology of WU polyomavirus in hospitalized children with acute respiratory tract infection in China.

    abstract:AIM:To explore the molecular epidemiology and clinical characteristics of Washington University polyomavirus (WUPyV) infection in pediatric patients with acute respiratory tract infections in China. MATERIALS & METHODS:A laboratory surveillance was performed to recruit pediatric patients with acute respiratory tract i...

    journal_title:Future microbiology

    pub_type: 杂志文章


    authors: Zhu T,Lu QB,Zhang SY,Wo Y,Zhuang L,Zhang PH,Zhang XA,Wei W,Liu W

    更新日期:2017-05-01 00:00:00

  • Current status and future perspectives on molecular and serological methods in diagnostic mycology.

    abstract::Invasive fungal infections are an important cause of infectious morbidity. Nonculture-based methods are increasingly used for rapid, accurate diagnosis to improve patient outcomes. New and existing DNA amplification platforms have high sensitivity and specificity for direct detection and identification of fungi in cli...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审


    authors: Lau A,Chen S,Sleiman S,Sorrell T

    更新日期:2009-11-01 00:00:00

  • Knowns and unknowns of influenza B viruses.

    abstract::Influenza B viruses (IBVs) circulate annually along with influenza A (IAV) strains during seasonal epidemics. IBV can dominate influenza seasons and cause severe disease, particularly in children and adolescents. Research has revealed interesting aspects of IBV and highlighted the importance of these viruses in clinic...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审


    authors: Koutsakos M,Nguyen TH,Barclay WS,Kedzierska K

    更新日期:2016-01-01 00:00:00

  • Protective host immune responses to Salmonella infection.

    abstract::Salmonella enterica serovars Typhi and Paratyphi are the causative agents of human typhoid fever. Current typhoid vaccines are ineffective and are not widely used in endemic areas. Greater understanding of host-pathogen interactions during Salmonella infection should facilitate the development of improved vaccines to ...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审


    authors: Pham OH,McSorley SJ

    更新日期:2015-01-01 00:00:00

  • Resistance to reverse transcriptase inhibitors used in the treatment and prevention of HIV-1 infection.

    abstract::Inhibitors that target the retroviral enzyme reverse transcriptase (RT) have played an indispensable role in the treatment and prevention of HIV-1 infection. They can be grouped into two distinct therapeutic groups, namely the nucleoside and nucleotide RT inhibitors (NRTIs), and the non-nucleoside RT inhibitors (NNRTI...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审


    authors: Sluis-Cremer N,Wainberg MA,Schinazi RF

    更新日期:2015-01-01 00:00:00

  • Epidemic of surgical-site infections by a single clone of rapidly growing mycobacteria in Brazil.

    abstract:AIM:Our aim is to investigate if the clusters of postsurgical mycobacterial infections, reported between 2004 and 2008 in seven geographically distant states in Brazil, were caused by a single mycobacterial strain. MATERIALS & METHODS:Available information from 929 surgical patients was obtained from local health auth...

    journal_title:Future microbiology

    pub_type: 杂志文章


    authors: Leão SC,Viana-Niero C,Matsumoto CK,Lima KV,Lopes ML,Palaci M,Hadad DJ,Vinhas S,Duarte RS,Lourenço MC,Kipnis A,das Neves ZC,Gabardo BM,Ribeiro MO,Baethgen L,de Assis DB,Madalosso G,Chimara E,Dalcolmo MP

    更新日期:2010-06-01 00:00:00

  • Better than a pound of cure: preventing the development of multidrug-resistant tuberculosis.

    abstract::Diagnostic and treatment delays contribute to increased death and disability among the 490,000 adults and children who develop multidrug-resistant (MDR) tuberculosis every year. Since the treatment of MDR tuberculosis is complex, costly and often toxic, tuberculosis control programs should prioritize strategies to pre...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审


    authors: Byrne AL,Fox GJ,Marais BJ

    更新日期:2018-04-01 00:00:00

  • Safety, tolerability and pharmacokinetics of AFN-1252 administered as immediate release tablets in healthy subjects.

    abstract:AIMS:AFN-1252 is a novel inhibitor of FabI, an essential enzyme in Staphylococcus spp. This study was undertaken to assess the safety, tolerability and pharmacokinetic properties of AFN-1252, following oral administration in an ascending dose trial. MATERIALS & METHODS:This was a double-blind, randomized, placebo-cont...

