Prospects for defined epitope vaccines for respiratory syncytial virus.

abstract：:Mycobacterium tuberculosis is included among a select group of bacteria possessing the capacity for de novo biosynthesis of vitamin B12, the largest and most complex natural organometallic cofactor. The bacillus is also able to scavenge B12 and related corrinoids utilizing an ATP-binding cassette-type protein that is ...

journal_title：Future microbiology

authors： Gopinath K,Moosa A,Mizrahi V,Warner DF

更新日期：2013-11-01 00:00:00

abstract：:Aim: To identify intestinal microbiota compositions in elderly functional constipation (FC) patients. Materials & methods: Fecal samples from 61 FC patients and 48 healthy age-matched volunteers were analyzed through 16S rRNA gene sequencing. Results: The intestinal microbiota compositions of FC patients were signific...

journal_title：Future microbiology

authors： Guo M,Yao J,Yang F,Liu W,Bai H,Ma J,Ma X,Zhang J,Fang Y,Miao Y,Sun J,Zhang Y,Zhao H

更新日期：2020-02-01 00:00:00

abstract：:The time is ripe to usher in a new paradigm in infection control and to move beyond our sole reliance on broad-spectrum antibiotics whose use results in extensive collateral damage to our microbiome and, in so doing, exerts significant selective pressures for resistance to emerge. We propose to supplement the existing...

journal_title：Future microbiology

authors： Qiu XQ,Roy SM,Riley MA

更新日期：2015-01-01 00:00:00

abstract：:Retapamulin is a semisynthetic pleuromutilin compound with in vitroactivity against Gram-positive bacteria, no cross-resistance to other classes of antimicrobial agents in current use and a low potential for development of resistance. A 1% ointment formulation has been developed for clinical use, and a placebo-control...

journal_title：Future microbiology

authors： Jacobs MR

更新日期：2007-12-01 00:00:00

abstract：:The plaque assay was first described for titration of bacterial inoculums and clonal isolation, and was later adapted for testing antibiotics susceptibility and to study virulence factors and motility of bacteria. Over time, the sensitivity and reproducibility of the technique has been improved. Usually, the number of...

journal_title：Future microbiology

authors： Edouard S,Raoult D

更新日期：2013-10-01 00:00:00

abstract：AIM:To develop an alternative quorum quenching therapy against multidrug-resistant Acinetobacter baumannii. METHODS & RESULTS:Activity-guided partially purified fraction (F1) from Glycyrrhiza glabra significantly (p < 0.05) reduced quorum sensing regulated virulence factors of A. baumannii viz. motility, biofilm forma...

journal_title：Future microbiology

authors： Bhargava N,Singh SP,Sharma A,Sharma P,Capalash N

更新日期：2015-01-01 00:00:00

abstract：:Influenza B viruses (IBVs) circulate annually along with influenza A (IAV) strains during seasonal epidemics. IBV can dominate influenza seasons and cause severe disease, particularly in children and adolescents. Research has revealed interesting aspects of IBV and highlighted the importance of these viruses in clinic...

journal_title：Future microbiology

authors： Koutsakos M,Nguyen TH,Barclay WS,Kedzierska K

更新日期：2016-01-01 00:00:00

abstract：AIM:Our aim is to investigate if the clusters of postsurgical mycobacterial infections, reported between 2004 and 2008 in seven geographically distant states in Brazil, were caused by a single mycobacterial strain. MATERIALS & METHODS:Available information from 929 surgical patients was obtained from local health auth...

journal_title：Future microbiology

authors： Leão SC,Viana-Niero C,Matsumoto CK,Lima KV,Lopes ML,Palaci M,Hadad DJ,Vinhas S,Duarte RS,Lourenço MC,Kipnis A,das Neves ZC,Gabardo BM,Ribeiro MO,Baethgen L,de Assis DB,Madalosso G,Chimara E,Dalcolmo MP

更新日期：2010-06-01 00:00:00

abstract：:Resistance continues to emerge as a leading cause for antiretroviral treatment failure. Several mutations in HIV reverse transcriptase (RT) confer resistance to non-nucleoside inhibitors (NNRTIs), vital components of antiretroviral combination therapies. Since the majority of mutations are located in the NNRTI binding...

journal_title：Future microbiology

authors： Frey KM

更新日期：2015-01-01 00:00:00

abstract：:Candida albicans, a diploid yeast commensal and opportunist pathogen, has evolved unusual mechanisms for maintenance of genetic diversity in the absence of a complete sexual cycle. These include chromosomal polymorphisms, mitotic recombination events, and gains and losses of heterozygosity, superimposed on a fundament...

journal_title：Future microbiology

authors： Odds FC

更新日期：2010-01-01 00:00:00

abstract：:In this exclusive interview, Simon Gaisford discusses his current research into gut dysbiosis and its possible relevance to disease states, as well as the efficacy of probiotic supplementation and its possible use as treatment. This interview was conducted by Ellen Colvin, Commissioning Editor of Future Microbiology. ...

