Attenuation of quorum sensing-mediated virulence of Acinetobacter baumannii by Glycyrrhiza glabra flavonoids.

abstract：:Report from the 28th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2018), Madrid, Spain, 21-24 April 2018 Gram-negative bacteria such as Klebsiella, Acinetobacter and Pseudomonas cause some of the most serious infections and are increasingly resistant to multiple drugs and in some cases, t...

journal_title：Future microbiology

authors： Eckmann C,Rojas LJ,Lyon S

更新日期：2018-10-01 00:00:00

abstract：AIM:The purpose of current study is to find out relationship between cas9 gene and antimicrobial resistance in Campylobacter jejuni NCTC11168. MATERIALS & METHODS:The involvement of the cas9 gene in antimicrobial resistance of C. jejuni was determined by assessment of minimum inhibitory concentration, clustered regula...

journal_title：Future microbiology

authors： Shabbir MA,Wu Q,Shabbir MZ,Sajid A,Ahmed S,Sattar A,Tang Y,Li J,Maan MK,Hao H,Yuan Z

更新日期：2018-12-01 00:00:00

abstract：:Most humans are infected with herpes simplex virus (HSV) type 1 in early childhood and remain latently infected throughout life. While most individuals have mild or no symptoms, some will develop destructive HSV keratitis. Ocular infection with HSV-1 and its associated sequelae account for the majority of corneal blin...

journal_title：Future microbiology

authors： Al-Dujaili LJ,Clerkin PP,Clement C,McFerrin HE,Bhattacharjee PS,Varnell ED,Kaufman HE,Hill JM

更新日期：2011-08-01 00:00:00

abstract：AIM:To evaluate if radiation used in radiotherapy can cause changes in the virulence potential of Candida tropicalis ATCC 750. MATERIALS & METHODS:C. tropicalis was exposed in vitro to identical dose and scheme of irradiation would be used in patients with head and neck cancer. Some virulence parameters were analyzed ...

journal_title：Future microbiology

authors： da Silva EM,Kischkel B,Shinobu-Mesquita CS,Bonfim-Mendonça PS,Mansano ES,da Silva MA,Barbosa JF,Fiorini A,Hernandes L,Furlaneto MC,Svidzinski TI

更新日期：2017-12-01 00:00:00

abstract：:During coevolution with their hosts, bacteria have developed functions that allow them to interfere with the mechanisms controlling the proliferation of eukaryotic cells. Cycle inhibiting factor (Cif) is one of these cyclomodulins, the family of bacterial effectors that interfere with the host cell cycle. Acquired ear...

journal_title：Future microbiology

authors： Samba-Louaka A,Taieb F,Nougayrède JP,Oswald E

更新日期：2009-09-01 00:00:00

abstract：AIM:To explore the molecular epidemiology and clinical characteristics of Washington University polyomavirus (WUPyV) infection in pediatric patients with acute respiratory tract infections in China. MATERIALS & METHODS:A laboratory surveillance was performed to recruit pediatric patients with acute respiratory tract i...

journal_title：Future microbiology

authors： Zhu T,Lu QB,Zhang SY,Wo Y,Zhuang L,Zhang PH,Zhang XA,Wei W,Liu W

更新日期：2017-05-01 00:00:00

abstract：:Retapamulin is a semisynthetic pleuromutilin compound with in vitroactivity against Gram-positive bacteria, no cross-resistance to other classes of antimicrobial agents in current use and a low potential for development of resistance. A 1% ointment formulation has been developed for clinical use, and a placebo-control...

journal_title：Future microbiology

authors： Jacobs MR

更新日期：2007-12-01 00:00:00

abstract：:Bacillus anthracis is a Gram-positive, spore-forming bacterium representing the etiological cause of anthrax, a rare lethal disease of animals and humans. Development of anthrax countermeasures has gained increasing attention owing to the potential use of B. anthracis spores as a bioterror weapon. The various forms of...

journal_title：Future microbiology

authors： Chitlaru T,Shafferman A

更新日期：2009-10-01 00:00:00

abstract：AIMS:AFN-1252 is a novel inhibitor of FabI, an essential enzyme in Staphylococcus spp. This study was undertaken to assess the safety, tolerability and pharmacokinetic properties of AFN-1252, following oral administration in an ascending dose trial. MATERIALS & METHODS:This was a double-blind, randomized, placebo-cont...

journal_title：Future microbiology

authors： Hafkin B,Kaplan N,Hunt TL

更新日期：2015-01-01 00:00:00

abstract：AIM:This study aims to evaluate the genetic and population structure of Vibrio parahaemolyticus in the major coastal regions of China. MATERIALS & METHODS:Multilocus sequence typing was performed. RESULTS:Insertion of large sequence into recA happened in nearly 30 strains, which were untypeable by multilocus sequence...

