Abstract:
:Previous work showed that a single application of 40% chlorhexidine varnish, EC40, reduced plaque acidogenicity upon sucrose challenge during less than 3 weeks. It was questioned whether lactic acid production could be reduced significantly longer when the treatment was intensified. Therefore, the effects of three consecutive EC40 applications on plaque acidogenicity were evaluated. Nine subjects who participated in the previous study received three full mouth EC40 applications within 1 week. Before the first application and up to 9 weeks after the third application, plaque samples were taken after a 10% sucrose rinse and analyzed for organic acids with capillary electrophoresis. At baseline, the mean provoked lactic acid concentration was 1.64 (+/-0.69) micromol/mg protein. At the first and seventh day after the third application, there was too little plaque to measure acid concentrations. At 2 weeks after the third application, lactic acid concentrations were significantly reduced (p < 0.05). The acid concentrations 3 weeks after the third application (1.61 (+/-0.99) micromol/mg protein) did not differ from the values at baseline (paired T test, p > 0.05). We conclude that a triple 40% chlorhexidine varnish treatment did not affect plaque acidogenicity for more than 3 weeks. From comparison with a previous study, we conclude that the triple treatment with EC40 within 1 week was not more effective in reducing plaque acidogenicity than the single one.
journal_name
Clin Oral Investigjournal_title
Clinical oral investigationsauthors
Gerardu VA,Buijs MJ,ten Cate JM,van Loveren Cdoi
10.1007/s00784-006-0079-7subject
Has Abstractpub_date
2007-03-01 00:00:00pages
77-81issue
1eissn
1432-6981issn
1436-3771journal_volume
11pub_type
杂志文章abstract:OBJECTIVES:To evaluate the marginal and internal fit of CAD/CAM-generated frameworks for 4-unit, fixed dental prostheses (FDPs) from zirconia (Z) and cobalt-chromium alloy (C) made with conventional (CI) and digital impressions (DI). MATERIALS AND METHODS:A titanium model was digitized with an intraoral scanner (DI, L...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-015-1513-5
更新日期:2016-03-01 00:00:00
abstract::The present study focuses on the correlation between the expression pattern of β-catenin (component of Wnt signaling), ΔNp63 (proliferation marker), and Notch 1 (transmembrane receptor) in oral squamous cell carcinoma. The study also aims to investigate the interaction between β-catenin and ΔNp63 in oral cancer. Furth...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-011-0605-0
更新日期:2012-08-01 00:00:00
abstract:OBJECTIVES:To determine the frequency of oral infection with potential for spread (OIPS) and behavioural risk factors in patients referred to a regional tertiary care-centre for OIPS assessment and clearance. MATERIALS AND METHODS:A database search of all referrals to the Oral and Maxillofacial Diseases unit of HUH in...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-018-2518-7
更新日期:2019-02-01 00:00:00
abstract:OBJECTIVES:Nitrogen-containing bisphosphonates induce osteonecrosis mostly in the jaw and less frequently in other bones. Because of the crucial role of periosteal perfusion in bone repair, we investigated zoledronate-induced microcirculatory reactions in the mandibular periosteum in comparison with those in the tibia ...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-014-1347-6
更新日期:2015-07-01 00:00:00
abstract:OBJECTIVES:Recent scientific evidences suggest a relevant role of the oral cavity in the transmission and pathogenicity of SARS-CoV-2. METHODS:A literature search was performed in PubMed, up to April 30, 2020, focusing on SARS-CoV-2, COVID-19, oral cavity, and antimicrobial agents. RESULTS:Oral viral load of SARS-CoV...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03413-2
更新日期:2020-08-01 00:00:00
abstract:OBJECTIVES:Periodontitis is associated with systemic inflammation, elevated platelet activation and enhanced risk for cardiovascular diseases, while periodontal treatment reduces tissue inflammation and shows desirable effects on the oral biofilm and dental health. However, subgingival debridement during conservative t...
journal_title:Clinical oral investigations
pub_type: 临床试验,杂志文章
doi:10.1007/s00784-019-03049-x
更新日期:2020-05-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-011-0595-y
更新日期:2012-08-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-016-1730-6
更新日期:2016-12-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-013-1114-0
更新日期:2014-01-01 00:00:00
abstract::Regular screening through white light inspection of the entire oral mucosa is the most important examination method to identify precancerous lesions and early oral carcinoma. Additionally, the physiologic autofluorescence of the oral mucosa has been described as a novel screening method for the detection of mucosal le...
journal_title:Clinical oral investigations
pub_type: 临床试验,杂志文章
doi:10.1007/s00784-010-0455-1
更新日期:2011-12-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-019-03138-x
更新日期:2020-08-01 00:00:00
abstract:OBJECTIVES:The aims of this study were to investigate the antimicrobial efficacy of antiseptics in saliva-derived microcosm biofilms, and to examine phenotypic adaption of bacteria upon repeated exposure to sub-inhibitory antiseptic concentrations. METHODS:Saliva-derived biofilms were formed mimicking caries- or gingi...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03613-w
更新日期:2020-10-08 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-016-1901-5
更新日期:2017-05-01 00:00:00
abstract:OBJECTIVES:To assess the potential influence of systemic antibiotic administration on the healing of periodontal intrabony defects treated with deproteinized bovine bone mineral (DBBM) and collagen membrane. MATERIALS AND METHODS:Forty-one intrabony defects were treated by means of DBBM and collagen membrane (GTR). Po...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03616-7
更新日期:2020-10-13 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-017-2206-z
更新日期:2018-04-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-017-2308-7
更新日期:2018-07-01 00:00:00
abstract::The purpose of the present study was to examine the effects of a newly developed water-soluble reduced chitosan on Streptococcus mutans, plaque regrowth, and biofilm vitality. A 1.0%, water-soluble reduced chitosan, with pH ranging from 6.0 to 6.5, molecular weights between 3,000 and 5,000 Da, and 70% degree of deacet...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-006-0038-3
更新日期:2006-06-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03377-3
更新日期:2021-01-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-010-0391-0
更新日期:2011-06-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-013-1105-1
更新日期:2014-05-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-007-0173-5
更新日期:2008-09-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-021-03778-y
更新日期:2021-01-11 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-019-03177-4
更新日期:2020-09-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-018-2777-3
更新日期:2019-09-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章,多中心研究
doi:10.1007/s00784-015-1462-z
更新日期:2015-12-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-019-02845-9
更新日期:2019-11-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章,meta分析
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更新日期:2019-07-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-014-1290-6
更新日期:2015-04-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-018-2441-y
更新日期:2019-01-01 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-008-0236-2
更新日期:2009-09-01 00:00:00