Abstract:
:The aim of this study was to compare the short-term performance of a session of single photodynamic therapy (PDT) and of a conventional ultrasonic debridement (UST) in persistent pockets of maintenance patients. In a prospective, randomized, controlled, single-blind clinical study, patients with chronic periodontitis with at least two persistent pockets (>4 mm) were enrolled. They were treated either with UST (n = 29) or PDT (n = 25). Clinical and microbiological examinations were performed at baseline and after 3 months. For UST, the mean probing depth was reduced from 5.3 to 4.5 mm (p = <0.001) and for PDT from 5.3 to 4.7 mm (p < 0.001) with no difference between the two treatment modalities. Microbial counts were significantly reduced about 30% to 40% immediately after debridement but returned to baseline values a 3 months irrespective of treatment. PDT is not superior to conventional mechanical treatment of persistent pockets, but it may be a meaningful therapeutic alternative; the clinical effects were too minor to draw a definitive conclusion.
journal_name
Clin Oral Investigjournal_title
Clinical oral investigationsauthors
Rühling A,Fanghänel J,Houshmand M,Kuhr A,Meisel P,Schwahn C,Kocher Tdoi
10.1007/s00784-009-0347-4subject
Has Abstractpub_date
2010-12-01 00:00:00pages
637-44issue
6eissn
1432-6981issn
1436-3771journal_volume
14pub_type
杂志文章,随机对照试验abstract::This study deals with 4971 implants (Brånemark system) installed in 1315 patients, either fully or partially edentulous, and followed from implant installation up to the last control. A predominance of female patients (61%) and a nearly equal number of upper and lower jaws characterised the study group. Patients were ...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s007840050107
更新日期:2000-03-01 00:00:00
abstract:OBJECTIVES:The purpose of this study was to investigate whether the genetic variations which could regulate inflammatory responses were associated with the risk of peri-implantitis. MATERIALS AND METHODS:We evaluated three genetic variants including tumor necrosis factor-alpha (TNF-α) - 308G/A, interleukin-1 alpha (IL...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-019-02968-z
更新日期:2020-02-01 00:00:00
abstract::The translucency of teeth allows the non-destructive subsurface visualisation of their microstructure by confocal laser scanning microscopy (CLSM) at a level of about 150 microns below the surface. The dentine-enamel junction (DEJ) is accessible only directly adjacent to the cervix of the tooth. Therefore teeth have t...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s007840050038
更新日期:1998-03-01 00:00:00
abstract::Optimizing the quality of tooth-colored restorations is one of the main topics of current research. But there is only little information available about university education in this field. The aim of this study was to collect and evaluate data about the different aspects of dental education in Germany concerning tooth...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s007840050075
更新日期:1999-03-01 00:00:00
abstract:BACKGROUND:Cleft lip and palate (CLP) represents the most common malformation of the midfacial region worldwide. It can be suggested that the facial stigmatization, the speech impediment, and the long-standing pressure of treatment cause a range of life stressors. Neurocortical information is influenced by physiologica...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-015-1465-9
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVES:It is well accepted that stage-specific embryonic antigen (SSEA)-4 is an antigen that is useful to isolate adult stem cells analogous to embryonic stem cells. Therefore, in the present study, we investigated whether SSEA-4 can also be used as a marker to identify human deciduous dental pulp (D-DP) stem cells...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-014-1260-z
更新日期:2015-03-01 00:00:00
abstract::At a dental office in Münster, Germany, the majority of gold inlays incorporated between July 1969 and August 1999 (n=2,071) in 531 patients were checked with reference to the dental records and assessed retrospectively to determine their longevity. One hundred seventy-five gold inlays were rated as failures (no longe...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s007840100119
更新日期:2001-09-01 00:00:00
abstract::Opisthorchis viverrini (O. viverrini; known as human liver fluke) is a major health problem in the northeastern region of Thailand. Infection with O. viverrini is the cause of hepatobiliary disease and cholangiocarcinoma (CCA). Previous studies demonstrated specific antibodies to crude O. viverrini antigens in serum f...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-010-0421-y