journal_title：Future microbiology

authors： Li P,Xin W,Kang L,Chen Z,Guo C,Gao S,Yang H,Ji B,Yan Y,Wang H,Zhou D,Yang W,Wang J

更新日期：2018-09-01 00:00:00

abstract：:A multidisplay vaccine delivery system has been developed that is nonreplicating and has a protein-based particulate structure. The structure is composed of helical tubules comprising multiple copies of a single nonstructural (NS) protein 1 of bluetongue virus. The helical assemblies present the C terminus of the prot...

journal_title：Future microbiology

authors： Murphy A,Roy P

更新日期：2008-06-01 00:00:00

abstract：:Infections with Pseudomonas aeruginosa are a major health problem, especially for immune-compromised and cystic fibrosis patients, owing to the particular drug resistance of the microorganism. The aim of this review is to provide recent insights into strategies under investigation for prevention and therapy of these i...

journal_title：Future microbiology

authors： Savoia D

更新日期：2014-01-01 00:00:00

abstract：AIM:The effect of astrakurkurone, a novel triterpene, isolated from Indian mushroom Astraeus hygrometricus has been investigated to elucidate the mechanisms involved in selective cell death of Leishmania donovani. MATERIALS & METHODS:The hypotheses were investigated using flow-cytometry, scanning electron microscopy a...

journal_title：Future microbiology

authors： Mallick S,Dey S,Mandal S,Dutta A,Mukherjee D,Biswas G,Chatterjee S,Mallick S,Lai TK,Acharya K,Pal C

更新日期：2015-01-01 00:00:00

abstract：:Aim: To determine the group of compounds from Chrysopogon zizaniodes root essential oil that have antimicrobial activity. Materials & methods: Thin-layer chromatography coupled to direct bioautography was used to determinate the fraction(s) having antimicrobial activity against methicillin-resistant Staphylococcus aur...

journal_title：Future microbiology

authors： Ramírez-Rueda RY,Marinho J,Salvador MJ

更新日期：2019-09-01 00:00:00

abstract：:Influenza B viruses (IBVs) circulate annually along with influenza A (IAV) strains during seasonal epidemics. IBV can dominate influenza seasons and cause severe disease, particularly in children and adolescents. Research has revealed interesting aspects of IBV and highlighted the importance of these viruses in clinic...

journal_title：Future microbiology

authors： Koutsakos M,Nguyen TH,Barclay WS,Kedzierska K

更新日期：2016-01-01 00:00:00

abstract：:Antibiotics are often used in neonates despite the absence of relevant dosing information in drug labels. For neonatal dosing, clinicians must extrapolate data from studies for adults and older children, who have strikingly different physiologies. As a result, dosing extrapolation can lead to increased toxicity or eff...

journal_title：Future microbiology

authors： Rivera-Chaparro ND,Cohen-Wolkowiez M,Greenberg RG

更新日期：2017-09-01 00:00:00

abstract：:The Enterococcus species is the third main cause of infective endocarditis (IE) worldwide, and it is gaining relevance, especially among healthcare-associated cases. Patients with enterococcal IE are older and have more comorbidities than other types of IE. Classical treatment options are limited due to the emergence ...

journal_title：Future microbiology

authors： Pericás JM,Zboromyrska Y,Cervera C,Castañeda X,Almela M,Garcia-de-la-Maria C,Mestres C,Falces C,Quintana E,Ninot S,Llopis J,Marco F,Moreno A,Miró JM

更新日期：2015-01-01 00:00:00

abstract：AIM:To investigate the role of Cat1 overproduction in Candida albicans. MATERIALS & METHODS:Strains overproducing the CAT1 gene were constructed. RESULTS:Cells overproducing CAT1 were found to be more resistant to some oxidants and mammalian phagocytic cells. They also showed reduced intracellular reactive oxygen spe...

journal_title：Future microbiology

authors： Román E,Prieto D,Martin R,Correia I,Mesa Arango AC,Alonso-Monge R,Zaragoza O,Pla J

更新日期：2016-10-01 00:00:00

abstract：:Invasive fungal infections are an important cause of infectious morbidity. Nonculture-based methods are increasingly used for rapid, accurate diagnosis to improve patient outcomes. New and existing DNA amplification platforms have high sensitivity and specificity for direct detection and identification of fungi in cli...

journal_title：Future microbiology

authors： Lau A,Chen S,Sleiman S,Sorrell T

更新日期：2009-11-01 00:00:00

abstract：:Recognition of bacterial infection is the first key step to the initiation of an inflammatory response and host defense. Transmembrane proteins of the Toll-like receptor family have long been recognized as key detectors of the extracellular presence of pathogens. Recently, much research has identified a variety of int...

