New insights into Prevotella diversity and medical microbiology.

Abstract:

:In light of recent studies based on cultivation-independent methods, it appears that the diversity of Prevotella in human microbiota is greater than was previously assumed from cultivation-based studies, and that the implication of these bacteria in several human diseases was unrecognized. While some Prevotella taxa were found during opportunistic infections, changes in Prevotella abundance and diversity were discovered during dysbiosis-associated diseases. As member of the microbiota, Prevotella may also be considered as a reservoir for resistance genes. Greater knowledge on Prevotella diversity, as well as new insights into its pathogenic potential and implication in dysbiosis are expected from the use of human microbe identification microarrays, from whole-genome sequence analyse, and from the NIH Human Microbiome Project data. New approaches, including molecular-based methods, could contribute to improve the diagnosis of Prevotella infections.

journal_name

Future Microbiol

journal_title

Future microbiology

authors

Alauzet C,Marchandin H,Lozniewski A

doi

10.2217/fmb.10.126

subject

Has Abstract

pub_date

2010-11-01 00:00:00

pages

1695-718

issue

11

eissn

1746-0913

issn

1746-0921

journal_volume

5

pub_type

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