Abstract:
:This article addresses some of the questions relating to how hepatitis delta virus (HDV), an agent so far unique in the animal world, might have arisen. HDV was discovered in patients infected with hepatitis B virus (HBV). It generally makes HBV infections more damaging to the liver. It is a subviral satellite agent that depends upon HBV envelope proteins for its assembly and ability to infect new cells. In other aspects of replication, HDV is both independent of and very different from HBV. In addition, the small single-stranded circular RNA genome of HDV, and its mechanism of replication, demonstrate an increasing number of similarities to the viroids - a large family of helper-independent subviral agents that cause pathogenesis in plants.
journal_name
Future Microbioljournal_title
Future microbiologyauthors
Taylor J,Pelchat Mdoi
10.2217/fmb.10.15subject
Has Abstractpub_date
2010-03-01 00:00:00pages
393-402issue
3eissn
1746-0913issn
1746-0921journal_volume
5pub_type
杂志文章,评审abstract:AIM:To develop an alternative quorum quenching therapy against multidrug-resistant Acinetobacter baumannii. METHODS & RESULTS:Activity-guided partially purified fraction (F1) from Glycyrrhiza glabra significantly (p < 0.05) reduced quorum sensing regulated virulence factors of A. baumannii viz. motility, biofilm forma...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb.15.107
更新日期:2015-01-01 00:00:00
abstract:AIM:Our aim is to investigate if the clusters of postsurgical mycobacterial infections, reported between 2004 and 2008 in seven geographically distant states in Brazil, were caused by a single mycobacterial strain. MATERIALS & METHODS:Available information from 929 surgical patients was obtained from local health auth...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb.10.49
更新日期:2010-06-01 00:00:00
abstract::Influenza B viruses (IBVs) circulate annually along with influenza A (IAV) strains during seasonal epidemics. IBV can dominate influenza seasons and cause severe disease, particularly in children and adolescents. Research has revealed interesting aspects of IBV and highlighted the importance of these viruses in clinic...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.15.120
更新日期:2016-01-01 00:00:00
abstract::Currently, there is growing interest in the identification and purification of microbial lectins due to their involvement in the pathogenicity mechanisms of pathogens, such as Entamoeba histolytica and free-living amoebae. The Gal/GalNAc lectin from E. histolytica participates in adhesion, cytotoxicity and regulation ...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2019-0275
更新日期:2020-07-01 00:00:00
abstract::Staphylococcus aureus is a major human pathogen responsible for a wide diversity of infections ranging from localized to life threatening diseases. From 1961 and the emergence of methicillin-resistant S. aureus (MRSA), this bacterium has shown a particular capacity to survive and adapt to drastic environmental changes...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb.11.38
更新日期:2011-05-01 00:00:00
abstract::While high-throughput protein-protein interaction screens were first published approximately 10 years ago, systematic attempts to map interactions among viruses and hosts started only a few years ago. HIV-human interactions dominate host-pathogen interaction databases (with approximately 2000 interactions) despite the...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.10.7
更新日期:2010-02-01 00:00:00
abstract::Aim: To investigate the action mechanism of 1-benzyl-1,4-diazepane (1-BD) as efflux pump inhibitor (EPI) in Escherichia coli mutants: ΔacrAB or overexpressing AcrAB and AcrEF efflux pumps. Materials & methods: Effect of 1-BD on: antibiotic potentiation, by microdilution method; membrane functionality, by fluorimetric ...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2019-0296
更新日期:2020-07-01 00:00:00
abstract::Invasive fungal infections are an important cause of infectious morbidity. Nonculture-based methods are increasingly used for rapid, accurate diagnosis to improve patient outcomes. New and existing DNA amplification platforms have high sensitivity and specificity for direct detection and identification of fungi in cli...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.09.70
更新日期:2009-11-01 00:00:00