journal_title：Future microbiology

authors： Evans TJ

更新日期：2009-02-01 00:00:00

abstract：AIM:In this study, we investigate whether pH (low) insertion peptide (pHLIP) can target regions of lung injury associated with influenza infection. MATERIALS & METHODS:Fluorophore-conjugated pHLIP was injected intraperitoneally into mice infected with a sublethal dose of H1N1 influenza and visualized histologically. ...

journal_title：Future microbiology

authors： Li N,Yin L,Thévenin D,Yamada Y,Limmon G,Chen J,Chow VT,Engelman DM,Engelward BP

更新日期：2013-02-01 00:00:00

abstract：:The plaque assay was first described for titration of bacterial inoculums and clonal isolation, and was later adapted for testing antibiotics susceptibility and to study virulence factors and motility of bacteria. Over time, the sensitivity and reproducibility of the technique has been improved. Usually, the number of...

journal_title：Future microbiology

authors： Edouard S,Raoult D

更新日期：2013-10-01 00:00:00

abstract：:Salmonella enterica is an invasive, facultative intracellular gastrointestinal pathogen causing human diseases such as gastroenteritis and typhoid fever. Virulence-attenuated strains of this pathogen have interesting capacities for the generation of live vaccines. Attenuated live typhoidal and nontyphoidal Salmonella ...

journal_title：Future microbiology

authors： Hegazy WA,Hensel M

更新日期：2012-01-01 00:00:00

abstract：:Aim: Multidrug-resistant Staphylococcus aureus isolates have become a serious concern in clinical microbiology. Antisense strategy, which specifically targets essential genes, could be helpful. Materials & methods:S. aureus cultures were treated with peptide conjugate-peptide nucleic acid (PPNA) specific for the gyrA ...

journal_title：Future microbiology

authors： Tavakoli M,Hashemi A,Vaezjalali M,Mohammadzadeh M,Goudarzi H

更新日期：2019-09-01 00:00:00

abstract：:While high-throughput protein-protein interaction screens were first published approximately 10 years ago, systematic attempts to map interactions among viruses and hosts started only a few years ago. HIV-human interactions dominate host-pathogen interaction databases (with approximately 2000 interactions) despite the...

journal_title：Future microbiology

authors： Mendez-Rios J,Uetz P

更新日期：2010-02-01 00:00:00

abstract：:Aim: We sought to investigate the genetic epidemiological relatedness of carbapenem-resistant Acinetobacter baumannii (CRAB) strains of a suspected outbreak in a Lebanese tertiary care hospital to implement necessary infection prevention and control measures. Methods: Twenty-eight nonduplicate CRAB isolates detected a...

journal_title：Future microbiology

authors： Osman M,B Halimeh F,Rafei R,Mallat H,Tom JE,Raad EB,M Diene S,Jamal S,Atrouni AA,Dabboussi F,Moudani W,Madec JY,Saras E,Lupo A,Haenni M,Rolain JM,Hamze M

更新日期：2020-10-01 00:00:00

abstract：:Atomic force microscopy (AFM) has recently opened a variety of novel possibilities for imaging and manipulating microbial surfaces in their native environment. While AFM imaging offers a means to visualize surface structures at high resolution and in physiological conditions, AFM force spectroscopy enables researchers...

journal_title：Future microbiology

authors： Dufrêne YF

更新日期：2006-12-01 00:00:00

abstract：:Breastfeeding is a major determinant of human health. Breast milk is not sterile and ecological large-scale sequencing methods have revealed an unsuspected microbial diversity that plays an important role. However, microbiological analysis at the species level has been neglected while it is a prerequisite before under...

journal_title：Future microbiology

authors： Togo A,Dufour JC,Lagier JC,Dubourg G,Raoult D,Million M

更新日期：2019-05-01 00:00:00

abstract：:Community-acquired pneumonia remains an important cause of disease and death both in the developed and the developing worlds, despite the ready availability of potent antimicrobial agents to which the organisms remain susceptible. Furthermore, disease management is complicated by emerging resistance of the common path...

journal_title：Future microbiology

authors： Feldman C,Anderson R

更新日期：2006-10-01 00:00:00

abstract：:Celebrating its 30th anniversary in Budapest this year, the International Immunocompromised Host Society (ICHS) was established to advance the understanding of interactions between host defenses and microbial agents in order to improve the prevention and management of human disease in patients with compromised immune ...

journal_title：Future microbiology

authors： Maertens J,Bryan J

更新日期：2010-12-01 00:00:00