    journal_title:Future microbiology

    pub_type: 杂志文章,随机对照试验


    authors: Hafkin B,Kaplan N,Hunt TL

    更新日期:2015-01-01 00:00:00

  • How Cryptococcus interacts with the blood-brain barrier.

    abstract::Cryptococcus demonstrates predilection for invasion of the brain, but the mechanism by which Cryptococcus crosses the blood-brain barrier (BBB) to cause brain invasion is largely unknown. In order for Cryptococcus to cross the BBB, there must be a way to either cross human brain microvascular endothelial cells, which ...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审


    authors: Tseng HK,Huang TY,Wu AY,Chen HH,Liu CP,Jong A

    更新日期:2015-01-01 00:00:00

  • 1-benzyl-1,4-diazepane reduces the efflux of resistance-nodulation-cell division pumps in Escherichia coli.

    abstract::Aim: To investigate the action mechanism of 1-benzyl-1,4-diazepane (1-BD) as efflux pump inhibitor (EPI) in Escherichia coli mutants: ΔacrAB or overexpressing AcrAB and AcrEF efflux pumps. Materials & methods: Effect of 1-BD on: antibiotic potentiation, by microdilution method; membrane functionality, by fluorimetric ...

    journal_title:Future microbiology

    pub_type: 杂志文章


    authors: Casalone E,Vignolini T,Braconi L,Gardini L,Capitanio M,Pavone FS,Dei S,Teodori E

    更新日期:2020-07-01 00:00:00

  • Use of the plaque assay for testing the antibiotic susceptibility of intracellular bacteria.

    abstract::The plaque assay was first described for titration of bacterial inoculums and clonal isolation, and was later adapted for testing antibiotics susceptibility and to study virulence factors and motility of bacteria. Over time, the sensitivity and reproducibility of the technique has been improved. Usually, the number of...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审


    authors: Edouard S,Raoult D

    更新日期:2013-10-01 00:00:00

  • Type B coxsackieviruses and their interactions with the innate and adaptive immune systems.

    abstract::Coxsackieviruses are important human pathogens, and their interactions with the innate and adaptive immune systems are of particular interest. Many viruses evade some aspects of the innate response, but coxsackieviruses go a step further by actively inducing, and then exploiting, some features of the host cell respons...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审


    authors: Kemball CC,Alirezaei M,Whitton JL

    更新日期:2010-09-01 00:00:00

  • Nanoscale exploration of microbial surfaces using the atomic force microscope.

    abstract::Atomic force microscopy (AFM) has recently opened a variety of novel possibilities for imaging and manipulating microbial surfaces in their native environment. While AFM imaging offers a means to visualize surface structures at high resolution and in physiological conditions, AFM force spectroscopy enables researchers...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审


    authors: Dufrêne YF

    更新日期:2006-12-01 00:00:00

  • Dual-functioning antimalarials that inhibit the chloroquine-resistance transporter.

    abstract::Malaria remains a major international health challenge. Resistance to a number of existing drugs and evidence of the emergence of artemisinin resistance has emphasized the need for new antimalarials. A new approach has been the preparation of dual-function compounds that include a chloroquine-like antimalarial group a...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审


    authors: Egan TJ,Kuter D

    更新日期:2013-04-01 00:00:00

  • Novel isoniazid derivative as promising antituberculosis agent.

    abstract::Background: A major focus of tuberculosis drug discovery is aimed at the development of novel antibiotics with activity against drug-resistant strains of Mycobacterium tuberculosis. Results: We have synthesized ten isoniazid derivatives and investigated for antibacterial activity toward M. tuberculosis H37Rv and isoni...

    journal_title:Future microbiology

    pub_type: 杂志文章


    authors: Volynets GP,Tukalo MA,Bdzhola VG,Derkach NM,Gumeniuk MI,Tarnavskiy SS,Yarmoluk SM

    更新日期:2020-07-01 00:00:00

  • Direct and indirect effects of the 13-valent pneumococcal conjugate vaccine administered to infants and young children.

    abstract::This paper analyzes the most recent reports regarding the direct and indirect effects of the 13-valent pneumococcal conjugate vaccine (PCV13) when administered to infants and young children. PCV13 extends the protective effects reported for the 7-valent pneumococcal conjugate vaccine (PCV7). A further reduction in the...

    journal_title:Future microbiology

    pub_type: 杂志文章


    authors: Esposito S,Principi N,ESCMID Vaccine Study Group.