abstract::A common complication of antibiotic use is the development of gastrointestinal disease. This complication ranges from mild diarrhea to pseudomembranous colitis. Outbreaks of antibiotic-associated diarrhea (AAD) may also occur in healthcare settings, usually caused by Clostridium difficile. AAD typically occurs in 5-35...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/17460913.3.5.563
更新日期:2008-10-01 00:00:00
abstract:AIM:Raman spectroscopy is an analytical method with a broad range of applications across multiple scientific fields. We report on a possibility to differentiate between two important Gram-positive species commonly found in clinical material - Staphylococcus aureus and Staphylococcus epidermidis - using this rapid nonin...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2016-0224
更新日期:2017-08-01 00:00:00
abstract:AIM:Glutaredoxin is a conserved oxidoreductase in eukaryotes and prokaryotes. This study aimed to determine the role of Grx3 in cell survival, iron homeostasis and the oxidative stress response in Candida albicans. MATERIALS & METHODS:A grx3Δ/Δ mutant was obtained using PCR-mediated homologs recombination. The functio...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2017-0098
更新日期:2017-11-01 00:00:00
abstract::Genotyping is used to track specific isolates of Mycobacterium tuberculosis in a community. It has been successfully used in epidemiologic research (termed 'molecular epidemiology') to study the transmission dynamics of TB. In this article, we review the genetic markers used in molecular epidemiologic studies includin...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.10.165
更新日期:2011-02-01 00:00:00
abstract::The inappropriate use of antibiotics has severe global health and economic consequences, including the emergence of antibiotic-resistant bacteria. A major driver of antibiotic misuse is the inability to accurately distinguish between bacterial and viral infections based on currently available diagnostic solutions. A m...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb.14.127
更新日期:2015-01-01 00:00:00
abstract::Chlamydial infections cause a wide range of acute and chronic diseases. Chlamydia trachomatis is the most common sexually transmitted bacterium while Chlamydia pneumoniae causes infections of the upper and lower respiratory tract. Chlamydia are obligate, intracellular bacteria with a biphasic developmental cycle that ...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.14.13
更新日期:2014-01-01 00:00:00
abstract::Traditionally, the patients believed to be at highest risk of invasive aspergillosis (IA) are those who are neutropenic due to chemotherapy for hematological malignancy or those undergoing allogeneic hematopoietic stem cell transplantation. However, emerging data show that other patients are vulnerable to IA, even tho...
journal_title:Future microbiology
pub_type:
doi:10.2217/fmb.10.73
更新日期:2010-07-01 00:00:00
abstract::Aim: Face masks are an important addition to our arsenal in the fight against COVID-19. The aim of this study is to present a novel method of measuring mask performance which can simultaneously assess both fabric penetration and leakage due to poor fit. Materials & methods: A synthetic aerosol is introduced into the l...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2020-0292
更新日期:2021-01-01 00:00:00
abstract::Aim: We sought to investigate the genetic epidemiological relatedness of carbapenem-resistant Acinetobacter baumannii (CRAB) strains of a suspected outbreak in a Lebanese tertiary care hospital to implement necessary infection prevention and control measures. Methods: Twenty-eight nonduplicate CRAB isolates detected a...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2020-0079
更新日期:2020-10-01 00:00:00
abstract:AIM:To compare two identification methods for coagulase-negative staphylococci (CoNS) isolated from patients with urinary tract infections, VITEK® 2 and MALDI-TOF VITEK®MS, with genotypic identification by internal transcribed spacer PCR (ITS-PCR). RESULTS:A total of 217 CoNS isolates were studied. Agreement of the VI...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2018-0195
更新日期:2018-11-01 00:00:00
abstract::Recognition of bacterial infection is the first key step to the initiation of an inflammatory response and host defense. Transmembrane proteins of the Toll-like receptor family have long been recognized as key detectors of the extracellular presence of pathogens. Recently, much research has identified a variety of int...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/17460913.4.1.65
更新日期:2009-02-01 00:00:00