journal_title：Future microbiology

authors： Gaisford S

更新日期：2019-03-01 00:00:00

abstract：:Invasive fungal infections are an important cause of infectious morbidity. Nonculture-based methods are increasingly used for rapid, accurate diagnosis to improve patient outcomes. New and existing DNA amplification platforms have high sensitivity and specificity for direct detection and identification of fungi in cli...

journal_title：Future microbiology

authors： Lau A,Chen S,Sleiman S,Sorrell T

更新日期：2009-11-01 00:00:00

abstract：:Evaluation of: Kang S-M, Yoo D-G, Lipatov AS et al.: Induction of long-term protective immune responses by influenza H5N1 virus-like particles. PLoS ONE 4, e4667 (2009). This article describes a long-term protective effect of a vaccine candidate against avian influenza H5N1 that is based on A/Viet Nam1203/04 proteins ...

journal_title：Future microbiology

authors： Arnon R,Ben-Yedidia T

更新日期：2009-06-01 00:00:00

abstract：:Aim: To investigate the action mechanism of 1-benzyl-1,4-diazepane (1-BD) as efflux pump inhibitor (EPI) in Escherichia coli mutants: ΔacrAB or overexpressing AcrAB and AcrEF efflux pumps. Materials & methods: Effect of 1-BD on: antibiotic potentiation, by microdilution method; membrane functionality, by fluorimetric ...

journal_title：Future microbiology

authors： Casalone E,Vignolini T,Braconi L,Gardini L,Capitanio M,Pavone FS,Dei S,Teodori E

更新日期：2020-07-01 00:00:00

abstract：:Breastfeeding is a major determinant of human health. Breast milk is not sterile and ecological large-scale sequencing methods have revealed an unsuspected microbial diversity that plays an important role. However, microbiological analysis at the species level has been neglected while it is a prerequisite before under...

journal_title：Future microbiology

authors： Togo A,Dufour JC,Lagier JC,Dubourg G,Raoult D,Million M

更新日期：2019-05-01 00:00:00

abstract：AIMS:Nosocomial infections cause significant morbidity and mortality in cancer patients. As a result of their debilitated immune system, cancer patients are likely candidates for colonization with anaerobes. We sought to compare the distribution of nosocomial infections in neutropenic and non-neutropenic cancer patient...

journal_title：Future microbiology

authors： El-Sharif A,Elkhatib WF,Ashour HM

更新日期：2012-12-01 00:00:00

abstract：AIM:To isolate and characterize the two phenotypically distinct subpopulations from Klebsiella pneumoniae clonal cultures grown in the simulate microgravity environment. MATERIALS & METHODS:Here clonal culture of K. pneumoniae strain ATCC BAA-1705 was grown within a vertically rotating wall vessel bioreactor. Microsco...

journal_title：Future microbiology

authors： Wang H,Li W,Gu L,Gao X,Ni B,Deng H,Yang R,Han Y

更新日期：2017-09-01 00:00:00

abstract：:The Enterococcus species is the third main cause of infective endocarditis (IE) worldwide, and it is gaining relevance, especially among healthcare-associated cases. Patients with enterococcal IE are older and have more comorbidities than other types of IE. Classical treatment options are limited due to the emergence ...

journal_title：Future microbiology

authors： Pericás JM,Zboromyrska Y,Cervera C,Castañeda X,Almela M,Garcia-de-la-Maria C,Mestres C,Falces C,Quintana E,Ninot S,Llopis J,Marco F,Moreno A,Miró JM

更新日期：2015-01-01 00:00:00

abstract：AIM:To quantitatively assess Staphylococcus aureus biofilms. MATERIALS & METHODS:In addition to the qualitative Congo red agar (CRA) method, we used the bioluminescence (BLM), safranine (SAF), crystal violet (CRV) and resazurin (RES) high-throughput microtiter plate-based quantitative assays. RESULTS:60.47% (26/43) o...

journal_title：Future microbiology

authors： Elkhatib WF,Khairalla AS,Ashour HM

更新日期：2014-01-01 00:00:00

abstract：AIM:To explore the molecular epidemiology and clinical characteristics of Washington University polyomavirus (WUPyV) infection in pediatric patients with acute respiratory tract infections in China. MATERIALS & METHODS:A laboratory surveillance was performed to recruit pediatric patients with acute respiratory tract i...

journal_title：Future microbiology

authors： Zhu T,Lu QB,Zhang SY,Wo Y,Zhuang L,Zhang PH,Zhang XA,Wei W,Liu W

更新日期：2017-05-01 00:00:00

abstract：:Aim: In an Emergency Department (ED), the etiological identification of infected subjects is essential. 13 infection-related biomarkers were assessed using a new flow cytometry procedure. Materials & methods: If subjects presented with febrile symptoms at the ED, 13 biomarkers' levels, including CD64 on neutrophils (n...