    更新日期:2015-01-01 00:00:00

  • Micafungin sodium, the second of the echinocandin class of antifungals: theory and practice.

    abstract::Micafungin is a new drug in the echinocandin class and is currently being investigated in Phase III clinical trials. Like other echinocandins, it inhibits 1,3-beta-D-glucan synthesis, thus achieving fungicidal activity against virtually all Candida spp., including those resistant to fluconazole, and fungistatic activi...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审


    authors: Vehreschild JJ,Cornely OA

    更新日期:2006-08-01 00:00:00

  • Hepatitis E in developed countries: current status and future perspectives.

    abstract::Hepatitis E virus (HEV) was for many years thought to be found almost exclusively in developing countries, where it is a major health issue. Recent studies have shown that HEV causes acute and chronic infection in developed countries. In these geographical settings, HEV is primarily a porcine zoonosis caused by genoty...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审


    authors: Dalton HR,Kamar N,Izopet J

    更新日期:2014-01-01 00:00:00

  • Peptide targeting and imaging of damaged lung tissue in influenza-infected mice.

    abstract:AIM:In this study, we investigate whether pH (low) insertion peptide (pHLIP) can target regions of lung injury associated with influenza infection. MATERIALS & METHODS:Fluorophore-conjugated pHLIP was injected intraperitoneally into mice infected with a sublethal dose of H1N1 influenza and visualized histologically. ...

    journal_title:Future microbiology

    pub_type: 杂志文章


    authors: Li N,Yin L,Thévenin D,Yamada Y,Limmon G,Chen J,Chow VT,Engelman DM,Engelward BP

    更新日期:2013-02-01 00:00:00

  • A multifaceted 'omics' approach for addressing the challenge of antimicrobial resistance.

    abstract::The inappropriate use of antibiotics has severe global health and economic consequences, including the emergence of antibiotic-resistant bacteria. A major driver of antibiotic misuse is the inability to accurately distinguish between bacterial and viral infections based on currently available diagnostic solutions. A m...

    journal_title:Future microbiology

    pub_type: 杂志文章


    authors: Cohen A,Bont L,Engelhard D,Moore E,Fernández D,Kreisberg-Greenblatt R,Oved K,Eden E,Hays JP

    更新日期:2015-01-01 00:00:00

  • Nosocomial Gram-positive antimicrobial susceptibility pattern at a referral teaching hospital in Tehran, Iran.

    abstract:AIMS:The aim of the study was to evaluate epidemiology and susceptibility patterns of nosocomial Gram-positive infections in a referral teaching hospital. METHODS:Over a 1 year period, Gram-positive microorganisms isolated from specimens of hospitalized patients with documented nosocomial infection underwent antimicro...

    journal_title:Future microbiology

    pub_type: 杂志文章


    authors: Soltani R,Khalili H,Abdollahi A,Rasoolinejad M,Dashti-Khavidaki S

    更新日期:2012-07-01 00:00:00

  • Antibiotic-associated diarrhea: epidemiology, trends and treatment.

    abstract::A common complication of antibiotic use is the development of gastrointestinal disease. This complication ranges from mild diarrhea to pseudomembranous colitis. Outbreaks of antibiotic-associated diarrhea (AAD) may also occur in healthcare settings, usually caused by Clostridium difficile. AAD typically occurs in 5-35...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审


    authors: McFarland LV

    更新日期:2008-10-01 00:00:00

  • Rotavirus disease and vaccination: impact on genotype diversity.

    abstract::Temporal and spatial fluctuations in the genotype distribution of human rotaviruses are continuously observed in surveillance studies. New genotypes, such as G9 and G12, have emerged and spread worldwide in a very short time span. In addition, reassortment events have the potential to contribute substantially to genet...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审


    authors: Matthijnssens J,Bilcke J,Ciarlet M,Martella V,Bányai K,Rahman M,Zeller M,Beutels P,Van Damme P,Van Ranst M