更新日期:2011-08-01 00:00:00
abstract:OBJECTIVE:SLC22A4/5 single nucleotide polymorphisms (SNPs) have been reported to affect inflammatory diseases. We report the relationship of these polymorphisms with adiposity and tooth loss as elucidated in a 10-year follow-up study. METHODS:Participants of the Study of Health in Pomerania (SHIP, N = 4105) were genot...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03594-w
更新日期:2021-02-01 00:00:00
abstract::Previous work showed that a single application of 40% chlorhexidine varnish, EC40, reduced plaque acidogenicity upon sucrose challenge during less than 3 weeks. It was questioned whether lactic acid production could be reduced significantly longer when the treatment was intensified. Therefore, the effects of three con...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-006-0079-7
更新日期:2007-03-01 00:00:00
abstract:OBJECTIVES:There is an increasing number of oral squamous cell carcinoma (OSCC) associated with HPV-16. However, p16 expression by immunohistochemistry as the current gold standard for a surrogate marker for virus infection reveals unsatisfying diagnostic accuracy. The aim of this study was to investigate a new rapid t...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03601-0
更新日期:2020-10-23 00:00:00
abstract:OBJECTIVES:The study evaluates the influence of two spacer settings and three resin luting materials on the marginal and internal fit of polymer-infiltrated ceramic network (PICN) material crowns manufactured using a complete digital workflow. METHODS:Optical impressions of fifty identical dies were performed using th...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-019-03053-1
更新日期:2020-06-01 00:00:00
abstract:OBJECTIVES:Stud attachments are often too adhesive and too susceptible to damage for use in geriatric patients, especially when implants are angulated. This study aimed to evaluate alternative anchoring systems comprising individual and prefabricated polyvinylsiloxane (PVS) attachments. MATERIALS AND METHODS:A total o...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-018-2568-x
更新日期:2019-03-01 00:00:00
abstract:OBJECTIVES:To analyze the potential of human dental pulp stem cells (hDPSCs) for maintaining their undifferentiated status and osteogenic differentiation capacity when arranged in cell sheets (CSs) for future application in bone replacement. MATERIALS AND METHODS:CSs were formed after being induced for 10-15 days by c...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-018-2630-8
更新日期:2019-06-01 00:00:00
abstract:OBJECTIVES:Recent scientific evidences suggest a relevant role of the oral cavity in the transmission and pathogenicity of SARS-CoV-2. METHODS:A literature search was performed in PubMed, up to April 30, 2020, focusing on SARS-CoV-2, COVID-19, oral cavity, and antimicrobial agents. RESULTS:Oral viral load of SARS-CoV...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03413-2
更新日期:2020-08-01 00:00:00
abstract::The present study focuses on the correlation between the expression pattern of β-catenin (component of Wnt signaling), ΔNp63 (proliferation marker), and Notch 1 (transmembrane receptor) in oral squamous cell carcinoma. The study also aims to investigate the interaction between β-catenin and ΔNp63 in oral cancer. Furth...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-011-0605-0
更新日期:2012-08-01 00:00:00
abstract:OBJECTIVES:This in vitro study evaluated the effect of fiber insertion depth on antimicrobial efficacy of antimicrobial photodynamic therapy (aPDT) using a photosensitizer (PS; toluidine blue) and a red light-emitting diode (LED) in root canals infected with Enterococcus faecalis. MATERIALS AND METHODS:Single-rooted e...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-016-1948-3
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVES:Platelet-rich plasma has been used in the treatment of extraction socket; however, randomized controlled clinical trial is still lacking to evaluate its effect on extraction socket healing. MATERIALS AND METHODS:Single center, assessor-blinded, parallel group, randomized controlled clinical trial was conduc...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-014-1278-2
更新日期:2015-04-01 00:00:00
abstract:OBJECTIVES:To evaluate the prevalence, clinical features, and risk factors of dentin hypersensitivity (DH) in a Brazilian population. MATERIALS AND METHODS:300 patients at the Dentistry Clinic of the University of São Paulo participated in this study. The subjects completed a questionnaire regarding their personal inf...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-013-1008-1
