Abstract:
AIM:The primary objective of this study was to evaluate correlations among mortality, intensive care unit (ICU) length of stay and airway microbiotas in septic patients. MATERIALS & METHODS:A deep-sequencing analysis of the 16S rRNA gene V4 region was performed. RESULTS:The nasal microbiota in septic patients was dominated by three nasal bacterial types (Corynebacterium, Staphylococcus and Acinetobacter). The Acinetobacter type was associated with the lowest diversity and longest length of stay (median: 9 days), and the Corynebacterium type was associated with the shortest length of stay. We found that the Acinetobacter type in the >9-day group was associated with the highest mortality (33%). CONCLUSION:Septic patients have three nasal microbiota types, and the nasal microbiota is related to the length of stay and mortality.
journal_name
Future Microbioljournal_title
Future microbiologyauthors
Tan XL,Liu HY,Long J,Jiang Z,Luo Y,Zhao X,Cai S,Zhong X,Cen Z,Su J,Zhou Hdoi
10.2217/fmb-2018-0349subject
Has Abstractpub_date
2019-03-01 00:00:00pages
383-395eissn
1746-0913issn
1746-0921journal_volume
14pub_type
杂志文章abstract::Malaria remains a major international health challenge. Resistance to a number of existing drugs and evidence of the emergence of artemisinin resistance has emphasized the need for new antimalarials. A new approach has been the preparation of dual-function compounds that include a chloroquine-like antimalarial group a...
journal_title:Future microbiology
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journal_title:Future microbiology
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journal_title:Future microbiology
pub_type: 杂志文章,多中心研究
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更新日期:2016-01-01 00:00:00
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更新日期:2016-01-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.2217/fmb.14.98
更新日期:2015-01-01 00:00:00
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pub_type: 杂志文章
doi:10.2217/fmb-2017-0058
更新日期:2017-09-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.2217/fmb.09.60
更新日期:2009-09-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2015-01-01 00:00:00
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pub_type: 杂志文章
doi:10.2217/fmb.14.111
更新日期:2015-01-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2015-01-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2017-07-01 00:00:00
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journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.09.73
更新日期:2009-10-01 00:00:00
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journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.10.7
更新日期:2010-02-01 00:00:00
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journal_title:Future microbiology
pub_type:
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更新日期:2010-07-01 00:00:00
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journal_title:Future microbiology
pub_type: 杂志文章,评审
doi:10.2217/fmb.11.144
更新日期:2012-01-01 00:00:00