    更新日期:2009-12-01 00:00:00

  • Technologies for the development of West Nile virus vaccines.

    abstract::West Nile virus (WNV), an emerging mosquito-borne and zoonotic flavivirus, continues to spread worldwide and represents a major problem for human and veterinary medicine. In recent years, severe outbreaks were observed in the USA and Europe with neighboring countries, and the virus is considered to be endemic in an in...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审


    authors: Ulbert S,Magnusson SE

    更新日期:2014-01-01 00:00:00

  • Emergence of two distinct subpopulations from Klebsiella pneumoniae grown in the stimulated microgravity environment.

    abstract:AIM:To isolate and characterize the two phenotypically distinct subpopulations from Klebsiella pneumoniae clonal cultures grown in the simulate microgravity environment. MATERIALS & METHODS:Here clonal culture of K. pneumoniae strain ATCC BAA-1705 was grown within a vertically rotating wall vessel bioreactor. Microsco...

    journal_title:Future microbiology

    pub_type: 杂志文章


    authors: Wang H,Li W,Gu L,Gao X,Ni B,Deng H,Yang R,Han Y

    更新日期:2017-09-01 00:00:00

  • TUP1-mediated filamentation in Candida albicans leads to inability to colonize the mouse gut.

    abstract:AIM:To investigate the role of Candida albicans TUP1-mediated filamentation in the colonization of the mice gut. MATERIALS & METHODS:We used molecular genetics to generate a strain where filamentation is regulated by altering the expression of the TUP1 gene with tetracyclines. RESULTS:The colonization rates reached w...

    journal_title:Future microbiology

    pub_type: 杂志文章


    authors: Román E,Huertas B,Prieto D,Díez-Orejas R,Pla J

    更新日期:2018-06-01 00:00:00

  • First fungemia case due to environmental yeast Wickerhamomyces myanmarensis: detection by multiplex qPCR and antifungal susceptibility.

    abstract:AIM:Presenting the first clinical case of Wickerhamomyces myanmarensis. PATIENTS & METHODS:Yeast cells were isolated from blood and central venous catheter of a 5.5-year-old male subject. API 20C AUX, MALDI-TOF MS, ITS and LSU rDNA sequencing, and our qPCR assay were used for identification and the MIC values were det...

    journal_title:Future microbiology

    pub_type: 杂志文章


    authors: Arastehfar A,Bakhtiari M,Daneshnia F,Fang W,Sadati SK,Al-Hatmi AM,Groenewald M,Sharifi-Mehr H,Liao W,Pan W,Zomorodian K,Hagen F,Boekhout T

    更新日期:2019-03-01 00:00:00

  • Inhibition of growth and gene expression in Staphylococcus aureus by anti-gyrA peptide nucleic acid.

    abstract::Aim: Multidrug-resistant Staphylococcus aureus isolates have become a serious concern in clinical microbiology. Antisense strategy, which specifically targets essential genes, could be helpful. Materials & methods:S. aureus cultures were treated with peptide conjugate-peptide nucleic acid (PPNA) specific for the gyrA ...

    journal_title:Future microbiology

    pub_type: 杂志文章


    authors: Tavakoli M,Hashemi A,Vaezjalali M,Mohammadzadeh M,Goudarzi H

    更新日期:2019-09-01 00:00:00

  • The ferric uptake regulator of Helicobacter pylori: a critical player in the battle for iron and colonization of the stomach.

    abstract::Helicobacter pylori is arguably one of the most successful pathogens; it colonizes the stomachs of more than half of the human population. Colonization and persistence in such an inhospitable niche requires the presence of exquisite adaptive mechanisms. One of the proteins that contributes significantly to the remarka...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审


    authors: Pich OQ,Merrell DS

    更新日期:2013-06-01 00:00:00

  • Post-translational modifications of host proteins by Legionella pneumophila: a sophisticated survival strategy.

    abstract::Eukaryotic proteins are tightly regulated by post-translational modifications, leading to a very subtle degree of regulation in time and space. Pathogen-mediated post-translational modifications are key strategies to modulate host factors by targeting central signaling pathways in the host cell. Legionella pneumophila...

    journal_title:Future microbiology

    pub_type: 杂志文章,评审


    authors: Rolando M,Buchrieser C

    更新日期:2012-03-01 00:00:00