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVES:Emdogain, containing an extract of fetal porcine enamel matrix proteins, is a potent stimulator of in vitro osteoclastogenesis. The underlying molecular mechanisms are, however, unclear. MATERIAL AND METHODS:Here, we have addressed the role of transforming growth factor-beta receptor type 1 (TGF-βRI) kinase...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-013-1129-6
更新日期:2014-07-01 00:00:00
abstract:OBJECTIVE:To establish the association between adipokine levels and markers of periodontal involvement as risk indicators of early stages of RA (eRA) and the interaction between the presence of markers of periodontal disease with adipokine in eRA individuals. MATERIALS AND METHODS:Fifty-one patients with a diagnosis o...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03469-0
更新日期:2020-08-01 00:00:00
abstract:OBJECTIVES:The aim of the present study was the qualitative and quantitative evaluation of osseous graft consolidation using allogeneic bone blocks for vertical bone augmentation in an animal model. MATERIAL AND METHODS:Standardised allogeneic and autologous bone blocks were fixed on the frontal skull of 20 adult fema...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-019-03151-0
更新日期:2020-08-01 00:00:00
abstract::This study evaluated the colour parameters of composite and ceramic shade guides determined using a colorimeter and digital imaging method with illuminants at different colour temperatures. Two different resin composite shade guides, namely Charisma (Heraeus Kulzer) and Premise (Kerr Corporation), and two different ce...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-009-0329-6
更新日期:2010-12-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate the acidogenicity of dual-species biofilms of bifidobacteria and Streptococcus mutans. MATERIALS AND METHODS:The following strains were tested: Bifidobacterium dentium DSM20436, Parascardovia denticolens DSM10105, and Scardovia inopinata DSM10107. Streptococcus mutans UA...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-016-1958-1
更新日期:2017-06-01 00:00:00
abstract::The effect of fluoride released by bioadhesive tablets was evaluated in an in situ model in human volunteers. Eight volunteers carried four to six polished human enamel samples in a lower lingual device for a period of 5 days without fluoride supplements (control) and 5 days using one bioadhesive tablet (0.5 mg F) per...
journal_title:Clinical oral investigations
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s007840000076
更新日期:2000-09-01 00:00:00
abstract:OBJECTIVES:The aim of this retrospective cephalometric study was to compare treatment outcomes with "bite jumping appliance" (BJA) or Andresen-Häupl type activator. It especially focused on skeletal and dental structures in patients with class II malocclusion. The study hypothesis was that differences in treatment-rela...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-019-03115-4
更新日期:2020-07-01 00:00:00
abstract::We determined the effects of soluble or coated nanocrystalline hydroxyapatite paste (nano-HA) and enamel matrix derivative (EMD) on proliferation, adhesion, and migration of periodontal ligament fibroblasts (PDLs). Cultured PDLs were stimulated with nano-HA paste or EMD in a soluble form or were coated to the surface ...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-011-0570-7
更新日期:2012-06-01 00:00:00
abstract:OBJECTIVES:Τhis study aims at determining the ability of cone beam computed tomography (CBCT) to visualize critical-size defects (CSD) created at rat calvaria and filled with 75/25 w/w nano-hydroxyapatite/chitosan (nHAp/CS) scaffolds, prior to their histological investigation. MATERIALS AND METHODS:Thirty adult Spragu...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-019-02939-4
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVES:Periodontitis is associated with systemic inflammation, elevated platelet activation and enhanced risk for cardiovascular diseases, while periodontal treatment reduces tissue inflammation and shows desirable effects on the oral biofilm and dental health. However, subgingival debridement during conservative t...
journal_title:Clinical oral investigations
pub_type: 临床试验,杂志文章
doi:10.1007/s00784-019-03049-x
更新日期:2020-05-01 00:00:00
abstract::The purpose of this 4-day plaque regrowth study was to assess the effect of N-chlorotaurine (NCT) mouth rinses on plaque inhibition and plaque vitality. Eighty volunteers participated in this investigator-blind, randomized, clinical controlled study in parallel groups. No oral hygiene was permitted except rinsing with...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-008-0207-7
更新日期:2009-03-01 00:00:00