Abstract:
AIM:Our aim is to investigate if the clusters of postsurgical mycobacterial infections, reported between 2004 and 2008 in seven geographically distant states in Brazil, were caused by a single mycobacterial strain. MATERIALS & METHODS:Available information from 929 surgical patients was obtained from local health authorities. A total of 152 isolates from surgical patients were identified by PCR restriction enzyme analysis of the hsp65 gene (PRA-hsp65) and sequencing of the rpoB gene. Isolates were typed by pulsed-field gel electrophoresis (PFGE) using two restriction enzymes, DraI and AseI. A total of 15 isolates not related to surgical cases were analyzed for comparison. RESULTS:All isolates were identified as Mycobacterium abscessus ssp. massiliense. Isolates from surgical patients and one sputum isolate grouped in a single PFGE cluster, composed of two closely related patterns, with one band difference. A total of 14 other isolates unrelated to surgical cases showed distinctive PFGE patterns. CONCLUSION:A particular strain of M. abscessus ssp. massiliense was associated with a prolonged epidemic of postsurgical infections in seven Brazilian states, suggesting that this strain may be distributed in Brazilian territory and better adapted to cause surgical-site infections.
journal_name
Future Microbioljournal_title
Future microbiologyauthors
Leão SC,Viana-Niero C,Matsumoto CK,Lima KV,Lopes ML,Palaci M,Hadad DJ,Vinhas S,Duarte RS,Lourenço MC,Kipnis A,das Neves ZC,Gabardo BM,Ribeiro MO,Baethgen L,de Assis DB,Madalosso G,Chimara E,Dalcolmo MPdoi
10.2217/fmb.10.49subject
Has Abstractpub_date
2010-06-01 00:00:00pages
971-80issue
6eissn
1746-0913issn
1746-0921journal_volume
5pub_type
杂志文章abstract::Mycobacterium tuberculosis, the agent of TB, is a facultative intracellular bacterial pathogen that replicates inside host macrophages and other phagocytes within a membrane-bound vacuole or phagosome. How M. tuberculosis captures and exploits vital nutrients inside host cells is an intensive research area that might ...
journal_title:Future microbiology
pub_type: 杂志文章
doi:10.2217/fmb.14.28
更新日期:2014-01-01 00:00:00
abstract::Evaluation of: Belogurov GA, Vassylyeva MN, Sevostyanova A et al.: Transcription inactivation through local refolding of the RNA polymerase structure. Nature 457, 332-335 (2008) and, Mukhopadhyay J, Das K, Ismail S et al.: The RNA polymerase 'switch region' is a target for inhibitors. Cell 135, 295-307 (2008). Bacteri...
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pub_type: 杂志文章,随机对照试验
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abstract:AIM:The primary objective of this study was to evaluate correlations among mortality, intensive care unit (ICU) length of stay and airway microbiotas in septic patients. MATERIALS & METHODS:A deep-sequencing analysis of the 16S rRNA gene V4 region was performed. RESULTS:The nasal microbiota in septic patients was dom...
journal_title:Future microbiology
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abstract:AIMS:We explored changes in antibiotic susceptibility of Serratia marcescens in the last 50 years by comparing isolates collected between 1945 and 1950, and current isolates. MATERIALS & METHODS:Isolates were divided into three groups: environmental, clinical and 'old'. Susceptibility was determined by microdilution. ...
journal_title:Future microbiology
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更新日期:2010-11-01 00:00:00
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journal_title:Future microbiology
pub_type: 杂志文章
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journal_title:Future microbiology
pub_type: 评论,杂志文章
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更新日期:2009-06-01 00:00:00
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journal_title:Future microbiology
pub_type: 杂志文章
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更新日期:2019-07-01 00:00:00
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pub_type: 面试
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更新日期:2019-03-01 00:00:00
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journal_title:Future microbiology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
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更新日期:2018-08-01 00:00:00
abstract::Linda Hazlett is a department chair and distinguished professor at Wayne State University (MI, USA). Her research is focused on the host immune response to Pseudomonas aeruginosa and its role in ocular infections. Dr Hazlett has been funded continuously by the NIH by R01 support for 34 years. She is currently principa...
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pub_type: 面试
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更新日期:2013-07-01 00:00:00
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更新日期:2015-01-01 00:00:00
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pub_type: 临床试验,杂志文章
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更新日期:2021-01-01 00:00:00
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更新日期:2012-12-01 00:00:00
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更新日期:2013-11-01 00:00:00
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更新日期:2015-01-01 00:00:00
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pub_type: 杂志文章
doi:10.2217/fmb.12.51
更新日期:2012-07-01 00:00:00
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更新日期:2012-02-01 00:00:00
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更新日期:2014-01-01 00:00:00
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更新日期:2014-01-01 00:00:00