abstract::Helicobacter pylori is arguably one of the most successful pathogens; it colonizes the stomachs of more than half of the human population. Colonization and persistence in such an inhospitable niche requires the presence of exquisite adaptive mechanisms. One of the proteins that contributes significantly to the remarka...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.13.43
更新日期:2013-06-01 00:00:00
abstract::Diagnostic and treatment delays contribute to increased death and disability among the 490,000 adults and children who develop multidrug-resistant (MDR) tuberculosis every year. Since the treatment of MDR tuberculosis is complex, costly and often toxic, tuberculosis control programs should prioritize strategies to pre...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb-2017-0236
更新日期:2018-04-01 00:00:00
abstract:AIMS:The aim of the study was to evaluate epidemiology and susceptibility patterns of nosocomial Gram-positive infections in a referral teaching hospital. METHODS:Over a 1 year period, Gram-positive microorganisms isolated from specimens of hospitalized patients with documented nosocomial infection underwent antimicro...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb.12.51
更新日期:2012-07-01 00:00:00
abstract:AIMS:Glucuronoxylomannan (GXM) is the major polysaccharide component of Cryptococcus neoformans. We evaluated in this study whether GXM fractions of different molecular masses were functionally distinct. MATERIALS & METHODS:GXM samples isolated from C. neoformans cultures were fractionated to generate polysaccharide p...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb.13.163
更新日期:2014-01-01 00:00:00
abstract::Background: There is increasing evidence of the association between microbiome dysfunction and Parkinson's disease (PD). Moreover, some PD patients suffer from unintentional weight loss (WL) which may precede the motor manifestations of the disease. Materials & methods: Gut microbiota profiling by 16S rRNA gene sequen...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2019-0336
更新日期:2020-09-01 00:00:00
abstract::Aim:Helicobacter pylori is usually detected based on hematoxylin-eosin (H-E) features, but, immunohistochemistry (IHC) and real-time PCR (RT-PCR) are more precise in chronic-gastritis. We evaluated the relevance of these tests in Peruvian gastric cancer samples. Materials & methods: We performed and evaluated H-E, IHC...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2019-0280
更新日期:2020-08-01 00:00:00
abstract:AIM:The primary objective of this study was to evaluate correlations among mortality, intensive care unit (ICU) length of stay and airway microbiotas in septic patients. MATERIALS & METHODS:A deep-sequencing analysis of the 16S rRNA gene V4 region was performed. RESULTS:The nasal microbiota in septic patients was dom...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2018-0349
更新日期:2019-03-01 00:00:00
abstract::Evaluation of: Kang S-M, Yoo D-G, Lipatov AS et al.: Induction of long-term protective immune responses by influenza H5N1 virus-like particles. PLoS ONE 4, e4667 (2009). This article describes a long-term protective effect of a vaccine candidate against avian influenza H5N1 that is based on A/Viet Nam1203/04 proteins ...
journal_title:Future microbiology
pub_type: 评论,杂志文章
doi:10.2217/fmb.09.33
更新日期:2009-06-01 00:00:00
abstract:AIM:To investigate the collective resistance of the bacteria population with resistant horizontal gene transfer under sublethal bactericide pressure. MATERIALS & METHODS:By employing qualitative analysis of ordinary differential equations, particularly bifurcation theory and several numerical simulations, a modified 4...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2017-0070
更新日期:2018-02-01 00:00:00
abstract::Living organisms adapt to the dynamic external environment for their survival. Environmental adaptation in prokaryotes is thought to be primarily accomplished by signaling events mediated by two-component systems, consisting of histidine kinases and response regulators. However, eukaryotic-like serine/threonine kinase...
journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.11.62
更新日期:2011-07-01 00:00:00
abstract::Aim: The purpose of this study was to evaluate the antifungal activity of midazolam, alone and in association with azoles, against isolates of clinical Candida spp. in planktonic and biofilm form. Materials & methods: The antifungal activity was observed using the broth microdilution technique. Flow cytometry tests we...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb-2020-0080
更新日期:2021-01-01 00:00:00