journal_title：Future microbiology

authors： Bourgoin P,Lediagon G,Arnoux I,Bernot D,Morange PE,Michelet P,Malergue F,Markarian T

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:The seriousness to treat burn wounds infected with Pseudomonas aeruginosa led us to examine whether the effect of the carbapenem antibiotic imipenem is enhanced by hyperbaric oxygen (HBO). MATERIALS & METHODS:The effects of HBO (100% O2, 3 ATA, 5 h) in combination with imipenen on bacterial counts of six is...

journal_title：Future microbiology

authors： Lima FL,Joazeiro PP,Lancellotti M,de Hollanda LM,de Araújo Lima B,Linares E,Augusto O,Brocchi M,Giorgio S

更新日期：2015-01-01 00:00:00

abstract：AIM:To evaluate if radiation used in radiotherapy can cause changes in the virulence potential of Candida tropicalis ATCC 750. MATERIALS & METHODS:C. tropicalis was exposed in vitro to identical dose and scheme of irradiation would be used in patients with head and neck cancer. Some virulence parameters were analyzed ...

journal_title：Future microbiology

authors： da Silva EM,Kischkel B,Shinobu-Mesquita CS,Bonfim-Mendonça PS,Mansano ES,da Silva MA,Barbosa JF,Fiorini A,Hernandes L,Furlaneto MC,Svidzinski TI

更新日期：2017-12-01 00:00:00

abstract：:Salmonella enterica serovars Typhi and Paratyphi are the causative agents of human typhoid fever. Current typhoid vaccines are ineffective and are not widely used in endemic areas. Greater understanding of host-pathogen interactions during Salmonella infection should facilitate the development of improved vaccines to ...

journal_title：Future microbiology

authors： Pham OH,McSorley SJ

更新日期：2015-01-01 00:00:00

abstract：:West Nile virus (WNV), an emerging mosquito-borne and zoonotic flavivirus, continues to spread worldwide and represents a major problem for human and veterinary medicine. In recent years, severe outbreaks were observed in the USA and Europe with neighboring countries, and the virus is considered to be endemic in an in...

journal_title：Future microbiology

authors： Ulbert S,Magnusson SE

更新日期：2014-01-01 00:00:00

abstract：:Oritavancin is a lipoglycopeptide antibiotic with activity against aerobic and anaerobic Gram-positive bacteria. Oritavancin separates itself from other glycopeptides through its potent in vitro activity against resistant isolates of Staphylococcus aureus, Enterococcus spp. and Streptococcus spp. Oritavancin possesses...

journal_title：Future microbiology

authors： Crandon J,Nicolau DP

更新日期：2008-06-01 00:00:00

abstract：:Coxsackieviruses are important human pathogens, and their interactions with the innate and adaptive immune systems are of particular interest. Many viruses evade some aspects of the innate response, but coxsackieviruses go a step further by actively inducing, and then exploiting, some features of the host cell respons...

journal_title：Future microbiology

authors： Kemball CC,Alirezaei M,Whitton JL

更新日期：2010-09-01 00:00:00

abstract：AIM:The effect of astrakurkurone, a novel triterpene, isolated from Indian mushroom Astraeus hygrometricus has been investigated to elucidate the mechanisms involved in selective cell death of Leishmania donovani. MATERIALS & METHODS:The hypotheses were investigated using flow-cytometry, scanning electron microscopy a...

journal_title：Future microbiology

authors： Mallick S,Dey S,Mandal S,Dutta A,Mukherjee D,Biswas G,Chatterjee S,Mallick S,Lai TK,Acharya K,Pal C

更新日期：2015-01-01 00:00:00

abstract：AIM:To characterize the genetic diversity of unrelated Legionella pneumophila clinical isolates in Catalonia and compare with other European regions. METHODS:95 unrelated isolates were analyzed using monoclonal antibodies and sequence-based typing, 1989-2013. RESULTS:The isolates showed a high diversity (IOD 0.964) w...

journal_title：Future microbiology

authors： Garcia-Nuñez M,Quero S,Pedro-Botet ML,Barrabeig I,Avarez J,Campoy I,Sala MR,Parraga-Niño N,Minguell S,Caylà J,Mateu L,Sabria M

更新日期：2016-07-01 00:00:00

abstract：:Infectious disease point-of-care test (ID-POCT) devices are becoming widely available, and in this respect, international quality standards and guidelines are available for consultation once ID-POCT has been implemented into medical institutions. However, specific guidelines for consultation during the initial pre-imp...

journal_title：Future microbiology

authors： van der Eijk AA,Tintu AN,Hays JP

更新日期：2017-01-01 00:00:00